This study aimed to identify the effects of basal thumb surgery on the range of dart thrower's motion. Thirteen fresh-frozen cadaveric specimens were placed in a customized jig. Simulated scaphotrapeziotrapezoid joint fusion was carried out on all specimens. Half the specimens then underwent trapeziectomy and the rest had excision of the distal pole of the scaphoid. Simulated scaphotrapeziotrapezoid fusion reduced the range of dart thrower's motion to 89% of the range in the intact wrists, from a mean of 117° to 104°. Although this reduction is not large, it was statistically significant. Simulated trapeziectomy caused a very small increase in dart thrower's motion range compared with the range in the intact wrists. Simulated distal pole of scaphoid excision did not change the range of dart thrower's motion. These results may inform preoperative decisions for surgical management of basal osteoarthritis of the thumb.