Objectives: The core objective of this paper is to introduce the explicit Modified Laguerre polynomial 𝐿𝑎,𝑏,𝑐,𝑛 (𝑡) and obtain a new general integral transform of Modified Laguerre’s Polynomial, by using this general transform, some transforms of Laguerre’s Polynomial are identified as special cases. Method: We derive transforms of the polynomials 𝐿𝑎,𝑏,𝑐,𝑛 (𝑡), 𝐿𝑛 (𝑡) by using this new integral transform approach and found the transforms like Laplace, 𝛼-Laplace, Sawi, Elzaki, Sumudu, Natural, Aboodh, Pourreza, Mohand, G_transform, Kamal transforms and their relationship for the same. Findings: A new general integral transform of the Modified Laguerre’s Polynomial 𝐿𝑎,𝑏,𝑐,𝑛 (𝑡) has been obtained, and a special case for the polynomial 𝐿𝑛 (𝑡) has been derived by using this transform. Novelty: This is a novel general integral transform for this polynomial and by applying this transform to the Modified Laguerre’s polynomial as special transform cases like Laplace, 𝛼-Laplace, Sawi, Elzaki, Sumudu, Natural, Aboodh, Pourreza, Mohand, G_, Kamal, Sumudu, Elzaki, Natural, and Pourreza are obtained. Keywords: Modified Laguerre polynomial; Laguerre polynomial; A New Integral Transform; Laplace Transform; Sumudu Transform