Inter-institutional Collaboration Research Articles

Development of a Pediatric Cardiology Cardiopulmonary Exercise Testing Database.

Cardiopulmonary exercise testing (CPET) provides clinicians with information vital to the management of pediatric cardiology patients. CPET can also be used to measure cardiorespiratory fitness (CRF) in these patients. CRF is a robust marker of overall health in children. However, a complete understanding of CRF in pediatric cardiology patients is limited by lack of large, standardized CPET databases. Our purpose was to develop a standardized CPET database, describe available data at our institution, and discuss challenges and opportunities associated with this project. CPETs performed from 1993 to present in an urban pediatric hospital were collected and compiled into a research database. Historical data included demographic and clinical variables and CPET outcomes, and additional variables were calculated and coded to facilitate analyses in these cohorts. Patient diagnoses were coded to facilitate sub-analyses of specific cohorts. Quality assurance protocols were established to ensure future database contributions and promote inter-institutional collaborations. This database includes 10,319 CPETs (56.1% male), predominantly using the Bruce Protocol. Patients ranging from ages 6 to 18years comprise 86.8% of available CPETs. Diagnosis classification scheme includes patients with structurally normal hearts (n = 3,454), congenital heart disease (n = 3,614), electrophysiological abnormalities (n = 2,082), heart transplant or cardiomyopathy (n = 833), and other diagnoses (n = 336). Historically, clinicians were provided with suboptimal interpretive resources for CPET, often generalizing inferences from these resources to non-representative clinical populations. This database supports representative CRF comparisons and establishes a framework for future CRF-based registries in pediatric patients referred for CPET, ultimately improving clinical decision-making regarding fitness in these populations.

A bibliometric and visual analysis of publications on artificial intelligence in colorectal cancer (2002-2022).

Colorectal cancer (CRC) has the third-highest incidence and second-highest mortality rate of all cancers worldwide. Early diagnosis and screening of CRC have been the focus of research in this field. With the continuous development of artificial intelligence (AI) technology, AI has advantages in many aspects of CRC, such as adenoma screening, genetic testing, and prediction of tumor metastasis. This study uses bibliometrics to analyze research in AI in CRC, summarize the field's history and current status of research, and predict future research directions. We searched the SCIE database for all literature on CRC and AI. The documents span the period 2002-2022. we used bibliometrics to analyze the data of these papers, such as authors, countries, institutions, and references. Co-authorship, co-citation, and co-occurrence analysis were the main methods of analysis. Citespace, VOSviewer, and SCImago Graphica were used to visualize the results. This study selected 1,531 articles on AI in CRC. China has published a maximum number of 580 such articles in this field. The U.S. had the most quality publications, boasting an average citation per article of 46.13. Mori Y and Ding K were the two authors with the highest number of articles. Scientific Reports, Cancers, and Frontiers in Oncology are this field's most widely published journals. Institutions from China occupy the top 9 positions among the most published institutions. We found that research on AI in this field mainly focuses on colonoscopy-assisted diagnosis, imaging histology, and pathology examination. AI in CRC is currently in the development stage with good prospects. AI is currently widely used in colonoscopy, imageomics, and pathology. However, the scope of AI applications is still limited, and there is a lack of inter-institutional collaboration. The pervasiveness of AI technology is the main direction of future housing development in this field.

Global historical retrospect and future prospects on biomarkers of heart failure: A bibliometric analysis and science mapping

IntroductionHeart failure is a rapidly growing public health problem and has become a major cause of hospitalization in middle-aged and older adults. Biomarkers are clinically important in managing heart failure and have attracted more attention from researchers in recent years. This study aimed to evaluate the global research of heart failure biomarkers by bibliometrics and to identify the hot spots and perspectives for further advancement. MethodsSelection of relevant documents was from the Web of Science Core Collection. Microsoft Excel, VOSviewer, SciMA, and CiteSpace software were used for bibliometric analysis. ResultsAs of October 29, 2021, 5,978 documents for heart failure biomarkers have been identified from 1989 to 2021. European Journal of Heart Failure and Circulation respectively ranked first in terms of the number of publications and the number of co-citations. A total of 5,698 institutions from 90 countries participated in these publications, with the USA leading with 2,045 documents. The most productive institution was Harvard University. Januzzi, J.L. and Maisel, A.S. were the most productive and most cited authors respectively. Natriuretic peptide, copeptin, valsartan, ferric carboxymaltose, empagliflozin, preserved ejection fraction, myocardial fibrosis, and heart transplantation were hot themes. ConclusionsExtensive national and inter-institutional collaboration should be enhanced to bridge the gap between developed and less developed countries in heart failure biomarkers research. The research in this field seems to have reached a relatively mature stage, with a decrease in research fervor in recent years. The study of the natriuretic peptide family still has high centrality, with advances in the study of expression products and inflammatory markers. Cardiac fibrosis, cardiac remodeling, and therapies regarding heart failure have become hot spots.

AAPM BTSC Report 377: Physicist Brachytherapy Training in 2021-A survey of therapeutic medical physics residency program directors.

Brachytherapy (BT) was the first radiotherapeutic technique used to treat human disease and remains an essential modality in radiation oncology. A decline in the utilization of BT as a treatment modality has been observed and reported, which may impact training opportunities for medical physics residents. A survey of therapeutic medical physics residency program directors was performed as part of an assessment of the current state of BT training during residency. In March 2021, a survey consisting of 23 questions was designed by a working unit of the Brachytherapy Subcommittee of the American Association of Physicists in Medicine (AAPM) and approved for distribution by the Executive Committee of the AAPM. The survey was distributed to the directors of the Commission on Accreditation of Medical Physics Education Programs (CAMPEP)-accredited therapeutic medical physics residency programs by the AAPM. The participant response was recorded anonymously in an online platform and then analyzed using MATLAB and Microsoft Excel software. The survey was distributed to the program directors of 110 residency programs. Over the course of 6 weeks, 72 directors accessed the survey online, and 55 fully completed the survey. Individual responses from the directors (including partial submissions) were evaluated and analyzed. Nearly all participating programs (98%) utilize high dose rate BT treatments with 74% using low dose rate BT techniques. All programs treated gynecological sites using BT, and the next most common treatment sites were prostate (80%) and breast (53%). Overall, the residency program directors had a positive outlook toward BT as a radiotherapeutic treatment modality. Caseload and time limitations were identified as primary barriers to BT training by some programs. Based on the responses of the program directors, it was identified that the residency programs might benefit from additional resources such as virtual BT training, interinstitutional collaborations as well as resident fellowships. Programs might also benefit from additional guidance related to BT-specific training requirements to help program directors attest Authorized Medical Physicist eligibility for graduating residents.

Adapting Selection Schemes for Indigenous Cattle Improvement in Sub-Saharan Africa-A Review

Livestock keeping is an important livelihood option in the tropics and cattle play the major role. For sub-Saharan Africa, most of the cattle kept are of indigenous type exhibiting low to medium production coefficients. After realizing low impact with crossbreeding in improving their productivity during the first three quarters of the 20th century, many sub-Saharan Africa countries turned to adoption of selection schemes during the last quarter of the century. However, many countries still haven’t realized active operation of selection schemes for indigenous breeds improvement. Major constraints are unsustainable financing, weak coordination, inadequate policy support and weak technical foundation for animal breeding. Existing infrastructure networks are not supporting extensive operation of selective breeding. Systematized pedigree and performance data recording is lacking in many countries. Important guidelines for streamlining implementation of breeding operations among actors are not in place. Strategies for adapting selection schemes in sub-Saharan Africa should target exploitation of unique potentials of indigenous breeds and focus to the improvement of their productivity while also maintaining their adaptability. From the prevailing conditions, considering immediate transformation to farmer-operated central nuclei is not recommended in structuring the scheme. What is recommended is to start with dispersed village-based group pre-nuclei which are backed by institutional central nuclei. Important strategies in enabling effective operation with such structured schemes include evolving guidelines for implementing selection in terms of defining breeding objectives, increasing involvement of farmers, strengthening coordination of animal breeding, promoting inter-institutional collaboration, and considering some more government financial support.

The Consequences of Step 2 Clinical Skills Examination Discontinuation for Medical Schools and Sustainability Plans for Clinical Skills Assessment.

Comprehensive clinical skills examinations using standardized patients are widely used to assess multiple physician competencies. However, these exams are resource intensive. With the discontinuation of the Step 2 Clinical Skills (CS) exam in 2021, how medical schools will change their approaches to comprehensive clinical skills exams is unknown. This study explores school responses to this change and future directions of comprehensive clinical skills exams using the program sustainability framework. This cross-sectional, descriptive study surveyed medical school curriculum deans at 150 Liaison Committee on Medical Education-accredited U.S. medical schools from September to October 2021. The 30-question survey included questions about medical school and participant role, current comprehensive clinical skills exams, sustainability dimensions, and challenges and future directions. Descriptive statistics were used to characterize responses, and content analysis was used to identify themes in the open-ended responses. Educators at 75 of 150 institutions (50%) responded. Sixty-three respondents (84%) reported conducting a comprehensive clinical skills exam. The comprehensive clinical skills exam assessed readiness for graduation (51 [81%]), provided feedback for students (49 [78%]), evaluated curricula (38 [60%]), provided information for medical student performance evaluation or communication with residency (10 [16%]), and assessed other factors (6 [10%]), including preparation for Step 2 CS in the past and readiness for advancement to fourth year of medical school (multiple responses were allowed). Factors facilitating sustainability included sufficient funding to continue the exam (55 [87%]) and the belief that clinical skills assessment in medical school is now more important after discontinuation of the Step 2 CS exam (55 [87%]). Challenges to sustainability included organizational capacity and limited interinstitutional collaboration. Educators remain committed to the purpose of comprehensive clinical skills exams. Adapting to changed licensing requirements while sustaining clinical skills exams enables innovation and improvement in assessment of clinical competence.

MINORS AND DEVIANCE IN THE CONTEXT OF THE COVID-19 PANDEMIC FROM AN INSTITUTIONAL PERSPECTIVE

-The present research aims to analyze the phenomenon of deviance among minors from the perspective of specialists who work with them. The context of the Covid-19 pandemic represented a good opportunity to analyze the dynamics of the phenomenon of juvenile deviance, as many aspects of daily life have acquired other nuances through isolation, distancing, etc. Following the research, it was found that there are multiple causes of the propagation of this phenomenon, namely the deficient family environment due to the lack of parental supervision, the influence of social media, the influence of the entourage, etc.Through this research, some characteristics of minors who commit acts of deviance were proposed, as well as a profile of those who are at risk of becoming deviant. The results of the research show that an inter-institutional collaboration between the town hall, school, church and police could facilitate the reduction of deviance among minors-

Moving Beyond Mobility

The paper focuses on the project “Collaborative International, Intercultural & Interdisciplinary Learning (COIIIL)” of the partner institutions Technische Universität Dresden (GER), Stellenbosch University (ZAF), Shiraz University (IRN), and Bucknell University (USA). The project offers crucial insights into moving beyond mobility as the sole or primary mode of internationalization toward an international campus. The paper presents good intra- and inter-institutional collaboration practices and demonstrates how an interdisciplinary community of practice for digital internationalization was established between the partners. It systematically discusses the ‘lessons learned’ from this collaboration and outlines further general measures contributing to the positive development of international cooperation in academia. Finally, conclusions are drawn regarding the practical implications and direction for future research.The paper focuses on the project “Collaborative International, Intercultural & Interdisciplinary Learning (COIIIL)” of the partner institutions Technische Universität Dresden (GER), Stellenbosch University (ZAF), Shiraz University (IRN), and Bucknell University (USA). The project offers crucial insights into moving beyond mobility as the sole or primary mode of internationalization toward an international campus. The paper presents good intra- and inter-institutional collaboration practices and demonstrates how an interdisciplinary community of practice for digital internationalization was established between the partners. It systematically discusses the ‘lessons learned’ from this collaboration and outlines further general measures contributing to the positive development of international cooperation in academia. Finally, conclusions are drawn regarding the practical implications and direction for future research.

A Study on an Inter-Institutional Collaboration of Family, Community, and Buddhism for Thai Vulnerable Youth

The purpose of the study was to investigate the effects of the inter-organizational collaboration of family, community, and Buddhism on vulnerable youth knowledge and behaviors. The samples were 302 vulnerable youths in Khon Kaen in Northern Thailand. They were selected by purposive sampling using the criteria of family incomes, marital status of parents, and neighborhood. The other group of samples consisted of 10 officials with the responsibility to take care of vulnerable youth in their area. The instruments included an inter-institutional collaboration plan, a teen pregnancy knowledge test, a social adaptation test, a drug knowledge test, and an interview form. The data were gathered in August 2021 when the samples took part in 5 projects under the inter-institutional collaboration plan involving family, community, and Buddhism. The data were analyzed using frequency, percentage, mean score, standard deviation, and t-test. The qualitative data were analyzed by content analysis. The results study illustrates how a planned collaboration between institutions concerned with human development led to the development of knowledge and positive behavioral changes among vulnerable youths.

Disadvantaged Children – Between Poverty and the COVID-19 Pandemic

Children from disadvantaged socioeconomic and family backgrounds are one of the categories most severely affected by COVID-19. In this article, we analyze the impact of the pandemic on two categories of disadvantaged children: children living with their family of origin and who are the beneficiaries of day center services (DCS) and children living in family-type residential centers (FRC). The data analysis also reveals how public institutions (schools, administrative institutions) and private institutions (NGOs, business areas, representatives of cults, and national minorities) can work together to identify solutions and take action to support disadvantaged children. From the methodological point of view, we opted for qualitative research. Research results reveal that the pandemic affected both categories of children (difficult access to basic needs, and services, risk of dropping out of school, difficulties in the process of family reunification) but also that the intervention and inter-institutional collaboration reduced the negative effects on children, families and the community.

Radiomics in veterinary medicine: Overview, methods, and applications.

Radiomics, or quantitative image analysis from radiographic image data, borrows the suffix from other emerging -omics fields of study, such as genomics, proteomics, and metabolomics. This report provides an overview of the general principles of how radiomic features are computed, describes major types of morphological, first order, and texture features, and the applications, challenges, and opportunities of radiomics as applied in veterinary medicine. Some advantages radiomics has over traditional semantic radiological features include standardized methodology in computing semantic features, the ability to compute features in multi-dimensional images, their newfound associations with genomic and pathological abnormalities, and the number of perceptible and imperceptible features available for regression or classification modeling. Some challenges in deploying radiomics in a clinical setting include sensitivity to image acquisition settings and image artifacts, pre- and post-image reconstruction and calculation settings, variability in feature estimates stemming from inter- and intra-observer contouring errors, and challenges with software and data harmonization and generalizability of findings given the challenges of small sample size and patient selection bias in veterinary medicine. Despite this, radiomics has enormous potential in patient-centric diagnostics, prognosis, and theragnostics. Fully leveraging the utility of radiomics in veterinary medicine will require inter-institutional collaborations, data harmonization, and data sharing strategies amongst institutions, transparent and robust model development, and multi-disciplinary efforts within and outside the veterinary medical imaging community.

Mentoring for INnovative Design Solutions (MINDS): Key Design Considerations and Collaborative Teamwork across Universities for Clinical Translation

The main purpose of this paper is to share the Mentoring for INnovative Design Solutions (MINDS) Scholars Program developed by Alpha Eta Mu Beta, the International Biomedical Engineering Honor Society. The program’s goals are to (1) introduce biomedical engineering students to an open-ended design experience as part of interuniversity teams with industry and faculty mentors, and (2) develop the ability to create designs considering clinical translatability on teams with different backgrounds and areas of expertise. MINDS uses an experiential learning approach to (1) enrich student curricular experiences through inter-institutional collaboration, (2) build engineering design skills, including three key design considerations for clinical/commercial success: intellectual property protection, regulatory strategy, and market identification; and (3) emphasize the importance of end-user considerations. From 2015 to 2022, MINDS has involved 131 students from 50 universities and 22 faculty and industry mentors. Pre- and post-program surveys show statistically significant improvements in understanding of the design process, regulatory strategy, intellectual property protection, market definition, and key product requirements and features. Students also improved communication and teamwork skills. Many students indicated that MINDS participation made them more likely to choose careers that involve product development and/or entrepreneurship. Students attained a working ability to integrate market needs, regulatory strategy, and intellectual property considerations into the design process. They also further developed soft skills, such as conflict resolution, time management, and effective communication through the challenges of inter-institutional collaboration. Additionally, the program heightened their awareness of how biomedical devices and technologies can benefit society.

Kognitywne badania nad religią a antropologia kulturowa

Cognitive science of religion (CSR) is an interdisciplinary research project focusing on the cognitive foundations of religion. The aim of this article is to discuss the specificity of CSR and demonstrate that, although it is part of cognitive science, it can also be seen as an anthropological paradigm in its own right. I argue that such a view can be supported by highlighting the importance of cultural anthropology for the SCR genesis (especially the role of anthropological theories and the resulting research methods, the involvement of anthropologists in the emergence of the new paradigm) and stressing the way in which contemporary anthropology benefits from theories formulated within CSR, the debates they generate and inter-institutional collaborations. Thus, I wish to highlight the dual nature of CSR as part and parcel of both cognitive science and contemporary psychological anthropology.

Japan perspective on antimicrobial stewardship and solid organ transplantation.

The current situation, challenges, and opportunities related to antimicrobial stewardship for solid organ transplantations (SOTs) patients in Japan are not well known. We searched English and Japanese literature using Pubmed and Ichushi-Web (the Japanese medical literature search system provided by the Japan Medical Abstract Society) with relevant keywords including solid organ transplant, antimicrobial stewardship, and Japan. Hand searches of the references from the retrieved literature, including conference proceedings of The Japanese Association for Infectious Diseases, were conducted. The Japanese National Action Plan for antimicrobial resistance has brought attention to the importance of antimicrobial stewardship programs (ASPs) in Japan. According to national surveillance, the proportion of methicillin resistance among Staphylococcus aureus was 48%, while the proportion of vancomycin-resistance among Enterococcus faecium was 1.5% in 2019. Resistance against imipenem in Escherichia coli and Klebsiella pneumoniae in 2019 were 0.1% and 0.2%, respectively. Exploration of SOT-specific data on antimicrobial usage and drug resistance are warranted. A large questionnaire survey revealed a low proportion of hospitals with >500 beds implementing ASP toward immunocompromised patients. While the annual number of SOT in Japan has increased, the implementation of SOT-specific ASP varies among institutions. A coordinated ASP and exploration of the burden of antimicrobial resistance are needed for SOT patients in Japan. Promoting both intrainstitutional and interinstitutional collaboration is vital to the advancement of SOT-specific ASP in Japan.

Profile of brazilian research productivity grant holders with a background in pediatric dentistry.

This study outlines the profile of research productivity grant holders of the Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq (National Council for Scientific and Technological Development)] in the field of pediatric dentistry. A cross-sectional study with data collected from the Brazilian academic curriculum vitae database. The eligibility criterion was being a research productivity grant holder in pediatric dentistry from 2018 to 2020. In the period of interest, 215 individuals were research productivity grant holders in the field of dentistry, 33 of whom had graduate degrees (specialization, master's or doctorate) in pediatric dentistry. The period of scientific production and work concluded of advising of scientific initiation, master, doctoral and post-doctoral degrees was 2010 to 2020. Descriptive analysis was performed and the Kruskal-Wallis test was used to analyze associations (5% significance level) between productivity grant level (2, 1D, 1C, 1B or 1A) and year of obtainment of the doctoral degree. The VOSviewer (version 1.6.17) was used to present graphically the interinstitutional collaborations. The sample was composed of Level 2 researchers (66.7%), women (66.7%), researchers linked to institutions in the southeastern region of Brazil (81.8%), with a doctoral degree concluded prior to 2002 (51.5%), began working as a professor at a higher education institution prior to 2007 (78.8%) and the title of full professor (45.5%). No significant association was found between productivity grant level and year of conclusion of the doctoral degree (p = 0.10). Median (interquartile range) of scientific articles was 119 (37-312). The prevalence of citations (57.52%) and JCR articles (62.76%) was higher among female researchers. In conclusion, CNPq research productivity grant holders in pediatric dentistry are essentially represented by females from the southeast region of the country (UFMG and USP). However, males have proportionally greater productivity.

Identifying Human Remains from 20th Century Warfare: A State of the Field Essay.

As we continually reflect on the wars of the 20th century, identification of the remains of victims takes an increasingly prominent position in ongoing research. Existing work on the identification of human remains from 20th century wars primarily covers the determination of phenotypic characteristics, kinship and geographic origins, supporting the establishment of genetic information databases. Compared with standard forensic methods, DNA analyses have revealed greater effectiveness. The process of DNA analysis includes DNA extraction, genetic marker testing and data analysis. Protocols from ancient DNA research can be applied to degraded remains, and next-generation sequencing (NGS) techniques can compensate for shortcomings in the most commonly-used PCR-capillary electrophoresis typing. As it stands, wide-ranging inter-governmental and inter-institutional collaboration is necessary in order to set up NGS-based public databases, and thereby promote the identification of human remains and archaeological forensics.

The Use of Search Request Forms Can Identify Gaps in a Consumer Health Library Collection

A Review of: Giannopoulos, E., Snow, M., Manley, M., McEwan, K., Stechkevich, A., Giuliani, M. E., & Papadakos, J. (2021). Identifying gaps in consumer health library collections: A retrospective review. Journal of the Medical Library Association: JMLA, 109(4), 656–666. https://doi.org/10.5195/jmla.2021.895 Abstract Objective – The objective of this study was to determine if search request forms, which are used when a patron’s request for information cannot be fulfilled at the time of contact with the library team, can be used to identify gaps in consumer health library collections while offering some explanation for the gaps. Design – Retrospective case study of search request forms. Setting – A consumer health library at an academic cancer center in Canada. Subjects – Library patrons: Patients, Patient family, other members of the center, and unspecified. Methods – The researchers reviewed 260 search request forms submitted between 2013 and 2020. Of those, 249 records met inclusion criteria and were analyzed and coded. Coding included patron type, cancer diagnosis, information delivery, and content themes. This information was then used to identify gaps in the library collection and the reasons for the gaps. Main Results – Patients were the primary patrons, asking 62.9% of the questions, followed by family members at 22.5%. The most common cancer type researched was breast at 23.3%, then hematology at 16.5%. gynecology, gastrointestinal, genitourinary, and sarcoma were next between 10% and 8.4%. The remaining cancer types ranged between 6.0 % and 2.0%, with brain being the lowest. Of the questions asked, 60% revealed a gap in the collection. The gaps included rare cancer diagnosis, treatment options, and prognosis. There were data collected on why the information was unavailable. While 53% of the gaps were a result of limited health consumer information, 25% were a result of paywall restrictions or content restricted to members. Conclusion – Search request forms can be an effective tool in evaluating gaps in collections. In this study, the researchers were able to identify that breast cancer patients made up the most significant proportion of patrons, and the biggest gaps in the collection were related to their treatment decisions. One opportunity to bridge this gap is through collaboration with clinical teams in developing patient friendly resources on this topic. In addition, inter-institutional collaboration between libraries may also help. Continued review of forms can help inform collection decisions to better meet the needs of patrons.

Reconsidering Higher Education Organizations via ecosystem Thinking: Some Initial Thoughts

Providing optimal knowledge sharing has become increasingly important during the lockdown starting in early 2020. As a mechanism for sharing knowledge, education is also hugely impacted. Studying from home became feasible. On-campus learning had to change entirely to online within weeks. Besides preventing the spread of the virus, this shift allowed students to follow their courses anywhere. Physical distance to an institution is no longer a barrier to knowledge exchange. Online facilities offer students access to a broader field with an impact on the quality of education.
 The paper defines an ecosystem for higher education institutions (HEI) based on our own experiences with online learning, interviews, and literature reviews.
 The goal is to create a theorized environment where students can sign up for higher education (HE) classes, courses, programmes at different institutions across Europe. The ecosystem could create commonly shared quality standards from a decentralised perspective, potentially increasing learning quality and providing students with more freedom in their personal learning experiences. This paper does not serve as a full scientific proof but as a discussion.
 The proposed ecosystem foresees students to follow courses anywhere. It offers study-abroad programmes and inter-institutional collaborations with a centralised platform for knowledge management. Allowing students to choose classes institution-free would increase specialisation of those institutions and impact the quality of education.
 We will show that implementing a decentralised education system needs a bottom-up approach with a centrally formulated IT strategy to facilitate education exchange. Common quality standards, resilience, innovation, simplicity, inclusivity, maturity, and specificity are essential. For an adaptive system, governance, resistance, ownership, and communication ownership should adhere.
 Our proposed ecosystem of institution-free HE would benefit all parties involved. Students can tailor their learning experience and obtain the highest level of education possible. HEI benefit in improving the quality of their programmes due to added competition. They could also drop courses that students better take elsewhere, allowing for specialisation in specific fields.
 Such an ecosystem holds financial, administrative, and even legal limitations. However, institutions can implement step-by-step, giving affordance to the substantial bureaucracy that will inevitably ensue.

Applications of Bacteriocins of Lactic Acid Bacteria in Biotechnology and Food Preservation: A Bibliometric Review

Introduction: Due to the growing prevalence of antibiotic resistance in microorganisms and the demand for safe food, there is increasing interest in using natural bioproducts such as the antimicrobial peptides bacteriocins to extend the shelf-life of foods. This is because of their spectrum of activity, ease of synthesis and applicability. This study reports on the global trends in lactic acid bacteria (LAB) bacteriocins based research publications in the Web of Science core collections within the last 20 years (2000-2019), with specific focus to their applications in biotechnology and food science. Methods: Data analysis was undertaken using VOSviewer and HistCite software to evaluate relationships between articles and visualise research linkages amongst authors, institutions and countries. Results: In the 20 years under review, a total of 1741 bacteriocin related articles were published, with the most cited publication examining the anti-infective activity of Lactobacillus salivarius. The highest research output was recorded by the United States, followed by Spain and China. However, Europe as a continent had the highest research output with a higher inter-institution collaboration network and stronger food safety legislations. Discussion: The bibliometric analysis gave insights into the research areas, cooperation network of authors, co-citation maps and co-occurrence of keywords utilized in the research field and indicates that bacteriocin-based research is highly multidisciplinary with a global reach. Conclusion: Key focus is on the control of foodborne disease pathogens, search for new producer organisms and approaches to improve bacteriocin yield and application. This class of antimicrobial peptides has the potential to replace chemical food preservatives in the future.

Performance Management of The Regional Inflation Control Team Central Kalimantan Province In Inflation Control

Inflation control necessitates inter-institutional collaboration and coordination, particularly between Bank Indonesia and the government. To continue to increase cooperation, the Government and Bank Indonesia formed an Inflation Monitoring and Control Team (TPI) at the central level in 2005, followed by the establishment of a Regional Inflation Control Team (TPID) in 2008. It is vital to take strategic efforts to control and suppress inflation by forming the Central Kalimantan Regional Inflation Control Team with the collaboration of regional agencies (TPID). The goal of this article is to identify the performance management strategies used by TPID in Central Kalimantan to keep inflation under control. This study employs a qualitative descriptive method and is conducted in the field. The secretaries and members of the TPID in Central Kalimantan were the subjects of this investigation. The research data was gathered through observation, interviewing, and recording techniques, which were then validated through source triangulation and analyzed through simplification, presentation, and conclusion stages. The findings of this study show that TPID's administration of inflation control efforts in Central Kalimantan complies with Governor Regulation No. 10 of 2015's inflation control guidelines. Because the inflation control procedure carried out by the Central Kalimantan TPID is in accordance with the planning, organizing, executing, and regulating functions, the Central Kalimantan TPID indirectly performs a management function. The Central Kalimantan TPID's inflation control management was highly effective. The Central Kalimantan TPID's inflation control administration was fairly effective in keeping inflation in Central Kalimantan and Palangkaraya generally regulated and constant.