The Pnar, commonly known as Jaintia, is a sub-tribe of the Khasi community in Meghalaya. They are indigenous to the East and West Jaintia Hills District of Meghalaya. In this study, indigenous use of medicinal plants by the Pnar community has been reported. The field survey was conducted from December 2019 to July 2020 and data were obtained using open-ended semi-structured questionnaires and field observation with traditional healers and local inhabitants of the community. A total of 40 medicinal plants belonging to 22 families were collected and documented. These plant species are widely used by the local communities in ten villages of East Jaintia Hills District for the treatment of different ailments. As observed from the results, Asteraceae, Euphorbiaceae, and Zingiberaceae are the most prominent families among the identified species. Moreover, the report incorporates the mode of administration and dosage of these herbal medications.