Intensive Period Research Articles

Parents’ experience of children’s transitions from intensive care unit after liver transplantation: A qualitative study

ObjectiveThe aim of this study was to understand parents’ perspectives on caring for children who underwent liver transplantation in the intensive care unit transition period and to provide a reference for the development of targeted intervention strategies. MethodsThirteen parents of children who underwent liver transplantation at a tertiary hospital in Hangzhou, Zhejiang Province were chosen for in-depth semi-structured interviews via purposive sampling. The interview data were analyzed and summarized via content analysis. FindingsThree themes were extracted, including a period of separation and suffering (being apart from child is tough, chilling atmosphere, and limited family access); being an overwhelming caregiver (hope coupled with worry, conflict of roles, and existential care dilemmas); and facing a new normal: searching for information and support (information on medical conditions, post-discharge care assistance, educational support, and peer support). ConclusionFor parents whose child underwent liver transplantation, the transition period from the intensive care unit to the general ward is challenging. Parents are burdened with several caregiving responsibilities and require a variety of information and support. It is advised that nurses should offer sufficient information and suitable educational approaches to enhance these parents’ capacity to care for their children and assist children and their parents in making a smooth transition. Implications for clinical practiceThis study highlights parents’ perspectives on caring for children with liver transplants transferred from the intensive care unit to a general ward. Transitional care is strenuous, evoking different feelings before and after transfer. The health care professionals should focus on the needs and challenges faced by parents who are caring for children with liver transplants during the intensive care unit transition period. To achieve this, it is critical to establish a supportive environment and provide suitable information and education for parents to enhance their caregiving abilities.

The Levels of Cortisol and Selected Biochemical Parameters in Red Deer Harvested during Stalking Hunts.

As a reactive species, the red deer is sensitive to both negative exogenous and endogenous stimuli. An intensive hunting period may have a particularly negative impact on game animals. The aim of this study was to determine the plasma cortisol level and biochemical parameters in 25 wild red deer (Cervus elaphus) harvested during stalking hunts in correlation with the sex and age of the animals. The mean cortisol concentrations in the stags and hinds analyzed in this study were similar (20.2 and 21.5 ng/mL, respectively). Higher HDL cholesterol values were found in the blood of the hinds than in stags (p < 0.05). Similarly, the mean levels of LDL cholesterol, lactate dehydrogenase, and alanine aminotransferase were higher by 21%, 16%, and 42%, respectively, in the blood of the hinds. In contrast, the levels of alkaline phosphatase, bilirubin, and aspartate aminotransferase were higher in the stags (by 30%, 49%, and 36%, respectively). There was a negative correlation of the cortisol concentration with urea and bilirubin and a positive correlation between cortisol and aspartate aminotransferase in the stags (p < 0.05). In turn, a negative correlation was found between the cortisol and urea levels in the hinds (p < 0.05). In summary, the stress caused by stalking hunts and the characteristic behavior of red deer during the mating season had an impact on chosen biochemical parameters. The increased concentration of cortisol resulted in a decrease in the carcass mass, which may lead to the deterioration of the physical condition of animals on hunting grounds.

Feminist Utopias in the Early Twentieth Century

ABSTRACT The first two decades of the twentieth century saw an intense period of international feminist organising and campaigning. Organisations such as the International Alliance of Women (1904), the Socialist Women’s International (1907), and the Women’s International League for Peace and Freedom (1915) exemplified the transnational geography of the movement. This was also a time in which women’s writing moved in new ways, imagining speculative utopian worlds to accompany their radical gender politics. This article examines two literary feminist utopias from the early twentieth century: Pauline Hopkins’s Of One Blood (1902–3) and Rokeya Sakhawat Hossain’s Sultana’s Dream (1905). While US writer Hopkins’s Of One Blood offers an early Afrofuturist or Black internationalist utopia that reflects women’s struggles, Hossain presents a simultaneously feminist and anti-colonial imagining of the world. Both these works, in an internationalist tradition, criticise both patriarchal and racist or colonial world orders, demonstrating the vital role played by literary utopian works in feminism of the early twentieth century.

Analysis of Noise pollution level in Enugu campus, of the University of Nigeria

Noise is sound of any kind that is undesirable and unwanted as part of the environment under consideration. It is one of the types of pollution that have great impact on our health and wellbeing. The occurrence of noise in our environment is increasing daily because of growing population and industrialization. Noise pollution have great consequences on our social and economic lives especially in teaching and learning environment, which is presumed to be in silent zone. It is worth investigating whether environment in which teaching and learning take place is in quiet condition? The aim of the study was to analyze the level of noise pollution at different locations in the University of Nigeria, Enugu Campus. The Nigeria Standard noise level for higher education institutions and hospitals should be 60 dB for day and 50 dBA for night. The Noise levels dBA was measured with the help of noise meter at 14 points and at a height of 1 m above the ground level within the campus at three different times (6–8 am, 12–2 pm and 4–6 pm). The total Leq noise level in the University of Nigeria, Enugu Campus is 70.94 dBA which is above the level recommended for educational institutions. The period of intensity of noise was recorded during afternoon, morning and evening respectively. This rate of noise level during the day is high and unsuitable for teaching-learning process. Therefore, university management should take proactive measures to regulate noise pollution within the campus and indeed, other university campuses in Nigeria.

Исследования математических моделей процессов деформаций зданий и сооружений

Purpose. The article is aimed at analyzing changes in the dynamic characteristics of a building and establishing the dependence of shear deformation accelerations on the building's storey to predict the effect of seismic vibrations on the technical condition of the building, taking into account the engineering and geological properties of the foundation. Methodology. A number of instrumental observations using geodetic devices, automated monitoring systems and engineering seismic stations were made to study the issues of assessing changes in the dynamic characteristics of high-rise buildings and structures. To create mathematical models of deformation processes of buildings and structures, the study of interaction of structural elements of the building with the engineering-geological structure of the ground in the upper and lower parts of the megapolis was proposed. Findings. The results on ground shaking intensity acceleration, effective duration, spectral coefficients and periods of spectrum maximum are obtained. The results of measurements of vibrations on different floors of a high-rise building based on instrumental records of seismic station of local and distant earthquake have been obtained. Dependences of accelerations of shear deformations on the floor of the building with regard to engineering-geological properties of the base have been established. Predictive models of deformation processes of the building taking into account dynamic characteristics of ground vibrations and energy class of earth crust movements have been proposed. Originality. The analytical technique of correlation analysis of random variables is proposed, by means of which normally distributed linear and nonlinear processes are studied to create a mathematical model of deformation processes of buildings of different storeys. Practical value. The obtained results of the study of deformation processes of buildings and their structural elements allow to predict the dynamic model of the process of displacements of points of the structure taking into account the dynamic characteristics of ground vibrations and energy class movements of the Earth's crust

Sustaining Military Surgeons and the Joint Trauma System: Current Efforts, Unique Challenges, and Proposed Strategies in an Era of Global Uncertainty.

Mini abstract US military assets have been integral to the response to global pandemics, natural disasters, civilian casualties, and combat care. Strategies are being implemented to strengthen the military health care system and curtail the erosion of relevant surgical skills and knowledge during periods of low combat intensity. However, additional challenges remain. We describe these strategies and obstacles but also explore potential solutions that may strengthen the readiness of military surgeons and combat trauma teams.

PENETRATION OF BORROWED HYBRIDS INTO THE KAZAKH LANGUAGE

Nowadays the history of linguistics is characterized by an intensive period of replenishment of the Kazakh language with foreign terms. The introduction of considerable amount of international words of foreign background and their quick combination in the Kazakh language is explained by fast changes of public and academic life. Many borrowed words were introduced to Kazakh language by different ways and the reason for these were connected with scientific, economic, political and cultural ties. The examples of hybrid words in Kazakh language and their origin within the unique dialects are given in this article. The structure for creating hybrid words using English and Kazakh languages and their functional characteristics are presented in this article. Hybrid words are considered to be borrowed words. Loan words are words which came from other dialects and they refer to the process of speakers adopting words from a source language into their native language. The penetration of hybrid terminology into Kazakh language and the development of Anglo-Kazakh bilingualism is a result of this very «internationalism» of the English language. This leads to the creation of a new language situation, the study of which is very relevant nowadays. Keywords: hybrid, language, loan words, lexicology, neologism, foreign words, word-building, terminology.

Top-down control of climate on long-term interactions between fires, tree-cover and soil erosion in a Mediterranean mountain, Corsica

Fire is a potential significant driver of soil erosion in the Mediterranean area, as it results in the partial removal of vegetation and the alteration of organic matter, affecting soil structure and stability. The erosion of particle sizes is influenced by the intensity and duration of rainfall, regulated by disturbance regimes and vegetation cover. We hypothesize that, during the Holocene, high fire frequency and intensity under precipitation control may have contributed to soil erosion, while plant cover and composition could have mitigated it. This plant cover, in turn, might have been influenced by biomass burning. To test this hypothesis, we conducted a detailed analysis of sediments spanning the last 11,500 years from a small mountain lake, Corsica, situated in the black pine forest belt. The high temporal resolution analysis (∼10 years per sample), used granulometry and loss-on-ignition as proxies for erosion and ecosystem productivity in both the lake and watershed, and fire and plant macroremains as fire and tree cover proxies, respectively. The correlation between particle size and the contents of organic or mineral matter with mean fire return intervals (FRI) revealed significant patterns. Long fire intervals were associated with more fine and coarse sands, whereas short mean FRI positively correlated with clay and, fine and coarse silt, along with higher total mineral and organic matter contents. These findings suggest that fires were more frequent when rain duration was sustained but runoff intensity was lower. Conversely, wildfires were less frequent during intense runoff periods (wetter climate). Unlike fire frequency, fire severity did not correlate with erosion, and tree cover and plant richness had minimal to no effect. The 8.2 kyr event was characterized by runoff transporting primarily coarse sands, i.e. a dry period with very intense rains. This suggests that the system is primarily top-down controlled by climate. Multimillennial erosion trends are influenced by fire frequency and precipitation regimes, whereas vegetation does not seem to have a mitigating effect on this process.

Battling arid adversity: unveiling the resilience of cotton in the face of drought and innovative mitigation approaches

Climate change has had significant impacts on agriculture, particularly on cotton production, where drought has emerged as a major threat worldwide. Long and intense dry periods in cotton-growing regions have become more frequent and severe. Drought stress severely affects various aspects of cotton plants, including chlorophyll pigments, carbohydrate metabolism, and enzyme activities related to fiber development, such as vacuolar invertase and sucrose synthase. Furthermore, drought stress disrupts the movement of nutrients toward the reproductive tissues in cotton, resulting in compromised pollen function, propagative failure, and fiber characteristics. To tackle these issues, scientists have made advancements in creating drought-resistant cotton varieties through transgenic methods or molecular breeding techniques, genome editing, CRISPR/Cas9, utilizing quantitative trait loci (QTL). Moreover, the application of plant growth regulators and mineral elements has displayed the potential to improve cotton’s ability to endure drought stress while also enhancing fiber yield and quality. These approaches activate stress-responsive signaling pathways, which could contribute to mitigating reproductive failure and improving fiber characteristics. While the impact of drought stress on cotton plants has been extensively studied, the variations in fiber quality resulting from drought stress are not yet completely understood. Current research has been focused on unraveling the mechanisms underlying these changes, including the physiological, biochemical, and molecular alterations during the multiplicative growth phase that contribute to poor fiber development. Understanding these mechanisms will facilitate the development of novel strategies to alleviate the adverse impact of worldwide weather changes on cotton growth and fiber quality. This research focuses on the drought stress in cotton cultivation and explores its different effects on cotton morphology, physiology, crop yield, and fiber characteristics as well as mechanisms by which cotton exhibits drought tolerance and highlights innovative strategies to mitigate drought stress.

Rewinding the Tape: Documentary Heritage to (Re)discover “Lost” Natural Hazards—Evidence and Inferences from Southern Italy

The knowledge of natural hazards that occurred in the past is essential for implementing forecasting and prevention actions, for managing risk, and identifying proper land use. Floods do not escape this rule. This article sheds light on an unknown intense rainfall period, which affected the Campania region and the territory of the current Molise region (Southern Italy) on October–November 1961. The period culminated in floods, particularly involving the town of Benevento (Campania region), which had been affected by several inundations over centuries. The research made an extensive use of unpublished archival sources. The documents allowed us to both outline the pluviometric and hydrological picture of the period and catalogue seventeen physical and environmental effects suffered by over two hundred municipalities. Furthermore, we also disclosed the economic consequences in the wide territory involved. Special attention was paid to Benevento, for which we also drew up the scenario map related to the 19 October flood. For this town, historical data were effective for developing and testing the hydraulic model of the Sabato and Calore Rivers, which overflowed at the site. In this regard, we made some considerations on the current flood risk of the town. From a methodological point of view, we stress the importance of a historical approach in close relationship to other expertise for the knowledge of natural hazards, tracing also some future perspectives. The research complies with the 2030 Agenda for Sustainable Development and its Goal 11 concerned with making cities and human settlements inclusive, safe, resilient, and sustainable. The research findings will be useful for scholars and practitioners for both improving flood hazard models and arranging archival research path. Finally, local authorities in charge of risk mitigation can also benefit from the research results.

Combination of Slow Deep Breathing Technique and Lavender Aromatherapy on Labor Pain Intensity Period I Active Phase in Maternity Patients Primipara at dr. Abdul Rivai Berau Hospital

Labor pain in the first stage of the active phase felt by primiparous mothers at dr. Abdul Rivai Hospital is like a strong and very scary stab, and in facing labor pain, primiparous mothers do not know how to deal with the pain they feel, so some primiparous mothers are agitated, screaming, hitting their husbands, asking for a Caesarean section without medical indication. This study aimed to determine the effect of the combination of the Slow Deep Breathing technique and lavender aromatherapy on the intensity of labor pain during the first active phase in primiparous mothers giving birth. The Study used pre-experimental methods and a group Pre-Test-Post-Test Design with a population of primiparous mothers giving birth at Dr Abdul Rivai Hospital, Berau Regency, with an average of 43 people per month, based on the Lameshow formula with a sample of 35 people. The research instrument uses the NRS scale. Data analysis used the Wilcoxon test. The score for labor pain in the first stage of the active phase before the combination of the Slow Deep Breathing technique and lavender aromatherapy carried was 8, and after the combination of the Slow Deep Breathing technique and lavender aromatherapy was 7. There is an effect of the combination of the Slow Deep Breathing technique and lavender aromatherapy on the intensity of labor pain in the active phase of the first stage in primiparous women giving birth (p-value = 0.000 &lt; ?: 0.05). This indicates that the combination of the Slow Deep Breathing technique and lavender aromatherapy influences reduces the intensity of labor pain during the first active phase in primiparous women giving birth

Physiological, anthropometric and athletic performance adaptations from completing a 1-month pre-season period. A two-year longitudinal study in female collegiate soccer players.

Collegiate coaches and integrative support staff often utilize pre-season as a brief and intense training period to prepare athletes technically, tactically, and physiologically, to meet the demands of competition during a soccer season. This study sought to examine the dose-response from performing on-field soccer activities during a four-week pre-season period in female collegiate soccer players, and if the magnitude in response was associated with accumulated exercise stress. A total of twenty-seven healthy female soccer players training as part of a collegiate soccer program volunteered to participate in this two-year longitudinal study. Data collection commenced prior to the start of each pre-season period, at the beginning of August, and was completed at the beginning of September, when pre-season ended. Data collection periods were separated by a 31-day period. Indices of cardiovascular function, anthropometry, and athletic performance were examined during each data collection period. Internal and external measures of accumulated exercise stress were recorded using the Polar Team Pro® system. When comparing the beginning to the end of pre-season, significant improvements were observed in body fat (%) [24.2 ± 6.0 "vs." 23.3 ± 5.6, p = 0.001], heart rate variability (rMSSD) [51.8 ± 25.1 "vs." 67.9 ± 34.6 ms, p = 0.002], resting heart (bpm) [73.8 ± 12.1 "vs." 64.3 ± 8.8, p = 0.001] and cardiorespiratory performance (YoYo IRTL-1) [925.8 ± 272.8 "vs." 1,062.6 ± 223.3 m, p = 0.001]. Significant reductions in musculoskeletal performance were observed through vertical jump height (cm) [24.9 ± 23.7, p = 0.04]. Change in the end of pre-season body weight (kg) was significantly associated with accumulated accelerations and decelerations [r ≥ 0.49, p = 0.01]. End of pre-season change in cardiorespiratory performance was significantly associated with both accumulated training load (au) and TRIMP (au) [r ≥ 0.63, p = 0.01]. In conclusion, performing a four-week pre-season period, involving only on-field training, can promote positive and significant adaptations in anthropometry, cardiovascular function, and athletic performance measures in female collegiate soccer players. The magnitudes of these adaptations were associated with both internal and external measures of accumulated exercise stress.

First results of the potential gradient variation in a tropical station in South America (Ica, Peru)

Measurements of the potential gradient (PG) under fair weather conditions at new locations are crucial for monitoring the global electric circuit. In this study, we analyzed the variations in PG recorded in Ica city, Peru, during the period from March 2018 to December 2022. Our analysis involved a detailed comparison of PG with various meteorological parameters such as rainfall, wind speed and direction, dust storms, dust devils and fog to establish the characteristic PG curve under fair weather conditions (referred to as the standard curve). We identified a significant threshold of 3.5 m/s for strong winds, which helps prevent the influence of sea breeze and dust lifting on PG. Our results showed the impact of 'Paracas' dust storms on PG, which aligns with patterns observed in other arid regions worldwide. Subsequently, we calculated monthly, seasonal, and annual averages of the standard curve which showed a response likely associated with local convective processes on the PG diurnal variation. Furthermore, the seasonal variation of PG reveals higher values during June, July, and August compared to December, January, and February. These differences are attributed to seasonal changes in aerosol concentrations, potentially influenced by biomass-burning activities in Peru. Additionally, we performed a wavelet transform analysis of PG hourly values. We found the periodicities of 1 day, ∼188 days, and 360 days which are related to the diurnal, semiannual and annual periods. During the months between January and March 2018 was found an intense period of ∼45-day likely associated with one of the strongest Madden-Julian Oscillation events. Through this comprehensive investigation, we deepen our understanding of the intricate relationships among meteorological conditions, sea breeze, dust storms, and the PG in arid regions like Ica.

ANAEROBIC ENDURANCE IN YOUNG FEMALE HANDBALL ATHLETES

Introduction: Handball is a team sport with intermittent characteristics, alternating high intensity stimuli with periods of low intensity. Handball is characterized by an aerobic predominance, but it is anaerobic stimuli that determine the actions of the game. As several anaerobic actions are performed during the game, understanding the resistance of this metabolism in athletes becomes important. Objective: To compare the variables of anaerobic resistance in young players from different handball positions. Materials and methods: twenty female players with an average age of 16.8± 0.8 years participated in this study. The Running Anaerobic Sprint Test (RAST) was performed, which consisted of 6 sprints of 35 meters of running. Maximum, average and minimum power (absolute and relative) and fatigue index were calculated. Statistics with mean, standard deviation were used. To compare the different groups, ANOVA was used. Results: It was possible to observe values without significant statistical differences between the athletes in absolute power. In relative powers, it was possible to verify that point guards and wingers had higher values than goalkeepers and pivots (p&lt;0.05). In relation to the fatigue index, wingers and point guards had lower values than goalkeepers and pivots (p&lt;0.05). Conclusion: both in terms of power and fatigue index, point guards and wingers have better anaerobic conditioning than strikers and pivots. And pivots have better anaerobic capacity than goalkeepers. Further research on this topic is suggested to further consolidate the subject.

Analysis of Albania's diplomatic relations with the Soviet Union during the years 1948-1959.

This paper aims to shed light on a very intense period of relations between Albania and the Soviet Union (USSR), focusing on the period from 1948 with the intensification of Albania's relations with the USSR until the termination of diplomatic relations in 1959. The paper will overview the USSR's relationship with Albania and its behaviour. The paper analyses a specific period between 1948 and 1959 as a case study. The analysis is conducted on context, actors, and outcomes. The research aims to identify key indicators and the implications of the relationship in both domestic and international contexts. The data sources include various materials such as interviews, films, newspapers, and books. The researchers have requested permission to use the Archival resources of the Albanian Central State Archives (AQSH), where they have made some non-state secret resources accessible. However, some of these resources can only be accessed within the archive, but the researchers have been permitted to use them. The facts show that the relations between Albania and the USSR benefitted Albania more. particularly with economic support from the USSR, which helped Albania emerge from the crisis and build the so-called 'socialist state.' Albania took its place in the international arena through these relations and contributions. The study, regardless of the issues it addresses, does not aim to exhaust the paper's topic but to contribute to the objective analysis and to have some impact on the continuation and deepening of the treatment of this topic. Albania's relations with the Soviet Union are still not fully revealed as long as many documents found in Russian archives are not available for study. But further, numerous documents show that this could be the 'best cover' to safeguard the interests and personal power of the leadership.

A narrative about the Defense of Muslim Sacred Space in Arab Folklore of the Modern Era

For many centuries, the history of the Levant and Arabia have been marked by the conflicts for control of sacred spaces between representatives of various faiths, and this confrontation continues to this day. One of the most intense periods of this struggle was the era of the Crusades, the study of the memory of which in folklore sources is an important scientific task. Of significant interest in this case is the narrative about the defense of Muslim sacred space, which developed in the socalled Arabic Folk Epics. Although the threat to sacred space in this type of sources often comes not from the Franks (ifranj), but from the Byzantines (rūm), and the action itself in some monuments takes place in pre-Islamic times, the whole complex of stories about the threat to sacred space in Folk Epics can be considered an echo of the Crusades. The Franks and Byzantines in the Epics regularly threaten both Jerusalem and Mecca. It can also be assumed with a high degree of confidence that, thanks to the great popularity of Folk Epics in the Modern Era, the idea of a European threat to Muslim sacred space survived in the collective memory of the Arabs of Egypt and the Levant until the 19th century.

Flower Strips as an Ecological Tool to Strengthen the Environmental Balance of Fields: Case Study of a National Park Zone in Western Poland

Maintaining biodiversity in agrocenoses is becoming an important element of sustainable development strategies. Flower strips can perform various functions, and their use in the agricultural landscape is a form of a natural mechanism for regulating the agricultural habitat and improving the effectiveness of biological methods of combating crop pests. This manuscript is a case study in Wielkopolska National Park, a valuable wildlife area situated in a temperate zone characteristic of the climate conditions of western Poland. The purpose of this study was to analyze the species composition of plants in a flower strip two years after sowing a mixture of seeds of perennial plants, and to determine the diversity of the collected arthropods depending on the flowering intensity of plants in the strip. The most intense flowering period in the flower strip occurred in June, when the number of flowering plants was the highest and belonged to one species, Trifolium repens (81.52% of all flowering plants). In the same month, the largest share of beneficial arthropods were specimens from Hymenoptera/Parasitica (29.15%), which may indicate their preference for T. repens. The share of beneficial arthropods in relation to all caught arthropods was higher in June (58.74%) than in July (35.16%), with Hymenoptera predominating, represented mainly by Parasitica, which may indicate their preference for species from the genus Trifolium.

On Survival

Abstract An expansion of my 2022 Charles Seeger Lecture, “On Survival” unfolds as a set of reflections on the moment in the history of ethnomusicology that has followed intense periods of response to the COVID-19 pandemic and of racial self-reckoning worldwide. While examining common concerns and practices for ethnomusicology as a field, I do not propose a new theory or method, but rather I argue for the unity of the field rather than the separation of approaches into subdisciplines. The common ground of the present ethnomusicological moment, like that of the past to which ethnomusicologists now return, lies in a fundamental concern for ethical practice and moral purpose. Throughout the article, I draw upon case studies, many from my own ethnographic and historical work, especially from my research in and performances of music of the Shoah, to claim affinity between the fields of ethnomusicology and moral philosophy. These affinities emerge from common engagement with the moral dimensions of survival: trauma, mourning, border crossing, goodness, cohabitation with others in the Anthropocene, transcendence. The video clips are available here: https://files.press.uillinois.edu/journals/supplemental/ethno/seeger_lecture/

The effect of exercise to cardiac fibrosis in mice with non-communicable diseases, especially myocardial infarction and diabetes mellitus: A literature review

Non-communicable diseases (NCDs) are chronic disease caused by multifactor mainly unhealthy lifestyle and are still have one of the highest mortality rate in the world. Cardiovascular manifestations are commonly found in several type of NCDs such as heart disease and diabetes Mellitus (DM). One of that cardiovascular manifestation is cardiac remodeling especially cardiac fibrosis. Regular exercise has been considered as the effective method to improve cardiovascular function in NCD patients especially heart disease and DM, it also can reduce cardiac fibrosis in mice with NCD. This review aims summarize the effect of various exercise to cardiac fibrosis in mice with NCD especially myocardial infarction and diabetes mellitus. From six studies that reviewed in this article, five of them found that exercise can reduce cardiac fibrosis in mice with myocardial infarction or diabetic mice. Further study is required to determine the effect of various exercise type, intensity, and intervention period to cardiac remodeling, especially cardiac fibrosis, in mice with other NCDs.

The effect of the faults to the tectono-stratigraphy evolution in the Panyu low uplift

Introduction: The Panyu low uplift is located in the middle of the Central Uplift Belt of the Pearl River Mouth Basin, which has experienced multiple episodes of tectonic movements since the Cenozoic, and the faults are extensively developed there. The fault activities had a significant influence on the migration and accumulation of oil and gas, as well as the sedimentation.Methods: In order to recognize the effect of the faults on the tectono-straigraphy evolution in the Panyu low uplift, based on the high-resolution seismic and latest drilling well data, the study has comprehensively analyzed the geometry and kinematics of these faults, as well as the sedimentary filling evolution of the residual depressions.Results: The results show that two major fault systems has developed in the Panyu low uplift: the deep and shallow fault systems. The former was dominated by a series of NEE and NW-trending high-angle listric/plane faults, along with several low-angle detachment normal faults, which were under the joint control of the NW-SE and NS-trending extensional stress during the Eocene. The latter was dominated by NW-NWW trending strike-slip normal faults with tension-shear properties under the NEE trending dextral strike-slip stress field in the late Miocene. The uplift had undergone five tectonic evolution stages: the initial rifting stage (Tg-T83), the intensive rifting stage (T83-T80), the rifting and depression transitional stage (T80-T70), the thermal subsidence depression stage (T70-T35), and the tectonic reactivation stage (T35-T10).Discussion: Based on the 3D seismic phase interpretation and drilling sample analyses, the study also indicates that during the initial rifting stage, the Panyu low uplift manifested as multistage depositional center. The sedimentary strata were distributed in the downthrown wall of the depression-controlling faults, exhibiting multiple subsidence and sedimentary centers, and the depressions was supplied by multi-provenance systems. During the intense rifting period, the depression widened, the lacustrine basins were connected with each other, and the sedimentary center migrated. During the rifting and depression transitional stage, the faults controlling on deposition weakened. The thick Enping formation from the northwest provenance direction is unconformably overlaid on the Panyu low uplift. Meanwhile, the depressions was characterized by the sedimentary deposits of lacustrine basin. Various types of sedimentary facies were developed, including the delta, semi-deep lacustrine, shallow lacustrine, and shore-shallow lacustrine deposits, and the mudstone of the semi-deep lacustrine facies could serve as a high-quality source rock for the hydrocarbon production.