Sulphur hexafluoride (SF6), the most popular dielectric medium adopted in compressed gas insulated equipment, has been identified as a highly potent greenhouse gas. This has led to increased interest in finding a more environmentally friendly replacement candidate. In this paper, the technical viability of C3F7CN/CO2 gas mixtures was assessed as a potential retro-fill solution for existing SF6-filled gas insulated lines (GIL) and busbars (GIB). A reduced-scale coaxial prototype was developed to establish the breakdown strength of 20% C3F7CN / 80% CO2 and 16% C3F7CN / 84% CO2 gas mixtures in direct comparison with pure SF6 under the standard lightning impulse (1.2/50 μs). Breakdown results demonstrate that a mixture of 20% C3F7CN / 80% CO2 exhibits comparable insulation capability to pure SF6 in coaxial geometries with similar field uniformity to GIL/GIB. This initial finding has led to the construction of a full-scale GIB demonstrator rated for 420/550 kV. Type tests according to IEC 62271–204 showed that the 20% C3F7CN / 80% CO2 gas mixture has passed all the required voltage levels as SF6. The research findings in this paper are an encouraging step towards a technically viable SF6-free retro-fill solution for existing GIL/GIB installed for the 400 kV transmission network in the UK.