Synchronization Index Research Articles

Effect of Prenatal Yoga on Heart Rate Variability and Cardio-Respiratory Synchronization: A Prospective Cohort Study.

The objective was to assess the effects of prenatal yoga on heart rate variability (HRV) and cardio-respiratory synchronization, used as proxies of autonomic nervous system activity. Sixty-nine healthy pregnant women were included; 33 in a yoga group attending at least one 90-min yoga class weekly throughout pregnancy, and 36 controls not involved in formal pregnancy exercise programs. Measurements of the time domain (SDNN, standard deviation of regular R-R intervals, and RMSSD, square root of mean squared differences of successive R-R intervals) and frequency domain (ln(LF/HF), natural logarithm of low-frequency to high-frequency power) HRV indices, as well as cardio-respiratory synchronization indexes were performed once per trimester before and after yoga or 30-min moderate-intensity walk. A statistical comparison was performed using a three-way analysis of the variance (p < 0.05 significant). Both the time domain and frequency domain HRV indices showed significant shifts towards parasympathetic dominance following yoga when compared to the controls throughout pregnancy (p = 0.002 for SDNN, p < 0.001 for RMSSD, and p = 0.006 for ln(LF/HF), respectively). There was a statistically non-significant trend towards higher synchronization between respiratory frequency and heart rate following yoga vs. controls (p = 0.057). Regular prenatal yoga was associated with enhanced parasympathetic activation persisting throughout pregnancy.

Electrophysiological and functional signs of Guillain–Barré syndrome predicted by a multiscale neuromuscular computational model

Objective. The diagnosis of nerve disorders in humans has relied heavily on the measurement of electrical signals from nerves or muscles in response to electrical stimuli applied at appropriate locations on the body surface. The present study investigated the demyelinating subtype of Guillain–Barré syndrome using multiscale computational model simulations to verify how demyelination of peripheral axons may affect plantar flexion torque as well as the ongoing electromyogram (EMG) during voluntary isometric or isotonic contractions. Approach. Changes in axonal conduction velocities, mimicking those found in patients with the disease at different stages, were imposed on a multiscale computational neuromusculoskeletal model to simulate subjects performing unipodal plantar flexion force and position tasks. Main results. The simulated results indicated changes in the torque signal during the early phase of the disease while performing isotonic tasks, as well as in torque variability after partial conduction block while performing both isometric and isotonic tasks. Our results also indicated changes in the root mean square values and in the power spectrum of the soleus EMG signal as well as changes in the synchronization index computed from the firing times of the active motor units. All these quantitative changes in functional indicators suggest that the adoption of such additional measurements, such as torques and ongoing EMG, could be used with advantage in the diagnosis and be relevant in providing extra information for the neurologist about the level of the disease. Significance. Our findings enrich the knowledge of the possible ways demyelination affects force generation and position control during plantarflexion. Moreover, this work extends computational neuroscience to computational neurology and shows the potential of biologically compatible neuromuscular computational models in providing relevant quantitative signs that may be useful for diagnosis in the clinic, complementing the tools traditionally used in neurological electrodiagnosis.

Variation of Fertility and Phenological Synchronization in Cunninghamia lanceolata Seed Orchard: Implications for Seed Production

Reproductive synchronicity between parents influences the seed production and quality in seed orchards. Our objective was to determine clonal variation in fertility and phenological synchronization, as well as their effect on seed production, in a Chinese fir (Cunninghamia lanceolata) open-pollinated seed orchard. Significant variation of female fertility and male phenological synchronization occurred in the clones. The flowering of the male was 2 days earlier than the female. The gamete contribution of female and male were unbalanced between clones (the phenological synchronization indexes (POij) were 0.000–0.585 (as female) vs. 0.000–0.385 (as male)). In general, the average POij value of as a male was lower than as a female, but the number of male flowers were significantly higher than female, indicating that the management of female flowers should be enhanced. The average POij of self-pollination was 0.298, higher than cross-pollination (0.236), indicating that there was a larger probability to selfing in the orchard. The middle phenological type possessed higher phenological synchronization indexes than early and late phenological type. Genetic control was stronger for number of female flowers (H2 = 0.277) than for male and female initial stages and flower duration (H2 = 0.193–0.239). We found a positive correlation between POij and TSW (r = 0.756), SOsc (r = 0.612), and Cp (r = 0.337), suggesting the phenological synchronization determined the seed quality and yield. Comprehensively, this study provided fertility and phenology information for management of a Chinese fir seed orchard, as well as a reference for the establishment of advanced seed orchards of conifer trees.

Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults.

Sleep deprivation is associated with dysregulation of the autonomic nervous system, adverse cardiovascular events, cognitive and complex motor performance impairment. Less is known about the effects of acute total sleep deprivation (ATSD) on physiological coupling. We aimed to determine the effects of 24-h ATSD on the physiological coupling between complex subsystems by evaluating the cardiorespiratory, cardiovascular and cortico-cardiac interactions. This study enrolled 38 young healthy participants aged 23.2 ± 2.4 years. Multiple synchronous physiological signals including electrocardiography, photoplethysmography, bio-electrical impedance, electroencephalography, and continuous hemodynamic data, were performed over a baseline night after regular sleep and after a night with 24-h ATSD in the supine position. The magnitude squared coherence, phase synchronization index, and heartbeat evoked potential amplitudes, were obtained from 10-min synchronous physiological recordings to estimate the coupling strength between two time series. Parameters of hemodynamic characteristics and heart rate variability were also calculated to quantify autonomic regulation. Results indicated that the magnitude squared coherence (0.38 ± 0.17 vs. 0.29 ± 0.12, p = 0.015) between respiration and heart rate variability along with the magnitude squared coherence (0.36 ± 0.18 vs. 0.27 ± 0.13, p = 0.012) between respiration and pulse transit time were significantly decreased after 24-h ATSD. There were no significant differences (all p > 0.05) in phase synchronization indices, heartbeat evoked potential amplitudes as well as other analyzed measurements between baseline and 24-h ATSD states. We conclude that exposure to 24-h ATSD appears to weaken the cardiorespiratory and respiratory-cardiovascular coupling strength of young healthy adults. These findings suggest that physiological coupling analysis may serve as a complementary approach for characterizing and understanding the complex effects of sleep deprivation.

A comparison of muscle activation and concomitant intermuscular coupling of antagonist muscles among bench presses with different instability degrees in untrained men.

The aim of this study was to analyze and compare the muscle activation and concomitant intermuscular coupling of antagonist muscles among bench presses with different instability degrees. Twenty-nine untrained male college students performed bench press exercises at an intensity of 60% 1 RM on three conditions: small unstable bench press with Smith machine (SBP), medium unstable bench press of free weight (FWBP), and large unstable bench press with increased instability by suspending the load with elastic bands (IIBP). One-way repeated measures analysis of variance was used to compare integrated EMG activity values of the biceps brachii (BB), posterior deltoid (PD), long head of the triceps brachii (TB), anterior deltoid (AD), upper portion of the pectoralis major (PM) muscles, and phase synchronization index (PSI) of BB-TB and PD-AD antagonist muscle pairs. A higher integrated EMG of BB muscle was found during bench press with a more unstable condition. IIBP showed a higher integrated EMG of prime movers (TB, AD, and PM) and stabilizing of BB than SBP and FWBP. PSI between muscle pairs of BB-TB in the gamma frequency band was higher in SBP than the other bench presses with unstable conditions, which may be related to the optimal “internal model” for antagonist muscles during bench press exercise. Therefore, IIBP training may be an effective accessory exercise to maintain a higher level of muscle activation across primary and stabilizing muscles with a lighter load for untrained men, while SBP may be a suitable bench press exercise for untrained participants who have not developed the neuromuscular adaptations necessary for correct stabilization of the elbow joint.

Prediction of balance function for stroke based on EEG and fNIRS features during ankle dorsiflexion.

Balance rehabilitation is exceedingly crucial during stroke rehabilitation and is highly related to the stroke patients’ secondary injuries (caused by falling). Stroke patients focus on walking ability rehabilitation during the early stage. Ankle dorsiflexion can activate the brain areas of stroke patients, similar to walking. The combination of electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) was a new method, providing more beneficial information. We extracted the event-related desynchronization (ERD), oxygenated hemoglobin (HBO), and Phase Synchronization Index (PSI) features during ankle dorsiflexion from EEG and fNIRS. Moreover, we established a linear regression model to predict Berg Balance Scale (BBS) values and used an eightfold cross validation to test the model. The results showed that ERD, HBO, PSI, and age were critical biomarkers in predicting BBS. ERD and HBO during ankle dorsiflexion and age were promising biomarkers for stroke motor recovery.

Mixing Hydrogel Granules into Peat Substrate Improves Germination and Enhances Growth and Physiological Performance of Tomato Seedlings

Abstract The effects of hydrogel granules mixed with peat substrate on germination, morphological and physiological parameters of plugged seedlings were tested in tomato seedlings, at two different irrigation regimes. Due to hydrogel presence, the germination speed was increased, whereas mean germination time was significantly reduced. Slight improvement was recorded regarding final germination, but no effect was found regarding the synchronisation index and seedling vigour index. Due to addition of hydrogel granules a significant increase occurred in dry matter of shoots and plants. No effect was found regarding dry matter of roots, but the presence of hydrogel granules significantly reduced the length of tap root. Interestingly, stomata conductance and chlorophyll index were higher than in control plants. No statistically significant interaction was found between hydrogel variants and irrigation frequency, i.e., the effect of different levels of hydrogel variants did not depend on irrigation frequency. Therefore, we recommend mixing hydrogel capsules into the substrate of plug seedlings to improve the morphological and physiological parameters of seedlings and reduce water and fertiliser leaching into the environment.

Are Psychophysiological Wearables Suitable for Comparing Pedagogical Teaching Approaches?

This study describes how wearable devices can be used in elementary schools to compare some aspects of different teaching approaches. Upper arm wearables were used as an objective tool to compare three approaches when teaching science: (i) classical frontal teaching, (ii) embodied (kinesthetic) teaching, and (iii) a distance teaching approach. Using the wearables, the approaches were compared in terms of their impact on students’ psychological arousal and perceived well-being. In addition, short-term and long-term knowledge gain and physiological synchronization between teacher and students during the lecture were assessed. A synchronization index was defined to estimate the degree of physiological synchronization. During distance teaching, by means of measurements with wearables, students were significantly less physically active and significantly less psychologically aroused. Embodied teaching allowed significantly higher physical activation than during the other two approaches. The synchronization index for all three teaching approaches was positive with the highest values for distance and frontal teaching. Moreover, knowledge gain immediately after the embodied lessons was higher than after frontal lessons. No significant differences in the long-term knowledge retention between the three different teaching methods were found. This pilot study proved that wearables are a useful tool in research in the field of education and have the potential to contribute to a deeper understanding of the mechanisms involved in learning, even in complex environments such as an elementary school classroom.

Generation and Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus: A Core-Shell Model.

We focus our research on how the core-shell organization controls behavior of the suprachiasmatic nucleus (SCN), how the core and shell are synchronized to the environment, what impact they have on the behavior of the SCN under different lighting conditions, and what mechanisms disrupt synchronization. To this end, we use a reduced Kuramoto model, with parameters inferred from experimental observations and calibrated for mice, and perform a detailed comparison between the model and experimental data under light-dark (LD), dark-dark (DD), and light-light (LL) conditions. The operating limits of free-running and entrained SCN activity under symmetric LD cycles are analyzed, with particular focus on the phenomena of anticipation and dissociation. Results reveal that the core-shell organization of the SCN enables anticipation of future events over circadian cycles. The model predicts the emergence of a second (dissociated) rhythm for large and small LD periods. Our results are in good qualitative and quantitative agreement with experimental observations of circadian dissociation. We further describe SCN activity under LL conditions and show that our model satisfies Aschoff’s first rule, according to which the endogenous free-running circadian period observed under complete darkness will shorten in diurnal animals and lengthen in nocturnal animals under constant light. Our results strongly suggest that the Kuramoto model captures essential features of synchronization and entrainment in the SCN. Moreover, our approach is easily extendible to an arbitrary number of groups, with dynamics described by explicit equations for the group phase and synchronization index. Viewed together, the reduced Kuramoto model presents itself as a useful tool for exploring open problems in the study of circadian rhythms, one that can account for evolving views of the circadian system’s organization, including peripheral clocks and inter-hemispheric interaction, and can be translated to other nocturnal and diurnal animals, including humans.

The climate cost of saving water by different plastic mulching patterns

Global water shortage and climate change are two of the most significant challenges for our planet, and how to coordinate their relationship is a problem unsolved. In this study, we proposed the synchronization index of water-saving and CO2 mitigation to evaluate the climate cost of saving water by different plastic mulching patterns and explore way to improve the synchronization. The water-saving performance, carbon footprint, and the synchronization index were analyzed for three typical plastic mulching patterns, namely conventional partial plastic mulching, full plastic mulching, and “one film for two years” mulching. The results indicated that all three types of plastic mulching systems were effective in reducing the water footprint of crop production, with full plastic mulching showing the best performance in terms of improving crop yields and water savings. The application of plastic mulching mainly influences the carbon footprint through increasing indirect greenhouse gas emission, accelerating soil organic carbon decline and increasing N2O emission. Area-scale carbon footprint showed a significant positive relationship with the input amounts of plastic film, and the sort order of yield-scale carbon footprint was partial plastic mulching > full plastic mulching > “one film for two years” mulching. Calculated synchronization index was -0.35 kg CO2-eq m−3, -0.10 kg CO2-eq m−3, and 0.50 kg CO2-eq m−3 for partial plastic mulching, full plastic mulching, and “one film for two years” mulching, respectively. Full plastic mulching and partial plastic mulching resulted in an additional 0.35 and 0.10 kg of CO2-eq for saving one cubic meter of water, and only “one film for two years” mulching resulted in simultaneous water savings and greenhouse gas mitigation. This study suggests that water savings achieved using conventional partial plastic mulching have costs in terms of climate change. Faced with the dual pressure of global water shortages and climate change, controlling input amounts of plastic film and prolonging the lifetime of the film are simple and effective way to coordinate water savings and greenhouse gas mitigation. Moreover, the results of this study suggested that water savings and GHG emission mitigation cannot necessarily be achieved simultaneously and that searching for both water-saving performance and its synchronization with GHG mitigation should become a new paradigm for the development of water-saving technologies in the future.

A New Novel Synchronization Index of Brain Networks in Hyperbolic EEG Dynamics

The functional connectivity of brain connectivity changes its pattern over time i.e. dynamics, even in the resting state with an infinite number of degrees of freedom with local couplings. Recently, quantifying the level of synchrony has received considerable attention. We hypothesized that time-varying instantaneous phase synchronization over local couplings are defined in hyperbolic space and different brain regions can identify failures, flexibility, and stability in network dynamics. Our goal is to understand the phase synchronization changes of the beta-gamma band, and in addition, to investigate Shannon entropy based on phase synchronization stability. Whole EEG dynamics from local phase synchronizations was used to detect treatment resistance from both hemispheres in OCD patients. Temporal filtering and Hilbert transforms were performed to infer beta-gamma band phase difference activity from the EEG brain dynamics. Then, the response beta-gamma band phase stability was quantified using a new phase synchronization index (PSI). Results indicated significantly changed phase synchronization of the response and non-response to treatment, patients in OCD patients in F7 electrode. Greater phase fluctuations of beta-gamma synchronizations in treatment resistance OCD is claiming phase deficiencies within neural populations. This study first provides experimental and theoretical support for characterizing cycle structure depends on the non-Euclidian dynamics of neural phase synchrony caused by disturbances of underlying neurotransmitter systems, as reflected in different normal and disease states.

Heart-brain synchronization breakdown in Parkinson’s disease

Heart rate variability (HRV) abnormalities are potential early biomarkers in Parkinson’s disease (PD) but their relationship with central autonomic network (CAN) activity is not fully understood. We analyzed the synchronization between HRV and brain activity in 31 PD patients and 21 age-matched healthy controls using blood-oxygen-level-dependent (BOLD) signals from resting-state functional brain MRI and HRV metrics from finger plethysmography recorded for 7.40 min. We additionally quantified autonomic symptoms (SCOPA-AUT) and objective autonomic cardiovascular parameters (blood pressure and heart rate) during deep breathing, Valsalva, and head-up tilt, which were used to classify the clinical severity of dysautonomia. We evaluated HRV and BOLD signals synchronization (HRV-BOLD-sync) with Pearson lagged cross-correlations and Fisher’s statistics for combining window-length-dependent HRV-BOLD-Sync Maps and assessed their association with clinical dysautonomia. HRV-BOLD-sync was lower significantly in PD than in controls in various brain regions within CAN or in networks involved in autonomic modulation. Moreover, heart-brain synchronization index (HBSI), which quantifies heart-brain synchronization at a single-subject level, showed an inverse exposure–response relationship with dysautonomia severity, finding the lowest HBSI in patients with severe dysautonomia, followed by moderate, mild, and, lastly, controls. Importantly, HBSI was associated in PD, but not in controls, with Valsalva pressure recovery time (sympathetic), deep breathing E/I ratio (cardiovagal), and SCOPA-AUT. Our findings support the existence of heart-brain de-synchronization in PD with an impact on clinically relevant autonomic outcomes.

Macronutrient Digestibilities and Enzyme Activities in Rumen Fluid Supplemented by Protein-Energy Synchronized Index-Based Rations

The protein-energy synchronized (PES) index-based rations can optimize microbial protein synthesis (MPS) and affect enzyme activity and macronutrient digestibility of ration in rumen fluid. This study aimed to examine the in vitro effect of a ration based on PES index on macronutrient digestibility and enzyme activity in rumen fluid. The research was conducted experimentally, consisting of 4 treatment rations with different PES indexes (R1: 0.55; R2: 0.6; R3: 0.65; R4: 0.7). Each treatment was repeated 5 times, so there were 24 experimental units. The material used was the rumen fluid of the Jawa Randu Goat, which was taken at the Sokaraja Slaughterhouse shortly after the goat was slaughtered. Each ration consisted of napier grass, river tamarind, coconut meal, soybean dregs, rice bran, cassava waste, and mineral mix. The results showed that the PES index significantly affected (P&lt;0,01) the digestibility of protein (A), fiber (B), and fat (C), as well as the activity of protease (D) and cellulase (E) enzymes. Theorthogonal polynomial test showed that the PES index has a quadratic effect on all test parameters with the following equation: A (Y= -1229.5X2 + 1540.6X -457.57; R2= 0.75), B (Y = -800.95X2+ 955.86X -264.51; R² = 0.75), C (Y = 868.92X2-1038.2X + 325.1; R2= 0.81), D (Y = -41.4X2+ 51.697X -14.982; R² = 0.77), and E (Y = -4.8538X2+ 5.927X -1.6241; R² = 0.84). The protein-energy synchronized index-based rations increased the in vitro of macronutrient digestibility (protein, fiber, and fat) and enzyme activity on rumen fluid at a medium index level (0.6-0.63).

Changes in Postural Control Ability after Wearing Corrective Glasses for Distance in Older Adults and Their Causes.

Deterioration of postural control in older adults is unavoidable due to age-associated degeneration of the visual system. Our study objective was therefore to verify whether there is a positive effect on postural control ability after providing older adults, whose postural control function had deteriorated, with corrective glasses to correct refractive errors. Twenty-seven participants, 66 to 90 years of age, were included in this study. Stability index, synchronization index, and sway power index were measured by using the TETRAX balance system and comparatively analyzed before and after wearing the corrective glasses for distance. The stability index after wearing corrective glasses significantly decreased compared to before wearing them (p < 0.05). Four synchronization areas, among six, showed a significant increase in the synchronization index after wearing corrective glasses compared to before wearing them (p < 0.05). The sway power index significantly decreased in the mid–high and the high frequency after wearing the corrective glasses (p < 0.05). Optimal visual information can be obtained through the correction of residual refractive errors, eliciting a positive effect on the overall posture control by improving the sensory integration ability with the somatic nervous system responsible for posture control, maximizing the lower extremity motor function of the elderly.

Cognitive control, interference inhibition, and ordering of information during working memory in younger and older healthy adults.

Investigatingeffects of aging on neurophysiological mechanisms underlying working memory provides a better understanding of potential targets for brain intervention to prevent cognitive decline. Theta-gamma coupling (TGC) indexes the ability to order information processed during working memory tasks. Frontal theta event-related synchronization (ERS) and parietal alpha event-related desynchronization (ERD) index cognitive control and interference inhibition, respectively. Relative contributions of TGC, theta ERS, and alpha ERD in relation to stimulus presentation are not characterized. Further, differential effect of normal aging on pre- or post-stimulus processes is unknown. Electroencephalography was recorded in 66 younger and 41 older healthy participants while performing 3-back working memory task. We assessed relationships between 3-back task performance and each of post-stimulus TGC, pre-stimulus parietal alpha ERD, and pre-stimulus frontal theta ERS in each age group. While older adults performed worse on 3-back task than younger adults, TGC, alpha ERD, or theta ERS did not differ between the two groups. TGC was positively associated with 3-back performance in both age groups; pre-stimulus alpha ERD was associated with performance among younger adults; and pre-stimulus theta ERS was not associated with performance in either group. Our findings suggest that both pre-stimulus interference inhibition and post-stimulus ordering of information are important for working memory in younger adults. In contrast, performance in older adults appears to depend only on post-stimulus ordering of information. These specific contributions of neurophysiological resources may explain the poorer performance of older adults and suggest different targets to enhance working memory in age groups.

P416. Cerebral Blood Flow and Cardiovascular Risk Factor Effects on Resting Brain Regional Homogeneity

Regional homogeneity (ReHo) is a local synchronization index computed from brain resting state functional MRI timeseries and has been proposed as a measure of local functional connectivity. ReHo abnormalities are reported in a wide range of neurological and psychiatric disorders. However, ReHo measure is sensitive to local fluctuations in cerebral blood flow (CBF) that is in turn influenced by system-level cerebrovascular health. We hypothesize that ReHo signal may be influenced by CBF in a regionally specific way; and the latter is affected by the global cardiovascular factors.

Stock Market Synchronization: The Role of Geopolitical Risk

Given the importance of stock market synchronization for international portfolio diversification, we estimate the degrees of co-movements among US, Chinese and Russian markets. By applying the TVP-VAR approach, we measure total and bivariate synchronization indices utilizing daily data from 1998 to 2021. Our analysis demonstrates that the total connectedness index (TCI) is 26.15% among the three markets. We find that the US market is the highest volatility contributor, whereas the Russian market is the highest receiver. Since stock market synchronization is exposed to geopolitical risk, at the second stage, we apply the Quantile-on-Quantile framework to measure the response of total and bilateral connectedness indices to geopolitical risk (GPR). The findings affirm our proposition that GPR impedes TCI when it has a bullish state and a higher quantile of GPR. The response of bilateral connectedness is negative towards GPR concerning US–China and US–Russian pairs. However, the degree of connectedness between Russian and Chinese stock markets is less responsive to GPR.

Reaction mechanism of the gas-phase pyrolysis of N – Acetylthiourea and N, N’–diacetylthiourea: A theoretical study based in density functional theory

In the present study, we propose a reaction mechanism for the decomposition of N -Acetylthiourea and N, N '-Diacetylthiourea using density functional quantum chemical calculations. For both reactions the level of theory that gave us the better agreement between theory and experiment was MPW1PW91/6-311G (d, p). Thermodynamic and kinetic parameters were evaluated at 600 K and 1 atm. For N -Acetylthiourea decomposition reaction, the products are ketene and thiourea, while for are N, N '-Diacetylthiourea, the product are ketene and N–Acetylthiourea. Our calculations suggest that the mechanism proceeds stepwise, where the rate-determining step is promoted by an intramolecular nucleophilic attack of the sulfur atom to the carbonyl carbon in the acetyl group. The kinetics of these reactions is influenced by the electron-withdrawing effect of the acetyl group. Population analysis shows that the mechanism is predominantly synchronous as demonstrated by the high values ​​of the Wiberg synchronicity index. A non-covalent interactions study was also carried out in each stage of the reaction, as well as the analysis of the binding forces of the structures was followed by the independent gradient model (IGM) and its descriptor δg.

Localization and diagnosis of abnormal channels in children with ASD based on WMSSE and ASI

BackgroundThe purpose of this study is to explore the differences of resting EEG in children with autism spectrum disorders and then analyze the sensitive channels with significant differences, to provide support for the accurate differential diagnosis of autism spectrum disorder (ASD). New methodBased on the weighted multi-scale sample entropy (WMSSE) algorithm and amplitude synchronization index (ASI) algorithm of EEG, this paper comprehensively evaluates the brain state of ASD children from the two aspects of brain function complexity and brain function synchronization connectivity. Further, by combining the support vector machine (SVM) classification model to explore the location of abnormal channels of ASD children and realize the diagnosis of ASD children. ResultsThe WMSSE of the ASD group was lower than that of the healthy group. Furthermore, there was a significant difference in the F3/F4 channels and F7/F8 channels (P < 0.05), and the synchronization of the brain in the ASD group was also lower than that of the healthy group in Delta, Theta, Alpha, Beta band. Finally, combined with the WMSSE and ASI features of the F3/F4 channels (posterior frontal lobe) and F7/F8 channels (anterior temporal lobe), the classification accuracy and AUC value of ASD patients calculated by the SVM classification model were 82.7 ± 3.2%/ 0.795 (F3 / F4 channels), 89.8 ± 1.7%/ 0.812 (F7 / F8 channels). Comparison with existing methodsIt avoids the one-sided problem of single analysis complexity and synchronous connectivity, and provides a research basis for the comprehensive evaluation of ASD brain function. ConclusionWMSSE and ASI can be used as effective potential biomarkers for ASD diagnosis, and F7 and F8 channels can be preliminarily located as abnormal sensitive channels for ASD brain regulation. It also proves that the feature analysis of comprehensive complexity and synchronous connectivity is more conducive to the abnormal diagnosis of ASD patients.

Seed germination of Astronium urundeuva (M. Allemão) Engl. and Anadenanthera colubrina (Vell.) Brenan in different substrates

The present study evaluated the effect of different substrates on the germination and initial development of Astronium urundeuva and Anadenanthera colubrina. The substrates were: washed sand, vegetable soil, and vermiculite for A. urundeuva experiment; washed sand and vermiculite for A. colubrina experiment. The following variables were analyzed: percentage of emergence, emergence speed index, average emergence time, average emergence speed, synchronization index, first emergency count, and the relative frequency of emergence. For initial development, shoot and root length, number of leaves, and shoot, root and total dry mass were evaluated. The highest percentages of emergence for A. urundeuva (52%) and for A. colubrina (50.5%) were observed in vermiculite substrate. The use of vermiculite as substrate favored germination and initial development of A. urundeuva and A. colubrina.