Forest monitoring programs have become widespread in Amazon Basin countries. Using GPS artifacts, smartphones, drones, and other technologies, international environmental non-government organizations (IENGOs) propose these programs as tools to control and stop deforestation events—and thus of climate change mitigation. These also seem like ideal initiatives for IENGOs to collaborate with Indigenous organizations, responding to calls to include their knowledge in climate governance. I analyze forest/territorial monitoring programs created by the Coordinator of Indigenous Organizations of the Amazon Basin (COICA) and its member organizations in Ecuador and Peru. Scholarship in Science and Technology Studies (STS) and digital geographies has demonstrated how digital environmental technologies and environmental relations and politics can co-produce and shape one another. It has also referred to the historically exploitative relationships that technoscientific projects have enforced towards Indigenous peoples, and the potential of digital tools for emancipatory goals. I argue that forest monitoring programs and technologies co-produce forms of climate and territorial politics in Amazonia. Through forest monitoring programs, Indigenous leaders and organizations imagine and enact territorial defense, or a politics founded on integral territorial ontologies. That is, they see the programs as tools to strengthen their autonomy, to build the capacities of leaders at all scales of political organization, and to support their claims for territorial rights. For them, technologies can make Indigenous cosmovisions or ancestral knowledges visible. However, these programs can also reinforce a politics (of IENGOs) where territories are spaces with strict boundaries and exclusive rights, and which encourages open-access information, thus potentially threatening Indigenous autonomy. Thus, I discuss the intrinsically contradictory impact of monitoring technologies, as the conceptions of territories as lifeworlds, and the embeddedness of ancestral knowledges in them, further exceed their possibilities. Conclusions highlight the importance of attending to Indigenous territorial defense to understand how (new) technologies and society shape each other, and the many implications of climate change responses to justice issues.