BackgroundEvaluating the attitudes of nursing students towards scientific research is pivotal for enhancing the quality of care and reinforcing evidence-based nursing practices. Therefore, nursing students to embody a disposition towards openness to cultivate innovative thinking to effectively discern and address the evolving needs within nursing care services. AimThis study was conducted to determine the effects of nursing students' attitudes towards scientific research and related factors on their individual innovation profiles. MethodsA total of 375 nursing students were included in the study. The data were collected using a Demographic Information Form, Individual Innovativeness Scale and Attitude towards Scientific Research Scale. For between-group comparisons, the student t-test and One-way ANOVA were utilized for normally distributed data, whereas the Mann-Whitney U and Kruskal-Wallis tests were applied for non-normally distributed data. Linear regression analysis was employed to predict the individual innovativeness profiles of nursing students based on their attitudes towards scientific research and associated factors. ResultsAccording to the model created as a result of linear regression analysis, nursing students' attitudes towards scientific research and associated factors elucidate 22.9 % of the variance in individual innovativeness profiles. In this study, it was discerned that participants with elevated computer skills, a sense of competence in research conduct, a proclivity for engaging in scientific research, and a penchant for monitoring Turkish publications exhibited higher mean scores in the Individual Innovativeness Scale. ConclusionThis study established that nursing students' attitudes towards scientific research and associated factors possessed predictive capacity for individual innovativeness profiles.