Abstract
Hyperglycemia among hospitalized patients is associated with an increased risk of mortality and infectious complications. In critically ill patients, hyperglycemia often occurs as a physiological response to stress. For critically ill patients who require nutrition support but have severe malabsorption or intolerance to polymeric formulas, oligomeric formulas may be beneficial. However, hyperglycemia might be a concern with these oligomeric formulas. This study aimed to determine the glycemic index (GI) of a test food, TOP-OP13NPD, a high-protein peptide-based enteral formula. The GI value of TOP-OP13NPD was determined following the protocols outlined in the International Organization for Standardization 26642:2010, involving 10 healthy adults (with an equal proportion of males and females). Both the reference glucose and test food provided 50 g of carbohydrates, and participants’ blood glucose levels were monitored for two hours. After consuming TOP-OP13NPD at 15, 30, 45, and 60 minutes, subjects exhibited significantly lower blood glucose levels than those on the glucose reference diet (p < 0.001). The incremental area under the curve at 120 minutes was also significantly lower compared to the glucose reference diet (1,380.08 ± 276.48 and 3,082.59 ± 677.16 mg × min/dL; p < 0.01). The mean ± SEM GI value of the test food was 48.62 ± 5.86. TOP-OP13NPD is classified as a low glycemic index diet. This result suggests that this formula may be suitable for individuals requiring oligomeric enteral nutrition who need to control their blood glucose levels.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.