The management of uni- or bi-terminal edentulous cases in patients who cannot undergo implant-prosthetic treatment is complex and challenging, often requiring a multidisciplinary approach. Correct diagnosis, paraclinical investigations (retroalveolar radiographs, CBCT, blood tests), and a well-elaborated treatment protocol are usually necessary to achieve a predictable and successful outcome. The objective of complete rehabilitation of an arch includes identifying the cause, preventing, and conserving the remaining dental structure. This case study presents an interdisciplinary endo-prosthetic management through endodontic retreatment followed by the realization of a removable prosthesis restoration with extracoronal attachments. The prosthetic restoration yielded excellent functional and aesthetic results. Background. Oral rehabilitation of patients who cannot benefit from implant-prosthetic treatment. Case report. Restoration of the mandible using removable prostheses with extracoronal attachments. Conclusions. Removable prosthetic restorations remain a treatment solution in the era of implant prosthetics.