Large-scale Image Datasets Research Articles

An Attention Mechanism-Improved YOLOv7 Object Detection Algorithm for Hemp Duck Count Estimation

Stocking density presents a key factor affecting livestock and poultry production on a large scale as well as animal welfare. However, the current manual counting method used in the hemp duck breeding industry is inefficient, costly in labor, less accurate, and prone to double counting and omission. In this regard, this paper uses deep learning algorithms to achieve real-time monitoring of the number of dense hemp duck flocks and to promote the development of the intelligent farming industry. We constructed a new large-scale hemp duck object detection image dataset, which contains 1500 hemp duck object detection full-body frame labeling and head-only frame labeling. In addition, this paper proposes an improved attention mechanism YOLOv7 algorithm, CBAM-YOLOv7, adding three CBAM modules to the backbone network of YOLOv7 to improve the network’s ability to extract features and introducing SE-YOLOv7 and ECA-YOLOv7 for comparison experiments. The experimental results show that CBAM-YOLOv7 had higher precision, and the recall, mAP@0.5, and mAP@0.5:0.95 were slightly improved. The evaluation index value of CBAM-YOLOv7 improved more than those of SE-YOLOv7 and ECA-YOLOv7. In addition, we also conducted a comparison test between the two labeling methods and found that the head-only labeling method led to the loss of a high volume of feature information, and the full-body frame labeling method demonstrated a better detection effect. The results of the algorithm performance evaluation show that the intelligent hemp duck counting method proposed in this paper is feasible and can promote the development of smart reliable automated duck counting.

Semantic-Rich Facial Emotional Expression Recognition

The ability to perceive human facial emotions is an essential feature of various multi-modal applications, especially in the intelligent human-computer interaction (HCI) area. In recent decades, considerable efforts have been put into researching automatic facial emotion recognition (FER). However, most of the existing FER methods only focus on either basic emotions such as the seven/eight categories (e.g., <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">happiness, anger</i> and <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">surprise</i> ) or abstract dimensions ( <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">valence, arousal, etc.</i> ), while neglecting the fruitful nature of emotion statements. In real-world scenarios, there is definitely a larger vocabulary for describing human's inner feelings as well as their reflection on facial expressions. In this work, we propose to address the semantic richness issue in the FER problem, with an emphasis on the granularity of the emotion concepts. Particularly, we take inspiration from former psycho-linguistic research, which conducted a prototypicality rating study and chose 135 emotion names from hundreds of English emotion terms. Based on the 135 emotion categories, we investigate the corresponding facial expressions by collecting a large-scale 135-class FER image dataset and propose a consequent facial emotion recognition framework. To demonstrate the accessibility of prompting FER research to a fine-grained level, we conduct extensive evaluations on the dataset credibility and the accompanying baseline classification model. The qualitative and quantitative results prove that the problem is meaningful and our solution is effective. To the best of our knowledge, this is the first work aimed at exploiting such a large semantic space for emotion representation in the FER problem.

MFA-net: Object detection for complex X-ray cargo and baggage security imagery.

Deep convolutional networks have been developed to detect prohibited items for automated inspection of X-ray screening systems in the transport security system. To our knowledge, the existing frameworks were developed to recognize threats using only baggage security X-ray scans. Therefore, the detection accuracy in other domains of security X-ray scans, such as cargo X-ray scans, cannot be ensured. We propose an object detection method for efficiently detecting contraband items in both cargo and baggage for X-ray security scans. The proposed network, MFA-net, consists of three plug-and-play modules, including the multiscale dilated convolutional module, fusion feature pyramid network, and auxiliary point detection head. First, the multiscale dilated convolutional module converts the standard convolution of the detector backbone to a conditional convolution by aggregating the features from multiple dilated convolutions using dynamic feature selection to overcome the object-scale variant issue. Second, the fusion feature pyramid network combines the proposed attention and fusion modules to enhance multiscale object recognition and alleviate the object and occlusion problem. Third, the auxiliary point detection head adopts an auxiliary head to predict the new keypoints of the bounding box to emphasize the localizability without requiring further ground-truth information. We tested the performance of the MFA-net on two large-scale X-ray security image datasets from different domains: a Security Inspection X-ray (SIXray) dataset in the baggage domain and our dataset, named CargoX, in the cargo domain. Moreover, MFA-net outperformed state-of-the-art object detectors in both domains. Thus, adopting the proposed modules can further increase the detection capability of the current object detectors on X-ray security images.

A Parallel Teacher for Synthetic-to-Real Domain Adaptation of Traffic Object Detection

Large-scale synthetic traffic image datasets have been widely used to make compensate for the insufficient data in real world. However, the mismatch in domain distribution between synthetic datasets and real datasets hinders the application of the synthetic dataset in the actual vision system of intelligent vehicles. In this paper, we propose a novel synthetic-to-real domain adaptation method to settle the mismatch domain distribution from two aspects, i.e., data level and knowledge level. On the data level, a Style-Content Discriminated Data Recombination (SCD-DR) module is proposed, which decouples the style from content and recombines style and content from different domains to generate a hybrid domain as a transition between synthetic and real domains. On the knowledge level, a novel Iterative Cross-Domain Knowledge Transferring (ICD-KT) module including source knowledge learning, knowledge transferring and knowledge refining is designed, which achieves not only effective domain-invariant feature extraction, but also transfers the knowledge from labeled synthetic images to unlabeled actual images. Comprehensive experiments on public virtual and real dataset pairs demonstrate the effectiveness of our proposed synthetic-to-real domain adaptation approach in object detection of traffic scenes.

Underwater Image Restoration via Contrastive Learning and a Real-World Dataset

Underwater image restoration is of significant importance in unveiling the underwater world. Numerous techniques and algorithms have been developed in recent decades. However, due to fundamental difficulties associated with imaging/sensing, lighting, and refractive geometric distortions in capturing clear underwater images, no comprehensive evaluations have been conducted with regard to underwater image restoration. To address this gap, we constructed a large-scale real underwater image dataset, dubbed Heron Island Coral Reef Dataset (‘HICRD’), for the purpose of benchmarking existing methods and supporting the development of new deep-learning based methods. We employed an accurate water parameter (diffuse attenuation coefficient) to generate the reference images. There are 2000 reference restored images and 6003 original underwater images in the unpaired training set. Furthermore, we present a novel method for underwater image restoration based on an unsupervised image-to-image translation framework. Our proposed method leveraged contrastive learning and generative adversarial networks to maximize the mutual information between raw and restored images. Extensive experiments with comparisons to recent approaches further demonstrate the superiority of our proposed method. Our code and dataset are both publicly available.

Scene Classification Using Deep Networks Combined with Visual Attention

In view of the scene’s complexity and diversity in scene classification, this paper makes full use of the contextual semantic relationships between the objects to describe the visual attention regions of the scenes and combines with the deep convolution neural networks, so that a scene classification model using visual attention and deep networks is constructed. Firstly, the visual attention regions in the scene image are marked by using the context-based saliency detection algorithm. Then, the original image and the visual attention region detection image are superimposed to obtain a visual attention region enhancement image. Furthermore, the deep convolution features of the original image, the visual attention region detection image, and the visual attention region enhancement image are extracted by using the deep convolution neural networks pretrained on the large-scale scene image dataset Places. Finally, the deep visual attention features are constructed by using the multilayer deep convolution features of the deep convolution networks, and a classification model is constructed. In order to verify the effectiveness of the proposed model, the experiments are carried out on four standard scene datasets LabelMe, UIUC-Sports, Scene-15, and MIT67. The results show that the proposed model improves the performance of the classification well and has good adaptability.

Generative adversarial networks (GANs) for image augmentation in agriculture: A systematic review

In agricultural image analysis, optimal model performance is keenly pursued for better fulfilling visual recognition tasks (e.g., image classification, segmentation, object detection and localization), in the presence of challenges with biological variability and unstructured environments. Large-scale, balanced and ground-truthed image datasets are tremendously beneficial but most often difficult to obtain to fuel the development of highly performant models. As artificial intelligence through deep learning is impacting analysis and modeling of agricultural images, image augmentation plays a crucial role in boosting model performance while reducing manual efforts for image collection and labelling, by algorithmically creating and expanding datasets. Beyond traditional data augmentation techniques, generative adversarial network (GAN) invented in 2014 in the computer vision community, provides a suite of novel approaches that can learn good data representations and generate highly realistic samples. Since 2017, there has been a growth of research into GANs for image augmentation or synthesis in agriculture for improved model performance. This paper presents an overview of the evolution of GAN architectures followed by a first systematic review of various applications in agriculture and food systems (https://github.com/Derekabc/GANs-Agriculture), involving a diversity of visual recognition tasks for plant health conditions, weeds, fruits (preharvest), aquaculture, animal farming, plant phenotyping as well as postharvest detection of fruit defects. Challenges and opportunities of GANs are discussed for future research.

SODA: A large-scale open site object detection dataset for deep learning in construction

Comprehensive image datasets can benefit the construction industry in terms of serving as the basis for generating deep-learning-based object detection models and testing the performance of object detection algorithms, but building such datasets is complex and requires vast professional knowledge. This paper develops and publicly releases a new large-scale image dataset specifically collected and annotated for the construction site, called Site Object Detection Dataset (SODA), which contains 15 object classes categorized by the worker, material, machine, and layout. >20,000 images were collected from multiple construction sites in different situations, weather conditions, and construction phases, covering different angles and perspectives. Statistical analysis shows that the dataset is well developed in terms of diversity and volume. Further evaluation with two widely-adopted deep learning-based object detection algorithms also illustrates the feasibility of the dataset, achieving a maximum mAP of 81.47%. This research contributes a large-scale open image dataset for the construction industry and sets up a performance benchmark for further evaluation of relevant algorithms.

DMA‐Net: Dual multi‐instance attention network for X‐ray image classification

Security inspection has been playing a critical role in protecting public space from safety threats. As object detection is a fundamental and mature research filed, it still suffers from numerous challenges such as scale, viewpoint and intra-class variance of X-ray images. The main reasons are, mis-modeling of actual security inspection as well as insufficient effective X-ray samples. To this end, the X-ray inspection task is reconsidered by predicting the dangerous attributes without boxes and categories, a Dual Multi-instance Attention network (DMA-Net) is proposed in this paper to mine the key-instance from both patch and proposal branch. In patch-level multi-instance attention pooling, Recursive Attention Pyramid (RAP) and Spatial-Channel Attention (SCA) are proposed to effectively learn discriminative representation from hierarchical features. Meanwhile, the proposal-level multi-instance attention pooling selectively emphasizes interdependent of crucial regions. The features of dual pooling layers are fused to predict dangerous attributes of X-ray inspection images directly. Further, this paper contributes a large-scale and high-quality X-ray image dataset from railway stations, named Railway Station X-ray (RSXray). Enormous experiments on RSXray, GDXray and SIXray demonstrate that the proposed DMA-Net achieves surprising performance with dual multi instance learning diagrams and attention mechanism. The superiority of the employed framework for applications in real world scenarios are also verified.

Efficient pavement distress classification via deep patch soft selective learning and knowledge distillation

Pavement distress classification is a vital step for automatic pavement inspection and maintenance. Recently, patch-based approaches have achieved promising performances and thus extensive attention in this field. However, these methods simply assume that all patches contribute equally to the distress classification, leading to weakly discriminating abilities of models. Moreover, their tedious processes also lead to low efficiency in inference. The authors present a novel patch-based pavement distress classification approach named Deep Patch Soft Selective Learning, which addresses these issues. Similar to other patch-based approaches, Deep Patch Soft Selective Learning partitions the pavement images into patches and aggregates the patch features to accomplish the task. To address the first issue, a succinct Soft Patch Feature Selection Network is introduced to assess the importance of each patch to the distress classification with a score based on its feature. These scores will be considered as patch-wise weights for feature aggregation. In such a manner, the most discriminative patches are selected in a soft way, and thereby benefit the final classification. To address the inference efficiency issue, knowledge distillation is leveraged to transfer the classification knowledge from Deep Patch Soft Selective Learning to the image-based approaches, such as EfficientNet-B3. This distilled model enables incorporating both the advantages of patch-based approaches in classification performance and the advantages of image-based approaches in inference efficiency. Extensive experiments on a large-scale pavement image dataset named CQU-BPDD demonstrate that Deep Patch Soft Selective Learning outperforms the baselines by a large margin of +7.4% in P@R on the detection task and +3.1% in F1 on the recognition task while enjoying 2.1x throughput of baselines.

Deep Trident Decomposition Network for Single License Plate Image Glare Removal

Deep convolutional neural networks have achieved state-of-the-art performance for the removal of atmospheric obscuration. However, most relevant studies have focused on eliminating the effects of atmospheric obscuration but not on the glare in images caused by reflected sunlight. On the basis of a glare image formation model, we propose a deep trident decomposition network with a large-scale sun glare image dataset for glare removal from single images. Specifically, the proposed network is designed and implemented with a trident decomposition module for decomposing an input glare image into occlusion, foreground, and coarse glare-free images by exploring background features from spatial locations. Moreover, a residual refinement module is adopted to refine the coarse glare-free image into fine glare-free image by learning the residuals from features of multiscale receptive field. The experimental results indicated that the proposed network significantly outperforms state-of-the-art atmospheric obscuration removal networks on the built dataset.

A large-scale image dataset of wood surface defects for automated vision-based quality control processes

The wood industry is facing many challenges. The high variability of raw material and the complexity of manufacturing processes results in a wide range of visible structure defects, whichhave tobe controlled by trained specialists.These manual processes are not only tedious and biased, but also less effective. To overcome the drawbacks of the manual quality control processes, several automated vision-based systems have been proposed. Even though some conducted studies achieved a higher recognition rate than trained experts, researchershave todeal with a lack of large-scale databases and authentic data in this field. To address this issue, we performed a data acquisition experiment set in the industrial environment, where we were able to acquire an extensive set of authentic data from a production line.For this purpose, we designed and implemented a complex technical solution suitable for high-speed acquisition during harsh manufacturing conditions. In this data note, we present a large-scale dataset of high-resolution sawn timber surface imagescontaining more than 43 000 labelledsurface defectsand covering 10 types of the most common wood defects. Moreover, with each image record, we provide two types of labels allowing researchers to perform semantic segmentation, as well as defect classification, and localization.

Agricultural plant cataloging and establishment of a data framework from UAV-based crop images by computer vision.

BackgroundUnmanned aerial vehicle (UAV)–based image retrieval in modern agriculture enables gathering large amounts of spatially referenced crop image data. In large-scale experiments, however, UAV images suffer from containing a multitudinous amount of crops in a complex canopy architecture. Especially for the observation of temporal effects, this complicates the recognition of individual plants over several images and the extraction of relevant information tremendously.ResultsIn this work, we present a hands-on workflow for the automatized temporal and spatial identification and individualization of crop images from UAVs abbreviated as “cataloging” based on comprehensible computer vision methods. We evaluate the workflow on 2 real-world datasets. One dataset is recorded for observation of Cercospora leaf spot—a fungal disease—in sugar beet over an entire growing cycle. The other one deals with harvest prediction of cauliflower plants. The plant catalog is utilized for the extraction of single plant images seen over multiple time points. This gathers a large-scale spatiotemporal image dataset that in turn can be applied to train further machine learning models including various data layers.ConclusionThe presented approach improves analysis and interpretation of UAV data in agriculture significantly. By validation with some reference data, our method shows an accuracy that is similar to more complex deep learning–based recognition techniques. Our workflow is able to automatize plant cataloging and training image extraction, especially for large datasets.

On the multi-level embedding of crypto-image reversible data hiding

Crypto-space reversible image steganography has attracted increasing attention, given its ability to embed authentication information without revealing the image content. This paper presents an efficient reversible data hiding scheme for crypto-images: a block predictor is applied to compute prediction errors, then an adaptive block mapping algorithm is utilized to compress them whose amplitudes are within a small threshold, finally, this strategy can be applied in a multi-level manner to achieve a higher embedding capacity. Due to the correlations among adjacent pixels in the block, images can be sufficiently compressed to reserve abundant space for additional data embedding. Different from the prior arts, the compression code of the image is fully encrypted. Experimental results verify that the embedded data and original image can be perfectly recovered, the security is higher compared with the state-of-the-arts, and a significant improvement in the average embedding rate is achieved on two large-scale image datasets.

Point RCNN: An Angle-Free Framework for Rotated Object Detection

Rotated object detection in aerial images is still challenging due to arbitrary orientations, large scale and aspect ratio variations, and extreme density of objects. Existing state-of-the-art rotated object detection methods mainly rely on angle-based detectors. However, angle-based detectors can easily suffer from a long-standing boundary problem. To tackle this problem, we propose a purely angle-free framework for rotated object detection, called Point RCNN. Point RCNN is a two-stage detector including both PointRPN and PointReg which are angle-free. Given an input aerial image, first, the backbone-FPN extracts hierarchical features, then, the PointRPN module generates an accurate rotated region of interests (RRoIs) by converting the learned representative points of each rotated object using the MinAreaRect function of OpenCV. Motivated by RepPoints, we designed a coarse-to-fine process to regress and refine the representative points for more accurate RRoIs. Next, based on the learned RRoIs of PointRPN, the PointReg module learns to regress and refine the corner points of each RRoI to perform more accurate rotated object detection. Finally, the final rotated bounding box of each rotated object can be attained based on the learned four corner points. In addition, aerial images are often severely unbalanced in categories, and existing rotated object detection methods almost ignore this problem. To tackle the severely unbalanced dataset problem, we propose a balanced dataset strategy. We experimentally verified that re-sampling the images of the rare categories can stabilize the training procedure and further improve the detection performance. Specifically, the performance was improved from 80.37 mAP to 80.71 mAP in DOTA-v1.0. Without unnecessary elaboration, our Point RCNN method achieved new state-of-the-art detection performance on multiple large-scale aerial image datasets, including DOTA-v1.0, DOTA-v1.5, HRSC2016, and UCAS-AOD. Specifically, in DOTA-v1.0, our Point RCNN achieved better detection performance of 80.71 mAP. In DOTA-v1.5, Point RCNN achieved 79.31 mAP, which significantly improved the performance by 2.86 mAP (from ReDet’s 76.45 to our 79.31). In HRSC2016 and UCAS-AOD, our Point RCNN achieved higher performance of 90.53 mAP and 90.04 mAP, respectively.

Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain

The molecular determinants of tissue composition of the human brain remain largely unknown. Recent genome-wide association studies (GWAS) on this topic have had limited success due to methodological constraints. Here, we apply advanced whole-brain analyses on multi-shell diffusion imaging data and multivariate GWAS to two large scale imaging genetic datasets (UK Biobank and the Adolescent Brain Cognitive Development study) to identify and validate genetic association signals. We discover 503 unique genetic loci that have impact on multiple regions of human brain. Among them, more than 79% are validated in either of two large-scale independent imaging datasets. Key molecular pathways involved in axonal growth, astrocyte-mediated neuroinflammation, and synaptogenesis during development are found to significantly impact the measured variations in tissue-specific imaging features. Our results shed new light on the biological determinants of brain tissue composition and their potential overlap with the genetic basis of neuropsychiatric disorders.

Texture Image Recognition Based on Deep Convolutional Neural Network and Transfer Learning

The traditional texture image recognition methods have a complex design process, and the existing methods based on deep learning can’t effectively solve the problem of insufficient texture image samples which lead to unsatisfying recognition accuracy. To solve the above problems, a texture image recognition method based on deep convolutional neural network and transfer learning is proposed. Firstly, a new transfer learning model is constructed by using the deep learning model pretrained on the large-scale ImageNet image dataset. Secondly, the reasonable model super-parameters are set, and the weighted sum of the training loss, the validation loss, and the deep feature distance between the training set and the validation set is taken as the cost function of training process. Finally, the best transfer learning model is determined by layer-by-layer training and validation. The experimental results show that the proposed method achieves 99.76%, 99.87%, 99.80%, 100.00% and 94.01% recognition accuracies on the CUReT, KTH-TIPS, UIUC, UMD and NewBarkTex texture datasets respectively, and has good robustness and recognition ability.

A Deep Learning Approach for the Detection of COVID-19 from Chest X-Ray images using Convolutional Neural Networks

The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread throughout the planet with more than 75.5 million confirmed cases and more than 1.67 million deaths. With limited number of COVID-19 test kits available in medical facilities, it is important to develop and implement an automatic detection system as an alternative diagnosis option for COVID-19 detection that can used on a commercial scale. Chest X-ray is the first imaging technique that plays an important role in the diagnosis of COVID-19 disease. Computer vision and deep learning techniques can help in determining COVID-19 virus with Chest X-ray Images. Due to the high availability of large-scale annotated image datasets, great success has been achieved using convolutional neural network for image analysis and classification. In this research, we have proposed a deep convolutional neural network trained on five open access datasets with binary output: Normal and Covid. The performance of the model is compared with four pre-trained convolutional neural network- based models (COVID-Net, ResNet18, ResNet and MobileNet-V2) and it has been seen that the proposed model provides better accuracy on the validation set as compared to the other four pre-trained models. This research work provides promising results which can be further improvise and implement on a commercial scale.

BTENet: Back-Fat Thickness Estimation Network for Automated Grading of the Korean Commercial Pig

For the automated grading of the Korean commercial pig, we propose deep neural networks called the back-fat thickness estimation network (BTENet). The proposed BTENet contains segmentation and thickness estimation modules to simultaneously perform a back-fat area segmentation and a thickness estimation. The segmentation module estimates a back-fat area mask from an input image. Through both the input image and estimated back-fat mask, the thickness estimation module predicts a real back-fat thickness in millimeters by effectively analyzing the back-fat area. To train BTENet, we also build a large-scale pig image dataset called PigBT. Experimental results validate that the proposed BTENet achieves the reliable thickness estimation (Pearson’s correlation coefficient: 0.915; mean absolute error: 1.275 mm; mean absolute percentage error: 6.4%). Therefore, we expect that BTENet will accelerate a new phase for the automated grading system of the Korean commercial pig.

Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer's disease.

Amyloid-beta deposition is one of the hallmark pathologies in both sporadic Alzheimer’s disease and autosomal-dominant Alzheimer’s disease, the latter of which is caused by mutations in genes involved in amyloid-beta processing. Despite amyloid-beta deposition being a centrepiece to both sporadic Alzheimer’s disease and autosomal-dominant Alzheimer’s disease, some differences between these Alzheimer’s disease subtypes have been observed with respect to the spatial pattern of amyloid-beta. Previous work has shown that the spatial pattern of amyloid-beta in individuals spanning the sporadic Alzheimer’s disease spectrum can be reproduced with high accuracy using an epidemic spreading model which simulates the diffusion of amyloid-beta across neuronal connections and is constrained by individual rates of amyloid-beta production and clearance. However, it has not been investigated whether amyloid-beta deposition in the rarer autosomal-dominant Alzheimer’s disease can be modelled in the same way, and if so, how congruent the spreading patterns of amyloid-beta across sporadic Alzheimer’s disease and autosomal-dominant Alzheimer’s disease are. We leverage the epidemic spreading model as a data-driven approach to probe individual-level variation in the spreading patterns of amyloid-beta across three different large-scale imaging datasets (2 sporadic Alzheimer’s disease, 1 autosomal-dominant Alzheimer’s disease). We applied the epidemic spreading model separately to the Alzheimer’s Disease Neuroimaging initiative (n = 737), the Open Access Series of Imaging Studies (n = 510) and the Dominantly Inherited Alzheimer’s Network (n = 249), the latter two of which were processed using an identical pipeline. We assessed inter- and intra-individual model performance in each dataset separately and further identified the most likely subject-specific epicentre of amyloid-beta spread. Using epicentres defined in previous work in sporadic Alzheimer’s disease, the epidemic spreading model provided moderate prediction of the regional pattern of amyloid-beta deposition across all three datasets. We further find that, whilst the most likely epicentre for most amyloid-beta–positive subjects overlaps with the default mode network, 13% of autosomal-dominant Alzheimer’s disease individuals were best characterized by a striatal origin of amyloid-beta spread. These subjects were also distinguished by being younger than autosomal-dominant Alzheimer’s disease subjects with a default mode network amyloid-beta origin, despite having a similar estimated age of symptom onset. Together, our results suggest that most autosomal-dominant Alzheimer’s disease patients express amyloid-beta spreading patterns similar to those of sporadic Alzheimer’s disease, but that there may be a subset of autosomal-dominant Alzheimer’s disease patients with a separate, striatal phenotype.