Individual Approach Research Articles

HRTF individualization using ear images from 3D meshes

The head-related transfer function (HRTF) describes how a human receives sound from different directions in space. It is unique to each listener. The best way to obtain an individualized HRTF is through direct measurement, but it requires sophisticated laboratory equipment and long measurement times. This work proposes an approach for HRTF individualization employing ear images from 3D meshes using a deep neural network and spherical harmonics transform (SHT). The method relies on the HUTUBS dataset, including 3D meshes and HRTFs. The model uses ear images to predict a low-dimensional representation of the HRTF. Initially, ten images of the right ear of each 3D mesh are taken in different positions. The model consists of two main parts. The first is a convolutional neural network (CNN), which is used to extract features from the ear images. The second part learns from the feature map obtained and predict the spherical harmonic coefficients. Finally, the individualized HRTF is obtained through inverse SHT. The performance of the method is evaluated by computing the log-spectral distortion (LSD) between the measured HRTF and the predicted one. The results show favorable LSD values compared to other models addressing the same problem.

Measuring the individualization potential of treatment individualization rules: Application to rules built with a new parametric interaction model for parallel-group clinical trials.

For personalized medicine, we propose a general method of evaluating the potential performance of an individualized treatment rule in future clinical applications with new patients. We focus on rules that choose the most beneficial treatment for the patient out of two active (nonplacebo) treatments, which the clinician will prescribe regularly to the patient after the decision. We develop a measure of the individualization potential (IP) of a rule. The IP compares the expected effectiveness of the rule in a future clinical individualization setting versus the effectiveness of not trying individualization. We illustrate our evaluation method by explaining how to measure the IP of a useful type of individualized rules calculated through a new parametric interaction model of data from parallel-group clinical trials with continuous responses. Our interaction model implies a structural equation model we use to estimate the rule and its IP. We examine the IP both theoretically and with simulations when the estimated individualized rule is put into practice in new patients. Our individualization approach was superior to outcome-weighted machine learning according to simulations. We also show connections with crossover and N-of-1 trials. As a real data application, we estimate a rule for the individualization of treatments for diabetic macular edema and evaluate its IP.

Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks.

Spatial locations can be encoded and maintained in working memory using different representations and strategies. Fine-grained representations provide detailed stimulus information, but are cognitively demanding and prone to inexactness. The uncertainty in fine-grained representations can be compensated by the use of coarse, but robust categorical representations. In this study, we employed an individual differences approach to identify brain activity correlates of the use of fine-grained and categorical representations in spatial working memory. We combined data from six fMRI studies, resulting in a sample of 155 (77 women, 25 ± 5 years) healthy participants performing a spatial working memory task. Our results showed that individual differences in the use of spatial representations in working memory were associated with distinct patterns of brain activity. Higher precision of fine-grained representations was related to greater engagement of attentional and control brain systems throughout the task trial, and the stronger deactivation of the default network at the time of stimulus encoding. In contrast, the use of categorical representations was associated with lower default network activity during encoding and higher frontoparietal network activation during maintenance. These results may indicate a greater need for attentional resources and protection against interference for fine-grained compared to categorical representations.

Validity and reliability of motor competence assessment as an instrument measuring fundamental motor skills for 12-year-olds in Indonesia

The research aims to assess the validity and reliability of the Motor Competence Assessment (MCA) instrument for 12-year-olds. The validity and reliability test provides a comprehensive framework for objectively measuring motor competence and identifying areas for intervention to enhance motor skill development. The study included 321 participants (156 male and 165 fe-male) from diverse Indonesian elementary school backgrounds. Motor competence assessment involved six test components, each conducted with two trials. Validity was assessed through exploratory factor analysis (EFA), and reliability was assessed via Cronbach's alpha, with raw data converted to a scale for EFA. The Kaiser-Meyer-Olkin (KMO) & Bartlett Test results and the Sampling Ade-quacy (MSA) measure are suitable for running EFA because they show more than 0.50. The standards for each item were met in the Communalities test by showing an extraction of >0.50 for each item. The MCA instrument proved valid because each test item (variable) firmly attaches to one instrument. Reliability tests, using Cronbach's Alpha, show that MCA instruments are reliable and usable. The Motor Competence Assessment (MCA) instrument demonstrates validity and reliability in measuring motor skills. Ex-ploratory factor analysis (EFA) identifies two main components: locomotor skills and stability and manipulative motor skills. Cronbach's alpha further confirms MCA's reliability. Its effectiveness in various contexts, including physical education and rehabilitation, supports targeted interventions. Understanding motor skill development with MCA enhances tailored approaches for individu-als, promoting physical well-being and performance. Keywords: physical education, motor skill, elementary school, assessment.

Toxic relationship in youth communication through self-love intervention strategy

This study set out to identify and analyze toxic relationships in interpersonal communication among adolescents. The toxic relationship, as an unhealthy relationship, does have an impact on the occurrence of internal conflicts. Such relationships often cause the people involved to encounter unproductiveness and mental disorders, which can trigger an emotional outburst that leads to violence. A qualitative approach was used as the research method. The data collection techniques comprised FGD, observation, and in-depth interviews with informants/participants as primary data. The study findings show that first, the perpetrators of toxic relationships, namely toxic people, could be those closest to the victims, such as the nuclear family (father, mother, and siblings). In addition, the perpetrator could be a lover in an unhealthy romantic relationship or peers and even friends who often do the bullying via verbal, physical, or even sexual violence. Second, toxic relationships can be categorized into several forms, namely unhealthy relationships with friends (‘toxic friendship’), parents/family (‘toxic parenting’), lovers, and cheating parents, which can affect a child’s mentality. Actions necessary include the raising of awareness and concern for the community. If violent behavior occurs, it is not permissible to act permissive. The individual approach carried out during victim assistance can entail consultations in the form of ‘vent sessions’. A powerful way to anticipate being trapped in an unhealthy relationship is via self-love. Counselling is carried out with a self-healing approach to restore victims’ self-confidence and maintain their mental health.

STRATEGIES FOR INDIVIDUALIZING LEARNING AS A MEANS OF CREATING A BARRIER-FREE EDUCATIONAL ENVIRONMENT

Strategies for individualizing learning are an important and effective means of creating a barrier-free educational environment that takes into account the diverse needs, abilities and interests of each student. The purpose of the study was to characterize strategies for individualizing learning as a means of creating a barrier-free educational environment. The following strategies for individualizing learning are characterized: the use of differentiation of tasks and materials, the creation of different levels of tasks and access to materials for each student of secondary education; partnership with parents and the community; systematic assessment and monitoring of students' academic achievements, adaptation of the educational process to maximize the personal potential of each secondary education student; creation of an individual curriculum as a means of creating a barrier-free educational environment. It is emphasized that individualization of learning contributes to the development of each student, the use of individual approaches allows each student to advance in learning, taking into account their needs, pace of development and learning style. It is indicated that the creation of individualized curricula and assignments promotes the rapprochement of teacher and student, strengthens interaction and contributes to the positive development of the pedagogical process. It is emphasized that the use of strategies for individualizing learning is an important step in creating a barrier-free educational environment that promotes successful learning and development of each student. The strategies considered include differentiation of tasks and teaching methods, interactive technologies, individual curricula and other approaches aimed at taking into account the needs and abilities of each student. It is shown that the successful implementation of these strategies contributes to the creation of an environment in which every student has the opportunity to achieve their full potential, and barrier-free education becomes a reality in the educational process. It has been found that individualization of learning is an acceptor for creating a barrier-free educational environment where every student has the opportunity to access education and development in accordance with their needs and capabilities. It is concluded that strategies for individualizing learning are a key tool in creating a barrier-free educational environment that meets the needs of all students and contributes to their successful learning and development.

Implementation of an Interdepartmental Model of Complex Rehabilitation in the Perm Region in a Specialized Centre

BACKGROUND: Contemporary Russian system of complex rehabilitation and habilitation of disabled people is in the process of transformation. Application of the biopsychosocial approach through the use of the International Classification of Functioning, Disability and Health as a planning methodology Implementation and evaluation of rehabilitation measures make it possible to implement the key principles of rehabilitation: earlier, comprehensiveness, continuity, individual approach.
 AIM: To substantiate the possibility of implementing a modern regional interdepartmental model of integrated rehabilitation in a specialized centre, taking into account the structure of disability and the formation of new target rehabilitation groups.
 MATERIALS AND METHODS: Analysis of the dynamics of primary disability of the adult population, description of the structural and functional model of the creation and operation of a multidisciplinary rehabilitation center in conditions of interdepartmental cooperation.
 RESULTS: The structure of primary and secondary disability in the Perm Region is characterized by the predominance of persons with disabilities of groups 1 and 2 (60%) of working age, whose disability is caused in 30% of cases by malignant neoplasms. This determines the content of individual rehabilitation and habilitation programs to be developed for persons with disabilities and should be reflected in the development of appropriate infrastructure in the region. Modernization of the whole system, involving the use of targeted rehabilitation groups, ensuring continuity of medical and social activities in the relevant organizations and creating conditions for their continuation in the place of residence, should contribute to the effectiveness of rehabilitation activities in general.
 CONCLUSION: Recommendations on improvement of the system of complex rehabilitation in the conditions of a specialized center on the basis of interdepartmental cooperation have been proposed as a result of the research.

Occupational Perceptions of Undergraduate College Students Using Q-Methodology

A successful transition into adulthood is marked by occupational identity. From the developmental perspective, it is vital to examine the occupational perceptions of college students who grew up in distinct social and psychological environments from previous generations. To bridge the research gap, this study is to examine college students’ subjective occupational perceptions and the psychosocial factors impacting their views on occupational identity. Fifty college students sorted 72 Q statements about their viewpoints on occupations. Findings revealed four viewpoints on the occupational perceptions with the highly work-engaged; money-minded; intrinsic motivation for career choice; and parent-child conflict. A person-centered counseling approach for individuals experiencing financial difficulties and/or parental conflict could enhance a sense of achievement and occupational identity. Considering delayed developmental tasks and uncertainties about their future career, along with their internal motivation and external conditions, comprehensive educational programs would be beneficial in exploring diverse career choices.

Augmentative and alternative communication: the experience of Malaysian speech-language pathologists and caregivers of individuals with aphasia

ABSTRACT Background Augmentative and Alternative Communication (AAC) serves as a compensatory intervention approach for individuals with aphasia and is often introduced by speech-language pathologists (SLPs) after outcomes from restorative approaches plateau. Communication partners (i.e., caregivers) have a pivotal role in ensuring the successful use of AAC by adults with aphasia. Despite there being a large body of research on the use of AAC by adults with aphasia little is known about the experience of caregivers of individuals with aphasia who use AAC in supporting its use. Aims This study conducted in Malaysia was aimed to (a) explore the practices of Malaysian SLPs when introducing AAC to adults with acquired communication disorders (ACD) including aphasia and (b) describe the experience of caregivers regarding the use of AAC by adults with aphasia under their care. Method & Procedures This mixed-methods study had two phases. In Phase 1, a survey was distributed to 200 SLPs throughout Malaysia. Thirty-seven SLPs who met the inclusion criteria of having a caseload of more than 80% adults and at least 20% adults with aphasia responded to the survey and provided information about their use of AAC. For Phase 2, eight caregivers of adults with aphasia who had been introduced to AAC were interviewed to obtain information about their experience using AAC. Outcomes & Results Findings from Phase 1 indicated that Malaysian SLPs most often introduced unaided and low-tech AAC to adults with ACD (including aphasia). Most of them felt that they lacked knowledge and skills in the provision of AAC services to adults and hoped for more training. Three themes emerged from the qualitative content analysis conducted on interview transcripts from Phase 2: (a) the positive impact of the use of AAC, (b) challenges faced when using AAC, and (c) hopes for the future. The findings of this study suggest that both SLPs and caregivers recognize the importance of AAC for adults with ACD including aphasia and need to work together closely to promote inclusion of adults with aphasia who use AAC and acceptance of AAC as a form of aphasia rehabilitation.

Accurate preoperative prediction of nodal metastasis in papillary thyroid microcarcinoma: Towards optimal management of patients.

To enhance the accuracy in predicting lymph node metastasis (LNM) preoperatively in patients with papillary thyroid microcarcinoma (PTMC), refining the "low-risk" classification for tailored treatment strategies. This study involves the development and validation of a predictive model using a cohort of 1004 patients with PTMC undergoing thyroidectomy along with central neck dissection. The data was divided into a training cohort (n = 702) and a validation cohort (n = 302). Multivariate logistic regression identified independent LNM predictors in PTMC, leading to the construction of a predictive nomogram model. The model's performance was assessed through ROC analysis, calibration curve analysis, and decision curve analysis. Identified LNM predictors in PTMC included age, tumor maximum diameter, nodule-capsule distance, capsular contact length, bilateral suspicious lesions, absence of the lymphatic hilum, microcalcification, and sex. Especially, tumors larger than 7 mm, nodules closer to the capsule (less than 3 mm), and longer capsular contact lengths (more than 1 mm) showed higher LNM rates. The model exhibited AUCs of 0.733 and 0.771 in the training and validation cohorts respectively, alongside superior calibration and clinical utility. This study proposes and substantiates a preoperative predictive model for LNM in patients with PTMC, honing the precision of "low-risk" categorization. This model furnishes clinicians with an invaluable tool for individualized treatment approach, ensuring better management of patients who might be proposed observation or ablative options in the absence of such predictive information.

Advantages of spinal compared to general anesthesia

Spinal anesthesia is a regional anesthesia technique achieved by a local subarachnoid anesthetic injection. Local anesthetic blocks conduct of pain on the spinal level and provides analgesia of the body below the navel. It can be used in a wide array of procedures, including laparoscopy. Inguinal hernia surgery is performed under general or regional anesthesia, depending on the indications and the individual approach of the anesthetist and surgeon. This article brings review of the literature and our experience in advantages and disadvantages of spinal anesthesia in open inguinal hernia surgery. We find that spinal anesthesia is cost effective and has advantages in inguinal hernia surgery when compared with general anesthesia, in terms of better postoperative pain control, and less nausea and vomiting, with minimal effects on hemodynamic stability.

Degradation of Procion brilliant yellow H-E6G using ultrasonic and hydrodynamic cavitation combined with oxidants with demonstration at pilot scale.

The current study focuses on the degradation of Procion brilliant yellow H-E6G, an azo dye, using ultrasonic and hydrodynamic cavitation (HC), evaluating the impact of various parameters on the extent of degradation. The use of only ultrasound showed less oxidation capacity as indicated by only 19.1% degradation at an optimized power of 140 W, pH of 2.5, temperature of 40°C, and initial dye concentration of 15 ppm. The effectiveness of hybrid approaches involving US + H2 O2 , US + Fenton, and US + H2 O2 + potassium persulfate (KPS) was subsequently evaluated under optimized conditions. A notable enhancement in decolorization extent was observed for combined operations, including US + H2 O2 , US + Fenton, and US + H2 O2 + KPS (dual oxidant scheme) with the actual decolorization extents as 80.6%, 85%, and 92.2% respectively. An optimized scheme of US + H2 O2 + KPS was also utilized to decolorize the dye at a pilot scale using a US flow cell and also an HC reactor that yielded 91.8% and 88% reductions in initial concentration. The dye decolorization was elucidated to follow first-order kinetics for all the individual and combination approaches. The obtained values of the rate constants were also utilized for the evaluation of the synergistic index. A toxicity analysis was also performed on the dye, both before and following treatment, utilizing two bacterial strains. A comparative analysis of various treatment approaches has been presented focusing on factors such as cavitational yield, operational expenses, and energy requirements. The study elucidated that the combination of US + H2 O2 + KPS effectively removes Procion brilliant yellow H-E6G giving 92.2% as the maximum degradation at an operating cost of 0.1862 $/L. PRACTITIONER POINTS: First depiction of cavitative degradation of Procion brilliant yellow H-E6G Optimizing the equipment operating parameters and chemical oxidants Demonstration of optimized treatment scheme at pilot scale Evaluation of various approaches based on synergy and costs of treatment US + H2 O2 + KPS is the best approach for dye degradation.

Decompensation of Heart Failure in "Fragile" Patients: Clinical Features and Approaches to Therapy

To evaluate the impact of frailty syndrome (FS) on the course of acute decompensated heart failure (ADHF) and the quality of drug therapy before discharge from the hospital in patients with reduced and moderately reduced left ventricular ejection fraction (LVEF). This open prospective study included 101 patients older than 75 years with reduced and mid-range LVEF hospitalized for decompensated chronic heart failure (CHF). FS was detected during the outpatient follow-up and identified using the Age is Not a Hindrance questionnaire, the chair rise test, and the One Leg Test. The "fragile" group consisted of 54 patients and the group without FS included 47 patients. Clinical characteristics of patients were compared, and the prescribing rate of the main drugs for the treatment of CHF was assessed upon admission to the hospital. The sacubitril/valsartan or dapagliflozin therapy was initiated in the hospital; prescribing rate of the quadruple therapy was assessed upon discharge from the hospital. Patients with reduced LVEF were followed up for 30 days, and LVEF was re-evaluated to reveal possible improvement due to optimization of therapy during hospitalization. Statistical analysis was performed with the SPSS 23.0 software. The main causes for decompensation did not differ in patients of the compared groups. According to the correlation analysis, FS was associated with anemia (r=0.154; p=0.035), heart rate ≥90 bpm (r=0.185; p=0.020), shortness of breath at rest (r =0.224; p=0.002), moist rales in the lungs (r=0.153; p=0.036), ascites (r=0.223; p=0.002), increased levels of the N-terminal pro-brain natriuretic peptide (NT-proBNP) (r= 0.316; p<0.001), hemoglobin concentration <120 g / l (r=0.183; p=0.012), and total protein <65 g / l (r=0.153; p=0.035) as measured by lab blood tests. Among patients with LVEF ≤40 % in the FS group (n=33) and without FS (n=33), the quadruple therapy was a part of the treatment regimen at discharge from the hospital in 27.3 and 3.0 % of patients, respectively (p=0.006). According to the 30-day follow-up data, improvement of LVEF was detected in 18.2% of patients with LVEF ≤40% in the FS group and 12.1% of patients with LVEF ≤40% in the FS-free group (p=0.020). In patients with LVEF 41-49 % in the FS (n=21) and FS-free (n=14) groups, the prescribing rate of the optimal therapy, including sacubitril/valsartan, sodium-glucose cotransporter 2 inhibitors, beta-blockers, and mineralocorticoid receptor antagonists, no statistically significant differences were detected (14.3 and 7.1 %, respectively; p=0.515) at discharge from the hospital. Patients with ADHF and FS showed more pronounced clinical manifestations of decompensation, anemia, heart rate ≥90 beats/min, and higher levels of NT-proBNP upon admission. The inpatient therapy with sacubitril/valsartan or dapagliflozin was more intensively initiated in FS patients with reduced LVEF. An individualized approach contributed to achieving a prescribing rate of sacubitril/valsartan of 39.4%, dapagliflozin of 39.4%, and quadruple therapy of 27.3% upon discharge from the hospital.

Dental Care for Cancer Patients in the Prevention of Complications of Chemotherapy and Head and Neck Radiation Therapy

Oncological diseases occupy one of the first places in the structure of disability and mortality of the population. The main methods of treating patients with malignant tumors in the maxillofacial area are surgical method, radiation therapy and chemotherapy. Treatment with only one of the listed methods It is rarely performed, mainly at the stage of cancer in situ or stage I of the disease. The treatment depends on the clinical and morphological characteristics of the tumor and requires the use of all methods simultaneously or in a certain sequence. Radiation and chemotherapy treatments not only have systemic side effects, but also side effects in the treatment area. Against the background of antitumor treatment, there is an exacerbation of concomitant chronic diseases, including odontogenic ones. Pathological changes appear on the mucous membrane oral cavity, on the skin, in the subcutaneous tissue, in the salivary glands and in the bone marrow of the jaw bones. The degree of damage to these structures during tumor treatment depends on their initial condition. At the same time, the initial condition of the oral cavity affects the quality of antitumor treatment. Poor oral hygiene and chronic odontogenic lesions can cause the development of episodic fevers and other general complications. All this requires stopping or changes in the tactics of antitumor treatment, which reduces its radicalism. It becomes obvious that sanitation of the oral cavity, carried out before treatment by an oncologist, will avoid or reduce the frequency complications in the maxillofacial area, improve the quality of life of an oncology patient. Dental care for such a patient has features and requires an individual approach. The purpose of this study was to review the literature on the main oral tissue complications arising from chemotherapy and radiation therapy in the head and neck region. In Google Scholar, Medline, Scopus, Web of Sciences, PubMed a systematic review was conducted. Search keywords terms included head and neck cancer, dental care, prevention of complications of cancer, oral tissue lesions manifestationin, chemotherapy, head and neck radiation therapy. Conducted a preliminary search and reviewed 132 titles and abstracts in this literary review included 48 article. This article analyzes the main complications of oral tissues resulting from chemotherapy and radiation therapy in the head and neck area and provides practical recommendations for the management and prevention of complications in this category of patients.

Cross-country analysis of contextual factors and implementation strategies in under-5 mortality reduction in six low- and middle-income countries 2000-2015.

The Exemplars in Under-5 Mortality (U5M) was a multiple cases study of how six low- and middle-income countries (LMICs), Bangladesh, Ethiopia, Nepal, Peru, Rwanda, and Senegal, implemented health system-delivered evidence-based interventions (EBIs) to reduce U5M between 2000 and 2015 more effectively than others in their regions or with similar economic growth. Using implementation research, we conducted a cross-country analysis to compare decision-making pathways for how these countries chose, implemented, and adapted strategies for health system-delivered EBIs that mitigated or leveraged contextual factors to improve implementation outcomes in reducing amenable U5M. The cross-country analysis was based on the hybrid mixed methods implementation research framework used to inform the country case studies. The framework included a common pathway of Exploration, Preparation, Implementation, Adaptation, andSustainment (EPIAS). From the existing case studies, we extracted contextual factors which were barriers, facilitators, or determinants of strategic decisions; strategies to implement EBIs; and implementation outcomes including acceptability and coverage. We identified common factors and strategies shared by countries, and individual approaches used by countries reflecting differences in contextual factors and goals. We found the six countries implemented many of the same EBIs, often using similar strategies with adaptations to local context and disease burden. Common implementation strategies included use of data by decision-makers to identify problems and prioritize EBIs, determine implementation strategies and their adaptation, and measure outcomes; leveraging existing primary healthcare systems; and community and stakeholder engagement. We also found common facilitators included culture of donor and partner coordination and culture and capacity of data use, while common barriers included geography and culture and beliefs. We found evidence for achieving implementation outcomes in many countries and EBIs including acceptability, coverage, equity, and sustainability. We found all six countries used a common pathway to implementation with a number of strategies common across EBIs and countries which contributed to progress, either despite contextual barriers or by leveraging facilitators. The transferable knowledge from this cross-country study can be used by other countries to more effectively implement EBIs known to reduce amenable U5M and contribute to strengthening health system delivery now and in the future.

Clinical Indicators of Bone Deterioration in Alcoholic Liver Cirrhosis and Chronic Alcohol Abuse: Looking beyond Bone Fracture Occurrence.

Although previous studies indicated that chronic alcohol abuse (CAA) and alcoholic liver cirrhosis (ALC) are associated with increased bone fragility, understanding bone fragility determinants is still modest in these individuals. We used a comprehensive individualized clinical fracture risk assessment approach (vertebral osteodensitometry, femoral osteodensitometry and geometry, and serum bone turnover biomarkers) to compare adult male patients with ALC who have not previously had femoral or vertebral fractures (n = 39), patients with CAA (without liver cirrhosis, n = 78) who have not previously had femoral or vertebral fractures and healthy age- and sex-matched controls (n = 43). Our data suggested that intertrochanteric bone mineral density was significantly lower in ALC and CAA patients than in controls. Also, the trabecular bone score was considerably lower in ALC patients compared with CAA and control individuals. The most significant inter-group differences in femoral geometry were noted on the femoral shaft. Patients with ALC and CAA have a higher 10-year risk of major osteoporotic fractures compared to the controls. Analysis of bone turnover biomarkers showed increased osteoprotegerin and beta-C-terminal telopeptide serum concentrations and decreased insulin growth factor-1 concentrations in patients with ALC compared to CAA and control groups. Our data revealed that bone alterations are present in patients with ALC and CAA even if they did not sustain a nontraumatic bone fracture, but it is also indicative that current bone-assessing clinical methods are not entirely reliable. Thus, future studies should focus on developing a reliable integrative clinical tool that can be used to accurately predict and prevent bone fracture occurrences in patients with ALC and CAA.

Индивидуально-типологические детерминанты конфликтологической компетентности сотрудников полиции

The relevance of the study is due to the high level of conflict in the professional activities of police officers and insufficient development of the issue of conflictological competence in the context of the individual typological approach. In the article the author discusses conflictological competence as a specific type of professional competence. The psychological content and scheme of the research analysis of the components of conflicto-logical competence of the police officers are revealed. The indicators of conflictological competence / incom-petence for reflexive-evaluative, emotional-volitional, motivational-value and behavioral components are rec-orded. The severity of the police officers’s of individual typological characteristics has been analyzed. Negative characteristics provoking manifestations of conflictological incompetence of police officers by type of character accentuations (hyperthymic and emotive), which are expressed at the level of tendency or have a high degree of representation, are considered. Based on the results of the correlation analysis, it is shown that conflictologi-cal competencies are represented to varying degrees among police officers, taking into account their individual typological characteristics.

Применение Chat GPT для создания учебных материалов по английскому языку для детей младшего школьного возраста

Nowadays there is a tendency of implementing artificial intelligence in various fields, including education. Lan-guage models, including Chat GPT, are mainly used for working with such monotonous tasks as checking homework, writing and assessment tasks. The implementation of AI has certain advantages (finding individual approach, fast and detailed feedback, etc.) and disadvantages (overdependence on the technology, academic cheating, etc.). This article examines the use of the above language system for generating English grammar exercises in order to introduce them into the educational process when working with primary school students in comparison with the use of similar material from traditional grammar books. The study revealed the absence of significant differences between exercises from grammar books and those created by the artificial intelligence.

Nursing diagnoses in patients with COVID-19 admitted to the intensive care unit: CROSS-MAPPING

ObjectiveTo identify and analyze the nursing diagnoses listed in the medical records of COVID-19 patients admitted to an intensive care unit using Taxonomy II of NANDA-I. Background: COVID-19 is a complex disease with heterogeneous behaviors, and the role of intensive care nurses in accurately identifying related signs and symptoms has become even more critical during the pandemic. Nurses rely on classification systems or taxonomies to standardize concepts and language in practice. Method: This quantitative study employed a descriptive and individual approach, utilizing the cross-mapping method. Data were collected from 57 medical records of critical care patients in a hospital in northeastern Brazil between July 2020 and March 2021. Three researchers analyzed the mapped diagnoses, and agreement was assessed using the Content Validation Index and Fleiss' Kappa. Results: Among the listed nursing diagnoses, 54.28% were found to be standardized, 45.71% had corresponding nursing diagnoses, and 5.71% did not have an equivalent diagnosis in the reference taxonomy used in the study. Due to the possibility of multiple nursing diagnoses in the same patient, the most frequent diagnoses were Risk of pressure injury in adults (66.66%), Risk of falls in adults (64.91%), and Risk of infection (45.61%). Among the 37 diagnoses mapped, the risk diagnoses were the most prevalent and could be prevented if identified early. Conclusions: The study highlights the importance of standardized nursing diagnoses in the ICU for COVID-19 patients and the need for accurate identification and prevention of risk diagnoses to enhance patient care and improve outcomes.

Sequential Co-Immobilization of Enzymes on Magnetic Nanoparticles for Efficient l-Xylulose Production.

Multi-enzymatic strategies have shown improvement in bioconversion during cofactor regeneration. In this study, purified l-arabinitol 4-dehydrogenase (LAD) and nicotinamide adenine dinucleotide oxidase (Nox) were immobilized via individual, mixed, and sequential co-immobilization approaches on magnetic nanoparticles, and were evaluated to enhance the conversion of l-arabinitol to l-xylulose. Initially, the immobilization of LAD or Nox on the nanoparticles resulted in a maximum immobilization yield and relative activity of 91.4% and 98.8%, respectively. The immobilized enzymes showed better pH and temperature profiles than the corresponding free enzymes. Furthermore, co-immobilization of these enzymes via mixed and sequential methods resulted in high loadings of 114 and 122 mg/g of support, respectively. Sequential co-immobilization of these enzymes proved more beneficial for higher conversion than mixed co-immobilization because of better retaining Nox residual activity. Sequentially co-immobilized enzymes showed a high relative conversion yield with broader pH, temperature, and storage stability profiles than the controls, along with high reusability. To the best of our knowledge, this is the first report on the mixed or sequential co-immobilization of LAD and Nox on magnetic nanoparticles for l-xylulose production. This finding suggests that selecting a sequential co-immobilization strategy is more beneficial than using individual or mixed co-immobilized enzymes on magnetic nanoparticles for enhancing conversion applications.