You have accessJournal of UrologySexual Function/Dysfunction: Surgical Therapy I (PD20)1 Apr 2020PD20-03 ASSESSING THE SAFETY OF SURGICAL INTERVENTION DURING THE ACUTE PHASE OF PEYRONIE'S DISEASE Caleb Natale*, Hoang Minh Tue Nguyen, Joshua Pincus, Nicholas Ottaiano, Scott Brimley, Jacob Greenberg, Daniel Raza, Joseph Kim, Brian Dick, Ayad Yousif, Wayne Hellstrom, and Omer Raheem Caleb Natale*Caleb Natale* More articles by this author , Hoang Minh Tue NguyenHoang Minh Tue Nguyen More articles by this author , Joshua PincusJoshua Pincus More articles by this author , Nicholas OttaianoNicholas Ottaiano More articles by this author , Scott BrimleyScott Brimley More articles by this author , Jacob GreenbergJacob Greenberg More articles by this author , Daniel RazaDaniel Raza More articles by this author , Joseph KimJoseph Kim More articles by this author , Brian DickBrian Dick More articles by this author , Ayad YousifAyad Yousif More articles by this author , Wayne HellstromWayne Hellstrom More articles by this author , and Omer RaheemOmer Raheem More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000870.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Surgical corrective interventions during acute phase Peyronie's Disease (PD) are associated with increased perioperative complication. This study analyzes the outcomes of surgical intervention in patients with acute vs stable PD to assess safety of surgical intervention during the acute phase. METHODS: We retrospectively reviewed all patients who underwent surgical treatment of PD from June 2011 to June 2019 at our institution. Acute phase is defined as ≤12 months of penile curve plus pain; other cases were considered stable. Primary outcome measures were perioperative complications. RESULTS: A total of 178 patients underwent surgical intervention for acute and stable PD with a mean follow-up of 9.2 months. 38 patients (21.3%) were acute phase PD and 140 patients (78.7%) were in stable phase PD. No significant differences were noted in demographics and patients' characteristics including preoperative erectile function (IIEF) between two groups. Mean initial curvature was 57.5° in the acute group vs 57.2° in the stable groups (p=0.633), while mean international index of erectile function (IIEF) scores were 15.5 in the acute group and 14.2 in the stable group (p=0.320). Pain was reported by 34 (19.1%) stable phase patients pre-operatively. Most common procedure in both groups was IPP placement followed by plication, incision & grafting and excision. There were no significant differences between surgical procedures utilized for the two groups. Intraoperative complications were seen in 3 (7.9%) of acute PD cases compared to 2 (1.4%) of stable PD cases (p=0.039). Postoperative complications occurred in 17 (12.1%) stable PD patients vs 1 (2.6%) acute PD patient (p=0.094). Pain in the post-operative period was noted in 7 (18.4%) acute phase PD patients and 27 (19.3%) stable phase PD patients (p=0.905). CONCLUSIONS: This study demonstrates higher intraoperative complication rates in acute phase PD, however postoperative complication rates were similar between two groups. Our study suggests that surgical intervention in acute phase PD is safe with low perioperative complication rates. Further larger studies are prerequisite to elucidate the safety and efficacy of surgery in acute phase PD. Source of Funding: N/A © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e448-e448 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Caleb Natale* More articles by this author Hoang Minh Tue Nguyen More articles by this author Joshua Pincus More articles by this author Nicholas Ottaiano More articles by this author Scott Brimley More articles by this author Jacob Greenberg More articles by this author Daniel Raza More articles by this author Joseph Kim More articles by this author Brian Dick More articles by this author Ayad Yousif More articles by this author Wayne Hellstrom More articles by this author Omer Raheem More articles by this author Expand All Advertisement PDF downloadLoading ...