The growth of the processing industrial sector in Jambi province shows a decline, where the contribution of the industrial sector is quite worrying considering that the industrial sector is expected to play a role in encouraging economic growth, alleviating poverty, and creating jobs to reduce the high level of unemployment. Regional industrial development efforts mean that each region has superior commodities that illustrate the region's potential or ability to produce products, create added value, utilize resources, provide employment opportunities, generate income for the community and local government, and have prospects for increasing productivity and investment. The decline in contribution and the relatively small growth of industry must receive special attention from the government to encourage the industry again and prevent deindustrialization Jambi Province is the fourth largest rubber-producing region in the country, after South Sumatra, North Sumatra, and Riau. In 2021, land use in Jambi Province will still be dominated by plantation commodities with a contribution of 21.3 percent. Rubber production in Jambi will be 310 thousand tons in 2021. In 2021, the number of rubber farmers in Jambi Province will be 154,834 people, (National Leading Plantation Statistics, 2019-2021) this research aims to analyze the determinants of growth and development of the rubber processing industry subsector as a competitive agro-industry commodity for the regional economy of Jambi Province and to analyze the competitiveness of the rubber processing industry sub-sector as an agro-industry commodity for the regional economy of Jambi Province and its growth strategy. The analytical tools used to analyze the determinants of growth and development of the rubber processing industry subsector in the Jambi area are the Simultaneous Equation Model, Simple Regression, Revealed Comparative Advantage (RCA), and the Analytical Network Process (ANP) Method