International Organization For Standardization Research Articles

Internet of Things, critical infrastructures, and the governance of cybersecurity in 5G network slicing

Over the last decade, cybersecurity has become a disruptive challenge driven by the shift to 5G networks. 5G is an application-agnostic general-purpose technology (GPT) characterized by its major role as multidimensional upstream technology for a large and open set of downstream Internet of Things (IoT) applications and use cases in various network industries and, more generally, within the economy as a whole. The focus of this paper is on the network economics of cybersecurity governance, considering the interplay between the recent EU cybersecurity regulatory framework, the extensive standardization efforts of international standardization organizations, and the economic incentives to tackle 5G network performance and security challenges. Based on the economic concept of 5G-based network slicing, the entrepreneurial challenges driven by the Internet of Things (IoT) are analyzed with an eye towards the complementarity between the physical side and virtual side of IoT applications. Network slicing gains particular relevance in the context of different types of logically separated, QoS-differentiated 5G bandwidth capacities, which are combined with other virtual resources such as sensor networks, data storage and processing, together with end-to-end slice security. It is shown in this paper that economic incentives for the implementation of 5G cybersecurity cannot be considered in isolation but must be viewed in combination with other performance requirements of 5G network slices. This is the driver for implementing network slicing architectures within 5G networks that feature a multitude of heterogeneous network slices with different QoS differentiation and various cybersecurity requirements.

Assuring fire safety in nuclear plants with international standards

This paper presents the evolution and benefits of international standards for fire safety engineering11Fire safety engineering and performance-based fire safety are both widely used, and both represent an engineering process to determine performance of a fire protection plan based on the results of fire calculations. developed at the International Organization of Standardization (ISO). The history of fire safety in nuclear power plants along with the need for fire safety regulation is discussed to lay the foundation for the standards development work. The evolution of fire safety regulation from prescriptive to performance-based is also presented as the background for the research.Extensive research of the issues that arise for performance-based fire safety regulation, specifically for computer models for fire safety calculations, which included international benchmark exercises formed the basis to identify the need for developing international standards for fire safety engineering. The research focused both on the verification and validation (V&V) of computer fire models and determining their predictive capability. The paper for the first time takes new scientific and engineering data from benchmark exercises to assess the suitability and applicability of computer fire models for application in nuclear power plants. The paper reports on the findings of the benchmark exercises and their use in formulating new requirements in ISO international standards on verification and validation of fire calculation methods and the fire safety engineering process through a consensus process of international experts.Discussion of the foundational research at the ISO fire safety engineering committee (ISO TC 92 SC 4) led to a consensus to revise two international standards. One specifying the principles and general requirements for fire safety engineering, and another on the verification and validation procedures for fire calculation methods. The development and content of these two international standards are discussed in this paper. An international technical report was subsequently developed at the ISO committee for conformity assessment (CASCO) to provide guidance for the certification of the fire safety engineering process, and specific parts of it, namely the V&V of fire calculation methods.It is concluded that the fire safety engineering international standards presented in this paper can support rigorous performance-based fire safety regulation for nuclear power plants. These ISO international standards will be particularly useful to nations that have not yet developed the regulatory infrastructure for nuclear power regulation. The international standards are also available to those that would like to transition to the use of international standards and an ISO standards-based certification scheme. Regulations based on these international standards will provide citizens with confidence in nuclear power as a viable option to address climate change.

Sampling targets to assess occupational health in occupational health and safety management system audits: a mixed-methods research in Japan.

Occupational health and safety management systems (OHSMS) are the foundation of occupational health and safety activities within an organization. An important element of these systems is audits. However, OHSMS auditors often lack confidence in conducting occupational health audits compared with their proficiency in conducting occupational safety audits. For occupational health to be effectively managed by OHSMS, the sampling competence of auditors engaged in third-party audits should be improved. Therefore, we conducted this study to identify appropriate sampling targets for occupational health related to International Organization for Standardization (ISO) 45001. We adopted a mixed methods approach to identify appropriate sampling targets. This involved conducting focus group discussions with experts in occupational health and performing systematic text condensation analysis. The validity of our findings was further reinforced through confirmation by external auditors who specialize in ISO 45001. In the qualitative phase, 6 occupational health sampling targets were identified, and of these, 5 were subsequently validated in the quantitative phase: (1) Health issues, legal requirements, and occupational health goals identified by the organization; (2) Occupational health risk assessment and control processes; (3) Processes related to occupational health and documented information showing the results of efforts; (4) Organizational roles and functions of occupational health professionals and opportunities for their professional development; and (5) Processes to ensure commitment to occupational health issues and objectives. To ensure effective and comprehensive occupational health audits, auditors should review these targets. This study will enhance the competence of auditors by identifying appropriate occupational health sampling targets.

Implementing data exchange and interoperability on LADM country profiles using the ISO framework for enterprise interoperability standard

For a complete, harmonized and modernized land administration processes, seamless data exchange among departments within an organization, and among organizations is a fundamental requirement. Interoperability is therefore crucial and should be based on a well-developed Land Administration Domain Model (LADM) country profile for the implementation of a Land Administration System (LAS). This paper, through a research synthesis type of literature review methodology, looks into the existing documentation on interoperability in Land Administration (LA). Employing research synthesis method, analysis of the identified and existing resources is done. Since interoperability plays a role at multiple levels, it is paramount to apply a solid framework such as the Framework for Enterprise Interoperability (FEI) developed by International Standards Organization (ISO). This allows for the investigation of the critical aspects of data exchange: (i) business, processes, services and data, (ii) interoperability barriers: conceptual, technological and organizational, and (iii) interoperability approaches: federated, unified and integrated. The paper looks into the interoperability concerns and barriers and the approaches to addressing them for Land Administration against the elements of FEI. This provides an effective guideline for implementation of a LADM-based land administration system for any country.

Establishment of a Reference Material in Quality Control for Use in Infectivity and Identity Assays of Recombinant COVID-19 Vaccine, in Accordance with International Standards Organization Guidance.

The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), began in 2019. One of the strategies for pandemic control was mass vaccination. In Brazil, the recombinant COVID-19 vaccine (RCV) was produced on a large scale and offered at no charge to the population. The specifications for quality control analyses of RCV included identity and infectivity determination. To validate the results, a reference material (RM) must be analyzed in parallel with the sample vaccine. This research aimed to establish the RM for use in the identity and infectivity assay for RCV. The candidate RM was analyzed using homogeneity and stability studies. The RM was considered homogeneous for identity (cycle threshold (Ct) ≤ 25.19) and infectivity (average x- was 9.25 log10 infectious units/mL). The RM was considered adequately stable for identity during the total period in all studies, being stable at -70, 5, and 22.5 °C for 380, 313, and 14 days, respectively (Ct ≤ 21.81). For infectivity, the RM was stable at -70, 5, and 22.5 °C for 380, 97, and three days, respectively. Since the property identity and infectivity values of the RM were established, the new RM could be used in quality control analysis.

Evaluation of several routine methods for fosfomycin and mecillinam susceptibility testing of Enterobacterales urine isolates.

Performance evaluation of routine laboratory methods to determine the susceptibility of Enterobacterales urinary isolates to fosfomycin (oral administration) and mecillinam. We collected 347 Enterobacterales isolates from monomicrobial midstream urine samples from women with significant bacteriuria and leukocyturia. Mostly non-Escherichia coli isolates (i.e. Klebsiella spp., Citrobacter koseri, Enterobacter cloacae complex and Proteus mirabilis) were included (n = 298). Performance of VITEK®2, ETEST®, and disc diffusion to determine fosfomycin and mecillinam susceptibility was evaluated following International Organization for Standardization (ISO) 20776-2:2021 (or 20776-2:2007 for disc diffusion) in comparison with the agar dilution reference method. For fosfomycin testing, VITEK®2 and ETEST® were close to reaching ISO requirements (essential agreement ≥ 90%; bias ±30%) for C. koseri, E. coli and P. mirabilis. Categorical agreement (CA) and major error rates were acceptable for disc diffusion. Fosfomycin displayed lower activity against E. cloacae complex and Klebsiella spp., with MIC50 (minimum inhibitory concentration required to inhibit the growth of 50% of tested isolates) equal to the E. coli EUCAST breakpoint (8 mg/L). For these species, the three alternative techniques overestimated MICs and resistance, and did not meet performance criteria. For mecillinam testing of Enterobacterales isolates, apart from P. mirabilis, ETEST® nearly fulfilled ISO requirements, and CA rates were acceptable for disc diffusion. ISO criteria were reached for C. koseri and E. coli testing with VITEK®2, apart from too high rates of very major errors. For P. mirabilis, performances were unacceptable, whatever the routine method used. Commercially available tests may serve as alternatives to agar dilution to assess fosfomycin (oral) and mecillinam susceptibility of Enterobacterales urinary isolates, with important interspecies variabilities. Additional studies comprising more fosfomycin- and mecillinam-resistant isolates are needed to strengthen our conclusions.

The hidden concept and the beauty of multiple “R” in the framework of waste strategies development reflecting to circular economy principles

There are numerous unresolved research questions, along with ongoing debates, regarding how to achieve a circular economy and at what level. The forthcoming circular economy standard (ISO 59000 framework, ISO59010) as a result from the ISO/TC 323, from the International Organization for Standardization (ISO) aims to offer global implementation pathways using a unified technical language. The most challenging aspect of circularity, whether viewed scientifically, technically, and/or legislatively, is how to enhance prosperity while reducing reliance on primary materials and energy to achieve climate neutrality by 2050, thereby aiding the EU in achieving a successful and equitable transition towards a sustainable future. Strategies in the framework of waste management and circular economy are essential and needed to reduce the impact of several processes on the environment through product, processes, and corporate policies using green applicable sustainable resources and environmental management systems. In addition, “measuring something that is not there” is very complex and not fully comprehensible, not clear and not tangible from organizations, researchers, policy makers and citizens. The willingness and ability of individuals or organizations to take actions towards a low-carbon society involves grappling with various perspectives, such as social norms and economic viability. Circular economy is considered a tool in combating climate change and implementing climate mitigation (as well as adaptation) measures. Moreover, to date, there has been no common scientific or technical language for the application of the circular economy concept. This paper highlights the multitude of “Rs” beyond the well-known (3Rs) Reduce-Reuse-Recycle pattern, which can be applied in various contexts to assist SMEs (Small and Medium Enterprises), organizations and even citizens successfully adopt circular economy principles. Is also explores how these “Rs” can be utilized to measure intangible aspects (something that is not there). The results indicate that more than 55Rs exist which directly involved in the circular economy framework, also considering waste management strategies. The findings of this study reveal the existence of over 100 “Rs” beyond the well-known principles of “reduce, reuse, recycle,” each playing a distinct role in the development of strategies aimed at addressing waste management issues and advancing circularity towards a low-carbon society. Furthermore, the results could be useful for any policy makers, consultants, engineers, practitioners, urban planners, academics etc., in order to develop, apply, monitor, measure and improve any strategy such as circular economy strategy, waste prevention, zero waste, reuse, reduce, energy recovery etc., in the framework of circular economy principles, solid waste management and beyond.

Diagnostic Performances of an in-House Immunochromatography Test Based on the Monoclonal Antibody 18B7 to Glucuronoxylomannan for Clinical Suspected Cryptococcosis: a Large-Scale Prototype Evaluation in Northern Thailand.

Cryptococcosis predominantly presents as a meningoencephalitis in Thailand. Early and expeditious diagnosis is essential for reducing both mortality and morbidity associated with cryptococcal meningitis. We aim to define and establish the diagnostic performances between the benchmark commercially available diagnostic kit (CrAg® LFA) and the large-scale prototype of an inexpensive in-house immunochromatographic test (ICT) based on monoclonal antibody (MAb) 18B7. We have developed the large-scale prototype for the rapid detection of cryptococcal polysaccharide antigens by utilizing a single antibody sandwich ICT format employing MAb 18B7, which is highly specific to Cryptococcus neoformans glucuronoxylomannan (GXM) antigens. An in-house MAb18B7 ICT was manufactured in accordance with industry standards under the control of the International Organization for Standardization (ISO) 13485. The diagnostic sensitivity, specificity, and accuracy for the in-house MAb 18B7 ICT were 99.10%, 97.61%, and 97.83%, respectively. The agreement kappa (κ) coefficient was 0.968 based on the retrospective evaluation of 580 specimens from patients living in northern Thailand with clinically suspected cryptococcosis. The data suggest that this in-house MAb 18B7 ICT will be highly beneficial for addressing the issue of cryptococcal infection in Thailand. Moreover, it is anticipated that this inexpensive ICT can play a pivotal role in various global strategies aimed at eradicating cryptococcal meningitis among individuals living with HIV by 2030.

Самоконтроль уровня глюкозы у пациентов с сахарным диабетом 2-го типа

Self-monitoring of blood glucose has been considered to be a cornerstone of adequate diabetes management for decades. The structured self-monitoring leads to better compensation of carbohydrate metabolism disorders, decreased risk of hypoglycemia, and quality of life improvement in patients with DM. The technologies, as well as the glucose meter convenience and accuracy have improved considerably since the moment these were introduced several decades ago. Modern glucose meters are small and easy to use; these require small amounts of capillary blood and provide measurement results within seconds. Furthermore, glucose meters are more and more often equipped with such features, as connectivity with other devices and/or electronic diaries and instruments for diabetes management. Despite the fact that the measurement accuracy can be close to or equal to the quality level ensured by laboratory biochemical analyzers, some glucose meters continue to fall short of the internationally accepted accuracy standards, such as ISO-15197, the standard of the International Organization for Standardization. Numerous reports from the number of countries, such as Russia, China, India, and Brazil, that are based on the routine practice data suggest that in addition to the problems with the glucose meter accuracy, there are other obstacles to overcome to optimize the use of blood glucose monitoring systems. Nevertheless, the adequate use of blood glucose self-monitoring data is very important for treatment of patients with type 2 diabetes mellitus.

Contactless and Calibration-Free Blood Pressure and Pulse Rate Monitor for Screening and Monitoring of Hypertension: Cross-Sectional Validation Study.

The key to reducing the immense morbidity and mortality burdens of cardiovascular diseases is to help people keep their blood pressure (BP) at safe levels. This requires that more people with hypertension be identified, diagnosed, and given tools to lower their BP. BP monitors are critical to hypertension diagnosis and management. However, there are characteristics of conventional BP monitors (oscillometric cuff sphygmomanometers) that hinder rapid and effective hypertension diagnosis and management. Calibration-free, software-only BP monitors that operate on ubiquitous mobile devices can enable on-demand BP monitoring, overcoming the hardware barriers of conventional BP monitors. This study aims to investigate the accuracy of a contactless BP monitor software app for classifying the full range of clinically relevant BPs as hypertensive or nonhypertensive and to evaluate its accuracy for measuring the pulse rate (PR) and BP of people with BPs relevant to stage-1 hypertension. The software app, known commercially as Lifelight, was investigated following the data collection and data analysis methodology outlined in International Organization for Standardization (ISO) 81060-2:2018/AMD 1:2020 "Non-invasive Sphygmomanometers-Part 2: Clinical investigation of automated measurement type." This validation study was conducted by the independent laboratory Element Materials Technology Boulder (formerly Clinimark). The study generated data from 85 people aged 18-85 years with a wide-ranging distribution of BPs specified in ISO 81060-2:2018/AMD 1:2020. At least 20% were required to have Fitzpatrick scale skin tones of 5 or 6 (ie, dark skin tones). The accuracy of the app's BP measurements was assessed by comparing its BP measurements with measurements made by dual-observer manual auscultation using the same-arm sequential method specified in ISO 81060-2:2018/AMD 1:2020. The accuracy of the app's PR measurements was assessed by comparing its measurements with concurrent electroencephalography-derived heart rate values. The app measured PR with an accuracy root-mean-square of 1.3 beats per minute and mean absolute error of 1.1 (SD 0.8) beats per minute. The sensitivity and specificity with which it determined that BPs exceeded the in-clinic systolic threshold for hypertension diagnosis were 70.1% and 71.7%, respectively. These rates are consistent with those reported for conventional BP monitors in a literature review by The National Institute for Health and Care Excellence. The app's mean error for measuring BP in the range of normotension and stage-1 hypertension (ie, 65/85, 76% of participants) was 6.5 (SD 12.9) mm Hg for systolic BP and 0.4 (SD 10.6) mm Hg for diastolic BP. Mean absolute error was 11.3 (SD 10.0) mm Hg and 8.6 (SD 6.8) mm Hg, respectively. A calibration-free, software-only medical device was independently tested against ISO 81060-2:2018/AMD 1:2020. The safety and performance demonstrated in this study suggest that this technique could be a potential solution for rapid and scalable screening and management of hypertension.

Land Cover and Land Use Ontology—Evolution of International Standards, Challenges, and Opportunities

Knowledge of land is of central importance to manage the impact of mankind upon the environment. The understanding and treatment of land vary greatly across different regions and communities, making the description of land highly specific to each locality. To address the larger global issues, such as world food production or climate change mitigation, one needs to have a common standardized understanding of the biosphere cover and use of land. Different governments and institutions established national systems to describe thematic content of land within their jurisdictions. These systems are all valid and tuned to address various national needs. However, their integration at regional or global levels is lacking. Integrating data from widely divergent sources to create world datasets not only requires standards, but also an approach to integrate national and regional land cover classification systems. The ISO 19144 series, developed through the collaboration between the Food and Agriculture Organization of the United Nations (FAO) and the International Organization for Standardization (ISO), offers a meta-language for the integration of disparate land classification systems, enhancing interoperability, data sharing, and national to global data integration and comparison. This paper provides an overview of classification system concepts, different stages for the development of standards in ISO and the status of different standards in the ISO 19144 series. It also explores the critical role of the ISO 19144 series in standardizing land cover and land use classification systems. Drawing on practical case studies, the paper underscores the series’ potential to support global sustainable development goals and lays out a path for its future development and application. Using these standards, we gain not only a tool for harmonizing land classification, but also a critical level for advancing sustainable development and environmental stewardship worldwide.

Are we approaching the development of a novel calcium phosphate-based bioceramic dental material?

ObjectivesDevelop a sustainable bovine hydroxyapatite dental ceramic with the addition of titanium dioxide (TiO2) nanoparticles (5 % and 8 % by weight), analyzing the outcome of this addition to the microstructure, as well as its mechanical and chemical properties, in order to evaluate whether they satisfy the International Organization for Standardization (ISO) 6872:2015 for dental ceramics or not. MethodsDisks were obtained through uniaxial followed by isostatic pressing from bovine hydroxyapatite powder and TiO2 nanoparticles and sintered at 1300ºC for 2 h. Three experimental groups were developed (HA, HA+5 %TiO2 and HA+8 %TiO2) and subjected to X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), indentation fracture (IF), biaxial flexural strength (BFS) and chemical solubility test. ResultsXRD revealed, for HA group, the appearance of a peak corresponding to b-tricalcium phosphate (ß-TCP). For HA+ 5 %TiO2 and HA+ 8 %TiO2, the entire composition was converted into ß-TCP and calcium titanate (CaTiO3). The SEM images showed a dense ceramic matrix and a uniform distribution of another phase in groups with TiO2 nanoparticles. HA+ 5 %TiO2 (1.40 ± 0.18 MPa.m1/2) and HA+ 8 %TiO2 (1.32 ± 0.18 MPa.m1/2) showed significantly higher fracture toughness values than HA (0.67 ± 0.09 MPa.m1/2). HA showed significantly higher characteristic stress (295.8 MPa) in comparison to groups with 5 % (235.1 MPa) and 8 % (214.4 MPa) TiO2 nanoparticles. Differences were not observed between the Weibull modulus values. The solubility results indicated that all experimental ceramics were above the 2000 ug/cm2 limit set by the ISO 6872:2015. SignificanceThis study proposed the development and characterization of a new ceramic for dental prosthesis made from HA extracted from bovine bones, with the intention of reusing these solids waste and transforming them into a sustainable and low-cost material. Although the experimental calcium phosphate ceramic with additions of 5 % and 8 % of TiO2 achieved desirable mechanical properties, the chemical solubility values were very high.

Readiness for sustainable accreditation management in higher education institutions: A mixed-method study in Indonesia

Obtaining an excellent accreditation rank in various study programs has become an urgency for universities in Indonesia because accreditation rankings are believed to have an impact on the provision of quality education. However, not all universities are able to achieve an excellent accreditation rank for all of the study programs they manage. This research aims to determine the readiness of the accreditation teams in managing accreditation in various study programs. The mixed method is used, with an explanatory sequential design. The participants involved are university leaders and accreditation teams in various study programs. The research results showed that an excellent accreditation rating cannot be achieved with ordinary organizational behavior but requires great effort, care, and commitment from both the leaders and the accreditation team. It also requires active and comprehensive participation from the academic community. The excellent rank in accreditation can only be obtained with superior effort and care. It is suggested that the readiness of the leaders and accreditation teams to manage accreditation optimally is a crucial aspect in achieving an excellent rating. In conclusion, there are at least three important aspects to consider in the accreditation process in order to achieve an excellent rank: the need to achieve the highest assessment, the effort and care needed to significantly impact the highest assessment, and the institution needs to ensure a quality culture through quality assurance and the International Organization for Standardization (ISO).

Understanding the Standard for Tele-Services as Part of Hearing Aid Fitting Management

Recently, the International Organization for Standardization (ISO) published ISO 21388-2, which focuses on tele-services as part of hearing aid fitting management (tHAFM). This report introduces the fundamental aspects of ISO 21388-2 for tele-services in hearing aid fitting to assist in the proper adoption and utilization of tHAFM services in South Korea. The primary goal of tHAFM is to achieve the highest rehabilitation outcomes for hearing aid users, equivalent to those of traditional face-to-face services. It specifies the precondition requirements and general frameworks for tele-service delivery. As there is still a lack of reporting on the provision of tele-services related to hearing aid fitting in South Korea, future research should focus more on providing and validating the effectiveness of tele-services for domestic hearing aid users. Additionally, there is a need to establish step-by-step guidelines and professional education programs based on the ISO 21388-2 standard for the utilization of tHAFM. It is expected that the ISO 21388-2 standard will serve as a fundamental guideline for hearing aid professionals in effectively providing tele-services to achieve these goals.

Measurement of Glycemic Index: A High-Protein Peptide-Based Enteral Formula

Hyperglycemia among hospitalized patients is associated with an increased risk of mortality and infectious complications. In critically ill patients, hyperglycemia often occurs as a physiological response to stress. For critically ill patients who require nutrition support but have severe malabsorption or intolerance to polymeric formulas, oligomeric formulas may be beneficial. However, hyperglycemia might be a concern with these oligomeric formulas. This study aimed to determine the glycemic index (GI) of a test food, TOP-OP13NPD, a high-protein peptide-based enteral formula. The GI value of TOP-OP13NPD was determined following the protocols outlined in the International Organization for Standardization 26642:2010, involving 10 healthy adults (with an equal proportion of males and females). Both the reference glucose and test food provided 50 g of carbohydrates, and participants’ blood glucose levels were monitored for two hours. After consuming TOP-OP13NPD at 15, 30, 45, and 60 minutes, subjects exhibited significantly lower blood glucose levels than those on the glucose reference diet (p < 0.001). The incremental area under the curve at 120 minutes was also significantly lower compared to the glucose reference diet (1,380.08 ± 276.48 and 3,082.59 ± 677.16 mg × min/dL; p < 0.01). The mean ± SEM GI value of the test food was 48.62 ± 5.86. TOP-OP13NPD is classified as a low glycemic index diet. This result suggests that this formula may be suitable for individuals requiring oligomeric enteral nutrition who need to control their blood glucose levels.

Burst pressure performance comparison of type V hydrogen tanks: Evaluating various shapes and materials

Hydrogen, as a clean energy carrier, presents a significant step toward sustainable energy solutions but faces challenges in storage due to its low energy density and high volatility. This study addresses the optimization of Type V hydrogen storage tanks by investigating the burst pressure performance of spherical, cylindrical, and toroidal shapes. Using finite element analysis (FEA) and first-order shear deformation theory, we examined how these geometries impact burst pressure outcomes across a range of composite materials and layup configurations. The materials tested included carbon T700/epoxy, Kevlar/epoxy, E-glass fiber/epoxy, and basalt/epoxy. Results demonstrate that the toroidal shape significantly outperforms spherical and cylindrical designs in stress distribution and burst pressure, with basalt/epoxy composites exhibiting superior burst pressure performance (12.7 MPa) compared to Kevlar/epoxy (10.8 MPa), E-glass fiber/epoxy (11.4 MPa), and carbon T700/epoxy (8.9 MPa). Kevlar/epoxy toroidal tanks outperform other materials in weight performance, having a structural performance index of 0.0305 Mpa.m3/kg and hydrogen density per unit mass of 0.0251 kg H2/kg. The stacking sequence [-45/45]s optimized stress distribution for the toroidal shape across all materials. The findings highlight that toroidal designs offer significant advantages for high-pressure hydrogen storage, providing efficient stress management and improved safety. This paper underlines the potential of toroidal vessels for enhancing hydrogen storage efficiency and emphasizes the importance of material selection and stacking sequences in achieving optimal burst pressure performance for international organization for standardization (ISO) certification.

Validating the accuracy of the Omron HBP-M4500 blood pressure measuring device according to the ISO81060-2:2018+ Amd 1:2020 protocol.

Blood pressure (BP) naturally undergoes fluctuations and variations, particularly during anesthesia administration during surgery, hemodialysis, upper and lower gastrointestinal endoscopy, exercise testing, arterial and venous catheterization, and rehabilitation. These changes in BP may lead to life-threatening events. The performance of the Omron HBP-M4500 device in monitoring blood pressure (BP) in the upper arm was validated according to the International Organization for Standardization (ISO) 81060-2:2018+amendment (Amd) 1:2020 protocol. The device was used to assess 113 participants in the inflation mode, and 107 participants in the deflation mode. All the patients fulfilled the inclusion criteria, including the arm circumference range and systolic and diastolic BP levels, outlined in the protocol. Data validation and analysis were performed according to the manufacturer's instructions. In criterion 1, the mean ± standard deviation (SD) values of the differences between the test device and reference BP were -0.6 ± 5.80/2.8 ± 6.78 mmHg (systolic/diastolic) and -1.0 ± 5.35/3.2 ± 6.52 mmHg for the inflation and deflation modes, respectively. These data fulfilled the ISO81060-2:2018+Amd1:2020 requirements of ⩽ 5 ±⁣⩽ 8 mmHg. In criterion 2, the differences were -0.6 ± 4.44/2.8 ± 6.26 and -1.0 ± 3.84/3.2 ± 6.09 mmHg for the inflation and deflation modes, respectively, fulfilling criterion 2 with SD values of ⩽ 6.91 and ⩽ 6.87 for systolic BP and ⩽ 6.34 and ⩽ 6.14 for diastolic BP in the inflation and deflation modes, respectively. These two criteria were fulfilled in both studies. The Omron HBP-M4500 device, either in inflation or deflation mode, fulfilled the criteria outlined in the ISO protocol. Therefore, this device is valuable for BP measurement in clinical and hospital settings.

Perceptions of Students at Andalas University's Payakumbuh Campus Regarding the Security of Academic Information Systems

Higher Education is one of the public service providers that wants to provide the best service to internal and external parties who need information, namely by utilizing academic information systems. The use of academic information systems is prone to data and information crimes, which are problems experienced by many system users and this also occurs in Indonesia. The method in this study uses a qualitative description method in this study and data collection is obtained using triangulation techniques. The results of the study, that it is necessary to improve information security from various threats, thus ensuring the security of valuable information assets. Information security using The International Organization for Standardization (ISO)/IEC 27001. In addition, it is also necessary to perform two-factor authentication which adds a two-step verification process to access the account.

Measurement of inward leakage of full-face masks in EN and ISO standards: comparison of gas and aerosol test agents.

In Europe, respiratory protective devices must be certified before they can be marketed. Among the parameters of interest, inward leakage (IL) characterizes the tightness between the face seal and the face, to verify that the device is well-designed. European standard EN 13274-1 (2001) and International Organization for Standardization (ISO) standard ISO 16900-1 (2019) specify that IL should be measured using sodium chloride (NaCl) aerosol or sulfur hexafluoride (SF6) gas. For reusable masks made of nonporous materials, both test agents are considered equally acceptable. However, the few studies that have compared IL values measured with various aerosols and gases have come to divergent conclusions. This work then aimed to measure IL with the test agents recommended by the standards to determine whether they are really equivalent. Since krypton (Kr) is an interesting candidate for replacing SF6 in standard tests, IL was assessed with SF6 and Kr simultaneously, and with NaCl aerosol using various calculation methods. Tests were carried out on 5 models of full-face masks donned on a headform connected to a breathing machine simulating 3 sinusoidal breathing rates of various intensities. The respirator fit on the headform was evaluated using a controlled negative pressure method to determine a manikin fit factor. Four scenarios were then tested to represent very poor, bad, good, and excellent fit. Gas concentration was measured using a mass spectrometer, and IL was calculated for SF6 and Kr. A combination of 3 devices allowed the determination of the number-based concentration of particles with diameters between 20 nm and 2 µm, and IL was calculated for each of the 33 channels, as well as using a cumulative number concentration. In addition, to comply with standards, a conversion was carried out to calculate IL using a cumulative mass concentration. The results of this work evidenced that the IL values measured with NaCl were systematically lower than those determined with gases. IL was also shown to vary with particle size, with a maximum value exceeding that calculated with cumulative concentrations (in number or mass). As part of the revision of the standards, protocols for measuring inward leakage should be redefined. On the one hand, acceptability thresholds should be re-evaluated according to the nature of the test agent (gas or aerosol), as it is clear that the 2 options do not give the same results for a given configuration. On the other hand, the aerosol leakage measurement protocol needs to be reworked to enable the measurement of a well-defined, robust, and reproducible inward leakage value.

Development of a New Method for Evaluating Heat and Moisture Exchanger Performance.

A model system described in International Organization for Standardization 9360 is the standard method for estimating the humidifying performance of heat and moisture exchangers (HMEs). However, there are no reliable bedside methods for evaluating the ongoing humidification performance of HMEs. Therefore, this study aimed to develop 2 clinically applicable methods for estimating the ongoing humidifying performance of HMEs and to evaluate their reliability in a model system. Physiologically expired gas was simulated using a heated humidifier, and ventilation was delivered using a ventilator with constant flow through 3 different types of HMEs. Relative humidity (RH) was measured using a capacitive-type moisture sensor. Water content lost during expiration was calculated by integrating absolute humidity (AH), instantaneous gas flow measured at the expiratory outlet of the ventilator, and time. We also calculated the water content released and captured by the HMEs during tidal ventilation by integrating the difference in AH across the HMEs, instantaneous gas flow, and time. We found that the RH, temperature, and AH were almost constant on the expiratory outlet of the ventilator but rapidly varied near the HMEs. The water content lost by the 3 HMEs was associated with the manufacturer-reported values and inversely correlated with the calculated values of the water content exchanged by the HMEs. The water content released and captured by HMEs was closely correlated with the difference in HME weight measured at the end of inspiration and expiration; however, the water content captured by HMEs seemed to be overestimated. Our results demonstrated that our system was able to detect the differences in the performance of 3 models of HMEs and suggest that our method for calculating water loss is reliable for estimating the water retention performance of HMEs during mechanical ventilation, even in the presence of a constant flow.