Objectives This study aims to develop experimental activities using remote-control technology and apply them to prospective middle school chemistry teachers to explore the potential of the developed 'acid-base titration' chemistry inquiry experiment as a new experimental method.
 Methods The participants, consisting of 20 prospective teachers majoring in chemistry education from a university in the central region, engaged in a 4-session experiment where they remotely operated equipment, observed chemical experiment situations, and collected real-time data. Subsequently, based on their remote-controlled experiment experiences, surveys and semi-structured interviews were conducted to assess participants' experiences related to inquiry, alleviation of isolation, and a sense of realism in online settings.
 Results Remote-controlled experiments were divided into 'remote control of equipment' and 'remote control of data processing.'Remote control of equipment' involved sending signals to experimental devices through Blynk, wirelessly transmitting these signals to operate laboratory equipment. 'Remote control of data processing' allowed participants to use remote control functions to store and process experimental data in an Excel file. The developed remote-controlled inquiry experiment program in this study (1) provided prospective middle school chemistry teachers with experiences of basic inquiry functions such as observation and measurement, as well as integrated inquiry functions such as data interpretation and conclusion derivation, even in online experimental situations; (2) confirmed real-time learner-centered interactions, including learner-learner interactions and learner-content/ interface interactions; and (3) demonstrated a high level of presence in terms of teaching, cognitive, and affective realism.
 Conclusions Despite being a remote-based experiment class, it was evident that providing prospective teachers with opportunities for experiences and interactions in scientific inquiry activities could alleviate isolation and enhance a sense of realism. This study is expected to offer insights into designing and implementing the entire process of inquiry teaching in an online context.