Background Gender diverse people with a chronic illness and/or disability (CI/D) encounter stigma and disempowerment at all social-ecological levels, reducing access to individual health promoting behaviors and resulting in population health disparities. Living at the intersection of two populations experiencing social marginalization, this group is also at higher risk of experiencing chronic stress—a factor that leads to suboptimal health outcomes over the life span. Aims To better understand the experiences of individuals embodying this intersection of identity and experience, and to learn more about promoting health within this population, qualitative interviews were conducted. Methods Fifteen gender diverse people who live with a CI/D acquired in adulthood took part in in-depth, semi-structured narrative interviews about life stressors and experiences related to their intersecting identities. Data were analyzed using inductive thematic analysis. Results Participants described social isolation and mental health struggles as significant challenges. Support from communities of shared identity mediated stress and bolstered mental health, but participants reported few opportunities to make such connections. Consistent with existing literature, these results highlight the significant role social safety plays in health and well-being. Conclusion This work emphasizes the critical role of applying intersectional frameworks to health promotion in gender diverse communities. The findings can be leveraged by psychologists, community health workers, and other professionals to support this population.
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