This paper presents numerical simulations of the deformation response of unsaturated embankments subjected to rainfall infiltration using a coupled hydro-mechanical constitutive model for unsaturated soils. The constitutive model accounts for the influence of degree of saturation on the stress–strain behavior and the influence of void ratio on the water retention behavior. The constitutive model was implemented in the finite difference program FLAC, calibrated using triaxial test data, and validated using measurements of wetting-induced deformations of embankment models from centrifuge tests. The validation demonstrates that the constitutive model can capture the coupled hydro-mechanical behavior of unsaturated soils under wetting conditions. Simulations of the hydro-mechanical response of unsaturated embankments subjected to rainfall infiltration indicate that the differential settlement across the top surface of the embankment between the centerline and shoulder increases significantly during rainfall infiltration, which could result in severe damage to overlying transportation infrastructure. As the rainfall infiltration increases, shear strains accumulate and form a potential failure surface at a shallow depth of approximately 2 m from the slope surface. Insights into the hydro-mechanical response of unsaturated embankments subjected to rainfall infiltration gained will be useful for considering climate change effects in design and construction of compacted embankments.