treatment for end-stage knee OA, with approximately 500,000 procedures performed each year in the United States. Several studies have examined the long-term effects of TKA on the biomechanics of the operated knee and have found that most patient still demonstrate poor gait patterns that are similar to their gait patterns preoperatively. In the frontal plane, researchers have found that KAM is improved at 6 months after surgery, but slowly regresses back to higher, preoperative levels after 1 year. In the long-term, KAM is not significantly different from preoperative levels. This finding is noteworthy since high KAM may result in prosthetic degradation and failure in the long term. There is a lack of information on the biomechanical postoperative results of surgery in the period earlier than six months. The purpose of the present study was to determine if gait patterns of the knee in the frontal plane are improved in the early postoperative period. This would help determine what, if any, changes can be made to therapy protocols to prevent regression to preoperative gait levels with time. Furthermore, outcomes were examined across different knee prosthetics to determine if differences exist between prosthetic types. Methods: Fifty patients were examined before and two months after TKA. Patients underwent a 3D gait analysis using the Vicon Motion Analysis system (Oxford Metrics Ltd., Oxford, UK). Patients completed a VAS scale for pain and functional tests. Knee prosthetics included either PCL-retaining or PCL sacrificing, and custom fit design or not. Results: Peak knee varus angle during gait showed a significant reduction and improvement of 3.1 postoperatively (p1⁄40.001) (Figure 1). After surgery, first and second peak KAM decreased to 71% and 77% of preoperative values (Figure 2), respectively (both p1⁄40.001), and knee adduction impulse decreased by 30% postoperatively (p<0.001) (Table 1) and VAS pain scores decreased by 21% (p<0.001). Spatiotemporal parameters and functional tests did not yet show significant improvements by two months. No significant differences were found between outcomes in patients undergoing PCL retaining TKA or PCL sacrificing TKA, or between patients undergoing custom fit TKA and those not. Changes were consistent across BMI, age, gender and pain scores. Conclusions: TKA results in high improvement in kinematic and kinetic parameters in the frontal plane early in postoperative recovery. The results also suggest that there is an absence of differences between types of knee prostheses. When compared to the findings of previous studies, the results suggest that early after surgery, TKA patients will show decreased, improved KAM, but these improvements are slowly lost over the first and second year postoperatively. This highlights the importance of early intervention postoperatively aimed at maintaining the low levels of KAM and joint loading. This may help reduce the risk of prosthetic failure and surgical revision in the long-term. 146 CAUSAL LINK BETWEEN PEAK KNEE ADDUCTION MOMENT DURING WALKING AND STRUCTURAL PROGRESSION OF KNEE OSTEOARTHRITIS: A SYSTEMATIC REVIEW OF COHORTS AND RANDOMIZED TRIALS M. Henriksen , M. Creaby , H. Lund , C. Juhl , R. Christensen . y The Parker Inst., Copenhagen, Denmark; Ctr. of Physical Activity Across the Lifespan, Sch. of Exercise Sci., Australian Catholic Univ., Brisbane, Australia; x Inst. of Sports Sci. and Clinical Biomechanics, Univ. of Southern Denmark, Odense, Denmark
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