Control in multi-agent decision-making systems is an important issue with a wide variety of existing approaches. In this work, we offer a new comprehensive framework for distributed control. The main contributions of this paper are summarized as follows. First, we propose PHIMEC (physics-informed meta control)—an architecture for learning optimal control by employing a physics-informed neural network when the state space is too large for reward-based learning. Second, we offer a way to leverage impulse response as a tool for system modeling and control. We propose IMPULSTM, a novel approach for incorporating time awareness into recurrent neural networks designed to accommodate irregular sampling rates in the signal. Third, we propose DIMAS, a modular approach to increasing computational efficiency in distributed control systems via domain-knowledge integration. We analyze the performance of the first two contributions on a set of corresponding benchmarks and then showcase their combined performance as a domain-informed distributed control system. The proposed approaches show satisfactory performance both individually in their respective applications and as a connected system.