Intensity Resistance Training Research Articles

Effect of various exercise training interventions on cardiac autonomic function in obese individuals: A systematic review and meta-analysis

The aim of the systematic review and meta-analysis was to investigate the effect of various exercise training interventions on cardiac autonomic function (CAF) in obese. We conducted electronic database search from SCOPUS, PubMed, Web of science and cochrane library from inception till August 2021. Among 3234 articles retrieved, 9 were found to be eligible for the present review. Studies investigating the effect of exercise interventions on CAF assessed either by linear or non-linear measures of heart rate variability (HRV), baroreflex sensitivity, or heart rate recovery were included. Of the studies retrieved, 9 were included in the systematic review. Meta-analysis was conducted on 5 studies. The findings of the qualitative analysis revealed low to moderate certainty of evidence for aerobic exercise (AE) while low to very low was documented for combined training (CT). Standardized mean differences (SMD) showed a large effect of AE on SD of normal to normal (N–N) intervals (SDNN) [SMD 1.35, 95% confidence interval (CI) −0.11, 2.81; p = 0.07] and root mean square of successive differences between adjacent inter-beat (R-R) intervals (RMSSD) [SMD 1.50, 95% confidence interval (CI) 0.12, 2.88; p = 0.03]. CT depicted moderate insignificant change in low-frequency power of HRV (LF; SMD −0.55, 95% CI −1.52, −0.42; p = 0.27). This systematic analysis revealed positive effect of exercise training on CAF in obese individuals. AE and CT have large and moderate impact on CAF respectively though the pooled result was insignificant for majority of the variables, while effect of HIIT and RT yet remains to be fully elucidated. • Obesity is strongly linked with the development of cardiac autonomic dysfunction. • Exercise training improves markers of cardiac autonomic function in obese. • Aerobic exercise has large impact on linear and non linear indices of heart rate variability. • In future, trials focusing on high intensity interval training and resistance training must be conducted.

Analysis of the Use and Applicability of Different Variables for the Prescription of Relative Intensity in Bench Press Exercise.

Simple SummaryThe aim of this research is to analyze the different variables that influence the prescription of resistance training (one-repetition maximum (1RM) and number of maximal repetitions (xRM)) through the velocity of execution, with the aim of approaching the precise definition and control of intensity in bench press exercise. Fifty male physical education students were divided into four groups according to their relative strength ratio (RSR) and performed a 1RM bench press test, and two maximum number of repetitions (MNR) tests one week apart, using a relative load corresponding to 70% 1RM determined through the mean propulsive velocity (MPV) obtained from the individual load–velocity relationship. Regarding MPV, the best (fastest) repetition of the set values were similar between groups (0.62 m·s−1–0.64 m·s−1). The average MNR was 12.38 ± 2.51, with significant variation between groups with regards to MNR (CV:13–29%), and greater variability in the group corresponding to the lowest RSR values (CV: 29%). The use of variables such as the 1RM or a MNR do not allow an adequate degree of precision to prescribe and control the relative intensity of resistance training. Besides, execution velocity control can offer an adequate alternative to guarantee an accurate prescription of intensity with regard to resistance training.Background: The aim of the study was to analyze the use of variables such as % of one-repetition maximum (1RM) and number of maximal repetitions (xRM) with execution velocity to define and control the intensity of resistance training in bench press exercise. Hence, exercise professionals will achieve better control of training through a greater understanding of its variables. Methods: In this cross-sectional study, fifty male physical education students were divided into four groups according to their relative strength ratio (RSR) and performed a 1RM bench press test (T1). In the second test, participants performed repetitions to exhaustion (T2), using a relative load corresponding to 70% 1RM determined through the mean propulsive velocity (MPV) obtained from the individual load–velocity relationship. This same test was repeated a week later (T3). Tests were monitored according to the MPV of each repetition and blood lactate values (LACT). Results: Regarding MPV, the best (fastest) repetition of the set (MPVrep Best) values were similar between groups (0.62 m·s−1–0.64 m·s−1), with significant differences in relation to the high RSR group (p < 0.001). The average maximum number of repetitions (MNR) was 12.38 ± 2.51, with no significant differences between the RSR groups. Nonetheless, significant variation existed between groups with regards to MNR (CV: 13–29%), with greater variability in the group corresponding to the lowest RSR values (CV: 29%). The loss of velocity in the MNR test in the different groups was similar (p > 0.05). Average LACT values (5.72 mmol·L−1) showed significant differences between the Medium RSR and Very Low RSR groups. No significant differences were found (p > 0.05) between T2 and T3 with regards to MNR, MPVrep Best, or MPVrep Last, with little variability seen between participants. Conclusions: The use of variables such as the 1RM, estimated using an absolute load value, or an MNR do not allow an adequate degree of precision to prescribe and control the relative intensity of resistance training. Besides, execution velocity control can offer an adequate alternative to guarantee an accurate prescription of intensity with regard to resistance training.

Effects of resistance training intensity on muscle quantity/quality in middle-aged and older people: a randomized controlled trial.

BackgroundA sarcopenia diagnosis is confirmed by the presence of low muscle quantity or quality under the 2018 revised definition by the European Working Group on Sarcopenia in Older People 2. Imaging methods [i.e. magnetic resonance imaging (MRI)], dual‐energy X‐ray absorptiometry (DXA), and bioelectrical impedance analysis are tools to evaluate muscle quantity or quality. The present study aimed to investigate whether and how low‐intensity and moderate‐intensity resistance training improved both muscle quantity and quality measured by MRI, DXA, and segmental bioelectrical impedance spectroscopy (S‐BIS) in middle‐aged and older people.MethodsA single‐blind, randomized, controlled trial was conducted. Community‐dwelling people aged 50–79 years were randomly allocated to no exercise (no‐Ex), low‐intensity exercise (low‐Ex), and moderate‐intensity exercise (moderate‐Ex) groups. Participants in the exercise groups performed resistance training for 24 weeks, with loads of 40% and 60% of one repetition maximum in the low‐Ex and moderate‐Ex groups, respectively. Cross‐sectional area (CSA), lean mass, and muscle electrical properties on S‐BIS were used to determine the effects of training interventions on muscle quantity and quality of the lower limbs.ResultsFifty participants (no‐Ex 17, age 63.5 ± 8.5 years, women 47.1%; low‐Ex 16, age 63.6 ± 8.1 years, women 50.0%; moderate‐Ex 17, age 63.5 ± 8.3 years, women 52.9%) completed the 24 week exercise intervention. For the primary outcome, significant intervention effects were found in thigh muscle CSA on MRI between the moderate‐Ex and no‐Ex groups (+6.8 cm2, P < 0.01). Low‐Ex for 24 weeks only increased quadriceps CSA (+2.3 cm2, P < 0.05). The per cent change of thigh muscle CSA (+7.0%, P < 0.01) after 24 week moderate‐Ex was higher than that of leg lean mass on DXA (+2.3%, P = 0.088). Moderate‐Ex for 24 weeks also improved S‐BIS electrical properties related to muscle quantity and quality, including the intracellular resistance index (+0.1 cm2/Ω, P < 0.05), membrane capacitance (+0.7 nF, P < 0.05), and phase angle (+0.3 deg, P < 0.05); their changes were positively correlated with that of thigh muscle CSA (P < 0.01).ConclusionsResistance exercise with moderate intensity improved muscle quantity and quality measured by MRI and S‐BIS, whereas that with low intensity only increased muscle quantity in middle‐aged and older people. The comparisons among the responses to exercise between the assessment methods indicate the greater value of MRI and S‐BIS to measure changes of muscle quantity and quality than of lean mass measured by DXA for assessing the local effects of resistance training.

NUTRITION ERGOGENIC SUPPLEMENTS REGULATE BLOOD PH. - AN UPDATE

Ergogenic nutritional supplements are a type of sports food. Sodium bicarbonate and b-alanine are two of the most popular and legally permitted ergogenic dietary supplements. These two chemicals have a comparable ergogenic effect because they help to neutralize hydrogen cations created during anaerobic glycolysis during exercise. The hydrogen ions will exit the trained muscles faster if the extracellular regulatory capacity of the organism is increased by strengthening the stores of bicarbonate ions. And before the acidification within the muscle cells becomes a limiting factor of athletic performance, more hydrogen ions and lactic acid will be produced. The goal of this review is to go over the two most common dietary supplements, sodium bicarbonate and b-alanine, that have been shown to improve athletic performance by neutralizing hydrogen cations created during anaerobic glycolysis during exercise. Sodium bicarbonate and b-alanine are legal ergogenic aids that are inexpensive and simple to make, and they have been used by athletes for decades. The extracellular mechanism of "neutralization" of hydrogen ions that build in the exercised muscle is aided by sodium bicarbonate consumption, which increases bicarbonate concentrations in the blood. The ideal dose is between 0.3 and 0.5 grams per kilogram of body weight, and it should be consumed 150-180 minutes before exercise to minimize or lessen gastrointestinal problems. B-alanine supplementation can also improve anaerobic exercise performance, with a more apparent effect in trials lasting 1 to 4 minutes at high intensity, whereas its ergogenic effect appears to be minimal to moderate in exercises lasting up to 25 minutes. Furthermore, it improves the volume of resistance training; yet, increasing strength has no added advantage. Carnosine reserves in muscle are greatly increased after 4 weeks of administration (4-6 gr/day), operating as an intramuscular mechanism for controlling H+ concentration. Furthermore, a loading dose of 4-6 grams per day in doses of 2 grams or fewer is necessary for a least of 2 weeks, with a larger benefit after 4 weeks. Paraesthesia is the sole negative effect at the prescribed levels (tingling).&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;strong&gt; Article visualizations:&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;&lt;img src="/-counters-/edu_01/0915/a.php" alt="Hit counter" /&gt;&lt;/p&gt;

A Systematic Review of The Effects of Different Resistance Training Volumes on Muscle Hypertrophy.

The main goal of this study was to compare responses to moderate and high training volumes aimed at inducing muscle hypertrophy. A literature search on 3 databases (Pubmed, Scopus and Chocrane Library) was conducted in January 2021. After analyzing 2083 resultant articles, studies were included if they met the following inclusion criteria: a) studies were randomized controlled trials (with the number of sets explicitly reported), b) interventions lasted at least six weeks, c) participants had a minimum of one year of resistance training experience, d) participants’ age ranged from 18 to 35 years, e) studies reported direct measurements of muscle thickness and/or the cross-sectional area, and f) studies were published in peer-review journals. Seven studies met the inclusion criteria and were included in the qualitative analysis, whereas just six were included in the quantitative analysis. All participants were divided into three groups: “low” (<12 weekly sets), “moderate” (12-20 weekly sets) and “high” volume (>20 weekly sets). According to the results of this meta-analysis, there were no differences between moderate and high training volume responses for the quadriceps (p = 0.19) and the biceps brachii (p = 0.59). However, it appears that a high training volume is better to induce muscle mass gains in the triceps brachii (p = 0.01). According to the results of this review, a range of 12-20 weekly sets per muscle group may be an optimum standard recommendation for increasing muscle hypertrophy in young, trained men.

HIIT and Resistance Training Effects on Learning-related Outcomes in Underserved School Children

Research has demonstrated associations between differing modalities of physical activity (PA) and behavioral and learning outcomes; however, little evidence exists in real world settings. To evaluate the effects of embedding high intensity interval training (HITT) and resistance training (RT) into physical education (PE) curriculum on PA, academic performance, and behavior in youth attending urban schools. Forty boys and 30 girls; ages 8-10 yrs. enrolled in an expanded public school supplemental learning program were assigned into one of three conditions using a pragmatic trial design: standard PE curriculum (n = 23), HITT (n = 25), and RT (n = 22). PA was measured using accelerometers; math achievement scores were conducted at baseline and post-intervention using the Math Knowledge Assessment (MKA); behavior was assessed using the Abbreviated Conners Rating Scale (ACRS) daily. Participation in HITT resulted in 1.86 additional vigorous PA minutes (p=0.04) and 0.76 additional very vigorous PA minutes (P=0.02) per session, but was not associated with increased moderate PA minutes compared to the control group. RT PA outcomes did not differ from regular PE. Participating in HIIT, but not RT, was associated with a 1.82-point improvement in math test scores compared to those in the same grade in the standard PE group (p=0.02). No group assignment was associated with behavioral ratings. Embedding HITT within PE has potential for improving vigorous PA levels and may affect learning outcomes in urban youth. This is consistent with prior studies which show how short bouts of intense exercise can improve cognitive outcomes.

Exercise Intensity and Rest Intervals Effects on Intracellular Signals and Anabolic Response of Skeletal Muscle to Resistance Training

Moro, T, Monaco, L, Naro, F, Reggiani, C, and Paoli, A. Exercise intensity and rest intervals effects on intracellular signals and anabolic response of skeletal muscle to resistance training. J Strength Cond Res XX(X): 000–000, 2021—Resistance training (RT) is one of the most important stimuli for muscle hypertrophy, and it may play also an important role on weight loss and fatty acids oxidation. Clearly, RT affects anabolic pathways, but the differences among various training techniques has been poorly investigated. We sought to compare the effect of 2 different intensities of training: high-intensity interval resistance training (HIIRT) and traditional resistance training (TRT), on muscle signaling pathway. Nine young healthy subjects performed HIIRT and TRT protocol on 2 different occasions and with different legs on leg extension. High-intensity interval resistance training technique consisted of 3 sets of 6 repetitions (reps) at 6 repetition maximum and then 20 seconds of rest and 2 or 3 repetitions (until exhaustion) repeated for 3 times with 2′30″ rest between sets, whereas TRT consisted of 3 sets of 15 reps with 75 seconds of rest between sets. Biopsies from the vastus lateralis were taken at baseline (pre), immediately (0 hours) at the end of training, and 6 hours (6 h) and 24 hours (24 h) after training. Western blot and real-time polymerase chain reaction messenger RNA (mRNA) analysis were performed to assess muscle signaling pathway activation. In both protocols, rpS6 phosphorylation significantly increased at 6 hours (p < 0.05). Traditional resistance training showed a significant increase at 24 hours of AMPK phosphorylation compared with HIIRT (p < 0.05), whereas no significant differences between groups were found for other proteins. mRNA analysis showed no differences between protocols except for striated muscle activator of Rho signaling. The manipulation of resistance training intensity through incomplete/short recovery does not induce different molecular anabolic and metabolic responses compared with a TRT method. Trial Registration number: NCT04163120 retrospectively registered.

Effect of intensity sequence of resistance training on some antioxidants factors and Malondialdehyde plasma in over weight men

Background and Aims: Todays, many factors and variables are considered in the design of resistance training that may affect physiological adaptations. Despite the positive effect of resistance training on antioxidant behavior and oxidative stress, the influents of these factors to intensity sequence of resistance training is unclear. The purpose of this study was to determine the effects of resistance training intensity sequence of resistance training on antioxidants and Malondialdehyde (MDA) in over weight men. Methods: In present semi experimental study, 30 over weight young males voluntarily participated in the study and randomly assigned to pyramid resistance training (PRT; n=10), reverse pyramid resistance training (RPRT; n=10), and control (n=10). Resistance training was done in 3 nonconsecutive days for eight weeks, where the PRT was done resistance training by gradually increasing the intensity and decreasing the number of repetitions to reach maximum strength, while the RPRT they did the exact opposite. Blood samples were collected before and 48 after exercise training, and superoxide dismutase (SOD), Malondialdehyde (MDA), glutathione peroxidase (GPX), and total Antioxidant capacity (TAC) were measured by McCord &amp; Fridovich, Buege&amp; Aust, Paglia &amp; valentine and FARP methods, respectively. In order to analyze the data, analysis of variance was used with repeated measurements. Results: It was observed that SOD in the PRT (p=0.024) and the RPRT (p=0.029) increased significantly. The GPX in the PRT (p=0.008) and RPRT (p=007) than to control were also significantly increased. Also, the TAC increased significantly only in the PRT (p=0.047). The MDA in the PRT (p=0.019) and the RPRT (p=0.041) were significantly decrease, no significant difference was observed between PRT and RPRT in any of the mentioned variables (p˃0.05). Conclusion: Based on the results of the study, it seems that pyramid and reverse pyramid resistance training can improve the antioxidant status in overweight men, however, they have not any advantages than to each other.

Two vs. One Resistance Exercise Sessions in One Day: Acute Effects on Recovery and Performance

ABSTRACT Purpose: The purpose of this study was to compare the recovery response of one resistance training session (1TRS) vs. two resistance training sessions (2TRS) performed in 1 day, on upper body performance, muscle morphology and muscle soreness in trained men. Methods: Twenty-four resistance trained men were randomly assigned into a 1TRS group (N = 12; age = 25.0 ± 2.4 years; body mass = 87.6 ± 14.0 kg; height = 177.1 ± 4.9 cm) or into a 2TRS group (N = 10; age = 24.4 ± 1.6 years; body mass = 81.1 ± 5.6 kg; height = 176.6 ± 6.7 cm). 1TRS performed one training session involving eight sets of 10 reps at 70% of 1RM at the bench press, while 2TRS group divided the same training volume in two workouts, with a recovery time of 4 hr. Performance [bench press throw power (BTP) and isometric bench press (IBP)] and muscle thickness of pectoralis major (PECMT) were assessed at baseline (BL), 15-min, 24-hr and 48-hr post-exercise. Results:Training intensity was significantly higher in 2TRS compared to 1TRS (p < .001). Faster recovery rates were detected for BTP (p = .039) and PECMT (p = .05) in 2TRS compared to 1TRS. Both BTP and PECMT were significantly more affected (p < .05) in 1TRS than in 2TRS at 24 h. Conclusions:Results indicate that the recovery process may be accelerated by splitting a high resistance training volume into two different training sessions performed in 1 day.

The effects of adding high-intensity of effort resistance training to routine care in persons with type II diabetes: An exploratory randomized parallel-group time-series study

AimsThis study considered the effects of supervised, low volume, high intensity of effort resistance training compared to continued routine care in persons with type II diabetes. MethodsWe utilized a randomized parallel-group time-series design. All participants completed baseline testing (T0) and then participated in an educational training intervention regarding the management of their diabetes and were followed up for six months, during which they received routine care before being retested (T1). Participants were then randomly allocated to either continue with routine care (CON) or receive the high intensity of effort resistance training intervention (HIT). Participants from both groups were retested again after six months (T2). All participants were followed up for a further 12 months before being finally tested (T3). Data were available from 57 participants who completed the whole duration of the study (HIT, n = 29; CON, n = 28) for measures of anthropometry (body mass, waist circumference, and BMI), body composition (body fat mass, body fat percentage, lean mass, and visceral fat mass), total body water, phase angle, HbA1c, fasted blood glucose, and subjective wellbeing (WHO-5). ResultsDuring the initial 6-months of routine care significant improvements were noted for waist circumference, body fat mass, lean mass, body fat percentage, lean mass percentage, visceral fat mass, HbA1c, fasted blood glucose, and subjective wellbeing. During the successive 6-months (intervention) and 18-months (follow-up), data suggest that many of these positive changes during the initial 6-months were negated or reversed for CON. In contrast, participants engaging in HIT continued to show positive changes for waist circumference, body fat mass, lean mass, body fat percentage, lean mass percentage, and visceral fat. For blood markers and wellbeing, HbA1c continued to decrease, fasted blood glucose decreased, and subjective wellbeing continued to increase. These positive responses were still evidenced and significantly different compared to CON after the 12-month follow-up. ConclusionThe results of this exploratory pragmatic trial suggest that the addition of high intensity of effort RT alongside routine care can have a positive impact on a range of outcomes in type 2 diabetics having undergone prior routine care.

The Relationship Between Arterial Stiffness and Resistance Training.

Exercise is a critical factor that impacts arterial stiffness. In this narrative review, we noted multiple findings that could not be reconciled with one another. Some studies indicated that arterial stiffness increases after a regimen of resistance training. However, such studies were limited by a lack of specification of the resistance training protocols, as well as varying results reported from different areas of the body, undermining the internal validity of the studies. Another factor explored in this review was how the order of performing exercises can affect arterial stiffness. Low-intensity resistance training before high-intensity resistance training resulted in increased arterial stiffness, whereas vice versa showed no change in arterial stiffness. Other studies indicated that resistance exercise results in reduced arterial stiffness. Intensity is a variable in studies that produces inconsistent results of arterial stiffness, with some studies suggesting high-intensity resistance training increases arterial stiffness and low-intensity resistance training decreases arterial stiffness, while other studies pointing to a significant decrease in arterial stiffness, regardless of the intensity of resistance training. Demographic factors such as gender, age, and diet play an important role in explaining these differences. In terms of future implications, there is potential clinical significance as increased arterial stiffness serves as a prognostic marker in diagnosing coronary heart disease.

The Maximum Flywheel Load: A Novel Index to Monitor Loading Intensity of Flywheel Devices.

Background: The main aim of this study was (1) to find an index to monitor the loading intensity of flywheel resistance training, and (2) to study the differences in the relative intensity workload spectrum between the FW-load and ISO-load. Methods: twenty-one males participated in the study. Subjects executed an incremental loading test in the squat exercise using a Smith machine (ISO-load) or a flywheel device (FW-load). We studied different association models between speed, power, acceleration, and force, and each moment of inertia was used to find an index for FW-load. In addition, we tested the differences between relative workloads among load conditions using a two-way repeated-measures test. Results: the highest r2 was observed using a logarithmic fitting model between the mean angular acceleration and moment of inertia. The intersection with the x-axis resulted in an index (maximum flywheel load, MFL) that represents a theoretical individual maximal load that can be used. The ISO-load showed greater speed, acceleration, and power outcomes at any relative workload (%MFL vs. % maximum repetition). However, from 45% of the relative workload, FW-load showed higher vertical forces. Conclusions: MFL can be easily computed using a logarithmic model between the mean angular acceleration and moment of inertia to characterize the maximum theoretical loading intensity in the flywheel squat.

The acute effect of different intensity aerobic and resistance training exercise on the body image in adult women

The purpose of the study was to evaluate the acute effect of different intensity aerobic (AE) and resistance training (RT) exercises on BI in adult women. Participants were 62 adult women (19.47 ± 2.53 yr., range 18 a 33 yr.), who were randomly assigned to three sessions of either: 1) Control group, 2) Low-intensity AE, 3) High-intensity AE, 4) Low-intensity RT, or 5) High-intensity RT. Before and immediately following each experimental intervention, BI, body weight, and arm and leg circumferences were measured. Three familiarization sessions were performed every 7 days before the AE and RT experimental interventions. Also, 5-RM tests were performed one week before the RT experimental interventions. Data were analyzed using mixed 3-way ANOVA, mixed 4-way ANOVA, and post-hoc analysis. An acute effect of RT on BI was observed, regardless of the exercise intensity, women felt more muscular immediately following the RT session. Regardless of the exercise intensity, 30-min of acute RT exercise changed BI perception, contrary to 30 min AE.

The effects of resistance training with blood flow restriction on muscle strength, muscle hypertrophy and functionality in patients with osteoarthritis and rheumatoid arthritis: A systematic review with meta-analysis.

IntroductionRheumatoid arthritis(RA) and osteoarthritis(OA) patients showed systemic manifestations that may lead to a reduction in muscle strength, muscle mass and, consequently, to a reduction in functionality. On the other hand, moderate intensity resistance training(MIRT) and high intensity resistance training(HIRT) are able to improve muscle strength and muscle mass in RA and OA without affecting the disease course. However, due to the articular manifestations caused by these diseases, these patients may present intolerance to MIRT or HIRT. Thus, the low intensity resistance training combined with blood flow restriction(LIRTBFR) may be a new training strategy for these populations.ObjectiveTo perform a systematic review with meta-analysis to verify the effects of LIRTBFR on muscle strength, muscle mass and functionality in RA and OA patients.Materials and methodsA systematic review with meta-analysis of randomized clinical trials(RCTs), published in English, between 1957–2021, was conducted using MEDLINE(PubMed), Embase and Cochrane Library. The methodological quality was assessed using Physiotherapy Evidence Database scale. The risk of bias was assessed using RoB2.0. Mean difference(MD) or standardized mean difference(SMD) and 95% confidence intervals(CI) were pooled using a random-effects model. A P<0.05 was considered statistically significant.ResultsFive RCTs were included. We found no significant differences in the effects between LIRTBFR, MIRT and HIRT on muscle strength, which was assessed by tests of quadriceps strength(SMD = -0.01[-0.57, 0.54], P = 0.96; I² = 58%) and functionality measured by tests with patterns similar to walking(SMD = -0.04[-0.39, 0.31], P = 0.82; I² = 0%). Compared to HIRT, muscle mass gain after LIRTBFR was reported to be similar. When comparing LIRTBFR with low intensity resistance training without blood flow restriction(LIRT), the effect LIRTBFR was reported to be higher on muscle strength, which was evaluated by the knee extension test.ConclusionLIRTBFR appears to be a promising strategy for gains in muscle strength, muscle mass and functionality in a predominant sample of RA and OA women.

Combined exercise training improved exercise capacity and lung inflammation in rats with hepatopulmonary syndrome

AimPhysical exercise training attenuates pulmonary inflammation, but its effects on impaired respiratory function caused by hepatopulmonary syndrome (HPS) have not been evaluated. We determined if the combination of moderate intensity aerobic and resistance training during HPS development modifies exercise capacity, respiratory system mechanics, and lung inflammation responses. Main methodsWistar rats were randomly divided into sham, HPS, and HPS + combined exercise training groups. Fifteen days after HPS induction, a moderate intensity aerobic plus resistance exercise training protocol was performed five times a week for 5 weeks on alternate days. Exercise capacity, respiratory system mechanics, lung inflammation, pulmonary morphology, and immunohistochemistry were evaluated. Key findingsOverall, our findings indicated that combined exercise training efficiently increased the maximal running and resistance capacity of HPS animals. The training regimen reduced the expression of P2X7 in parenchymal leukocytes (P < 0.01), partially restored the expression of interleukin-10 in airway epithelium (P < 0.01), and increased the expression of TFPI in the airway epithelium (P < 0.01) as well as reduced its expression in parenchymal leukocytes (P < 0.01). However, exercise training did not attenuate HPS-induced respiratory mechanical derangements or lung tissue remodeling. SignificanceCombined exercise training can elicit adaptation with regard to both maximal running capacity and maximum strength and modify the expression of P2X7 and TFPI in parenchymal leukocytes and that of IL-10 in airway epithelium.

Resistance training improves nerve conduction and arterial stiffness in older adults with diabetic distal symmetrical polyneuropathy: A randomized controlled trial

Diabetes is the main cause of peripheral neuropathy where older patients are at increased risk of diabetic distal symmetrical polyneuropathy (DSPN) due to age-related nerve degeneration and vascular changes. The aim of the study was to investigate the effect of resistance training on nerve conduction, measures of neuropathy and arterial stiffness in older patients with DSPN. In a randomized controlled trial, thirty-four older adults with type-2 diabetes and peripheral neuropathy were enrolled and randomly assigned to experimental and control groups. The experimental group carried out circuit resistance training (1-3 rounds, 11 exercises, 10-15 reps, 50%-60% of 1RM, 3 times per week) for 12weeks. Measurements were performed at baseline and 48h after the intervention. Measures of DSPN including Michigan neuropathy screening instrument (MNSI), Michigan diabetic neuropathy score (MDNS), motor nerve action potential amplitude (APA), sensory and motor nerve conduction velocity (NCV) improved following intervention (p<0.001, p=0.001, p=0.034, p=0.001, and p=0.001, respectively). Sensory APA did not change after the intervention (p=0.139). Cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) improved in the experimental group compared with the control group (p=0.014 and p=0.033, respectively). In addition, HbA1C decreased following the 12-week resistance training program (p=0.002). Older adults with DSPN respond positively to resistance training by improved neuropathy symptoms, nerve conduction, arterial stiffness and glucose regulation. Resistance training offers a positive intervention that can abate the progression of DSPN in older adults.

Effect of moderate intensity resistance training with blood flow restriction on muscle strength and girth in young adults-a randomized control trial.

To examine the effects of moderate intensity resistance training with blood flow restriction on muscle strength and forearm girth. Total of 39 students enrolled in this study were divided into three groups that is group A (control group), group B and group C. Group A performed exercise training without restrictive pressure, group B and C performed exercise training with 50 and 75mmHg respectively. Both the outcome measures were evaluated on day 1 and day 12th with the help of digital dynamometer and measuring tape. Repeated measure ANOVA with Post hoc analysis was done using SPSS software version 20. The result of the study showed significant (p≤0.05) within subject improvement in muscle strength and muscle girth in all the three groups. However, significant improvement in muscle strength was found in between group analysis (p≤0.05). The results of the study can be concluded as the partial blood flow restriction (50mmHg) with moderate intensity resistance training resulted in greater handgrip strength than the other two groups. No difference was found in forearm girth among the three groups, however within the group difference was found.

The Effect of Resistance Training in Healthy Adults on Body Fat Percentage, Fat Mass and Visceral Fat: A Systematic Review and Meta-Analysis.

Resistance training is the gold standard exercise mode for accrual of lean muscle mass, but the isolated effect of resistance training on body fat is unknown. This systematic review and meta-analysis evaluated resistance training for body composition outcomes in healthy adults. Our primary outcome was body fat percentage; secondary outcomes were body fat mass and visceral fat. Systematic review with meta-analysis. We searched five electronic databases up to January 2021. We included randomised trials that compared full-body resistance training for at least 4weeks to no-exercise control in healthy adults. We assessed study quality with the TESTEX tool and conducted a random-effects meta-analysis, with a subgroup analysis based on measurement type (scan or non-scan) and sex (male or female), and a meta-regression for volume of resistance training and training components. From 11,981 records, we included 58 studies in the review, with 54 providing data for a meta-analysis. Mean study quality was 9/15 (range 6-15). Compared to the control, resistance training reduced body fat percentage by - 1.46% (95% confidence interval - 1.78 to - 1.14, p < 0.0001), body fat mass by - 0.55kg (95% confidence interval - 0.75 to - 0.34, p < 0.0001) and visceral fat by a standardised mean difference of - 0.49 (95% confidence interval - 0.87 to - 0.11, p = 0.0114). Measurement type was a significant moderator in body fat percentage and body fat mass, but sex was not. Training volume and training components were not associated with effect size. Resistance training reduces body fat percentage, body fat mass and visceral fat in healthy adults. osf.io/hsk32.

What's all the hype with fibre type? Selective single fibre adaptations with lifelong endurance exercise.

What's all the hype with fibre type? Selective single fibre adaptations with lifelong endurance exercise.

Effects of Cannabidiol Supplementation on Skeletal Muscle Regeneration after Intensive Resistance Training.

Cannabidiol supplements (CBD) are increasingly consumed by athletes to improve regeneration. However, the evidence for the pro-regenerative effects of CBD in sports is quite limited. Therefore, our aim was to investigate the effects of a single CBD supplementation in a six-arm placebo-controlled crossover study after resistance training on performance and muscle damage. Before and after the resistance training, one-repetition maximum in the back squat (1RM BS), countermovement jump (CMJ), and blood serum concentrations of creatine kinase (CK) and myoglobin (Myo) were measured in healthy, well-trained participants. 16 out of 21 participants completed the study and were included in the analysis. In 1RM BS, a significant decrease was observed after 24 h (p < 0.01) but not after 48 and 72 h. A significant group difference was detected after 72 h (p < 0.05; ES = 0.371). In CMJ, no significant changes were observed. The CK and Myo concentrations increased significantly after 24 h (CK: p < 0.001; Myo: p < 0.01), 48 h (CK: p < 0.001; Myo: p < 0.01) and 72 h (CK: p < 0.001; Myo: p < 0.001). After 72 h, significant group differences were observed for both muscle damage biomarkers (CK: p < 0.05 ES = 0.24; Myo: p < 0.05; ES = 0.21). The results show small but significant effects on muscle damage and recovery of squat performance after 72 h. However, more data are required for clearer statements concerning potential pro-regenerative effects of CBD supplementation after resistance training.