Internal Origin Research Articles

Mining Risks at Exploitation in Roşia Poieni Open Pit Mine, Romania

Abstract The mining sector is a particularly important field that has the ability to support the economic development of a country by supplying various mineral products that are used as raw materials in other sectors of activity. When the depth at which a deposit is located and the geological conditions allow, the exploitation of useful mineral substances is realized through open-pit mine. The aim of this paper is to analyze the malfunctions that could occur and cause susceptible incidents and that could have consequences on staff safety and the environment. These malfunctions can have different causes: either an internal origin of the mining unit, or in natural phenomena. In this paper are identified and analyzed the potential mining risks that may occur in the Roşia Poieni open pit mine. The guidelines underlying the identification of these risks took into account three main principles: reducing risks for people, ensuring their security and at the same time limiting the risks on the property, respectively the financial risk for the mining unit. Acknowledge these risks, allows the delimitation of areas that are directly or indirectly exposed to potential risks and the establishment of specific measures for prevention, protection and security regarding the realized activities. Depending on the potential mining risks identified, we have made a hazard map that can be used to develop a risk prevention plan, taking into account the presence of several types of risks that may overlap in the same work area of the quarry.

Концепции «nation-building» Ф. Фукуямы и Р. Купера и их значение для современной практики нациестроительства

The process of nation-building in modern societies within the framework of national integration is considered in the article from different approaches and taking into consideration analysis and understanding of foreign experience. Special attention is paid to the concepts and views of Francis Fukuyama and Robert Cooper along with their importance for practice of nation-building. An inference is made that today these concepts and attempts to implement them in practice cannot be recognized as perfect and adequate to current challenges of internal and external origins.

Planetary scale geomagnetic secular variation foci in the last 400 years

Abstract The Earth's surface magnetic field and its secular variation (SV) are composed of several constituents, at sub-centennial (60–90 years) and inter-decadal (20–30 years) timescales, of internal origin, and at decadal (~11 years) timescale, of external origin, superimposed on a so-called inter-centennial constituent (timescale of about 400 years or larger). In this study we explore the appearance, structure, and dynamics of the SV foci from the perspective of the constituents with internal sources. Data from long time-span geomagnetic models, such as gufm1 (1590–1990) and COV-OBS (1840–2010), have been used to separate various constituents by Hodrick-Prescott (HP) and Butterworth filtering. Time-Longitude/Latitude plots, based on main field models time series on a grid of 2.5°x2.5° were constructed for various longitudes/latitudes respectively, on which a Radon transform was applied to get information on displacement in time of the constituents and of the SV foci, in the form of Latitude-Azimuthal-Speed and Longitude-Meridional-Speed power plots. The Earths surface field variability for the 400 years time-span is analyzed for the constituents of the field. Assessment of the geomagnetic field evolution at the Earth's surface and its characteristics, by our approach, revealed: (1) tendency of the westward drift of the inter-centennial constituent to the southern hemisphere, (2) absent meridional displacement of the inter-centennial constituent, (3) westward drift of the higher frequency constituents in a ± 20° equatorial band.

A Note on the Significance of Entropy Generation and Work Fluxes on Humid Air Inside a Solar Still Due to Double-Diffusive Natural Convection

The motion of the humid air inside a solar still is due to double-diffusive natural convection, where convective heat and mass transfer phenomena are encountered. The humid air, an intermediate medium between the evaporating and the condensing surfaces of the solar still, is regarded as a heat engine that absorbs heat from the free surface of the warmed brackish or saline water and converts it into work to carry up the water vapor molecules to the inner surface of the glass cover. Like all heat engines, the humid air work is accompanied by a degraded energy due to the presence of irreversibilities. The aim of the present study is to give answers about the internal irreversibility origins and the associated work fluxes of the humid air inside the solar still due to double-diffusive natural convection. It is for the first time that the internal entropy generation and the work fluxes formulations are developed and investigated for the humid air inside a solar still. It is found that the irreversibility rate due to fluid friction is the major contributor of the total entropy generation for N > 0.3. The increase in the temperature and the concentration gradients enhances the augmentation of all irreversibility rates. The second law efficiency is an important parameter that should be evaluated to assess the system performance. The mean value of the irreversibility percentage is found equal to 6.83%. The reversible and the lost work fluxes increase with the increase in the humid air temperature.

Cele zarządzania ryzykiem w polskich przedsiębiorstwach sektora mediów notowanych na Giełdzie Papierów Wartościowych w Warszawie

Risk Management Objectives in Polish Enterprises in the Media Sector Listed on the Warsaw Stock Exchange Risk management is an extremely important domain of management, conditioning the develop­ment of enterprises and business continuity, as well as developing and maintaining a competitive position. The main purpose of this text is to identify and categorize the risk management objec­tives adopted in Polish enterprises in the media sector listed on the Warsaw Stock Exchange (WSE). The aim of empirical research was achieved through the use of triangulation of research meth­ods. The following methods were used in the research process: the method of analyzing the con­tent of source documents of the studied group of enterprises, the logic classification method and the comparative method. The main research findings indicate that: the overriding goal of risk man­agement in the surveyed companies formulating them in a hierarchical system is in most cases en­suring compliance with the applicable requirements of external and internal origin, and the specif­ic objectives (being components of the overarching goal) are mainly determined by the specificity of the media sector. The obtained research results refer to both the theory and practice of risk manage­ment among enterprises representing the media sector and may serve as a source of knowledge for the stakeholders of companies being listed entities, which constitutes the added value of this work.

Carotid ultrasound findings among patients successfully treated with endovascular thrombectomy for atherosclerotic internal carotid artery origin occlusion

Carotid ultrasound findings among patients successfully treated with endovascular thrombectomy for atherosclerotic internal carotid artery origin occlusion

Imaging in Pulsatile Tinnitus: Case Based Review.

Tinnitus refers to auditory perception of internal origin. It is a relatively common problem and affects men and women equally. Clinically, it may be divided as pulsatile or non-pulsatile and subjective and objective. Although pulsatile tinnitus (PT) is less common, it is more likely to be associated with underlying vascular tumors, lesions or anomalies. Imaging forms the baseline for evaluation of objective tinnitus, primarily in the form of computed tomography or magnetic resonance imaging. We present a review of common causes of PT, along with emphasis on key imaging findings.

Stress Mediating Genes in Aging, Health, and Longevity Traits: Effects of Multiple Interactions

Persistent stress of external or internal origin accelerates aging, increases risk of aging related health disorders, and shortens lifespan. Stressors activate stress response genes, and their products collectively influence traits. The variability of stressors and responses to them contribute to trait heterogeneity, which may cause the failure of clinical trials for drug candidates. The objectives of this paper are: to address the heterogeneity issue; to evaluate collective interaction effects of genetic factors on Alzheimer’s disease (AD) and longevity using HRS data; to identify differences and similarities in patterns of genetic interactions within two genders; and to compare AD related genetic interaction patterns in HRS and LOADFS data. To reach these objectives we: selected candidate genes from stress related pathways affecting AD/longevity; implemented logistic regression model with interaction term to evaluate effects of SNP-pairs on these traits for males and females; constructed the novel interaction polygenic risk scores for SNPs, which showed strong interaction potential, and evaluated effects of these scores on AD/longevity; and compared patterns of genetic interactions within the two genders and within two datasets. We found there were many genes involved in highly significant interactions that were the same and that were different within the two genders. The effects of interaction polygenic risk scores on AD were strong and highly statistically significant. These conclusions were confirmed in analyses of interaction effects on longevity trait using HRS data. Comparison of HRS to LOADFS data showed that many genes had strong interaction effects on AD in both data sets.

Micropropagation of Tulip via Somatic Embryogenesis

An effective method of tulip regeneration via somatic embryogenesis (SE) was developed. Explants, flower stem slices excised from cooled bulbs were incubated in darkness on MS modified media containing auxins alone (2,4-dichlorophenoxyacetic acid—2,4-D, 1-naphthalene acetic acid—NAA and 4-amino-3,5,6-trichloro-2-pyridine carboxylic acid—picloram) or combined with thidiazuron (TDZ) at 0.1 and 0.5 mg L−1. Yellowish-white callus with a granular structure was developed in the presence of all auxins on the cut surface from the tissues of the vascular bundles. From this, lines of embryogenic calli were derived. The addition of TDZ to the medium with auxins significantly stimulated somatic embryo formation. Cyclic and the most intensive proliferation of embryogenic callus as well as embryo formation was obtained in the presence of 2,4-D at 0.1 mg L−1 combined with TDZ at 0.5 mg L−1. Addition of proline enhanced either callus proliferation rate or frequency of embryo formation. The best quality embryos with cotyledons longer than 10 mm able to form bulbs were recorded when TDZ was replaced with 6-benzylaminopurine (BAP) at the concentration of 0.1 mg L−1. Histomorphology showed that the development of somatic embryos could have either external or internal origins. Embryos of external origin were initiated by cell division on the edge of embryogenic calli. Embryos of internal origin resulted from the division of parenchyma cells inside the tissue. Embryonic cells were characterized by their small volume, regular shape, dense cytoplasm and large nuclei. The globular embryos were covered by a distinct layer of periderm. Then, the embryos developed into structures having leaf-shaped cotyledons with a procambial strand and a sideward-orientated meristem of the vegetative apex (stolon). Cotyledon embryos did not show vascular connections with the parent tissue, and they did not develop embryonic roots.

Predictors of Clopidogrel Hyper-Responsiveness in Neuro-Interventional Procedures

BackgroundHyper-responsiveness to clopidogrel abnormally inhibits platelet aggregation and increases hemorrhagic complications. The present study investigated clinical factors related to clopidogrel hyper-responsiveness in neuro-interventional procedures. MethodsTwo hundred twenty-four patients receiving clopidogrel for coil embolization to treat unruptured cerebral aneurysm or carotid artery stenting to treat carotid artery stenosis at the internal carotid artery origin were retrospectively reviewed for their P2Y12 reactivity unit (PRU) values and clinical characteristics. Hyper-responsiveness to clopidogrel was defined as a PRU of <95. ResultsThe mean PRU was 218.2 ± 77.8. Hyper-responsiveness to clopidogrel was observed in 12 patients (5.4%). Hyper-responsiveness was observed in younger patients, patients with a lower concentration of hemoglobin A1c, and patients with a higher low-density lipoprotein cholesterol (LDL-C) concentration compared with non-hyper-responsive patients (P = 0.01, P < 0.01, P < 0.01, respectively). On analysis of concomitant drugs, the patients in the hyper-responsive group were less frequently administered calcium channel blockers (CCBs) compared with the non-hyper-responsive group (P = 0.01). No significant differences in the usage of proton pump inhibitors or statins were observed. A LDL-C concentration of >120 mg/dL and no usage of CCBs were significant independent predictors of hyper-responsiveness to clopidogrel with a multivariate analysis (OR; 6.16, 95% CI, 1.57–26.64, P = 0.01, OR; 0.09, 95% CI, 0.01–0.82, P = 0.03, respectively). ConclusionThe present study shows that a higher LDL-C concentration and no usage of CCBs are independent predictors of clopidogrel hyper-responsiveness. These results are useful to predict perioperative hemorrhagic complications. Considering dose reduction of clopidogrel or alternative drugs in high risk cases is necessary to prevent perioperative hemorrhagic complications.

Pandemics and the politics of difference: rewriting the history of internationalism through nineteenth-century cholera

AbstractThis article revisits the origins of internationalism in the field of health and shows how the cholera epidemics of the nineteenth century, much like the current coronavirus crisis, brought global differences such as social inequalities, political hierarchies, and scientific conflicts to the fore. Beyond drawing parallels between the cholera epidemics and the current crisis, the article argues for combining imperial and social histories in order to write richer and more grounded histories of internationalism. It explores this historiographical and methodological challenge by analysing the boardrooms of the international sanitary conferences, Middle Eastern quarantine stations catering for Mecca pilgrims, and ocean steamships aiming to move without delay during a worldwide health crisis.

Variability in morphology and branching of the internal iliac artery: Implications for pelvic surgery

PurposeThe internal iliac artery displays variations that may predispose it to inadvertent injury during pelvic surgeries. This study aimed to describe variations of the internal iliac artery among Kenyans. Basic proceduresFifty-seven pairs of right and left-sided hemi-pelvises, 48 from males and 9 from females, were used in this study. We collected data on the internal iliac artery origin, relations, termination, branching, length and course of parietal branches. Data were then coded and entered into SPSS (version 21, Chicago, IL), where we performed descriptive statistics and analyses. FindingsIn all cases, the internal iliac artery originated singly from the common iliac artery. The IIA originated above the vertebral level of the L5/S1 disk (pelvic brim) in 30/57 (52.6%) cases, with the highest observed at L4. In most cases (32/57 [56.8%]), the IIA terminated at S1 vertebral level. The internal iliac artery lay medial, anterior and lateral to the sacroiliac joint in 37/57 (64.9%), 18/57 (30.6%) and 2/57 (5%) cases, respectively. Regarding parietal branching, 39/57 (64.8%) cases had a type 1 pattern as per the Adachi classification. The mean diameter and length of the internal iliac artery were 7.32 ± 1.69 mm and 36.97 ± 14.12 mm, respectively. The differences in dimensions of the IIA between the left and the right sides were not significant. Principal conclusionsA considerable proportion of the Kenyan population demonstrates an origin of the internal iliac artery above the pelvic brim. Unique termination via trifurcation and ramification may also be observed in the Kenyan population. Surgeons and radiologists performing vascular interventions in the pelvis should be mindful of these variations.

Fiscal Risks Faced by Moroccan SMEs

Taxation has become one of the major preoccupations of any company since “Better tax management means better financial management”. To do this, a company must not only have a good knowledge of the legal and tax environment in which it operates but also a good understanding of the fiscal risks it may face. This situation is perhaps even more pronounced in tax matters because of the financial burden that tax imposes on the company and because of the permanent risk of control and, where appropriate, sanctions to which the company is exposed. The concern of the company, in general, and the SME in particular, is above all to be informed of the existence of fiscal risks and to assess the extent and importance of these risks. This article presents fiscal risks as a source of stakes and challenges for Moroccan SMEs (Small and Medium Enterprises). These fiscal risks may have different natures, sources and areas. Our work aims at better understanding the origins of sources of fiscal risks. In order to carry out our research, we conducted a survey of 78 SMEs to find out the real origins of sources of fiscal risks faced by Moroccan SMEs. What are they? Are they of internal or external origin? The results show that fiscal risks have both internal and external origins, which leads Moroccan SMEs to question how to manage these risks in order to increase their results and achieve performance.

Abundance and characteristics of microplastics in soils with different agricultural practices: Importance of sources with internal origin and environmental fate

Despite intensive use of plastics in agriculture, little is known about the occurrence of microplastics (MPs) in agro-environment. To identify the effect of internal sources and environmental fate on MP appearance in farmland, we examined four soil types with different agricultural practices representing either direct application of polyethylene (PE) film—the inside (GS-in) and outside (GS-out) soils of greenhouse and mulch-film use soils (MS)—or rare use of plastics (rice-paddy soils; RS). MP abundance was 10–7630 items kg−1, with the order of GS-in, GS-out, RS, and MS. Besides the highest MP abundance, rare PE-sheet (4% of MPs) and increased MP abundance with sizes decreasing were unique for GS-in, implying the presence of internal sources other than PE-film and continued MP accumulation. Contrarily, in other outside soils high PE-sheet appearance (10–31%) indicated substantial input via fragmentation of applied PE-film (for GS-out and MS) or via surface-runoff (for RS) while drastic decline of small-sized MPs in order of MS > RS > GS-out than expected from steady-state fragmentation implied significant removal of MPs by surface runoff and/or infiltration. Our results suggest the importance of internal sources and environmental fate as significant factors affecting the occurrence of MPs in agricultural soils.

Salivary Redox Biomarkers in the Course of Caries and Periodontal Disease

Caries are a pathological process of extracorporeal nature, characterized by demineralization of inorganic substances as well as proteolysis triggered by acids produced by bacteria present in dental plaque, as a result of metabolism of sugars of both external and internal origin. Periodontal disease, on the other hand, is a multifactorial degenerative disease associated with inflammation, involving a group of tissues that surround the dental cervix and root of the tooth. It is believed that one of the mechanisms in the etiopathogenesis of caries and periodontitis are disorders of local and/or general oxidative stress (OS) parameters. Numerous clinical studies have confirmed the relationship between oxidative stress markers and oral diseases. In most analyzed studies, technical and biological variability was so high that none of the markers so far has proven suitable for routine clinical use. The aim of systematic reviews of the literature is to present the existing studies on OS parameters, mainly concerning the activity of antioxidant enzymes in saliva of patients with caries and periodontitis.

“You’re a Different Kind of Black—Where You From?”: The Qualifying Role of Place in the Construction of Black Racial and Ethnic Identities among Louisiana Creole Migrants

Much of the contemporary scholarship on Black identities focuses on how multiraciality, immigrant status, class, and neighborhood characteristics shape how social actors negotiate identities. In contrast, little analysis exists of how internal migration and regional origin or ancestry shape such negotiations. The study addresses this gap using interview data to examine how U.S.-born Black Louisianans with Creole heritage, who moved to Los Angeles along with their children during the Great Migration, actively negotiate racial/ethnic identities. The results show that participants negotiate identities situationally, especially when ambiguous appearances or surnames trigger interactional encounters in which they are mis-placed as “foreign” to the United States. Specifically, as migrants from one internal U.S. region to another, they use geographical references to situate Black racial and Creole ethnic identities (e.g., they refer to Louisiana or New Orleans) when interacting with non-Creole African Americans and non-Black people in Los Angeles. The study extends prior research on heterogeneous Black identities by demonstrating how internal migration, mixed racial/ethnic ancestry, and region of origin influence native-born Black American identities.

The mechanism of internal fatigue-crack initiation and early growth in a titanium alloy with lamellar and equiaxed microstructure

Traditionally, equiaxed α grains rather than lamellar microstructure (LM) domains in titanium alloys are regarded as potential internal crack origins in high-cycle fatigue (HCF) and very-high-cycle fatigue (VHCF) regimes. Here, we found that the fatigue crack is prone to initiate from a large LM domain in a titanium alloy with the composition of LM and equiaxed microstructure (EM) of fine α grains. Then, the mechanisms of internal crack initiation and early growth for the cases of HCF and VHCF under stress ratio R = −1, 0.1 and 0.5 were addressed and a mechanism chart was constructed to illustrate the internal cracking behavior, especially showing that the numerous cyclic pressing process dominates the related microstructure evolution with grain size refinement and nanograin formation underneath the fracture surfaces in the region of crack initiation and early growth.

High-efficiency somatic embryogenesis techniques for different hybrids of cut lilies

Somatic embryogenesis (SE) is a unique method of in vitro regeneration for plant reproduction, germplasm resource preservation, and molecular-assisted breeding. Although lily is an internationally valued ornamental plant, its SE technology is still incomplete. Here, the effects of different explants, picloram (PIC) concentrations, and light conditions on somatic embryo induction, development, germination and seedling formation were studied in five Lilium varieties belonging to different hybrids. The embryo histomorphology, development and origins were observed, and a broadly efficient embryogenesis system was firstly established in Lilium. With leaf explants, all varieties tested underwent indirect somatic embryogenesis (SE). With scale explants, the Lilium Asiatic ‘Strawberry and Cream’, Lilium Oriental ‘Double Surprise’, and Lilium longiflorum Thunb. ‘White Heaven’ underwent indirect SE and the Lilium longiflorum × Asiatic hybrid ‘Eyeliner’ and Lilium longiflorum × Oriental ‘Triumphator’ underwent direct SE. Somatic embryogenesis in the above varieties involved four stages: globular, heart-shaped, torpedo-shaped, and cotyledon embryos. Two original SE pathways (endogenous and exogenous) were observed, and their appearance times differed. In indirect SE, exogenous embryos appeared first, followed by endogenous embryos; whereas in direct SE, the order was reversed. The different somatic embryo origins and the proportion of internal and external origins were closely related to the occurrence of somatic embryos by direct or indirect pathways and significantly affected the induction cycle of somatic embryos. Dark culture promoted lily somatic embryo induction, while 16 h/day light culture promoted germination, and the germination rates of all five lily varieties exceeded 90%. Murashige Skoog (MS) medium + (1.5–2.5 mg L−1) PIC + 0.2 mg L−1 1-Naphthaleneacetic acid (NAA) was suitable for SE from lily leaves and scales with an induction efficiency of 88–96%. Our research developed a widely applicable regeneration procedure for different hybrids of lily via somatic embryogenesis. Morphohistological analysis confirmed the origins, developmental stages and dynamic changes of cells during in vitro morphogenesis. This study will provide a valuable reference for the propagation of Lilium.

Insight-related beliefs and controllability appraisals contribute little to hallucinated voices: a transdiagnostic network analysis study

Hallucinated voices cause high levels of distress and disability. Current theories suggest that insight-related beliefs, about internal or external origin, perceived source location, and appraisals of controllability are important in mediating the impact of these experiences but previous findings have been mixed. We report two open code and open data network analytic studies of items in the Psychotic Symptoms Ratings Scale for auditory verbal hallucinations (PSYRATS-AH) in a large sample of patients with hallucinated voices to examine the network structure of items at (1) first assessment, and (2) differences over two consecutive assessments during a wait-list period. Networks were generated using least absolute shrinkage and selection operator (LASSO) and extended Bayesian information criterion (EBIC) with node predictability. In Study 1 (N = 386), we report that insight-related items made a negligible contribution to hallucinated voices and the controllability appraisal made at most a modest contribution. Items relating to distress and negative content were the most central and most predicted by the wider network. In Study 2 (N = 204), we tested the longitudinal stability of the structure of hallucinated voices over a period of several months, finding a small change in total hallucination score and global strength but no clear evidence for an alteration in the structural relationship. The insight-related and controllability items remained as least influential over time. Insight-related beliefs and controllability appraisals may contribute less than previously thought to distressing hallucinated voices although we do not discount that other appraisals may remain important.

Analytical Method to Approximate the Impact of Turning on the Macroscopic Fundamental Diagram

Network macroscopic fundamental diagrams (MFDs) have recently been shown to exist in real-world urban traffic networks. The existence of an MFD facilitates the modeling of urban traffic network dynamics at a regional level, which can be used to identify and refine large-scale network-wide control strategies. To be useful, MFD-based modeling frameworks require an estimate of the functional form of a network’s MFD. Analytical methods have been proposed to estimate a network’s MFD by abstracting the network as a single ring-road or corridor and modeling the flow–density relationship on that simplified element. However, these existing methods cannot account for the impact of turning traffic, as only a single corridor is considered. This paper proposes a method to estimate a network’s MFD when vehicles are allowed to turn into or out of a corridor. A two-ring abstraction is first used to analyze how turning will affect vehicle travel in a more general network, and then the model is further approximated using a single ring-road or corridor. This approximation is useful as it facilitates the application of existing variational theory-based methods (the stochastic method of cuts) to estimate the flow–density relationship on the corridor, while accounting for the stochastic nature of turning. Results of the approximation compared with a more realistic simulation that includes features that cannot be captured using variational theory—such as internal origins and destinations—suggest that this approximation works to estimate a network’s MFD when turning traffic is present.