In a fast developing field of molecular pathology, it is difficult to find up to date molecular diagnostics without considerable searching and literature review. This single-volume edition consisting of nine, well-indexed sections, including molecular pathology of solid and haematological tumours, is a treasure. The expanding knowledge of molecular oncology as a result of next-generation sequencing technology has enabled recent developments in drugable targets and changes in diagnostics. Often questions are asked of pathologists by clinical colleagues into further molecular diagnostics. Having information to hand that is well referenced and helpful both for diagnosis and treatment planning, which is easy to access and interpret, is incredibly important. The sections are colour coordinated, allowing quick browsing of sections. The central nervous system tumours are in the solid tumour sections, coded green; this is easy to find even with the book sitting on the table. This ease of navigation is very useful as I find myself constantly dipping into different sections, so the colour coding is most helpful. Central nervous system tumours are covered in section 8 from pages 8-382 to 8-416, including sections of Glial Tumours, subdivided into High-Grade and Low-Grade Tumours, Pilocytic Astrocytoma and Oligodedroglioma. There are separate sections of Ependymoma, Medulloblastoma, Choroid Plexus Tumours, Meningioma and Retinoblastoma. Also, there are other sections covering lymphoid tumours and of course, the solid tumours that metastasise to the CNS. The chapters include clear histopathological pictures including relevant immunohistochemical stains. The text is written in easy to follow bullet points which are subdivided into sections including clinical, radiological and macroscopic findings as well as histological and, of course, molecular sections. There is a large subsection including the molecular changes with different tumour subtypes, which again are bullet points and split up in molecular subtypes including those with particular clinical relevance. For those looking for an even quicker reference, there are ‘Key Fact’ boxes for all tumour subtypes which provide clinical, histopathological and molecular ‘highlights’ at a glance and are truly excellent summaries, and very useful for exam revision. The expert consult access is as ever, an absolute triumph of modern technology. To be able to carry a searchable edition of the book on your smart phone or tablet means that you are never without the answer. The histological pictures alone are high-definition images that zoom well on electronic devices with high-definition screens and are excellent for showing vital diagnostic features. The text is easy to search and accessible for instant information. One criticism of this is that you do require a high-speed Internet link for the search function, and a downloadable PDF would be useful for those times you cannot access the Internet, such as when in most hospitals in the UK. I would not let that put me off, however. There are very few molecular pathology books, if any, to compare this to, that provide the same amount of detail with such good correlates. The main advantage of the book is it saves sifting through the published literature and brings it together in an easy to follow single volume, which is a distinct advantage as you do not keep picking the wrong volume from the shelf. At a fraction under £200 this is a very well-referenced book, which provides a good bench-side reference for molecular pathology. The major advantage of this book to me is the correlation with the other available findings seen clinically, radiologically and histologically. I highly recommend this book for surgical pathologist as well as those with an interest in molecular pathology and research. For consultants and registrars this provides a good summary in one place to aid our day to day work. It also provides useful high-volume facts which are ideal for exam revision.