Indicators Of Physical Development Research Articles

Association of body index with fecal microbiome in children cohorts with ethnic-geographic factor interaction: accurately using a Bayesian zero-inflated negative binomial regression model.

The microbiome is closely associated with physical indicators of the body, such as height, weight, age and BMI, which can be used as measures of human health. Accurately identifying which taxa in the microbiome are closely related to indicators of physical development is valuable as microbial markers of regional child growth trajectory. Zero-inflated negative binomial (ZINB) model, a type of Bayesian generalized linear model, can be effectively modeled in complex biological systems. We present an innovative ZINB regression model that is capable of identifying differentially abundant taxa associated with distinctive host phenotypes and quantifying the effects of covariates on these taxa, and demonstrate that its accuracy is superior to traditional Hurdle and INLA models. Our pipeline of integrating bacterial differential abundance in microbiome data and relevant covariates is effective and feasible.

Гігієнічна оцінка фізичного розвитку дітей і підлітків – один із напрямів наукової діяльності кафедри загальної гігієни з екологією Львівського національного медичного університету імені Данила Галицького (до 125-річчя створення кафедри)

Objective is to highlight the results of scientific research on the hygienic assessment of the physical development of children and adolescents performed at the Department of General Hygiene and Ecology of Danylo Halytsky Lviv National Medical University Materials and methods. Printed scientific works, abstracts, scientific research reports. Methods – search, analytical, descriptive. Results. 125 years have passed since the founding of the Department of General Hygiene and Ecology of Danylo Halytsky Lviv National Medical University. Hygienic assessment of the physical development of children and adolescents has become one of the important directions of scientific activity of the department. In the late 40s of the twentieth century, the physical development of students of craft and factory colleges, factory training schools, and young men and women who worked at manufacturing enterprises was studied. It was found that young men and women who worked had better indicators of physical development. Their anthropometric indicators significantly exceeded those of peers in 1923. The physical development of boys and girls aged 4-6 in Lviv was studied in 1995-1996, in rural areas of Lviv region – in 1998-1999. It was found that 71.2%-71.6% of preschoolers had normal physical development. In particular, 72.4% of boys and 70.0% of girls who were residents of the city, 70.6% of boys and 72.6% of girls who were residents of rural areas. Deficits of body weight of the first degree were found in 38.7%, excess body weight of the first degree in 29.9% of children from Lviv, and among children from rural areas – 34.6% and 32.8% respectively. Rural children were shorter and had a lower body weight than urban children. From 1969-1971 until 1995-1996, urban children's body weight decreased by 1 kg on average. Among the examined male and female primary school students (2003-2005), 73.5% had normal physical development at entering school, 67.8% in the second grade, and 66.2% in the third grade. The number of individuals with tall height and excess body weight of the I and II degrees has increased. According to the retrospective analysis of anthropometric parameters compared to 1969-1971 a tendency to deceleration was revealed. Among the examined schoolboys and schoolgirls in 2014-2015 68.9% of 7-year-olds, 64.1% of 8-year-olds, 70.5% of 9-year-olds and 68.7% of 10-year-olds had an average height, harmonious development among 7-year-old boys amounted to 69, 8%, girls – 66.1%, 8-year-olds – 65.9% and 64.6%, 9-year-olds – 72.6% and 65.8%, respectively, 10-year-old boys had the smallest share of harmonious physical development – 50.6%, and girls – 59.4%. Dynamics of anthropometric indicators from 1967-1969 to 2014-2015 was characterized by processes of acceleration against the background of astenization and gracefulization of children. Growth processes of anthropometric indicators took place unevenly. The lowest indicators of height and body weight in children were observed from 1992 to 1996, the highest – in 2014-2015. Nowadays children are taller and have more body weight than their peers 19-49 years ago. Among the examined schoolboys and schoolgirls of secondary school age (2018-2020), 74.5% and 77.3% of average height were found, respectively, 53.7% of schoolboys and 58.5% of 11-year-old schoolgirls had harmonious development, 12-year-olds – 60.5% and 56.3%, respectively, 14-year-olds – the share of harmonious development amounted to 79.3%. 16.5% of 11-year-old boys and 15.4% of girls, 11.4% and 16.9% of 12-year-olds, 19.6% and 16.0% of 14-year-old schoolchildren were overweight. Disharmonious physical development of schoolchildren is caused by an excess or deficit of body weight of the I and II degrees, an increase or decrease in the circumference of the chest of the I and II degrees, and their combinations. The dynamics of the physical development of schoolboys and schoolgirls is characterized by processes of acceleration – a clear regularity of the increase in height and body weight of children from 1996 to 2020 has been traced. Territorial peculiarities of physical development have been revealed. Regional scales of regression by height were developed. Conclusions. The majority of the surveyed children and adolescents have harmonious physical development. At the present stage, the processes of acceleration of physical development have been identified. To assess the physical development of preschoolers, primary and secondary schoolchildren, regional regression scales by height were developed. Keywords. Department of general hygiene with ecology, physical development, boys, girls, schoolboys, schoolgirls.

Behavioral, Social, and Emotional Development of Five-Year-Old Children Conceived by Assistive Reproductive Technologies (In-Vitro Fertilization)

Preschool children conceived through In-Vitro Fertilization (IVF) tend to demonstrate particular behavioral, social, and emotional patterns that correlate with their physical development. The authors used a number of techniques to assess the behavior and social and emotional development of five-year-old IVF children. Such questionnaires as Your Child’s Behavior and Child’s Relationship with Friends and Family cast light on the behavioral, social, and emotional status. To define the physical development, the authors used such questionnaires as Child Feeding Issues, Three-Month History of Infectious Diseases, History of Injuries and Accidents, and Chronic Disease History. The sample consisted of 81 IVF children and 153 naturally-conceived children (aged 5); it included subgroups of children with perinatal developmental risks. Most parents of the IVF children reported neither behavioral nor social issues. However, the IVF children demonstrated more severe emotional issues. The IVF children with perinatal developmental risks had more pronounced emotional and anxiety issues, which was not typical of naturally-conceived children with perinatal risks. Both groups included children with difficulties in social and emotional development. The study revealed four significant factors that defined the difficulties of the socio-emotional development in the IVF children: behavioral disorders, aggression, social issues, and emotional issues. The significant correlations of behavioral, social, and emotional development in the IVF group indicated some specificity against the control. The correlating indicators of mental and physical development proved that physical development might affect behavioral, social, and emotional development in IVF children.

Clinical case of a live-born child with triploidy

Theoretical data on etiopathogenesis, clinical manifestations of triploidy, life expectancy of children in case of live-birth with this chromosomal anomaly are presented. A clinical case of a triploidy in a child is described. The girl was born from the first pregnancy from young healthy parents. Parents are not close relatives. Pregnancy was complicated with anemia, recurrent threats of miscarriage, progressive lack of water, progressive violation of uteroplacental blood flow and delay in fetal development. A congenital heart defect was diagnosed prenatally. The girl was born at 38 weeks of pregnancy with low indicators of physical development by caesarean section. Multiple developmental anomalies and malformations were revealed after birth. Combined congenital heart disease was confirmed by instrumental examination. Karyotyping revealed karyotype 69, ХХХ. Dynamic observation revealed that the child's age-related skills were not formed. Epileptic seizures occurred from the age of 4 months. The seizures had a status course. Surgical correction of congenital heart disease was performed in two stages: at 4.5 months and at 9.5 months in this patient. A fatal outcome occurred with an increase in multiple organ failure at the age of 10 months. The features of the clinical case, the possibilities of prenatal diagnosis of triploidy are analyzed.

Morphometric correlates of the physical development structure of combat athletes in the process of ensuring special work capacity

Background and Study Aim. Despite extensive training, combat athletes often face challenges in optimizing their physical development to enhance performance and work capacity. This study aims to examine the interrelations of key parameters within the physical development (PD) structure of highly skilled combat athletes in the process of ensuring special work capacity. Material and Methods. Between 30 and 83 wrestlers of different weight categories and skill levels, all members of the national teams of Ukraine in freestyle and Greco-Roman wrestling, and judo, participated in various studies. The age of the subjects ranged from 18 to 31 years. The combat athletes aged 18-24 years old were students of Ukrainian universities. A total of 56 indices of PD, speed-strength fitness, and special work capacity of the combat athletes were registered. The special work capacity of wrestlers was estimated based on the intensity of performing 15 specialized throws of a partner of equal weight in 3 series. Each series of throws was performed 3 times, with a rest interval of 1 minute between the series. Results. The studies revealed that in the morphometric component of combat athlete PD structure, the circumference dimensions of the body are more integrated compared to the longitudinal, transverse, anteroposterior dimensions, and other parameters. The most highly interconnected circumferences are those of the neck, thorax, relaxed and tensed shoulder, forearm, hip, and shin. These parameters show the highest correlation with both the athletes' skill level and the integral parameters of PD, such as body weight, surface area, weight category, and Quetelet index. An increase in wrestlers' skill level is associated with an increase in the neck, chest, shoulder, and hip circumferences. It also correlates with the enhancement of anaerobic work capacity and the formation of the morphofunctional profile of highly skilled combat athletes. Multiple regression models reflecting these dependencies were developed. Conclusions. The thorax, thigh, shoulder, and neck circumferences are key parameters of the morphometric component of combat athlete PD structure. They are the most integrated into the general structure of physical fitness and determine the integral parameters of PD, the level of anaerobic work capacity, and the strength endurance of wrestlers with a high degree of accuracy. The specificity of improving PD structure and special fitness of combat athletes is manifested in the fact that, as the athlete's skill level increases, the volumes of the thorax, neck, shoulder, and thigh increase to the greatest extent. Their interrelations among themselves, with the integral parameters of PD, and with the level of anaerobic work capacity, speed, and speed-strength endurance tend to enhance. The developed models can be used for predicting the PD structure of combat athletes of different skill levels and weight categories. They can also be utilized for assessing special work capacity and designing appropriate normative evaluation scales.

Vitamin D Sufficiency and Its Relationship with Indicators of Physical Development and the State of Bone Tissue in Cadets of a Military Higher Educational Institution

Vitamin D Sufficiency and Its Relationship with Indicators of Physical Development and the State of Bone Tissue in Cadets of a Military Higher Educational Institution

Homocysteine as a biomarker of physical activity and exercise tolerance in adolescent children

Purpose: To determine the homocysteine content in children and adolescents with different levels of physical activity, to establish the relationship between homocysteine content, indicators of physical development, level of physical activity and tolerance to physical activity in adolescence. Material and Methods. We examined 83 children aged 11 to 17 years, who were examined by a pediatrician, an endocrinologist, and the girls by a pediatric gynecologist. The study was conducted in accordance with the principles of the Declaration of Helsinki and approved by the Committee on Bioethics and Deontology. Height, body weight and body mass index were assessed; physical activity tolerance by the Ruffier test; physical activity was assessed using a questionnaire; serum homocysteine was determined by enzyme-linked immunosorbent assay. Results. 81% of adolescents with high physical activity had regular sports training at least three times a week. In the group with low physical fitness, only 25.6 % attended sports sections, and 44.2 % of adolescents were completely physically inactive. The level of homocysteine in the blood did not depend on the sex of adolescents and physical development. Moderate hyperhomocysteinemia was detected in 41 adolescents, 68.3 % of whom had poor and low exercise tolerance and/or low physical activity. Statistically significantly higher homocysteine levels were observed in children with low physical activity (p<0.05), those who did not have sports training (p=0.027) or had reduced adaptation to physical activity (p<0.01). Conclusions. The level of homocysteine in the blood serum of adolescents did not depend on gender, physical development and the presence of somatic pathology. Low physical activity of adolescents is accompanied by increased levels of homocysteine in the blood. On the contrary, adolescents with high physical activity have lower levels. The lowest levels of homocysteine are observed in adolescents with good to excellent exercise tolerance. Unsatisfactory and weak Ruffier test results are associated with elevated homocysteine levels in adolescents

Hormonal Imbalance as a Prognostic Factor of Physical Development of Children with Intellectual Disability.

The purpose was to study the indicators of physical development of primary-school-aged children with intellectual disability by observing the type of autonomic nervous regulation and their levels of catecholamines and serotonin. A total of 168 primary school age children were examined, of which 54 had intellectual disability. The autonomic nervous system was assessed using cardiointervalography; anthropometric parameters were applied in accordance with recommendations. The contents of serotonin and catecholamines in blood plasma and lymphocytes were assessed using enzyme immunoassay and luminescent histochemical methods. Delayed physical and mental development in children with intellectual disability were associated with low serotonin levels in this group of children. The optimal option for the physical development of children with intellectual disability is a sympathetic type of autonomic nervous regulation, while negative-type vagotonic nervous regulation was associated with the maximum delay in physical development. The hypersympathetic type of nervous regulation was accompanied by minimal changes in physical development, despite the hormonal imbalance in the ratio of catecholamines and serotonin. The level of the neurotransmitter serotonin is a prognostic marker of the physical development of children of primary school age. The total amount of catecholamines and serotonin in blood plasma has a direct relationship with the amount of these neurotransmitters in blood lymphocytes; the more hormones in plasma, the more of them in lymphocytes. Therefore, the determination of the contents of catecholamines and serotonin in lymphocytes can be used as a model for studying neurotransmitters in humans.

Observation on the Effect of Parental Participation in Nursing Under the IMCHB Model in Neonatal Hypoxic-Ischemic Encephalopathy

Objective: To investigate the clinical effects of parental participation in nursing under the Interaction Model of Client Health Behavior (IMCHB) model in neonatal hypoxic-ischemic encephalopathy (HIE). Methods: The First Affiliated Hospital of Gannan Medical University included 46 newborns with HIE admitted from October 2021 to October 2023 into the study population. They were divided into a control group and an observation group according to the random number table method, with the control group adopting routine nursing, and the observation group implementing parental participation in nursing under the IMCHB model. The indicators of physical, intellectual, and psychomotor development of the two groups were compared before and after nursing. Results: The physical, intellectual, and psychomotor development of the observation group was higher than that of the control group after 3 months of nursing, and the difference was statistically significant (P < 0.05). Conclusion: The implementation of the IMCHB model of parental participation in the clinical care of HIE neonates can further promote their physical, intellectual, and psychomotor development.

ВПЛИВ ІННОВАЦІЙНИХ ПІДХОДІВ НА ФІЗИЧНИЙ РОЗВИТОК ШКОЛЯРІВ З ВАДАМИ СЛУХУ В ПРОЦЕСІ АДАПТИВНОГО ФІЗИЧНОГОВИХОВАННЯ

Introduction. Correcting the physical development of students with hearing impairments requires an individual approach and the use of specialized methods and tools. Each student with hearing loss may have unique needs and capabilities. Therefore, it is important to create individualized physical education programs that take into account the specific limitations and capabilities of each student. It is important to develop and implement innovative approaches for children with hearing impairments that would have an impact on the physical development of schoolchildren along with the correctional and health-improving orientation of the entire process of adaptive physical education. The purpose of the study is to substantiate and implement an innovative methodology of adaptive physical culture for the correction of physical development of children with hearing impairments in the process of adaptive physical education. Research methods: theoretical analysis and generalisation of scientific literature data, sociological research methods, somatometric and physiometric research methods, methods of mathematical statistics. Results. The developed algorithm consisted of comparing two groups of 15-year- old schoolchildren with hearing impairment (boys (n=14), girls (n=12)) (control and experimental groups). Difference of content of classes in two groups of pupils was in means and methodical approaches to solution of correctional tasks in the process of physical education. In the first group, all training sessions were conducted in accordance with the physical education programme. In the second group, the methodology of correction of physical development included the following forms of training: exercises of different structure and focus to improve physical development indicators; increasing the level of functional capabilities of the cardiovascular and respiratory systems; balancing the psycho-emotional state (correctional games, tourist training skills, various types of health and recreational physical activity, improving the development of fine motor skills, exercises aimed at correcting and lagging behind in physical development), as well as an innovative program developed taking into account the needs and capabilities of children with hearing impairments. The innovative programme contained interactive exercises, included video tutorials with subtitles, games and tasks that can stimulate physical development, coordination and joint interaction.Conclusions. As a result, the implementation of the proposed methodology is confirmed by positive changes in the level of physical activity, improvement of general health and correction of physical development in the process of adaptive physical education of schoolchildren with hearing impairments.

Дослідження фізичного стану учнів 10-х класів ліцею спортивного профілю

Topicality. The educational and training process of specialized sports education institutions requires a systematic analysis of the physical development and the physical condition of young athletes. The Aim of the Study is to determine the level of the physical condition of 10th-grade students of the specialized sports profile lyceum based on anthropometric and medical-biological indicators and to investigate its dynamics over three years. Research Methods and Organization. The research was conducted during 2020–2022 on the basis of the Kharkiv Professional College of Sports. The anthropometric and medical-biological indicators of 10th-grade pupils of the lyceum over three years have been studied. The number of respondents was 210, and the average age of the representatives was 15,46 years. Anthropometric (measurement of anthropometric indicators) and medical-biological (spirometry, rhythm vasometry, electromanometry) research methods were applied. The level of physical condition was assessed according to the Pirogova index. One-dimensional statistical analysis according to the Student’s t-test was chosen to prove the regularities discovered in the process of research and hypothesis testing. Research Results. The study showed that the average values of the physical development indicators of the 10th-grade pupils of the lyceum of 2020–2022 years have no statistically significant differences and correspond to the rating of “average” for their age category. The average value of the physical condition index of the 10th graders of the lyceum ranges from 0,676 to 0,825 conditional units, which corresponds to the rating “above average”. However, during the three years of the study, the number of students with a “high” rating gradually decreases and the number of representatives with an assessment of the level of physical condition “above average” increases. Conclusion. Regular purposeful sports engagements and an increased level of physical activity allow ensuring a better physical condition level with average indicators of physical development. At the same time, the percentage ratio of physical condition assessments of 10th-grade lyceum pupils over three years shows a gradual deterioration of the indicator.

Dynamic changes in physical development indicators of high school-age children in the Samara region over a decade

Dynamic changes in physical development indicators of high school-age children in the Samara region over a decade

Interplay of the indicators of physical development and psychological status in the young adult medical students

Interplay of the indicators of physical development and psychological status in the young adult medical students

Pre-school children single inhalation anesthetic exposure and neuro-psychological development: a prospective study and Mendelian randomization analysis.

For children who are unable to cooperate due to severe dental anxiety (DA), dental treatment of childhood caries under Dental General Anesthesia (DGA) is a safe and high-quality treatment method. This study aims to evaluate the impact on neurocognitive functions and the growth and development of children 2 years after dental procedure based on previous research, and further establish a causal relationship between general anesthesia (GA) and changes in children's neurocognitive functions by incorporating Mendelian Randomization (MR) analysis. Data were collected and analyzed from 340 cases of S-ECC procedures of preschool children conducted in 2019. This involved comparing the neurocognitive outcomes 2 years post-operation of preschool children receiving dental procedures under general anesthesia or local anesthesia. Physical development indicators such as height, weight, and body mass index (BMI) of children were also compared at baseline, half a year post-operation, and 2 years post-operation. We performed a Mendelian randomization analysis on the causal relationship between children's cognitive development and general anesthesia, drawing on a large-scale meta-analysis of GWAS for anesthesia, including multiple general anesthesia datasets. Outcome data were obtained for 111 children in the general anesthesia group and 121 children in the local anesthesia group. The mean FSIQ score for the general anesthesia group was 106.77 (SD 6.96), while the mean score for the local anesthesia group was 106.36 (SD 5.88). FSIQ scores were equivalent between the two groups. The incidence of malnutrition in children in the general anesthesia group was 27.93% (p < 0.001) before surgery and decreased to 15.32% (p > 0.05) after 2 years, which was not different from the general population. The IVW method suggested that the causal estimate (p = 0.99 > 0.05, OR = 1.04, 95% CI = 5.98 × 10-4-1.82 × 103) was not statistically significant for disease prevalence. This indicates no genetic cause-and-effect relationship between anesthesia and childhood intelligence. There were no adverse outcomes in neurocognitive development in 2 years after severe early childhood caries (S-ECC) procedure under total sevoflurane-inhalation in preschool children. The malnutrition condition in children can be improved after S-ECC procedure under general anesthesia. Limited MR evidence does not support a correlation between genetic susceptibility to anesthesia and an increased risk for intelligence in children.

Фізична культура та спорт як фактор формування здорового способу життя населення

The purpose of this work. To conduct research and analysis of indicators of physical development and physical fitness of two groups of higher education students, as well as the functional state of their cardiovascular, muscular, and respiratory systems, in order to substantiate the importance and necessity of systematic physical education and sports. Materials and methods of research. In accordance with the purpose of the study, the following methods were used: theoretical (analysis and generalization of scientific literature), empirical (survey), testing to determine the physical fitness of students, physiometric and instrumental methods of studying the functional state of students' body systems. Results. Research and analysis of indicators of physical development, physical fitness, and functional state of body systems (cardiovascular, muscular, and respiratory) of higher education students at Cherkasy State Technological University were conducted. The analysis of the research results showed the importance of the role and place of physical culture and sports in preventive medicine and public health. Conclusions. The analyzed indicators of physical development, physical fitness of the studied groups of students, and the functional state of their cardiovascular, muscular, and respiratory systems showed how much physical education and sports allow young people to improve their physical fitness, maintain their health at an appropriate level to overcome life's difficulties, realize their abilities, and be useful to society. The results of our research to some extent coincide with the results of the research of many authors among different age categories of the population.

Самооценка физического здоровья студентов в процессе обучения в университете

Health and physical condition determine the success of students’ social self-development and professional selfrealization. The purpose of the study was to assess the health according to the physical development characteristics and functional condition of the first-year male students of Volgograd State University (n = 79). The results of measurements of students conducted under the guidance of a teacher and recorded in workbooks on physical education were analyzed. The data obtained were processed using mathematical statistics methods. Physical health indicators were test results that determine physical development and functional capabilities of students. High variability of indices evaluating physical development is shown, which indicates significant differences in the physical condition of first-year students. Participation of students in the self-assessment of indicators of physical development and functional fitness caused a critical attitude to their health, which was reflected in the formation of a conscious need for physical education. At the same time, some students understand that low indicators are the result of insufficient physical activity of students. It is indicated that in this situation, the main role in reducing the factors of physical inactivity is assigned to compulsory physical education classes provided by the state program, which are more likely to be tasked with the increase of physical activity of students.

Evaluation of the results of the study of individual indicators of physical development, special physical fitness and sports nutrition "Power Pro" of graduates of higher education with specific training conditions, engaged in mixed martial arts

Evaluation of the results of the study of individual indicators of physical development, special physical fitness and sports nutrition "Power Pro" of graduates of higher education with specific training conditions, engaged in mixed martial arts and law enforcement officers In order to achieve and maintain a high level of functional and physical fitness, high sports results, and maintaining the health of those who practice, a number of pedagogical, methodical, psychological, and medical-biological aspects are necessary. Therefore, the introduction of specialized sports nutrition is expedient. With the rational development of nutrition schemes, it is possible to increase the performance of athletes, improve all necessary indicators and planned results. The purpose of the article is to develop a program and recommendations for optimizing sports nutrition "Power Pro" and research the impact of specialized nutrition on individual anthropometric, indicators of general and special physical fitness of graduates of higher education with specific training conditions, engaged in mixed martial arts and law enforcement officers. The experiment involved young men (average age 19.10±0.74), high school graduates with specific training conditions, engaged in mixed martial arts and law enforcement officers (Dnipropetrovsk State University of Internal Affairs), who were divided into 2 groups – control (n= 15) and experimental (n=15). The purpose of using specialized sports nutrition was as follows: 1. Increasing both general and special fitness (training and competition). 2. Preventive action of possible injuries and disruption of adaptation. 3. Timely and correct recovery of the body of those who are engaged, after a state of overstrain. 4. Providing the body of those who are struggling with food substances, taking into account individual energy consumption. To test the developed program for the introduction of specialized sports nutrition, before and after the experiment, the following parameters were studied: height, weight, dynamometers, VL, impact force. We have developed and implemented schemes for the ratio and combination of food substances: whey protein, BCAA (branched chain amino acids), creatine, taurine, a complex of vitamins and minerals. When developing the program of specialized sports nutrition "Power Pro" for the experimental group, the main factors such as age characteristics and body weight, gender of the test subjects, as well as individual characteristics of their physical development, specifics of the sport were directly analyzed. The obtained results of the study showed a statistically significant improvement of individual anthropometric and indicators of special physical fitness in the experimental group (p&lt;0.05). This makes it possible to draw conclusions about the positive dynamics of the implemented program of specialized sports nutrition on the monitored indicators, which are basic for athletes specializing in mixed martial arts.

Interaction of integral parameters of physical state and biological age of students aged 17-19 years old in the process of adaptation to standard and experimental physical education programs

Background and Study Aim. The process of adaptation to physical education programs is a critical factor influencing the health and physical development of students. Understanding how these programs affect both the physical state and biological age of students can significantly improve their effectiveness. The aim of the study is to investigate the interaction between integral parameters of physical state (PS) and biological age (BA) of students aged 17-19 years old in the process of adaptation to standard and experimental physical education (PE) programs. Material and Methods. The study involved 140 first-year students of the National University of Telecommunications - 80 males and 60 females. In the course of the research, the indices of functional state, physical fitness (PF) and physical development (PD), biological age (BA) were recorded in young men and women of the control (CG) and experimental (EG) groups. To process the experimental material, methods of dispersion and canonical analysis were used and multiple correlation and determination coefficients were calculated. Results. It was revealed that the impact of PS integral parameters on students' BA is stronger than the inverse influence of BA on PS parameters. The degree of BA reduction under the influence of the studied factors is most pronounced in the EG of girls and boys. The variability of the group of PD and PF indices is accompanied by the variability of most of the BA parameters’ dispersion in all studied groups of students. The factor of gender has the greatest impact on the BA of students. Girls have lower initial values of BA and it’s a more pronounced decrease by the end of the experiment. The effectiveness of the impact of an aerobically oriented experimental program on the improvement of students’ PS and reduction of BA was confirmed. Under the influence of the experimental program, the BA of EG girls decreases to a greater extent in comparison with EG boys and students of both control groups. Changes and differences in BA of boys and girls of EG and CG are due to the combined impact of the factor of PE software and that of adaptation changes of students' PS in the annual process of PE. In the group of boys and girls more pronounced influence on BA in the course of the experiment was produced by the factor of software and adaptation changes, respectively. Conclusions. The gender factor has the strongest impact on students' BA - girls have lower initial values of BA and it’s a more pronounced decrease by the end of the experiment in comparison with boys. Adaptation changes of PS in the process of software implementation are accompanied by a decrease in BA in the experimental groups. One of the criteria and confirmations of the effectiveness of the developed PE program is the degree of mutual influence of PS integral parameters, which is most pronounced in the reduction of BA in the experimental groups of girls and boys.

Effects of Helicobacter pylori Infection Before and After Eradication Treatment on Physical Development and Nutritional Indicators of Children

Background: Helicobacter pylori (Hp) infection causes digestive disorders in children. Objectives: To investigate whether Hp infection affects the physical development and nutritional indicators of children. Methods: This retrospective study included 100 healthy children and 112 children with Hp infection who received eradication treatment. A retrospective statistical analysis was conducted on the height, weight, hemoglobin (Hb), serum ferritin (SF), serum iron (SI), albumin (ALB), and 25-(OH)D3 levels of all selected children. Results: Of the 112 children with Hp infection, 23 (20.5%) showed a positive 13C-urea breath test after a 1-year follow-up, and they were classified into the recurrence group. Following a 1-year follow-up, 89 (79.5%) children demonstrated negative results in the 13C-urea breath test and were selected for the non-recurrence group. Analysis of physical development and nutritional indices revealed lower Hb, SI, SF, and 25-(OH)D3 levels in the study group than in the control group before eradication treatment (P &lt; 0.05). However, no significant difference was observed between the control and study groups regarding body height, body weight, and ALB levels (P &gt; 0.05). Following 1 year of eradication treatment, Hb, SI, SF, 25-(OH)D3, and ALB levels showed no significant difference between the study and control groups (P &gt; 0.05). However, a relevant contrast was noted in 25-(OH)D3 levels between the non-recurrence and recurrence groups after 1 year of eradication treatment (P &lt; 0.05), with the former group having lower levels than the latter. Conclusions: Helicobacter pylori infection may impact Hb, SI, SF, and 25-(OH)D3 levels in children. Decreased 25-(OH)D3 may be a hazard for the recurrence of Hp infection.

DYNAMICS OF ANTHROPOMETRIC INDICATORS OF THE PHYSICAL DEVELOPMENT OF URBAN CHILDREN AND ADOLESCENTS FROM 1925 TO 2022 IN THE REPUBLIC OF BELARUS

Introduction. Secular changes in the somatometric parameters of children and adolescents of both sexes are observed in most countries of the world. The data in the literary sources are contradictory and indicate two opposite directions of the processes of changes in time the parameters of physical development - acceleration and deceleration, which points out to the need for their constant monitoring. Materials and methods. A comparative analysis of the main somatometric indicators of physical development (length and body weight) was carried out in children and adolescents of both sexes in the city of Gomel aged 8 to 16 years, obtained in 1925 (first group), 1973 (second group), 2010-2012 (third group), 2021-2022 (fourth group). These populations were homogeneous in place of residence, ethnicity, close in time of inspection and representative in number. The number of boys and girls in each age group was 100 or more people. Results. It was found that children and adolescents of both sexes of the Republic of Belarus examined in 2010-2012 and 2021-2022 had higher values of somatometric indicators (body length and weight) compared to their peers examined in 1925 and 1973 (p&lt;0,05-0,001). At the same time, there were practically no statistically significant differences between the anthropometric indicators of schoolchildren of two gender groups surveyed in 2010-2012 and in 2021-2022. Conclusion. A comparative analysis of the anthropometric indicators of children and adolescents of both sexes aged 8-16 years from 1925 to 2022 indicates that the process of acceleration among urban schoolchildren in Belarus observed in the period from 1925 to 2012 stopped, which is indicated by the absence of statistically significant differences between the anthropometric indicators of schoolchildren surveyed in 2010-2012 and in 2021-2022.