Large Number Of Sexual Partners Research Articles

Predictors of Precancerous Diseases of the Cervix

Introduction. The incidence of malignant neoplasms in the population has increased by 1.66 times over the past 15 years, and the incidence of cancer of the cervix and body of the uterus, placenta — by 1.3 times.Materials and methods. 2 groups were formed by the continuous sampling method: 30 women with a diagnosis of cervical intraepithelial neoplasia (CIN) and 30 women without a diagnosis of CIN, who made up the control group. Statistical analysis was carried out using the StatTech 3.1.7 program (Stattech LLC, Russia).Results. Risk factors for precancerous diseases of the cervix include the presence of a history of cardiovascular diseases(p = 0.043), surgical interventions (p = 0.039), sexually transmitted infections (p = 0.023), a large number of pregnancies (regardless of the outcome) (p = 0.013), the presence of abortions (p = 0.04), a large number of sexual partners during life (p = 0.022).Discussion. Frequent change of sexual partners, and as a consequence — a high risk of STIs are also well-known risk factors for cancer and precancerous cervix, in these conditions HPV passes from free to episomal form faster and starts the process of transformation of cervical epithelial cells.Conclusion. The features of the anamnesis of women with precancerous diseases of the cervix are high parity and the presence of abortions, STIs, cardiovascular diseases and surgical interventions in the anamnesis, a large number of sexual partners in life, low adherence to the use of combined oral contraceptives (COCs).

TH44. LEVERAGING DNA METHYLATION QUANTITATIVE-TRAIT LOCI TO CHARACTERIZE THE RELATIONSHIP BETWEEN METHYLOMIC VARIATION, GENE EXPRESSION, AND PSYCHIATRIC DISEASE

To determine the prevalence of Chlamydia trachomatis (CT) in the population screened at sexually transmitted infection (STI) clinics on Reunion Island and to identify risk factors for CT infection.This cross-sectional multicenter study was conducted in 2017–2018. Data were obtained from self-administered questionnaires and multiplex PCR tests.The overall prevalence of CT in the screened population was 8.6% (95% CI 7.7–9.5%). The prevalence of urogenital CT was highest in women under 18 (13.2%, 95% CI 9.3–18.1%) and in men who have sex with men under 18 (13.3%, 95% CI 1.6–48.2%). Risk factors associated with CT infection in multivariate analysis were: female gender, being born in Reunion Island, having had a large number of sexual partners in the past year, and being co-infected with another STI.The prevalence of CT in the screened population is higher in Reunion Island than in mainland France, especially in minors. Prevention campaigns targeting minors should be strengthened.

Minors are the most affected by Chlamydia trachomatis in Reunion Island: A cross-sectional study, 2017–2018

ObjectivesTo determine the prevalence of Chlamydia trachomatis (CT) in the population screened at sexually transmitted infection (STI) clinics on Reunion Island and to identify risk factors for CT infection. Patients and methodsThis cross-sectional multicenter study was conducted in 2017–2018. Data were obtained from self-administered questionnaires and multiplex PCR tests. ResultsThe overall prevalence of CT in the screened population was 8.6% (95% CI 7.7–9.5%). The prevalence of urogenital CT was highest in women under 18 (13.2%, 95% CI 9.3–18.1%) and in men who have sex with men under 18 (13.3%, 95% CI 1.6–48.2%). Risk factors associated with CT infection in multivariate analysis were: female gender, being born in Reunion Island, having had a large number of sexual partners in the past year, and being co-infected with another STI. ConclusionsThe prevalence of CT in the screened population is higher in Reunion Island than in mainland France, especially in minors. Prevention campaigns targeting minors should be strengthened.

Социально-эпидемиологические закономерности распространения эректильной дисфункции у мужчин в Азербайджане

As a result of the epidemiological analysis, it was found that for the observation period from 2016 to 2018 the prevalence of erectile dysfunction (ED) in men was 36,3±3,4%. The sexual behavior of men with ED was characterized by the presence of a large number of sexual partners from the onset of sexual activity, which did not have significant statistical differences between groups. Analysis of the social status of patients showed that 107 (64,8 ± 3,7%) of the surveyed men in the main group had a higher education, while in the control group only 14 (28,0 ± 6,3%) patients (p>0,05). In 30,3±2,2% of all examined men, chronic inflammatory diseases of the male genital area (prostatitis, vesiculitis, epididymitis) prevailed. 10,6±1,4% of men had endocrine disorders (hyperprolactinemia, hypogonadism, hypergonadotropinemia), 4,9% had varicocele, 9,9% had sexually transmitted infections.

Assessment of women's knowledge about HPV vaccination in the light of the HPV infection as a risk factor for cervical cancer

Introduction Cervical cancer (CC) is one of the most prevalent malignancies of female reproductive tract. In Poland in 2017 CC accounted for 3.0% of all newly registered tumour cases among women, and was the eighth most common female malignancy. Persistent infection with carcinogenic human papillomavirus (HPV) is the leading risk facor. Currently, it is believed that infection with the human papillomavirus (HPV), especially its oncogenic types 16 and 18, is of fundamental importance in the development of cervical cancer. Vaccination prevents from infection with certain types of viruses, and consequently the development of cancer induced by a given type of virus. Therefore, their effi­cacy can be measured only in the long term, in a large cohort of vaccinated adolescents reaching the age charac­terized by the peak incidence of these cancers.Purpose The objective of the study was to evaluate knowledge about CC, as well as awareness of HPV and HPV vaccination among female respondents.Material and method The research was conducted on the group of 1,260 survey respondents, who filled out the Internet questionnaire. The obtained results were analysed and checked on the basis of scientific literature.Results The percentage of respondents who select human papillomavirus infection as a risk factor for the cervical cancer is 75.9%. The onset of intercourse at an early age was considered a risk factor by only 24.6%, while a large number of sexual partners by 45.4%. Women were also asked about knowledge of HPV vaccination. Only 73.8% of them heard about it and 26.2% declare unawarness of this type of vaccination.Conclusions Health promotion campaigns and educational programs are necessary in order to reduce cervical cancer burden and should be directed particularly towards those who have demonstrated low cervical cancer knowledge and low awareness regarding HPV and its vaccine.

Research on the knowledge of women about the risk factors for cervical cancer

Introduction: Cervical cancer (CC) is currently the eight most common cancer among women and the seventh leading cause of cancer-related death in women in Poland. Early, non-invasive cervical cancer may develop over the years without clinical symptoms. Also, given the fact that early forms are treatable effectively, it's important to get preventive examinations. It is especially important in the group of women at high risk of developing CC. Purpose: The aim of the study is to assess women's knowledge of the risk factors for cervical cancer.Material and method: Women's knowledge of cervical cancer risk factors was verified with an anonymous online questionnaire. The obtained results were analysed and checked on the basis of scientific literature.Results: The vast majority of respondents consider family history of cancer as a risk factor for CC. 75.9% of women consider infection with HPV a risk factor. Chronic vaginal infections were chosen by over half of the women. The onset of intercourse at an early age was considered a risk factor by only 24.6%, while a large number of sexual partners by 45.4%.Conclusions: The results of the conducted research indicate that the knowledge of women from the studied group about the risk factors for cervical cancer and methods of prevention is average. In order to improve the epidemiological situation of cervical cancer in Poland, efforts should be intensified to increase the education of women in this field.

Reproductive Healthcare Needs of Sex Workers in Rural South Africa: A Community Assessment.

Background:In the Limpopo province of South Africa, access and availability of women’s health services are limited and many challenges exist for a growing population of transient sex workers. This study was developed to place communities at the forefront to more specifically understand regional barriers and attitudes regarding reproductive health care needs.Objective:To build strong community partnerships, gain understanding of issues in women’s health services, and collaborate with community members to address those issues.Methods:A mixed-methods study approach was used in rural South Africa. Participants were recruited through voluntary interest from a local health clinic performing outreach for migrant female sex workers. We (1) created partnerships and built trust within the community and (2) worked collaboratively to collect both qualitative and quantitative data, using community groups to discuss health needs as well as “knowledge, attitude, and practice” (KAP) surveys.Findings:Ninety-four sex workers participated. The survey data identified risk factors to poor reproductive healthcare outcomes, including limited education, young age at first sexual contact, large number of sexual partners, little knowledge of sexually transmitted infections, distrust in the use of healthcare facilities, and limited use of contraception. Community discussion groups revealed a desire for easier and more accessible healthcare, showing the biggest barriers to care are lack of money and transportation, and safety concerns related to profession, including fear of violence from partner and/or client. With input from civic leaders, public interest, and community outreach groups, a community advisory board was successfully formed for future collaboration.Conclusion:By working with local stakeholders and sex workers, we created an interactive and tailored assessment to discuss healthcare disparities. We helped foster community ownership, setting the stage for future implementation of sustainable and cooperative health programming.

“Getting high to get laid.” Drugs and gay sex under influence.

Summary The major studies on men who have sex with men (MSM) in France (which began with Michael Pollak and Marie-Ange Schiltz forty years ago in Gay Press) introduced the idea of drug use in 1997, just after highly effective antiretroviral treatment (HAART) combinations were made available for HIV, making AIDS a manageable chronic condition. Australian researcher Kane Race identifies this time as the beginning of a “lifetime of drugs”, but the utility of surveys into the use of psychoactive substances among gay people was to emerge in the following decades, after it was discovered that ARV treatments could keep viral load at undetectable levels in HIV-positive people, who could therefore no longer infect others. In the early 2010s, the use of drugs became a major theme in surveys of gay sexuality, and in particular the use of drugs in a sexual setting, which was named “chemsex”. Men who adopt this practice tend to have intense sex lives, with a very large number of sexual partners over the past 12 months, regular attendance at sexual meeting places, specific sexual practices and do not use condoms for anal penetration. The majority who are involved are HIV-positive MSM or HIV-negative MSM on PrEP. To date, the research and publications looking at chemsex have only investigated it through the prism of the associated risks linked to addiction and compulsive behaviour. In this article we intend to show how the emergence of a scientific literature of chemsex has contributed to a masking of the strictly sexual behaviours associated with it. We will draw upon two complementary types of material: several quantitative surveys of sexual and HIV prevention behaviours among gay men and other MSM (Prevagay 2015, the 2017 “Rapport au Sexe” survey, known as ERAS). and the initial results of the APACHES survey (Attentes et PArcours lies au CHEmSex/Expectations and Experiences of Chemsex), which used biographical interviews carried out on behalf of OFDT in 2018, focusing on sexual scripts as well as the role of pleasure and contemporary ways of socialising in this subculture.

A randomized controlled efficacy trial of behavioral activation for concurrent stimulant use and sexual risk for HIV acquisition among MSM: project IMPACT study protocol

BackgroundIn the United States, problematic stimulant use is a prevalent and difficult to treat problem among men who have sex with men (MSM), as well as a major driver of HIV transmission through the large number of sexual partners and concomitant condomless anal sex (CAS). Evidence-based behavioral studies that address problematic stimulant use in MSM at risk for HIV infection are also lacking. In this paper, we describe the design of a behavioral intervention trial to reduce sexual risk behavior and stimulant use in HIV-uninfected MSM.MethodsThis study, funded by the National Institute on Drug Abuse (NIDA), is a randomized controlled trial (RCT) testing an integrated HIV risk reduction and behavioral activation counseling intervention (IMPACT) for HIV-uninfected, stimulant using MSM in Boston, MA, and Miami, FL. Participants are randomized (2:2:1) to either (1) the IMPACT intervention; (2) a relaxation condition, an active therapy time- and intensity-matched control; or (3) a standard of care risk reduction counseling comparison. At enrollment, all participants receive an HIV test and pre- and post-test counseling. The primary outcome is the difference in the rate of change in the number of self-reported condomless anal sex acts without the protection of consistent Pre-Exposure Prophylaxis (PrEP) use, as well as reductions in stimulant use during the prior 4-months. Major assessments are conducted at baseline, 4-, 8-, and 12-month follow-up visits.DiscussionEffective and sustainable behavioral interventions are sorely needed to reduce HIV acquisition in stimulant using MSM at risk for HIV infection. In this study, we will evaluate the evidence of efficacy of the IMPACT intervention to reduce HIV acquisition in HIV-uninfected, stimulant-using MSM. If found effective, the intervention tested here holds promise for being readily integrated into real-world clinical settings.Trial registrationClinicalTrials.gov number NCT03175159, registered June 5, 2017.

Ocena wiedzy kobiet na temat seksualnych czynników ryzyka raka szyjki macicy

In Poland, reproductive system cancers are an important medical and social problem. Risky sexual behaviours such as early age of sexual initiation, or a large number of sexual partners increase the risk of cervical cancer. The aim of this study was to assess the knowledge of women about sexual risk factors for cervical cancer. The study included 200 women from the cities of Lublin and Radom, and the village of Jabłonna. Respondents completed a diagnostic survey questionnaire specially developed for the purpose of this study. The results were statistically analysed. statistically signi􀏐icant relationship was found between the knowledge of respondents about early start of sexual intercourse as a risk factor for cervical cancer and their marital status (p = 0.003), place of residence (p = 0.01) and type of professional activity (p = 0.03). There was also a statistically signi􀏐icant relationship between the knowledge of the surveyed women on a large number of sexual partners as a risk factor for cervical cancer and age (p = 0.002), marital status (p = 0.03), and the type of professional activity. Women know that the early age of sexual initiation and a large number of sexual partners is a risk factor for cervical cancer. On the other hand, they are not aware of the impact of a large number of sexual partners of their current partner on the risk of cervical cancer. There is a need to educate women about the impact of risky sexual behaviour on the potential development of cervical cancer.

The importance of feeling sexually attractive: Can it predict an individual's experience of their sexuality and sexual relationships across gender and sexual orientation?

Limited research exists on the implications of feeling sexually attractive for various aspects of sexuality and sexual relationships. This article examined associations between self-perceived sexual attractiveness and sexual esteem, sexual satisfaction and amount of sexual experience, among both men and women who identified as heterosexual (n = 1017), gay or lesbian (n = 1225) or bisexual (n = 651). Results of the study demonstrated that positive self-perceptions of sexual attractiveness predicted greater sexual esteem, greater sexual satisfaction, a higher frequency of sexual activity with others and a larger number of sexual partners among both men and women who identified as heterosexual, gay, lesbian or bisexual. The findings suggest that feeling sexually attractive may have implications for how an individual experiences their sexuality and sexual relationships regardless of their gender or sexual orientation. The importance of considering an individual's self-perceptions of sexual attractiveness when they present with concerns related to their sexual experiences or relationships, and the potential benefits of educational and therapeutic interventions designed to enhance self-perceptions of sexual attractiveness are discussed.

Pornography sexual behaviour and risk behaviour at university

Summary Introduction The pornography industry is a pervasive influence on adolescents, nearly all of whom are exposed to it via the internet, either willingly or unwillingly and at a more or less premature age. Is there an association between exposure to pornography and some forms of risk behaviour? Method Eight hundred and twelve Lille students responded anonymously to a questionnaire given to them on the occasion of a consultation at a health centre. Logistic and linear regressions were used for statistical analysis. Findings Nearly all men and 80% of women had been exposed to pornography. The average age of initial exposure was 15.2 years. Exposure at a premature age is associated with sexual activity at a younger age and with a greater inclination to seek out casual partners and use cannabis more frequently. The age of exposure does not on the other hand appear to have any influence on the number of sexual partners, the practice of anal penetration, alcohol or tobacco consumption, contraceptive use and taking risks in terms of sexually transmitted infections. Frequent viewing of pornographic images is associated with sexual activity at a younger age, a larger number of sexual partners, an inclination to seek out casual partners, the practice of anal penetration, a lower level of prevention of sexually transmitted infections and unwanted pregnancies and finally, a higher consumption of alcohol and cannabis. In conclusion, these findings should be taken into account, and should lead those involved in sexual health and sex education to increase the amount of information they provide to adolescents.

Differences in risk factors for cervical dysplasia with the applied diagnostic method in Serbia.

In the etiology of cervical cancer not only HPV infection is important, but also other factors such as demographic influences and sexual and reproductive health attitudes, as well as others related to preventive measure usage (or non usage). The aim of this study was to examine factors associated with cervical dysplasia in asymptomatic women who were examined by routine cytology and cervical biopsy for early detection of cervical cancer. Socio-demographic and other characteristics were obtained from medical files of 85 examinees with pathologic cytologic findings (Pap test) and histopathologic (HP) findings after biopsy. According to the Pap test result, a greater probability for development of cervical dysplasia was noted with examinees having a larger number of sexual partners (OR= 5.01, 95% CI 1.04-24.10), and those who are afraid of the Pap finding. Risk factors for development of cervical dysplasia according to the bioptic finding were early beginning with sexual activities, presence of any STD in personal medical history and fear of the Pap test finding. The only risk factor found to be important for both methods was fear of the Pap testing finding.

Presence of highly oncogenic human papillomavirus in the oral mucosa of asymptomatic men

ObjectivesThe aim of this study was to identify highly oncogenic forms of human papillomavirus in the oral mucosa of asymptomatic men. MethodsIn this study, we analyzed samples of exfoliated cells from the oral cavity of 559 asymptomatic men. DNA-human papillomavirus was detected using the consensus primers PGMY09/11; viral genotyping was performed using type-specific PCR and restriction fragment length polymorphism. ResultsDNA-human papillomavirus was detected in 1.3% of the study participants and of those 42.8% were infected by more than one type of virus. Viral types included HPV6, 11, 89 (low oncogenic risk), and HPV52, 53 (high oncogenic risk). Increased vulnerability to human papillomavirus infection was observed in individuals aged over 26 years, among those who reported oral sex practices, and in those who have had more than 16 sexual partners since first engaging in sexual intercourse. ConclusionsThere was a low prevalence of human papillomavirus detection in the oral mucosa of asymptomatic men. Highly oncogenic human papillomavirus types and infection by more than one viral type was observed. Oral sex practices and a large number of sexual partners may increase the risk of acquiring human papillomavirus infection.

The role of core groups in the emergence and dissemination of antimicrobial-resistant N gonorrhoeae

Core groups contain individuals who are regularly infected with Neisseria gonorrhoeae and are able to transmit their infection to a large number of sexual partners. Classical core groups, such as...

P4.029 Concurrent Sexual Partnerships in a National Sample of Australian Gay Men

Concurrent sexual partnerships, where individuals have two or more sexual partners at the same time, are major contributors to the transmission of sexually transmitted infections (STIs). Yet, very little is...

Qualitative exploration of HIV-related sexual behaviours and multiple partnerships among Chinese men who have sex with men living in a rural area of Yunnan Province, China

The HIV epidemic has been spreading rapidly among men who have sex with men (MSM) in China. The present study explored the pattern of HIV-related high-risk sexual practices among MSM in a rural Chinese setting. Data were collected by semistructured in-depth interviews conducted among 15 MSM in Yuxi Prefecture, Yunnan Province, China. Fifteen respondents were recruited through a local non-governmental organisation via purposive sampling. Thematic analysis was used. Technological changes, risk behaviours, social stigma and high migration rates have played a significant role in the spread of HIV among MSM in rural China. The Internet has become the primary channel for soliciting casual sex partners in the MSM community. Bisexuality and having concurrent and multiple sexual partners were common among rural MSM. A large number of sexual partners and low condom use in all MSM partnership types were noted. Due to Chinese cultural traditions and social stigma, Chinese rural MSM were reluctant to disclose their homosexuality. Rural-to-urban migrant MSM were often engaged in the commercial sex trade. Rural MSM is a distinctive and complex population with multiple identities in China. Concurrent multiple sexual partnerships, high mobility and low disclosure rate are the major challenges for HIV prevention and intervention programs in MSM.

SEXUAL BEHAVIOR BEFORE MARRIAGE AND CONTRACEPTION CHOICE AMONG FEMALE STUDENTS OF THE CLASSIC UNIVERSITY

We have conducted an anonymous questionnaire of 275 girls-students of the classic university, who reached the age of 20. Main group included 107 smokers, 168 girls of the same age have never smoked tobacco (group of comparison). There is a comparative analysis of sexual behavior before marriage and contraception choice of the girls in both groups. Risky sexual behavior and lower level of contraception culture is typical for smokers: early sexual debut, large number of sexual partners, frequent sexual contacts, irregular using of contraception or giving it up, using of low-effective methods of contraception. Smokers use emergency hormonal contraception 2 times more often. Every 5th girl indicates the presence of sexually transmitted infections in her anamnesis. There is a psychological readiness to induced abortion in smokers.

Alcohol Misuse and Multiple Sexual Partners

IntroductionWe examine the association between self-reported alcohol misuse and alcohol use within 2 hours of having sex and the number of sexual partners among a sample of African-American and Latino emergency department (ED) patients.MethodsCross-sectional data were collected prospectively from a randomized sample of all ED patients during a 5-week period. In face-to-face interviews, subjects were asked to report their alcohol use and number of sexual partners in the past 12 months. Data were analyzed using multiple variable negative binomial regression models, and effect modification was assessed through inclusion of interaction terms.ResultsThe 395 study participants reported an average of 1.4 (standard error = 0.11) sexual partners in the past 12 months, 23% reported misusing alcohol, and 28% reported consuming alcohol before sex. There was no statistically significant association between alcohol misuse and the number of sexual partners; however, alcohol before sex was associated with a larger number of sexual partners in the past year. Moreover, among those who misused alcohol, participants who reported alcohol before sex were 3 times more likely to report a higher number of sexual partners (risk ratio = 3.2; confidence interval [CI] =1.9–5.6). The association between alcohol use before sex and number of sexual partners is dependent upon whether a person has attributes of harmful drinking over the past 12 months. Overall, alcohol use before sex increases the number of sexual partners, but the magnitude of this effect is significantly increased among alcohol misusers.ConclusionAlcohol misusers and those who reported having more than 1 sexual partner were more likely to cluster in the same group, ie, those who used alcohol before sex. Efforts to reduce the burden of sexually transmitted diseases, including human immunodeficiency virus, and other consequences of risky sexual behavior in the ED population should be cognizant of the interplay of alcohol and risky sexual behaviors. EDs should strive to institute a system for regular screening, brief intervention, and referral of at-risk patients to reduce negative consequences of alcohol misuse, including those of risky sexual behaviors.

Differences in the Social Networks of African American Men Who Have Sex With Men Only and Those Who Have Sex With Men and Women

We compared social network characteristics of African American men who have sex with men only (MSMO) with social network characteristics of African American men who have sex with men and women (MSMW). Study participants were 234 African American men who have sex with men who completed a baseline social network assessment for a pilot behavioral HIV prevention intervention in Baltimore, Maryland, from 2006 through 2009. We surveyed the men to elicit the characteristics of their social networks, and we used logistic regression models to assess differences in network characteristics. MSMO were significantly more likely than were MSMW to be HIV-positive (52% vs 31%). We found no differences between MSMO and MSMW in the size of kin networks or emotional and material support networks. MSMW had denser sexual networks, reported more concurrent and exchange partners, used condoms with more sexual partners, and reported interaction with a larger number of sexual partners at least once a week. Although there were many similarities in the social and sexual network characteristics of MSMO and MSMW, differences did exist. HIV prevention interventions should address the unique needs of African American MSMW.