This study aims to analyze the determinant factors of Counterproductive Work Behavior (CWB) to make plan strategies for overcoming Counterproductive Work Behavior. This research used the Interpretative Structural Modeling (ISM) method. The ISM method is able to show the interrelationships between existing elements. This method can be developed to plan strategic human resource management policies related to CWB. The strategy for managing human resources related to CWB in automotive companies in Bekasi is carried out according to the level of importance based on a problem. The results showed that it is necessary to overcome Counterproductive Work Behavior by handling job stress (Task demands, Role demands, Family problems, and Economic problems) and role ambiguity (Clarity of Responsibilities, Clarity of goals, and Clarity of roles and scope of work).