Intestinal Infections In Children Research Articles

ABSTRACT 670

Background and aims: Among the infectious agents of acute intestinal infections in children such anaerobic microorganisms as C.perfringents, C.sordelli, C.difficile play a significant role. The studied on development of the methods for identification of Clostridii difficile. Aims: The purpose of our job was study the clinical-laboratory characteristic features of the acute intestinal infections in children of young age. Methods: We have studied 32 children at the age from 4 months to 3 years. In 86.2% of cases the children were hospitalized at the first week of disease that allowed to perform examinations at early time of disease. We used polymerase chain reaction (PCR) for identification toxin Clostridia difficile in diarrhea. Toxin Clostridia difficile was found from feces of the children with salmonellosis – in 30%, dysentery – in 10%, staphylococcus diarrhea – 20% and intestinal infections of unknown etiology – in 30% of cases. Results: Analysis of clinical data we revealed generalizations of infectious processes in 70% of patients as well as sepsis development. All patients had acute onset of the disease with higher temperature (70.1%), appearance of frequent stool to 10–20 times a day. Evaluation of the severity of diseases showed prevalence of the severe form (61.1%). Symptoms of intoxication were marked sharply. Hepatomegaly was noted in 46.2% and splenomegaly in 25.3% of children. In 15% of patients there was found myocardium damage (carditis). The hospital staying was 27.1 ± 2.1 days. Conclusions: The data obtained showed that diarrheal diseases produced by anaerobic microorganisms may be considered as serious problem which require special approach to the aspects of diagnosis and appropriate complex treatment.

Актуальные вопросы острых кишечных инфекций в последние годы

Цель: изучение клинико-эпидемиологических особенностей острых кишечных инфекций у детей Донецкой области.Материал и методы. Работа выполнена на академической базе детских инфекционных отделений Донецкой области и Донецкого областного лабораторного центра Госсанэпидслужбы Украины. Сравнительный анализ этиологически установленных острых кишечных инфекций у детей проведен за период 1996–2012 гг.

Применение фекального маркера «кальпротектин» в диагностике кишечных инфекций у детей

Применение фекального маркера «кальпротектин» в диагностике кишечных инфекций у детей

Sequential diet therapy of acute intestinal infections in children

Sequential diet therapy of acute intestinal infections in children

ROTAVIRUS INFECTION. HOW TO REALLY PROTECT CHILDREN FROM SEVERE GASTROENTERITIS?

научный биометрический журнал, который знакомит читателя с клиническими рекомендациями и особенностями применения лекарственных и вакцинных средств у детей, предоставляет исчерпывающую информацию о воздействии лекарственных средств на плод, о проводимых в

Clinical And Factorial Analysis Of Pathological States In Acute Intestinal Infections In Children

The author reported clinical characteristic features and risk factors for acute intestinal infections in 225 children (140 boys and 85 girls, mean age 1.5 years old). 90 (40%) patients aged up to 12 months, 101 (44.9%) were from 1 to 2 years old, and 34 (15.1%) were more than 2 years old. Most children were hospitalized in the first week of illness and had moderate severe course of disease. Severe forms of illness reliably more often were noted in children being on artificial feeding. Toxic-dystrophic condition, severe forms and perinatal encephalopathy were prevailed in boys. Factorial analysis revealed 20 most significant factors with factorization fullness 70.8%. The most significant factors were F-1(factor of hyperthermia duration) with 8.5% effect, F-2 (factor of pain syndrome) – 5.8%, F-3 (factor of normal enzymatic activity of colon bacillus) – 4.9%, F-4 (etiological factor) – 4.6%, as well as F-5(factor of opportunistic flora of the intestine) – 4.4%, respectively.

Epidemiological characteristics of viral diarrhea in children of Uzbekistan

With the purpose of an estimation of the contribution of virus agents in the etiological structure of acute intestinal infections in children during the rise of prevalence of acute intestinal infections from 2009 to 2011 there were studied 1050 children admitted to the hospital with diarrheal diseases. It is established, that acute intestinal infections have a viral nature in 56.67% of cases. T hus the leading role belongs to rotaviruses and adenoviruses. Infectious agents of diarrheal diseases are rotaviruses in 28.1 % of cases, adenoviruses $ in 105 %, and astroviruses $ in 11. 43 %. The viral monoinfections occur more often, than mixed$infections. The rise of sporadic diseases of viral diarrhea was characterized by seasonal prevalence. For intestinal infections of viral etiology the seasonal rise in a cold season with peak of the rate of diseases of rotavirus infection in April, adenoviral inf ection in November, and astrovirus infection in December is characteristic.

Current aspects of epidemiology, clinic and diagnosis of campylobacteriosis

The problem of campylobacteriosis (CB) has been widely covered in the national and foreign literature over the past 10-20 years. Probably, the interest to this topic is due to a number of reasons. From a microbiological point of view, the causative agent of CB was discovered relatively recently and is an actively studied microorganism. At the same time, the responsibility of the microbe for the development of diseases in domestic animals and birds brings it into the category of problems of veterinary pathology. In medical terms, CB, taking into account modern epidemiological studies, is attributed to the group of the most common bacterial intestinal infections in children of different age groups, since it causes from 5 to 44.9% of all cases of the disease.

Disturbed fat absorption following infectious gastroenteritis in children

Fat absorption was studied in 10 patients recovering from an episode of acute infectious gastroenteritis who failed to gain weight despite adequate caloric intake. Three patients restudied after clinical improvement and three other infants with failure to thrive, unrelated to gastrointestinal problems, served as control subjects. Fat balance studies during the ingestion of a formula containing long-chain fatty acids demonstrated significant degrees of steatorrhea in patients (mean CFA 70.6 +/- 10.7 compared to 90.3 +/- 2.4 in control subjects). The administration of a test meal demonstrated a marked deficiency of duodenal bile acid concentration and of fat incorporation into the micellar phase in patients. Fecal bile acid excretion was significantly increased in patients (mean 33.9 +/- 11.6 microM/kg/day) as compared to control subjects (mean 13.5 +/- 3.1 microM/kg/day). Bacterial overgrowth and abnormalities of the small intestinal mucosa were not constant. Ileal dysfunction and associated bile acid loss are possible causes of disturbed fat assimilation following acute intestinal infection in children.