<i>Purpose </i>In the face of the problems in medical equipment quality control, such as manpower shortage, lack of standardization, insufficient quality control equipment and weak information means, the implementation methods of medical equipment quality control are improved effectively by reorganizing the key points of quality control and introducing the overall maintenance service of medical equipment. <i>Methods</i> On the basis of researching and determining the quality control objects of medical equipment, formulating the work content of medical equipment quality control and supporting special quality control record sheets, formulating the work plan of medical equipment quality control, and adjusting the quality control content in time according to the actual clinical needs, our hospital has passed and the overall maintenance company of medical equipment cooperates closely and obtains the support of manpower, quality control equipment and information management tools to ensure that the quality control of medical equipment is in place. <i>Result </i>Through the standardization of medical equipment quality control, the efficiency of medical equipment quality control has been significantly improved, and the operation quality failure rate of quality control objects has decreased year by year, and we can find the hidden trouble of medical equipment operation quality and solve it accordingly. In addition, compared with hospital engineers, there is a certain gap in the medical equipment quality control ability of maintenance engineers in medical equipment overall maintenance service companies. At the same time, there are still some shortcomings in the coverage of quality control work. <i>Conclusion</i> Overall medical equipment maintenance service is conducive to the implementation of medical equipment quality control, and quality control is effective in improving the operation quality of medical equipment, and can guarantee the safety of medical service, but there is still a large space for improvement.