Latest Information Research Articles

Multimodal AI Combining Clinical and Imaging Inputs Improves Prostate Cancer Detection.

Deep learning (DL) studies for the detection of clinically significant prostate cancer (csPCa) on magnetic resonance imaging (MRI) often overlook potentially relevant clinical parameters such as prostate-specific antigen, prostate volume, and age. This study explored the integration of clinical parameters and MRI-based DL to enhance diagnostic accuracy for csPCa on MRI. We retrospectively analyzed 932 biparametric prostate MRI examinations performed for suspected csPCa (ISUP ≥2) at 2 institutions. Each MRI scan was automatically analyzed by a previously developed DL model to detect and segment csPCa lesions. Three sets of features were extracted: DL lesion suspicion levels, clinical parameters (prostate-specific antigen, prostate volume, age), and MRI-based lesion volumes for all DL-detected lesions. Six multimodal artificial intelligence (AI) classifiers were trained for each combination of feature sets, employing both early (feature-level) and late (decision-level) information fusion methods. The diagnostic performance of each model was tested internally on 20% of center 1 data and externally on center 2 data (n = 529). Receiver operating characteristic comparisons determined the optimal feature combination and information fusion method and assessed the benefit of multimodal versus unimodal analysis. The optimal model performance was compared with a radiologist using PI-RADS. Internally, the multimodal AI integrating DL suspicion levels with clinical features via early fusion achieved the highest performance. Externally, it surpassed baselines using clinical parameters (0.77 vs 0.67 area under the curve [AUC], P < 0.001) and DL suspicion levels alone (AUC: 0.77 vs 0.70, P = 0.006). Early fusion outperformed late fusion in external data (0.77 vs 0.73 AUC, P = 0.005). No significant performance gaps were observed between multimodal AI and radiologist assessments (internal: 0.87 vs 0.88 AUC; external: 0.77 vs 0.75 AUC, both P > 0.05). Multimodal AI (combining DL suspicion levels and clinical parameters) outperforms clinical and MRI-only AI for csPCa detection. Early information fusion enhanced AI robustness in our multicenter setting. Incorporating lesion volumes did not enhance diagnostic efficacy.

University Management System

University Management System (UMS) is designed to automate the everyday operations of administrative, academic functions in higher degree education institutions. UMS are using integrated features like online registration for students, administration file maintenance of colleges faculty details course scheduling fee transactions academic performance monitoring in simple manner. We have seen an incredible change in thesesystems over the years, largely due to increased demands for digital transformation from schools. Today, there are cloud-based access to modern UMS solutions in place which allows institutions manage their data efficiently while retaining it on secure physical storage. These systems also come with mobile capabilities that are very useful in allowing students and faculty to remain up-to-date on the latest information. Advanced data analytics has become a critical ingredient as well, enabling administrators to balance the scales through academic planning, resource allocation and performance measurement. Education institutions are increasingly using digital ways of working and UMS have enabled these organizations to streamline processes, strengthen communication channels thus making the educational journey better for all stakeholders. Keywords— University Management System (UMS), higher education, administrative automation, academic processes, cloud-based access, mobile-friendly interface, data analytics, student registration.

Decolonizing the Library: Considering the Movement in the Irish Colonial Contexts

Abstract Decolonization is a concept which has been rapidly gaining traction in the library community, particularly in England, the United States, and Australia. This article addresses the question: “what does decolonizing the library look like in the Irish colonial contexts?” The role which libraries play in reckoning with colonial pasts cannot be understated. This paper will explore what decolonization can look like through Irish libraries both north and south of the border. This will be examined through Irish language revitalization, the presence of oral histories in library collections, and how libraries respond to underserved communities. This study also establishes areas for further research in this nascent field as well as outlining practical steps to implement the concept of decolonizing the library in the Irish contexts. Drawing on qualitative data pulled from interviews this paper will offer the latest information on the Irish library landscape and its relation to the broader decolonization movement. This paper aims to demonstrate the value of using the decolonization framework to address the colonial past which has impacted the way in which the information services function in modern day Ireland and pave the way towards an inclusive and equitable future.

Pesticide pollution: toxicity, sources and advanced remediation approaches.

The Food and Agricultural Organization of the United Nations (FAO) estimates that food production must rise by 70% to meet the demands of an additional 2.3 billion people by 2050. This forecast underscores the persistent reliance on pesticides, making it essential to assess their toxicity and develop effective remediation strategies. Given the widespread utilisation of pesticides, it requires an urgent need to evaluate their toxicity and explore feasible remediation approaches for their removal. Hence, this review provides an overview of the latest information on the presence, distribution, sources, fate, and trends of pesticides in global environmental matrices, emphasizing the ecological and health risks posed by pesticide pollution. Currently, the dominant remediation techniques encompass physical, chemical, and biological methods, yet studies focusing on advanced remediation techniques remain limited. This review critically evaluates both newer and traditional approaches to pesticide removal, offering a descriptive and analytical comparison of various methods. The selection of the appropriate treatment method depends largely on the nature of the pesticide and the effectiveness of the chosen technique. In many cases, technologies such as membrane bioreactors and the fenton process could be integrated with biological technologies to enhance performance and overcome limitations. The study concludes that a hybrid approach combining various remediation strategies offers the most effective and sustainable solution for pesticide removal. Finally, the review underscores the need for further scientific investigation into the most viable technologies while discussing the challenges and prospects of developing safe, reliable, cost-effective, and eco-friendly methods for removing pesticides from the environment.

DIGITALIZATION OF THE TAX SYSTEM IN EUROPE

In the context of the highly increasing dispersion of technology in the European economic environment, the interaction of citizens with the public sector is changing rapidly. European countries have significant differences on the tax collection, generating economic effects under a complex fiscal system. The purpose of this study is to analyse the effects of digitalization on the VAT compliance gap in the European Union countries. The analysis considers the VAT compliance gap as the dependent variable and examines the influence of E-government activities of individuals via websites as an independent variable, as a relevant indicator of digitalization. The research approach methodology consisted in EViews Granger causality tests for the collected data from the EU sources, for a period of ten years (2012-2021). The study results revealed relevant insights and latest information about the connection between e-government users and the VAT compliance gap. This relationship is particularly notable as it emphasizes the potential of digitalization in uplifting tax compliance and improving VAT collection. Studying the impact of digitalization on VAT compliance, the research is intent to provide to the economist, policymakers, and students a deeper understanding of the technology’s impact on tax policies and economic outcome.

IgA Vasculitis (Henoch-Schönlein Purpura): An Update on Treatment.

Objective: IgA vasculitis (IgAV), previously named as Henoch-Schönlein purpura, is the most frequent systemic vasculitis in children. In adults, IgAV is less common although it is associated with more severe disease. In fact, the frequency of glomerulonephritis (referred to as IgAV nephritis) in adults is higher than in children and tends to present more severely, with around 10-30% of those affected eventually progressing to end-stage renal disease. In this review, we describe the pathophysiology, main clinical features, diagnosis of the disease, and latest clinical data regarding IgAV therapy. Methods: A narrative literature review, primarily based on articles published in PubMed, was conducted. In addition to discussing the main aspects of glucocorticoids and conventional disease-modifying drugs used in the management of IgAV, this review focuses on the latest information reported regarding biologics and potential future therapies. Results: Glucocorticoids are the first-line therapy for IgAV, especially in adults with severe manifestations. Colchicine, dapsone, and methotrexate can be useful for controlling minor manifestations. Several immunomodulatory agents, such as cyclosporine A, tacrolimus, and mycophenolate mofetil, have shown favorable results as glucocorticoid-sparing agents. Leflunomide has shown promising results but requires further study. The use of rituximab has demonstrated efficacy in reducing relapse frequency, lowering the cumulative glucocorticoid burden, and achieving long-term remission of the disease in children and adults with IgAV. Immunoglobulins and plasma exchange therapy can also be useful in difficult and life-threatening situations. Other potential therapies with encouraging results include TRF-budesonide, B-cell-directed therapy, B-cell-depleting agents, sodium-glucose cotransporter-2 inhibitors, endothelin receptor antagonists, and complement pathway inhibitors. Conclusions: Glucocorticoids are the first-line therapy for IgAV, especially in adults with severe manifestations. The role of various immunomodulatory therapies, such as calcineurin inhibitors and mycophenolate mofetil, remains promising, while rituximab reduces the long-term side effects of glucocorticoids and can help achieve disease remission. Other potential therapies with encouraging results require further research.

Advancements in Contemporary Pharmacological Innovation: Mechanistic Insights and Emerging Trends in Drug Discovery and Development

Developing a new drug and bringing it to the market is a complex and time-consuming process that involves multiple phases of drug discovery and development. However, recent advancements in various technologies, such as multi-omics, genome editing, Artificial Intelligence (AI), and Machine Learning (ML), have significantly improved this process. These technologies have made the process more accurate, less time-consuming, and cost-effective compared to the conventional methods of drug discovery and development. In the current age, discovering and developing drugs is a collaborative effort that involves scientific breakthroughs, technological advancements, and regulatory oversight. The pharmaceutical industry is constantly innovating new techniques, fostering interdisciplinary collaboration, and prioritizing patient-centered approaches. In this review, we explore the latest and most updated information about using advanced technologies in drug discovery. The review begins by briefly explaining the conventional drug discovery and development process, and then delves into the applications of multi-omics, genome editing technology, systems biology, artificial intelligence, and machine learning.

Current Updates on Variants of SARS-CoV- 2: Systematic Review.

Coronavirus disease 2019 is caused by the severe acute respiratory syndrome coronavirus 2, which has become a pandemic. Severe acute respiratory syndrome coronavirus 2 is an enveloped, unsegmented, positive-sense, single-stranded RNA virus that belongs to the family Coronaviridae. The objective of this review is to conduct a qualitative analysis of the current updates on epidemiology, evolution, and vaccine variants for SARS-CoV-2. The search strategy was done from the database based on the PRISMA criteria for qualitative analysis of this review. Literature on variants of severe acute respiratory syndrome coronavirus 2, published in English in the last 5 years (2019-2023), were included. From 179 a total of 105 articles were reviewed, searched, and retrieved from the electronic databases PubMed. The search was done using keywords like COVID-19, SARS-CoV-2, variants, mutations, and vaccines, and articles were managed using EndNote X8 software. The scope of view for this review was the course of the pandemic by emerging variants and how man is struggling to overcome this sudden pandemic through vaccines. The narrative skeleton was constructed based on the article's scope of view. From the parent severe acute respiratory syndrome coronavirus 2, many variants emerged during the course of this pandemic. They are mainly categorized into two variants: variants of interest and variants of concern based on the impact on public health. The World Health Organization leveled five variants: Alpha (strain B.1.1.7), Beta (strain B.1.351), Gamma (strain P.1), Delta (strain B.1.617.2), and Omicron (B.1.1.529). It is crucial to stay informed about the latest developments in the understanding of SARS-CoV-2 variants, as new variants can emerge and impact the course of the pandemic. Health authorities and researchers continuously have to monitor and study these variants to assess their characteristics, transmissibility, severity, and the effectiveness of vaccines against them. One has to always refer to the latest information from reputable health journals or organizations for the most up-to-date and accurate details on COVID-19 variants.

Strengthening Indonesia’s health system through community and technological engagements in public health interventions

The 7th International Symposium on Public Health (ISoPH 2023), was held on October 2-3, 2023, in Surabaya, Indonesia, which brought together a diverse array of public health professionals, researchers, and policymakers from around the globe. The purpose of the symposium was to facilitate the exchange of the latest information and ideas within the realm of public health. The symposium aspired to foster discussions and the exchange of insights regarding scientific issues in the field of public health globally and within the context of Indonesia. Organized by the Faculty of Public Health at Airlangga University in Indonesia, the symposium addressed the urgent need for robust, resilient health systems capable of navigating the complex challenges of the modern era, particularly in the context of the Society 5.0 paradigm.

Atopic Dermatitis-Related Problems in Daily Life, Goals of Therapy and Deciding Factors for Systemic Therapy: A Review

Background/Objectives/Methods: Atopic dermatitis (AD) impacts various aspects of patients’ lives including personal life, psychological aspects/disturbances (e.g., depression, anxiety, or even suicidal thoughts), school, and work-related activities, including career advancement. The aim of this narrative review is to present the latest information available on how to best approach AD patient management, as well as decisions regarding standard/advanced systemic therapy, by gathering evidence from the relevant medical literature (PubMed and other prominent medical databases). Results: Thus, AD patient management and decisions regarding advanced/systemic therapy are complex, requiring the consideration of multiple disease-related factors: age; disease severity; patient medical history and comorbidities; previous topical therapy use and any adverse reactions; treatment efficacy concerns; patient preferences, expectations and fears; pregnancy planning; ability and willingness to adhere to the treatment regimen; impact on related risks; and any associated psychological or psychiatric issues. Current guidelines and systematic reviews support the safety and efficacy of systemic therapy including conventional drugs (cyclosporine, methotrexate, and azathioprine), biologics (dupilumab and tralokinumab), and JAK inhibitors (baricitinib, upadacitinib, and abrocitinib) recommended for treating moderate and severe AD. Recently, additional biologics have been evaluated in clinical trials, including lebrikizumab, nemolizumab, eblasakimab, and OX40/OX40L, among others. Conclusions: The most recently suggested approach to treating AD patients suggests focusing on therapy that targets and achieves minimal disease activity (MDA), where therapy decisions are informed by both the patient and the clinician. Available data also indicate the importance of a personalized, stepwise, and multidisciplinary approach. This type of approach promotes patient compliance, satisfaction with therapy, and increased engagement, which all lead to better patient outcomes.

The Phenomenon of Fear of Missing Out Instagram Social Media in Generation Z in the 2024 Presidential Election

In the current digital era, Instagram is not only a place to share personal moments but also a political arena where individuals participate in discussions, campaigns, and other political activities. This research aims to understand the phenomenon of Fear of Missing Out (FoMO) on social media, Instagram, among Generation Z during the 2024 presidential election using Alfred Schutz's phenomenological theory. This research employs the phenomenological method, where data collection techniques used are interviews, observations, and documentation. The study uses an interpretive paradigm to allow the researcher to observe and understand the meanings, values, and behaviors of Generation Z in using Instagram to spread campaign tweets and even comment during the 2024 presidential election. The results of this research show that Generation Z feels a greater desire to use Instagram during the presidential election period. FoMO is a common experience among the informants, particularly related to the fear and anxiety of missing out on important information or discussions happening on Instagram during the 2024 presidential election. The FoMO experienced by the informants indicates a pressure to always stay up-to-date with the latest information, which can negatively impact the informants.

Pemberdayaan Pelaku UMKM Perikanan Melalui Digitalisasi di Kabupaten Maluku Tengah dengan Metode ABCD

Central Maluku Regency MSMEs are dominated by players in the fisheries sector, due to the abundant potential for marine products in the area. But unfortunately the abundance of marine products is not directly proportional to the income of the people there. The main objective of this research activity is to increase MSMEs' understanding of the importance of digitalization in the 4.0 revolution era and to improve MSMEs' abilities and skills regarding business management from upstream to downstream using the latest technology and information in order to increase income. The method for implementing this research activity uses the ABCD (Asset Base Community Development) approach which prioritizes the use of assets and potential that exist around the community for sustainable economic growth to form community independence in increasing income so that their welfare will also increase. Coupled with a SWOT analysis to identify internal and external factors in the state of Central Maluku Regency MSMEs. The results of this research are that MSEs need to be given training in Market Research, Branding, Digital Literacy and Financial Literacy.

Analisis Usability Website PT. Perkebunan Nusantara (PTPN IX) Untuk Menunjang Industri Kreatif di Era Global

Technology is rapidly advancing in society and the workplace. PT Perkebunan NusantaraIX (PTPN IX), which operates in the management and marketing of plantationcommodities, has utilized technology to facilitate the presentation of downstream productinformation through a dynamic website. The PTPN IX website plays a crucial role inpresenting the company's latest information. However, the PTPN IX website has neverundergone a usability testing process. Therefore, this study aims to analyze the quality ofthe website in supporting its role and functions. The results of the observations indicate thatseveral users experience problems when accessing the website. To analyze these issues,heuristic evaluation methods were used to identify usability problems on the website, andthe System Usability Scale (SUS) to assess the system's feasibility. This method involved3 evaluators and 100 users to evaluate the website based on 10 heuristic aspects, whichwere mapped into sub-aspects according to their severity levels. The overall evaluationresults indicated categories of cosmetic issues and minor usability problems. This studyidentified 10 problems and provided recommendations for improving the PTPN IXwebsite. The improvement recommendations aim to optimize the website system to betterfulfill its role and function as an information provider platform related to local commodityproducts for all elements of society.

Pengembangan Antarmuka Pengguna (User Interface) Sistem Pengelolaan Beasiswa Berbasis Website dengan Pendekatan Cognitive Walkthrough

An effective user interface (UI) is crucial in a web-based scholarshipmanagement system to ensure a good user experience and easy accessibility toinformation. However, many users still encounter difficulties using the existingsystem, necessitating a better design. This study aims to evaluate and improve theuser interface of the scholarship management system using the CognitiveWalkthrough approach. The Cognitive Walkthrough approach is used to identifyusability issues in the user interface. A prototype of the design solution was thentested through usability testing involving seven evaluators and five different taskscenarios using Maze. The results show that all evaluators were able to completethe task scenarios with a category 1 rating (no issues), although four evaluators experienced minor issues in task scenarios 1 and 2. Evaluators were slightlyconfused when searching for the latest requirements information and the ineffectiveuse of buttons. By implementing the suggested improvements based on the findingsfrom the Cognitive Walkthrough, the user interface in the scholarship managementsystem can be significantly enhanced, facilitating users in accessing the requiredinformation.

Updating information of mycoses and antifungal medicines to find effective platforms for the production of new thiazole compounds

Introduction. Information about mycoses and antifungal drugs of the modern type is often fragmentary and unsystematic, which requires correction.Aim. To systematize the latest information about fungi and mycoses, means of combating them and the problems encountered along the way, to highlight the latest achievements in the field of synthesis and research of the activities of 1,2,4-triazole as a potential fungicidal compound.Materials and methods. The materials were the authors' research published in advanced scientific journals, conducted around the world in the field of studying fungi, antifungal drugs, and the search for new antifungal agents.Results and discussion. The article provides an overview of current information on the morphobiological features of fungi, updating their taxonomy and nomenclature, shows the role of fungi in nature and the development of fungal infections in humans and animals, structured information on the classification of mycoses and their pathogens. The latest information is also provided on the pharmacological properties of the main currently existing antifungal drugs, the mechanisms of formation of resistance to them in fungi, in a comparative aspect with other groups of antimycotic drugs, the prospects of azoles and their derivatives as new fungicidal drugs and disinfectants are shown. Literature studies have shown that 1,2,4-triazole derivatives have a wide range of antifungal activity, which extends to other types of activity.Conclusion. It was noted that the significant prospects of triazoles are due, among other things, to the fungicidal effect on resistant strains of fungi-pathogens of human and animal infections. The advantage of the new derivatives is the low level of concentrations suppressing fungi, low cytotoxicity, which allows them to be used for intravenous administration in the future. Updating information on the effectiveness of new antifungal compounds will help researchers systematize knowledge about the properties of azoles, which can contribute to the search and development of new potential candidates for antifungal drugs with high efficiency and selectivity, and contribute to the formation of new research directions for the search for effective means of combating mycoses in various fields of human activity.

Pharmacognostic, phytochemical and pharmacological activities of Ocimum kilimandscharicum Guerke

The family Lamiaceae encompasses a diverse array of therapeutic plants, with the genus Ocimum being particularly esteemed. The plant known as Kapur Tulsi in India, Ocimum kilimandscharicum Guerke is a perennial woody shrub characterized by its essential oil, which predominantly contains camphor, along with linalool, limonene, eugenol, 1,8-cineole, and camphene. This review aims to provide current information on the taxonomy, botany, distribution, ethnomedicinal uses, phytochemistry, pharmacology, and toxicological profile of O. kilimandscharicum. The information presented was critically analyzed to understand the current research on this species and to explore potential future opportunities for this plant in pharmaceutical research. A comprehensive literature search was conducted and relevant information was collected through an extensive exploration of bibliographic databases, including Google Scholar, ScienceDirect, PubMed, Web of Science, Semantic Scholar, Europe PMC, and Scopus. The literature suggests that the plant contains a range of compounds that underpin its broad spectrum of pharmacological effects. These phytoconstituents have been widely employed in the treatment and management of numerous conditions. This review consolidates the latest information on its phytochemical and pharmacological activities, traditional applications, and scientific research. The review highlights the significant phytoconstituents of Ocimum kilimandscharicum Guerke and summarizes the evidence supporting its pharmacological potential. The findings suggest that the plant's diverse compounds contribute to its extensive use in traditional medicine and underscore its potential for therapeutic applications in various diseases.

Pemphigoid Gestationis - literature review

Introduction and Objective: Pemphigoid gestationis (PG) is a rare, self-limiting autoimmune disorder, typically appearing in the second or third trimester of pregnancy. It can lead to postpartum exacerbations, and studies suggest an increased risk of preterm birth and the development of Graves' disease in the mother. The aim of this article is to gather the latest information on pemphigoid gestationis. Review Methods: A review of studies available in the PubMed database was conducted using the keywords "pemphigoid gestationis" and "dermatoses of pregnancy" in order to find publications from the last 8 years. Brief Description of the State of Knowledge: Pemphigoid gestationis (PG) is characterized by the production of IgG1 antibodies against bullous pemphigoid antigen 180 (BP180). The primary symptom of PG is intense itching, which often occurs before skin lesions develop. Diagnosis is typically confirmed through direct immunofluorescence (DIF) of perilesional skin. Treatment focuses on relieving itching and preventing new blister formation, usually starting with topical corticosteroids for mild cases, while systemic corticosteroids are reserved for more severe presentations. Recent research indicates that biologic therapies may also offer effective management options for PG. Summary: The authors highlight the need for further research due to the limited sample sizes in existing studies, as well as the potential complications during pregnancy and long-term health effects.

A Critical Review of Deep Oxidation of Gaseous Volatile Organic Compounds via Aqueous Advanced Oxidation Processes.

Volatile organic compounds (VOCs) are considered to be the most recalcitrant gaseous pollutants due to their high toxicity, diversity, complexity, and stability. Gas-solid catalytic oxidation methods have been intensively studied for VOC treatment while being greatly hampered by energy consumption, catalyst deactivation, and byproduct formation. Recently, aqueous advanced oxidation processes (AOPs) have attracted increasing interest for the deep oxidation of VOCs at room temperature, owing to the generation of abundant reactive oxygen species (ROS). However, current reviews mainly focus on VOC degradation performance and have not clarified the specific reaction process, degradation products, and paths of VOCs in different AOPs. This study systematically reviews recent advances in the application of aqueous AOPs for gaseous VOC removal. First, the VOC gas-liquid mass transfer and chemical oxidation processes are presented. Second, the latest research progress of VOC removal by various ROS is reviewed to study their degradation performances, pathways, and mechanisms. Finally, the current challenges and future strategies are discussed from the perspectives of synergistic oxidation of VOC mixtures, accurate oxidation, and resource utilization of target VOCs via aqueous AOPs. This perspective provides the latest information and research inspiration for the future industrial application of aqueous AOPs for VOC waste gas treatment.

Associations of Microbiota and Nutrition with Cognitive Impairment in Diseases

Background/Objectives: Recent research highlights the growing interest in the impact of nutrition on cognitive health and function in disease, as dietary habits are increasingly recognized as crucial factors in relation to brain function. This focus is especially important given the rising prevalence of neurodegenerative diseases and the cognitive decline associated with poor dietary choices. Links are now being sought between brain function and the microbiota and gut–brain axis. Mechanisms are proposed that include low-grade chronic neuroinflammation, the influence of short-chain fatty acids, or the disruption of glial cells and transmitters in the brain. Methods: We reviewed the articles on pubmed. This is not a systematic review, but of the narrative type. We wanted to outline the issue and summarise the latest information. Results: The axis in question has its foundation in nutrition. It has been reported that diet, particularly the components and the timing of food intake, has an impact on cognitive processes. The Mediterranean diet is most often cited in the literature as being beneficial to health. In order to obtain a more complete view, it is worth considering other dietary patterns, even those that impair our health. Conclusions: Determining what is beneficial and what is not will allow us to develop a speronized strategy for the prevention of, and fight against, cognitive impairment. Appropriately selected supplements, the functions of which we have also discussed, may prove supportive.

Multi-Stage Rolling Grid Expansion Planning for Distribution Networks Considering Conditional Value at Risk

Existing single-stage planning and multi-stage non-rolling planning methods for distribution networks have problems such as low equipment utilization efficiency and poor investment benefits. In order to solve the above problems, this paper firstly proposes a multi-stage rolling planning method for distribution networks based on analyzing the limitations of the existing planning methods, which divides the planning cycle of the distribution network into multiple planning stages, and makes rolling amendments to the planning scheme of each stage according to the latest information during the planning cycle. Then, a multi-stage rolling planning model of distribution network taking into account conditional value at risk is established with the objective of minimizing the total investment and operation cost of the distribution network. On the one hand, the users’ electricity bill is taken into account in the objective function, and the necessity of this part of the benefits is demonstrated. On the other hand, the conditional value at risk is used to quantify the uncertainty of the operation cost in the process of the expansion planning of the distribution network, which reduces the operation cost risk of the distribution network. Next, this paper uses the rainflow counting method to characterize the capacity decay characteristics of energy storage in the distribution network, and proposes an iterative solution framework that considers energy storage capacity decay to solve the proposed model. Finally, the proposed method is applied to an 18-node distribution network planning case. This confirms that the multi-stage rolling planning method could improve the investment benefits and reduce the investment cost by approximately 27.27%. Besides, it will increase the total cost by approximately 2750 USD in the case if the users’ electricity bill is not taken into account. And the maximum capacity of energy storage may decay to 87.6% of the initial capacity or even lower during operation, which may cause the line current to exceed the limit if it is not taken into account.