In this paper two dimensional models of airfoils (NACA0012, NACA2412) are analyzed for the aerodynamic characteristics at various Reynolds numbers for a range of angles of attack from low lift through stall, based on the chord length of the airfoil. The local characteristics, the lift, drag, pressure coefficients are simulated by using three models the Spalart-Allmaras, the k-epsilon (RNG) and the k-omega shear stress transport (SST). The comparison of predictions and experimental measurements in the wind tunnel of the National Aeronautics Advisory Committee (NACA) for selected aerodynamic airfoils are presented. The blade geometric parameters including chord and twist angle distributions are determined based on aerodynamic parameters results at a specific Reynolds number. This study is carried out by providing an optimal blade design strategy for horizontal-axis wind turbines operating at different Reynolds numbers. As a conclusion the simulation results were compared with the experimental results. In general, good concordances were noted. This approach can be further developed to create the most efficient of horizontal axis wind turbine blade design.