The article considers topical issues of development of clusters of ecological diplomacy in the context of international cooperation. The author determines the need to form a new mechanism of economic development, taking into account the policy of ecological security, changes in the format of negotiations, diversification of ecological and economic activity, and institutional potential. The deterioration of the environment and resource support is of concern to humanity, which requires the creation of economic and global rules of interaction between countries. The ecological factor affects the transformation of international economic relations, competitive relations, market advantages, the potential of countries and their ability to develop cooperation on the basis of cluster formations. The current approaches to multilateral ecological diplomacy have been systematized. It is proposed to consider clusters of ecological diplomacy according to the following principles: multilateralism, interaction and interconnectedness of spheres of activity. It is proved that the role of clusters of ecological diplomacy will grow, and their functioning will contribute to: ecological and economic cooperation of diplomatic missions of different countries; exchange of experience between diplomats on new models of contacts in the sphere of ecologization of international economic activity. Applying the system principle to clustering covers topical issues in solving global problems. The development of ecological diplomacy in Ukraine is a promising direction, but so far it is accompanied by the lack of an integrated approach to the mechanisms of its implementation at the ideological, political, legislative, institutional and organizational levels. Ecological diplomacy is the direction of systemic and integrated diplomatic activity when generating a new level of representation and protection of ecological and economic interests of countries and other subjects of international cooperation, oriented to progressive mechanisms for transforming global challenges into qualitatively new opportunities for balanced development and ecological security of society