In order to improve the separate production effect of sandstone reservoir in Huabei Oilfield and give full play to the production capacity of medium and low permeability layers, the intelligent separate production technology with cable is designed and developed. The technology uses cable packer to seal each layer in the well, and a set of intelligent separate production device is connected to the corresponding string position of each target layer. During the production process, the intelligent separate production device can send instructions according to the ground control center Open or close the oil layer to realize the exploitation of any layer and multi-layer co production of any layer. It can accurately measure the liquid production and properties of each section of the well, and calculate the formation permeability, skin factor and other parameters by sections, so as to realize the continuous testing and monitoring function.In the later stage, the switch opening can be adjusted by remote control to adjust the output of each layer in time to meet different production allocation requirements and achieve the purpose of increasing oil and reducing water, which is of great significance to realize the accurate development of the reservoir.