PurposeEntrepreneurs belonging to ethnic minority groups have emerged as a significant and more powerful element within the private sector, having considerable economic and social impact. Nevertheless, prior empirical research has indicated that each geographical area has distinct social and cultural obstacles that impact entrepreneurs in varying ways. Hence, the purpose of this study is to examine the difficulties and barriers faced by women entrepreneurs from diverse ethnic origins in the United Kingdom, a developed region, while managing their firms.Design/methodology/approachIn this research, the cross-concepts of intersectional theory were used as the study’s analytical framework. The research methodology involved conducting semi-structured face-to-face interviews with a group of 30 Nepali women entrepreneurs residing in the United Kingdom. A qualitative approach was employed, and thematic analysis was used to extract meaningful findings.FindingsThe study’s outcomes underscore the emergence of social stereotypes as a salient factor affecting Nepali female entrepreneurs. Furthermore, the research identifies challenges and barriers, which fall into several cross-concept categories: those related to self-efficacy; family; social and cultural factors; business-related issues; access to financial resources; and ethnicity and work-based categorization. The findings might also have broader implications, benefiting ethnic female entrepreneurs in general, as well as ethnic communities and governmental and non-governmental organizations. Insights gained from the study can inform the development of tailored training and educational programs aimed at supporting and nurturing the entrepreneurial aspirations of ethnic women.Originality/valueTo the best of the researchers’ knowledge, there is a dearth of empirical investigations that probe the challenges and barriers faced by Nepali women who have embarked on entrepreneurial endeavours in the UK. This study contributes to the limited literature knowledge on ethnic women entrepreneurs, by linking ethnicity, class and gender/sexual orientation, as well as business, family, personal and financial constructs. By adopting the cross-concept of intersectional theory, this study further contributes to the knowledge of the discriminatory realities of Nepali women entrepreneurs as they grapple with the complex experiences of running a business. By doing this, our study can contribute further to the knowledge of gender and entrepreneurship from the ethnic background of UK enterprises.