Laboratory Experience Research Articles

Unforeseen Connections and New Points of View to Promote Interest and Passion for Earth Sciences

This research is a first result of the initial findings of an ongoing, in-depth inquiry among scientific texts and historical documents, which are revealing surprising discoveries on the fundamental role that Earth sciences have played in shaping historical events, influencing social dynamics, and impacting culture and the arts. This perspective is often overlooked in the conventional understanding of this discipline. This research does not claim to present groundbreaking discoveries or original research but seeks to highlight a totally different aspect of Earth sciences and to present it from a completely original point of view. While it is widely acknowledged that Earth sciences play a crucial role in understanding natural phenomena, global dynamics, and natural risks and hazards; their significant contributions to addressing contemporary challenges such as global warming, extreme weather events, land consumption, and biodiversity loss are less recognized. These issues are vital for environmental protection and sustainable development. Despite this, years of teaching students of all ages, engaging them in practical activities and laboratory experiences across various Earth science fields with the aim to promote knowledge, interest and, when possible, passion for this fascinating discipline, have shown that, if communicated without passion the subject can be perceived as undeniably and inevitably boring-seen merely as a discipline dealing with stones and catastrophes, complex and complicated. This research attempts to offer a new perspective on Earth sciences by providing an effective interpretation of geological phenomena, organizing them according to a logical classification, by typology or by temporal sequence. Natural disasters, such as volcanoes or earthquakes, in some cases well known, instantaneous or longlasting events, are portrayed as unpredictable yet indispensable causes of events that, at first glance, may seem unrelated to Earth sciences but have profoundly influenced human history and culture. This research aims to present a collection of information to educate about 'stones and catastrophes,' demonstrating how Earth sciences, through this unconventional lens, serve as a founding role of various disciplines. They promote the development of skills, both hard and soft, and stimulate curiosity, with the hope of guiding individuals towards a complex yet fascinating discipline."

A comparison of student perspectives on body donation across healthcare professional programs: From prosection- to dissection-based curricula.

Donor-centered education offers students the opportunity to not only acquire visual and tactile experiences for applying anatomical knowledge but also a chance for students to reflect upon fundamental humanistic principles. The exploration of differences in students' viewpoints on body donation and the utilization of body donors in their education remains unexplored across various healthcare professional programs, which has an impact on student learning and experience. This study aimed to qualitatively examine the similarities and differences in student perspectives regarding body donation across three healthcare professional programs. One-page reflections from nursing (n = 37), physical and occupational therapy (n = 49), and medical students (n = 66) regarding their experiences in the anatomy laboratory at McGill University were collected and analyzed using a deductive approach based on themes and sub-themes outlined by Stephens etal. in 2019. Despite differences in their curricula, there were few discrepancies across the programs' reflections suggesting that donor-based learning had similar effects on each user group. Most students across the healthcare professional programs mentioned that their positive laboratory experiences motivated them to donate their bodies, extending the privilege they had to future generations. Nursing students did not reflect upon the notion that working with body donors provided unique learning experiences in the anatomy laboratory. Likewise, physical and occupational therapy (PT/OT) students did not address the importance of maintaining the privacy of body donors by covering certain body parts during lab. These findings show that prosection- and dissection-based exercises encourage reflective practices associated with these of medical ethics, highlighting an important advantage to including donor-based learning in anatomical education.

Binocular rivalry under naturalistic geometry: Evidence from worlds simulated in virtual reality.

Binocular rivalry is a fascinating, widely studied visual phenomenon in which perception alternates between two competing images. This experience, however, is generally restricted to laboratory settings where two irreconcilable images are presented separately to the two eyes, an implausible geometry where two objects occupy the same physical location. Such laboratory experiences are in stark contrast to everyday visual behavior, where rivalry is almost never encountered, casting doubt on whether rivalry is relevant to our understanding of everyday binocular vision. To investigate the external validity of binocular rivalry, we manipulated the geometric plausibility of rival images using a naturalistic, cue-rich, 3D-corridor model created in virtual reality. Rival stimuli were presented in geometrically implausible, semi-plausible, or plausible layouts. Participants tracked rivalry fluctuations in each of these three layouts and for both static and moving rival stimuli. Results revealed significant and canonical binocular rivalry alternations regardless of geometrical plausibility and stimulus type. Rivalry occurred for layouts that mirrored the unnatural geometry used in laboratory studies and for layouts that mimicked real-world occlusion geometry. In a complementary 3D modeling analysis, we show that interocular conflict caused by geometrically plausible occlusion is a common outcome in a visual scene containing multiple objects. Together, our findings demonstrate that binocular rivalry can reliably occur for both geometrically implausible interocular conflicts and conflicts caused by a common form of naturalistic occlusion. Thus, key features of binocular rivalry are not simply laboratory artifacts but generalize to conditions that match the geometry of everyday binocular vision.

Role of research Laboratories in pandemic and epidemic response in the Eastern Mediterranean Region: Experiences from COVID-19, avian influenza, and MERS-CoV.

We share the experience of research laboratories in the Eastern Mediterranean Region (EMR) that contributed to preparedness and response to highly pathogenic avian influenza (HPAI), Middle-East respiratory syndrome coronavirus (MERS-CoV), and coronavirus disease (COVID-19). Research groups in the region were pivotal in identifying, characterizing the pathogens and describing their evolution, distribution, transmission routes, and the immunological profile of exposed populations. They demonstrated the capacity to develop and test antivirals and potential vaccines. The EMR experience is a model of how national systems can work with researchers to improve regional preparedness and response to future epidemics and pandemics.

Verification of the analytical performance of CA 19-9 assay on Abbott Alinity ci®: Experience of the central laboratory Mohammed VI Oujda

Verification of the analytical performance of CA 19-9 assay on Abbott Alinity ci®: Experience of the central laboratory Mohammed VI Oujda

Verification of analytical performance of alpha-fetoprotein assay on the Abbott Alinity ci®: Experience of the central laboratory of Mohammed VI University Hospital of Oujda

The aim of our study was the verification of the analytical performance of alpha-fetoprotein determination on the Abbott CI analyzer utilizing the immuno-chemiluminescence method. The verification process was conducted in the biochemistry laboratory of Mohammed VI University Hospital of Oujda. The working methodology adapted is based on the recommendations of the protocol of the French accreditation committee (COFRAC) accreditation technical guide (GTA) 04, by the evaluation of reproducibility and repeatability. The results obtained by this evaluation were overall satisfactory and have meet the recommended criteria set by supplier and the French society of clinical biology. This study shows that the biochemistry laboratory of Mohammed VI University Hospital of Oujda can deliver an accurate and precise results which can be used for clinical diagnosis and decision making.

Real-world evidence of obinutuzumab and venetoclax in previously treated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma

Venetoclax-obinutuzumab (Ven-O) is frequently administered off-label in relapsed/refractory (r/r) CLL/SLL where venetoclax-rituximab is the approved regimen. We conducted this retrospective, real-world study to evaluate Ven-O in r/r CLL/SLL. Between 7/2019 and 6/2022, 40 patients with r/r CLL/SLL on Ven-O were included. The median age was 72, 28.2% had TP53 mutation and/or 17p deletion, median number of prior therapies was 1 (range, 1–6), and 55% had prior BTK inhibitor exposure. The overall response rate was 90% (complete response [CR] or CR with incomplete marrow recovery in 27.5% and partial response in 62.5%) of patients, and the 2-year progression-free survival was 81.2% (95% CI, 69.5–94.8). Therapy was well tolerated. No laboratory or clinical TLS occurred with venetoclax (Howard criteria). One (3%) patient experienced laboratory TLS with obinutuzumab initiation. In summary, this retrospective cohort study demonstrated that Ven-O achieves frequent, durable responses and can be safely administered in r/r CLL/SLL.

A Novel Approach for Free, Affordable, and Sustainable Microsurgery Laboratory Training for Low- and Middle-Income Countries: University of Wisconsin-Madison Microneurosurgery Laboratory Experience.

In low- and middle-income countries (LMICs), approximately 5 million essential neurosurgical operations per year remain unaddressed. When compared with high-income countries, one of the reasons for this disparity is the lack of microsurgery training laboratories and neurosurgeons trained in microsurgical techniques. In 2020, we founded the Madison Microneurosurgery Initiative to provide no-cost, accessible, and sustainable microsurgery training opportunities to health care professionals from LMICs in their respective countries. We initially focused on enhancing our expertise in microsurgery laboratory training requirements. Subsequently, we procured a wide range of stereo microscopes, light sources, and surgical instrument sets, aiming to develop affordable, high-quality, and long-lasting microsurgery training kits. We then donated those kits to neurosurgeons across LMICs. After successfully delivering the kits to designated locations in LMICs, we have planned to initiate microsurgery laboratory training in these centers by providing a combination of live-streamed, offline, and in-person training assistance in their institutions. We established basic microsurgery laboratory training centers in 28 institutions across 18 LMICs. This was made possible through donations of 57 microsurgery training kits, including 57 stereo microscopes, 2 surgical microscopes, and several advanced surgical instrument sets. Thereafter, we organized 10 live-streamed microanastomosis training sessions in 4 countries: Lebanon, Paraguay, Türkiye, and Bangladesh. Along with distributing the recordings from our live-streamed training sessions with these centers, we also granted them access to our microsurgery training resource library. We thus equipped these institutions with the necessary resources to enable continued learning and hands-on training. Moreover, we organized 7 in-person no-cost hands-on microanastomosis courses in different institutions across Türkiye, Georgia, Azerbaijan, and Paraguay. A total of 113 surgical specialists successfully completed these courses. Our novel approach of providing microsurgery training kits in combination with live-streamed, offline, and in-person training assistance enables sustainable microsurgery laboratory training in LMICs.

An interactive augmented reality framework to enhance the user experience and operational skills in electronics laboratories

Augmented reality (AR) stands as a widely embraced technology that significantly enhances learning experiences for students. AR offers an instructional approach supported by technological design, thereby fostering enriched learning interactions. This research proposes an interactive AR framework, intended to create an augmented reality learning environment (ARLE) for the specific needs of electronics engineering laboratory hardware operations. The ARLE functions as an active learning system designed using a user-centered methodology. It offers interactive 3D models of laboratory equipment, providing learners with preliminary training in equipment operation. The real-time connection between the laboratory apparatus and the AR environment is established using the Arduino board. This interface empowers users to control the AR simulation through the laboratory equipment seamlessly. An experimental study involving 80 engineering students was conducted to evaluate the impact of AR intervention on user experience, usability, and operational skills. The participants were divided into two groups: the experimental group (N = 40) and the control group (N = 40). The experimental group underwent electronics equipment training using ARLE, while the control group followed instructions from a standard instrument handbook. To assess the usability and user experience of ARLE, the system usability scale (SUS) and the user experience questionnaire (UEQ) were employed (N = 40). The findings revealed an SUS score of 80.9 for ARLE, categorizing it as “good” according to SUS ratings. Additionally, the UEQ results demonstrated significantly favorable scores across the six scales when compared to the benchmark dataset. The study's outcomes demonstrate that AR intervention offers learners significant pedagogical value, resulting in a substantial positive impact on operational skills in electronics laboratories.

The Evolving Landscape of Oil and Gas Chemicals: Convergence of Artificial Intelligence and Chemical-Enhanced Oil Recovery in the Energy Transition Toward Sustainable Energy Systems and Net-Zero Emissions

Chemical-enhanced oil recovery (EOR) is a field of study that can gain significantly from artificial intelligence (AI), addressing uncertainties such as mobility control, interfacial tension reduction, wettability alteration, and emulsifications. The primary objective of this paper is to introduce an integrated framework for AI and chemical EOR for energy harvest operations. Central emphasis is placed on the energy transition, with the aim of expediting the development of cleaner energy harvesting systems and attaining the goal of net-zero emission. To do so, we present how the energy transition is changing the manufacturing of the chemicals for EOR application. For this, the uncertainty associated with materials' design and critical role of the simulators for transferring the laboratory experiences into full-field implementations is discussed. The concept of digitalization and its impact on energy companies are highlighted. The role of digital twin in simulators integration is discussed, emphasizing how increased data access can help design more tolerant chemicals for harsh reservoir environments using real-time data. Also, we discuss how the chemical suppliers, research institutes, startups, and field operators can benefit from self-leaning and robotic laboratories for chemicals manufacturing. Moreover, this paper explores how including AI perspectives can improve our understanding of developing chemical formulations by blending hybrid capabilities. This approach contributes to making energy production more sustainable and aligning with the goal of zero emissions. A workflow is presented to demonstrate how the integration of AI and chemical EOR can be used for both hydrocarbon production and other energy transition operations, such as carbon capture, utilization and storage, hydrogen storage, and geothermal reservoirs. The outcome of this paper stands as a pioneering effort that uniquely addresses these challenges for both academia and the industry and can open many additional doors and identify topics requiring further investigations.

Learner experience and motivational beliefs for a VR Lab in advanced undergraduate biology

ABSTRACT Recently, interest in understanding the prospects of virtual environments, specifically virtual reality laboratories (VR Lab) – those that involve a first-person practica experience via a desktop computer or head-mounted display – in science education has increased. Seemingly ingrained in the process of implementing a VR Lab is a supposition of interest, intrinsic motivation, and confidence on the part of participants. These attributes influence the participant’s ability to start and complete the task and support sensemaking and meaningful learning. Thus, this study used expectancy-value theory with the intent of learning experience design to assess the relationship between task value beliefs and those for usability of a VR Lab. Beliefs were also compared to those for physical laboratories, where only a higher cost for the VR Lab was found. Increased cost beliefs suggest that participants perceived the VR Lab as requiring more from them, a negative consequence, which would decrease their potential for seeing it as a viable learning alternative. This finding suggests that a student’s level of content knowledge may influence thier VR Lab experience. Cost belief was significantly related to utility value, giving credence to the theoretical model where cost is a value component. The VR Lab was determined to be marginally usable, but usability was not related to any motivational beliefs.

Determination of chemical composition in Tri-Metal Alloys: a three variable linear equation system approach

To enhance the bridge between macroscopic and symbolic representations in chemistry, we crafted a laboratory module focusing on a three-equation system for chemical composition analysis. Students assess the composition of copper, tin, and aluminum alloys by measuring two properties: density and heat capacity. These non-destructive procedures fit within standard laboratory session durations. After gathering data, students tackle three linear equations linking element mass ratio to alloy composition, density, and heat capacity. By pooling data from various samples, the class achieves a comprehensive understanding. This method aligns with objectives for laboratory education, emphasizing scientific reasoning, practical skills, and subject mastery. Students’ results deviated by +/-10% from actual alloy compositions. The discussion of student-gathered data and results supports the feasibility of the laboratory experience for its implementation in introductory chemistry laboratories.

Stallion sperm concentration measurements: experience and equipment

Accuracy is paramount in evaluating sperm concentration and can be a challenge to those with minimal laboratory experience. Purpose of the study was to determine the effect of operator experience on sperm concentrations using 4 methods: Makler® counting chamber, equine densimeter, iSperm, and NucleoCounter®. There was no difference (p = 0.64) between experienced and novice processors for Makler® counting chamber; was difference (p = 0.005) for equine densimeter; was no difference (p = 0.35) for iSperm; and was tending toward difference (p = 0.068) for NucleoCounter®. Correlation between bias and magnitude for Makler® counting chamber was –0.74 (p = 0.003); for equine densimeter was –0.44 (p = 0.11); for iSperm was 0.06 (p = 0.83), and NucleoCounter® was –0.52 (p = 0.06). Makler® counting chamber produced a mean sperm concentration similar to an experienced processor but had significant variation within novice processors. Equine densimeter significantly overestimated sperm concentrations with novice processors but had the least variation. The iSperm performed poorly for both experienced and novices and produced significantly different concentrations than other methods. Thus, iSperm cannot be recommended to accurately measure sperm concentration. Lastly, NucleoCounter had no difference in mean sperm concentrations or variation and was the best system for a novice processor to gain accurate and repeatable sperm concentration measurements.

Students’ perception of Simulation-based learning in Clinical Skills Lab: A One-year institutional experience at Fazaia Ruth Pfau Medical College

Background: Clinical skills laboratory offers great potential for undergraduate medical education by introducing the students to innovative teaching and learning strategies that efficiently fill the gap between theoretical knowledge and clinical practice. Our study aimed to assess the initial perceptions and experiences of medical students for the newly established clinical skills laboratory at FRPMC. Methods: It was a descriptive cross-sectional study conducted at FRPMC, with 100 medical students of the first-year M.B.B.S. participating in this study. During the academic year, study participants attended six modules from Feb to Dec 2020. A 5-point Likert scale questionnaire was given to each student at the end of the module. Data has been reported as Mean ± SD and an internal consistency evaluation form for each variable was calculated. Results: A total of 100 students participated in the study, 90% of the study participants agreed that their overall skill lab experience of training in the skills lab was satisfactory. 68% of respondents felt that instructors play an important role in organizing and structuring the course material, and 58 to 61% said that the clinical skills training simulates a hospital setting where practicing on real patients would take place. The pre-reading materials and instructions should be provided in advance, according to 64% of students. Conclusion Students’ perceptions and experiences of teaching clinical skills were generally positive. Students showed overall satisfaction over the motivational conducive environment, content taught, gaining confidence, learning procedural skills, and adequacy of the educational equipment for learners in the newly established CSL at FRPMC.

Unhealthy air quality secondary to wildfires is associated with lower blastocyst yield

To study the impact of unhealthy air quality from the 2020 Oregon wildfires on outcomes for patients undergoing invitro fertilization (IVF) treatment. A retrospective cohort study. A university-based fertility clinic. Subjects were undergoing IVF treatment from the 6 weeks preceding the wildfires through a 10-day exposure period. Cohorts were classified on the basis of whether subjects experienced patient and/or laboratory exposure to unhealthy air quality. Patient exposure was defined as at least 4 days of ovarian stimulation overlapping with the exposure, and laboratory exposure was defined as at least 2 days of IVF treatment and embryogenesis overlapping with the exposure. The unexposed cohort consisted of remaining subjects without defined exposure, with cycles in the 6 weeks preceding the wildfires. As some subjects had dual exposure and appeared in both patient and laboratory exposure cohorts, each cohort was separately compared with the unexposed control cohort. A 10-day period of unhealthy air quality caused by smoke plumes from a wildfire event. The primary outcome was the blastulation rate. Secondary outcomes included fertilization rate, number of blastocysts obtained, and cycles with no blastocysts frozen or transferred. Sixty-nine subjects underwent ovarian stimulation and IVF treatment during the 6 weeks preceding the wildfires through the 10-day period of unhealthy air quality. Of these, 15 patients were in the laboratory exposure cohort, 16 were in the patient exposure cohort, and 44 were unexposed. Six subjects appeared in both laboratory and patient exposure cohorts. Although neither exposure cohort had significantly decreased blastulation rate compared with the unexposed, the median number of blastocysts obtained was significantly lower in the laboratory exposure cohort than the unexposed group (2 [range 0-14] vs. 4.5 [range 0-21], respectively). The laboratory exposure cohort had significantly more cycles with no blastocysts obtained (3/15 [20%] vs. 1/44 [2%]). There were no significant differences in IVF treatment outcomes between patient exposure and unexposed cohorts. These findings persisted after controlling for age. There were no significant differences in pregnancy outcomes observed after embryo transfer between the exposure group and the unexposed group. For a cohort of patients undergoing IVF treatment, an acute episode of outside wildfire smoke exposure during fertilization and embryogenesis was associated with decreased blastocyst yield.

Carbon-13 chemical shift tensor measurements for nitrogen-dense compounds.

This paper reports the principal values of the 13 C chemical shift tensors for five nitrogen-dense compounds (i.e., cytosine, uracil, imidazole, guanidine hydrochloride, and aminoguanidine hydrochloride). Although these are all fundamentally important compounds, the majority do not have 13 C chemical shift tensors reported in the literature. The chemical shift tensors are obtained from 1 H→13 C cross-polarization magic-angle spinning (CP/MAS) experiments that were conducted at a high field of 18.8T to suppress the effects of 14 N-13 C residual dipolar coupling. Quantum chemical calculations using density functional theory are used to obtain the 13 C magnetic shielding tensors for these compounds. The best agreement with experiment arises from calculations using the hybrid functional PBE0 or the double-hybrid functional PBE0-DH, along with the triple-zeta basis sets TZ2P or pc-3, respectively, and intermolecular effects modeled using large clusters of molecules with electrostatic embedding through the COSMO approach. These measurements are part of an ongoing effort to expand the catalog of accurate 13 C chemical shift tensor measurements, with the aim of creating a database that may be useful for benchmarking the accuracy of quantum chemical calculations, developing nuclear magnetic resonance (NMR) crystallography protocols, or aiding in applications involving machine learning or data mining. This work was conducted at the National High Magnetic Field Laboratory as part of a 2-week school for introducing undergraduate students to practical laboratory experience that will prepare them for scientific careers or postgraduate studies.

DC Microgrid for Robotic Manufacturing – field demonstration and laboratory experience.

Paper present real manufacturing application based approach to DC based power supply and infrastructure verification. Alternative solutions for improved management of power flows and integration of renewable energy sources has become an interesting topic and discussions of alternative DC related power infrastructure with respect to existing technology. Since modern manufacturing solutions implement industrial robot manipulators more detailed evaluation of possible opportunities regarding DC based supply has been introduced. Typical distribution of units and respective electrical power flows present need for power measurement equipment with multipoint functionality experiments. Obtained practical measurement results enable evaluation of DC based energy distribution system potential compared to existing solution and future operation scenarios including energy storage and buffering approaches. Implementation of single AC/DC converter unit has been evaluated in laboratory conditions with respect to power quality within DC distribution link.

Biosafety Management Based Upon Risk Assessment and Monitoring: Perspectives from a Clinical Laboratory, China.

Inadequate risk assessment and a lack of risk monitoring are common deficiencies in clinical laboratory, and are also the main causes of biosafety incidents. Therefore, we summarized the experience of implementing adequate risk assessment and maintaining risk monitoring, and established a procedure for continuously improving biosafety management. Learning from our laboratory's experience in implementing risk assessment, risk response, and risk monitoring before and during the COVID-19 epidemic, we summarized the procedures for fully identifying risks, accurately evaluating risks, maintaining risk monitoring, establishing and regular reviewing safety indicators. On this basis, we established a system for continuously improving biosafety management through risk monitoring and reviewing safety indicator. We identified a total of 30 unacceptable risks prior to the COVID-19 pandemic, and developed and implemented appropriate risk control measures. After risk control, residual risks were acceptable, and no biosafety incidents have occurred. During the COVID-19 pandemic, after multiple risk monitoring, we identified ten new risks, three ineffective risk control measures, and multiple control measures for excessive protection. Then, we timely adjusted risk control measures to avoid laboratory personnel infection and excessive protection. Meanwhile, We established eight safety indicators and identified two improvement opportunities through regular reviews. Adequate risk identification and accurate risk assessment are particularly important for effectively controlling biosafety risks. Biosafety management should be continuously improved to deal with ineffective and excessive protection caused by various changes in experimental activities. Continuous improvement of biosafety management can be achieved through risk monitoring, regular review of safety indicators, and management reviews. This study will help laboratory managers to fully and accurately assess risks, as well as update risks and their control measures through risk monitoring, and the continuous improvement procedure established in the study has certain reference value for laboratories to effectively respond to emerging infectious diseases and avoid excessive protection.

Prenatal Testing for Variants in Genes Associated with Hereditary Cancer Risk: Laboratory Experience and Considerations

Prenatal molecular genetic testing for familial variants that cause inherited disorders has been performed for decades and is accepted as standard of care. However, the spectrum of genes considered for prenatal testing is expanding due to genetic testing for hereditary cancer risk (HCR) and inclusion of conditions with associated cancer risk in carrier screening panels. A few of these disorders, such as ataxia telangiectasia and Bloom syndrome, include increased cancer risk as part of the phenotype, already meet professional guidelines for prenatal testing, and may be associated with increased cancer risk in heterozygous carriers. Additionally, recent studies implicate heterozygosity for variants in lysosomal storage disease (LSD) genes in HCR etiology. Currently, there is no specific professional guidance regarding prenatal testing for HCR. In order to determine the prevalence of such testing we reviewed 1345 consecutive prenatal specimens received in our laboratory for familial variant specific testing and identified 65 (4.8%) with a known or likely HCR component, plus 210 (15.6%) for LSD. These specimens were classified into five distinct categories for clarity and to enable evaluation. Our experience assessing prenatal specimens for variants associated with HCR, with or without a constitutional phenotype, provides metrics for and contributes to the points to consider in prenatal testing for HCR.

ФОРМИРОВАНИЕ ПРЕДПРИНИМАТЕЛЬСКОЙ ИНИЦИАТИВЫ В СФЕРЕ КРЕАТИВНЫХ ИНДУСТРИЙ У ЛЮДЕЙ С ИНВАЛИДНОСТЬЮ И ОВЗ

The development of social entrepreneurship in the field of creative industries is today an urgent task of social policy and economy of our country. The article presents the experience of inclusive creative laboratories in creating conditions for the formation of entrepreneurial initiatives in the creative industries among people with disabilities and limited health capabilities.