The effects of large amplitude and nonsinusoidal motion on pitching airfoil aerodynamics for thrust generation were numerically studied with a 2-D NACA0012 airfoil used, and various 2-D NACA asymmetric airfoils were applied for camber effect study. The large amplitude effect study has been undertaken over a wide range of reduced frequency k (from 6 to 18) and pitching amplitude θ (from 5° to 30°) at Re=1.35×104 with sinusoidal pitching profile used. It is shown that the large pitching amplitude results in much more thrust generated than that at low pitching amplitude and the increase of thrust with amplitude becomes slow when the amplitude reaches some degree. However, the propulsive efficiency noticeably decreases with the increase of θ at a fixed k.An adjustable parameter K was employed to realize various nonsinusoidal motions and the effect of nonsinusoidal motion was investigated with various unsteady parameters (θ, k) applied. The results reveal that nonsinusoidal motion has a noticeable effect on the aerodynamic performance, as it affects the instantaneous force coefficients, maximum thrust coefficients and flow structures. An increase in K results in a better thrust generation performance at fixed θ and k, especially for K>0. It is also shown that the larger K noticeably influences the wake pattern and induces a stronger reverse von Karman vortex street in the wake, which in turn leads to the increased thrust. The camber study was performed on various 2-D NACA airfoils with different cambers and camber locations undergoing sinusoidal pitching motion at θ=5° and Re=1.35×104. It is found that varying camber offers little improvement in thrust generation performance.