Index Of Sexual Satisfaction Research Articles

Relationship between employment status and sexual functioning after traumatic brain injury

Objective: To determine if correlations exist between employment status and sexual functioning in persons with traumatic brain injury (TBI).Design: Descriptive cross-sectional.Setting: Community.Participants: One hundred and forty-six English-speaking, community dwelling adults, without other neurological or psychiatric disorder that could impact outcome and (1) enrolled in TBI Model Systems sexuality study database or (2) admitted to Rehabilitation Institute of Chicago with primary diagnosis of TBI between 2004–2006.Main outcome measures: Employment status, annual income, Derogatis Interview for Sexual Functioning Self Report (DISF-SR) sum and sub-scale scores, Global Sexual Satisfaction Index (GSSI).Results: No significant difference was found in GSSI scores between employed, unemployed or students/volunteers (p = 0.20); however, lower income marginally correlated with lower GSSI scores (p = 0.09). Marginally significant lower DISF-SR Sexual Cognition sub-group (p = 0.09) scores were found in unemployed vs. employed. Lower annual income also correlated with lower DISF-SR sum scores (p = 0.06), Sexual cognition/fantasy (p = 0.07), Orgasm/ejaculation (p = 0.003) and Sexual drive and relationship (p = 0.01) scores.Conclusions: Lower quality sexual functioning and satisfaction was present in persons with TBI and concomitant unemployment or lower annual income. Efforts are needed to increase awareness amongst the TBI population and rehabilitation professionals of the potential impact unemployment or financial stress has on sexual functioning and satisfaction.

Sexual Behavior and Sexual Satisfaction according to Gender in Korean Patients with Cancer.

This study was done to investigate sexual behavior and sexual satisfaction according to gender difference in Korean patients with cancer. In this study, a convenience sample of Korean patients with cancer who visited hospitals in J City was used. Data were collected between September and December 2012using structured questionnaires: Sexual frequency scale and General sexual satisfaction index (GSSI). Over half of the patients reported loss of sexual desire and changes in sexual behaviors. There was a significant decrease in sexual satisfaction among the male patients, compared to the female patients (t=2.34, p=.020). There were significant correlations between sexual satisfaction and sexual behaviors (male patients r=.45, p<.001; female patients r=.59, p<.001). The results of this study demonstrate the need to take gender into account in developing interventions for patients with cancer. These results will also contribute to the development of improved interventions for sexual health care.

Longitudinal trajectory of sexual functioning after hematopoietic cell transplantation: impact of chronic graft-versus-host disease and total body irradiation

AbstractThis prospective study described the trajectory of sexual well-being from before hematopoietic cell transplantation (HCT) to 3 years after in 131 allogeneic and 146 autologous HCT recipients using Derogatis Interview for Sexual Function and Derogatis Global Sexual Satisfaction Index. Sixty-one percent of men and 37% of women were sexually active pre-HCT; the prevalence declined to 51% (P = .01) in men and increased to 48% (P = .02) in women at 3 years post-HCT. After HCT, sexual satisfaction declined in both sexes (P < .001). All sexual function domains were worse in women compared with men (P ≤ .001). Orgasm (P = .002) and drive/relationship (P < .001) declined in men, but sexual cognition/fantasy (P = .01) and sexual behavior/experience (P = .01) improved in women. Older age negatively impacted sexual function post-HCT in both sexes (P < .01). Chronic graft-versus-host disease was associated with lower sexual cognition/fantasy (P = .003) and orgasm (P = .006) in men and sexual arousal (P = .05) and sexual satisfaction (P = .005) in women. All male sexual function domains declined after total body irradiation (P < .05). This study identifies vulnerable subpopulations that could benefit from interventional strategies to improve sexual well-being.

A Psychometric Comparison of Three Scales and a Single-Item Measure to Assess Sexual Satisfaction

This study was designed to systematically compare and contrast the psychometric properties of three scales developed to measure sexual satisfaction and a single-item measure of sexual satisfaction. The Index of Sexual Satisfaction (ISS), Global Measure of Sexual Satisfaction (GMSEX), and the New Sexual Satisfaction Scale–Short (NSSS-S) were compared to one another and to a single-item measure of sexual satisfaction. Conceptualization of the constructs, distribution of scores, internal consistency, convergent validity, test-retest reliability, and factor structure were compared between the measures. A total of 211 men and 214 women completed the scales and a measure of relationship satisfaction, with 33% (n = 139) of the sample reassessed two months later. All scales demonstrated appropriate distribution of scores and adequate internal consistency. The GMSEX, NSSS-S, and the single-item measure demonstrated convergent validity. Test-retest reliability was demonstrated by the ISS, GMSEX, and NSSS-S, but not the single-item measure. Taken together, the GMSEX received the strongest psychometric support in this sample for a unidimensional measure of sexual satisfaction and the NSSS-S received the strongest psychometric support in this sample for a bidimensional measure of sexual satisfaction.

AB1091 Evaluation of sexual satisfaction in fibromyalgic patients

BackgroundFM is a chronic disease affecting predominantly women and characterized by widespread pain, fatigue and several symptoms that may cause severe disability and impairment of quality of life including sexual...

Relación entre el grado de actividad física y la satisfacción sexual y corporal en estudiantes universitarios costarricenses

The purpose of the study was to describe the relationship between body image satisfaction (BS), sexual satisfaction (SS) and physical activity level (PAL) in a sample of male and female, single and heterosexual Costa Rican students. In the study participated 179 students (39 sedentary females, 40 sedentary males, 34 physically active females and 66 physically active males) with a mean age of 20.4 } 3 yrs. Participants completed the IPAQ-7, the Sexual Satisfaction Index (SSI) and the Spanish version of the Multidimensional Body Self Relations Questionnaire (MBSRQ). Two-way 2 x 2 independent groups (Gender x PAL) analysis of variance were computed. Results indicated no significant correlations between PAL, BS and the SS in college males and females.

Predictors of Sexual Functioning and Satisfaction 1 Year Following Traumatic Brain Injury

To investigate predictors of sexual functioning 1 year following traumatic brain injury (TBI). Prospective cohort study. Community. A total of 255 persons with TBI (187 males; 68 females) who had been treated at 1 of 6 TBI Model Systems inpatient rehabilitation units and were living in the community. Derogatis Interview for Sexual Functioning-Self-Report (DISF-SR); Global Satisfaction With Sexual Functioning (Global Sexual Satisfaction Index); Participation Assessment With Recombined Tools-Objective; Patient Health Questionnaire-9. Older age, female gender, and more severe injury were associated with greater sexual dysfunction 1 year following injury. As age increased from 24 to 49 years, the odds of sexual impairment increased more than 3-fold (95% confidence interval: 1.82-5.88). Females had a 2.5 increase in odds of sexual impairment compared with males (95% confidence interval: 1.23-5.26). Greater social participation was predictive of better sexual functioning. Dissatisfaction with sexual functioning was predicted by older age and depression. Older persons and females appear to be at greater risk for sexual dysfunction after TBI and may benefit from specialized assessment and treatment services. Relationships were identified between social participation and sexual function and between depression and sexual satisfaction that may serve as clinical indicators for further assessment and intervention. Further research is needed to elucidate these relationships and identify effective clinical approaches.

Changes in Sexual Functioning From 6 to 12 Months Following Traumatic Brain Injury

To investigate longitudinal changes in sexual functioning during the first year following moderate to severe traumatic brain injury (TBI). Prospective cohort study. Community. 182 persons (53 women and 129 men) with moderate to severe TBI who were admitted to 1 of 6 participating TBI Model System centers and followed in the community at 6 and 12 months after injury. Derogatis Interview for Sexual Functioning-Self-Report (DISF-SR); Global Sexual Satisfaction Index (GSSI). Mean T-scores on the DISF-SR Arousal subscale demonstrated marginal improvement over time, with a 2.59-point increase (P = .05) from 6 to 12 months after injury. There were no significant differences over this 6-month period on the remaining DISF-SR subscales, including sexual cognition/fantasy, sexual behavior/experience, and orgasm. There was no significant change in satisfaction with sexual functioning on the GSSI from 6 months (72% satisfied) to 12 months (71% satisfied). Sexual function and satisfaction appears to be stable in those with moderate to severe TBI from 6 to 12 months after injury, with the exception of minimal improvement in arousal. These findings, to our knowledge, reflect the first evidence regarding prospective changes in sexual functioning in this population. Future research can go far to assist clinicians in treatment planning and managing patient expectations of recovery of sexual functioning after TBI.

Sexual Functioning 1 Year After Traumatic Brain Injury: Findings From a Prospective Traumatic Brain Injury Model Systems Collaborative Study

Sander AM, Maestas KL, Pappadis MR, Sherer M, Hammond FM, Hanks R, and the NIDRR Traumatic Brain Injury Model Systems Module Project on Sexuality After TBI. Sexual functioning 1 year after traumatic brain injury: findings from a prospective Traumatic Brain Injury Model Systems collaborative study. ObjectiveTo investigate the incidence and types of sexual difficulties in men and women with traumatic brain injury (TBI) 1 year after injury, as well as their comfort level in discussing problems with health care professionals. DesignProspective cohort study. SettingCommunity. ParticipantsPersons with TBI (N=223; 165 men and 58 women) who had been treated at 1 of 6 participating TBI Model Systems inpatient rehabilitation units and were living in the community. InterventionsNone. Main Outcome MeasuresDerogatis Interview for Sexual Functioning-self-report (DISF-SR); Global Sexual Satisfaction Index (GSSI); structured interview regarding changes in sexual functioning; and comfort level discussing sexuality with health care professionals. ResultsWomen with TBI scored significantly below the normative sample for all subscales of the DISF-SR, including sexual cognition/fantasy, arousal, sexual behavior/experience, and orgasm. Men scored significantly below the normative sample on all scales except arousal. Women reported greater dysfunction than men for sexual cognition/fantasy and arousal. Twenty-nine percent of participants reported dissatisfaction with sexual functioning on the GSSI, with a greater percentage of men reporting dissatisfaction. Sixty-eight percent of participants indicated that they would spontaneously raise issues of sexual difficulties with health care professionals, while the remainder would either bring it up only if directly asked or would not discuss it at all. ConclusionsSexual difficulties were present in a substantial portion of community-dwelling people with TBI at 1 year after injury. Educational interventions to increase awareness among people with TBI and rehabilitation professionals are warranted, as well as interventions to improve sexual functioning.

Romantic Attachment Insecurity Predicts Sexual Dissatisfaction in Couples Seeking Marital Therapy

Researchers and practitioners have noted the importance of considering individual characteristics as well as couple dynamics when attempting to understand couples and sexual difficulties. Using a dyadic approach, this study examined the links between 2 forms of romantic attachment insecurity (anxiety and avoidance) and sexual dissatisfaction among members of couples seeking couple therapy. A large clinical sample of 242 French-speaking couples completed the Experiences in Close Relationships Scale and the Index of Sexual Satisfaction. Analyses based on the actor–partner interdependence model revealed that both attachment anxiety and avoidance predicted individuals’ own sexual dissatisfaction (actor effects). The authors also observed 2 partner effects: (a) anxiety in men predicted female partners’ sexual dissatisfaction and (b) avoidance in women predicted male partners’ sexual dissatisfaction. The results support attachment theory and have clinical implications for emotion-focused couple therapy and other approaches to couple therapy.

Validación del Massachusetts General Hospital-Sexual Functioning Questionnaire (MGH-SFQ) en población española

ObjectiveDue to the lack of psychometric studies using the Massachusetts General Hospital-Sexual Functioning Questionnaire (MGH-SFQ) in Spain, its Spanish validation is proposed in the present study, by analysing its reliability and validity. DesignCross-sectional descriptive study. SettingGeneral population. Conducted in 20 provinces. ParticipantsThe sample consisted of 3,050 participants (45.41% men and 54.59% women) and was selected using a quota convenience sampling procedure. They ranged in age from 18 to 83 years-old (M=41.51; SD=13.45). Main measurementsSpanish versions of the MGH-SFQ, Sexual Assertiveness Scale, Sexual Desire Inventory, and Index of Sexual Satisfaction. ResultsThe MGH-SFQ showed a single dimensional structure, which explained 71.35% of variance in men and 83.56% in women. Reliability values were .90 and .93, respectively. Convergent validity was adequate as their scores were positively correlated to initiation sexual assertiveness, dyadic sexual desire, and sexual satisfaction. The MGH-SFQ identified that females showed more sexual dysfunctions than males, and detected more sexual dysfunctions as age increases. ConclusionsThe Spanish validation of the MGH-SFQ is a reliable and valid self-reporting questionnaire to assess sexual dysfunctions in Spain. Its psychometric goodness of fit, together with its brevity and ease of use, make it a useful instrument to detect overall, as well as particular sexual dysfunctions.

Validação de uma versão portuguesa masculina do Índice de Satisfação Sexual

IntroductionSexual satisfaction is the psychological dimension most assessed in the area of sexual dysfunctions. ObjectiveThis study has aimed to validate a Portuguese male version of the Index of Sexual Satisfaction (ISS), a scale that assesses sexual satisfaction. Material and methodsA total of 305 men, subdivided into a community sample (n=249) and a clinical sample (n=56), participated in this study. They answered the Portuguese version of the questionnaire. ResultsThe main psychometric properties of the Portuguese version of the ISS were demonstrated. DiscussionThe original unidimensional structure of the ISS was replicated. Good values were also obtained in terms of internal consistency (Cronbach's alpha), temporal stability, convergent and divergent validity, and discriminant validity. ConclusionsThe use of the Portuguese male version of the ISS is justified since it has sound psychometric properties.

Randomized trial of leuprolide versus continuous oral contraceptives in the treatment of endometriosis-associated pelvic pain

To compare the efficacy of leuprolide and continuous oral contraceptives in the treatment of endometriosis-associated pain. Prospective, randomized, double-blind controlled trial. Academic medical centers in Rochester, New York, and Boston, Massachusetts. Forty-seven women with endometriosis-associated pelvic pain. Forty-eight weeks of either depot leuprolide, 11.25 mg IM every 12 weeks with hormonal add-back using norethindrone acetate 5 mg orally, daily; or a generic monophasic oral contraceptive (1 mg norethindrone + 35 mg ethinyl estradiol) given daily. Biberoglu and Behrman (B&B) pain scores, numerical rating scores (NRS), Beck Depression Inventory (BDI), and Index of Sexual Satisfaction (ISS). Based on enrollment of 47 women randomized to continuous oral contraceptives and to leuprolide, there were statistically significant declines in B&B, NRS, and BDI scores from baseline in both groups. There were no significant differences, however, in the extent of reduction in these measures between the groups. Leuprolide and continuous oral contraceptives appear to be equally effective in the treatment of endometriosis-associated pelvic pain.

Oral Desipramine and Topical Lidocaine for Vulvodynia

To estimate the efficacy of common treatments for vulvodynia: topical lidocaine monotherapy, oral desipramine monotherapy, and lidocaine-desipramine combined therapy. A 12-week randomized, double-blinded, placebo-controlled trial was conducted on 133 vulvodynia-afflicted women assigned to four treatment arms: placebo tablets-placebo cream, desipramine tablets-placebo cream, placebo tablets-lidocaine cream, and desipramine tablets-lidocaine cream. The tampon test was selected as primary end point using a modified intention-to-treat analysis. Twelve secondary end points were also examined. At completion of the 12-week randomized phase, women were examined "open label" through 52 weeks postrandomization. All treatment arms reported substantial tampon-test pain reduction: 33% reduction placebo cream-placebo tablet, 20% reduction lidocaine cream-placebo tablet, 24% reduction placebo cream-desipramine tablet, and 36% reduction lidocaine cream-desipramine tablet. Compared with placebo, we found no significant difference in tampon-test pain reduction with desipramine (t=0.90; P=.37) or lidocaine (t=1.27; P=.21). Of the remaining 12 outcome measures, only the Index of Sexual Satisfaction, improved with desipramine compared with placebo (t=-2.81; P=.006). During the open-label phase, women undergoing vestibulectomy surgery reported significantly improved pain as measured by cotton swab test and the McGill Pain Scale compared with nonsurgical alternatives. Oral desipramine and topical lidocaine, as monotherapy or in combination, failed to reduce vulvodynia pain more than placebo. Placebo or placebo-independent effects are behind the substantial pain improvement seen in all treatment allocations. ClinicalTrials.gov, www.clinicaltrials.gov, NCT00276068. I.

Posttraumatic Symptoms, Marital Intimacy, Dyadic Adjustment, and Sexual Satisfaction among Ex-Prisoners of War

The aversive impact of combat and combat-induced posttraumatic stress disorder (PTSD) on marital intimacy and sexual satisfaction has been examined in several studies. Nevertheless, the toll of war captivity on marital intimacy in relation to dyadic adjustment and sexual satisfaction remains unknown. In particular, the mediating role of marital intimacy in the relationship between PTSD symptoms and dyadic adjustment and between PTSD symptoms and sexual satisfaction has not yet been systematically explored thus far. Aims. This study aimed to examine the interrelationships of PTSD symptoms, dyadic adjustment, sexual satisfaction, and marital intimacy among ex-prisoners of war (ex-POWs). A sample of Israeli veterans ex-POWs (ex-POWs: N = 105) from the 1973 Yom Kippur War and a matched comparison group of veterans who participated in the same war but were not held captive (control: N = 94) were compared in the study variables. The PTSD inventory, dyadic adjustment scale, index of sexual satisfaction, and capacity for intimacy questionnaire. Results. Findings revealed that ex-POWs reported higher levels of PTSD symptoms and lower levels of dyadic adjustment and sexual satisfaction than comparable controls. There were also differences between the groups in the pattern of relations between PTSD symptoms, dyadic adjustment, sexual satisfaction, and marital intimacy. Finally, for ex-POWs, marital intimacy partially mediated the relationships between PTSD symptoms and dyadic adjustment and sexual satisfaction outcome measures. PTSD symptoms are implicated in marital problems of ex-POWs. A significant relationship was found between the traumatized ex-POW's capacity for intimacy and both their sexual satisfaction and dyadic adjustment.

Sexual function changes after transurethral plasmakinetic resection of the prostate

Objective To investigate the influence of transurethral plasmakinetic resection of the prostate(PKRP)on sexual function. Methods From January 2007 to December 2007.165 patients received PKRP,who had sexual active and completed the follow-up data forms before and after surgery.The average age of this cohort was 71 years(from 55 to 79 years).The average history of disease was 5.5(3-15)years while the average prostate volume 57(33-82)g,IPSS(26.4±2.6),quality of lire score(5.54±0.50),the maximum flow rate(7.04±4.10)ml/s,the average residual 120(55～250)ml.45 cases were complicated with urinary retention,and bladder stones 45 cases.15 cases with prostate stones.Their sexual function was assessed by the international index of erectile function,ejaculation function and sexual satisfaction before and 6 months after surgery by questionnaires,and compared the respective scores using SPSS14.0 and χ2 test. Results All of 165 patients,the IIEF-5 improved from(23.4±4.7)point to(24.1±4.9)point 6 months after operation(P>0.05),there was not significant.The abnormal ejaculation rate increased from 18.8%(31/165 patients)to 75.2%(124/165 patients)(P<0.001)after PKRP,respectively.The retrograde ejaculation rate increased from 11.6% (19/165 patients) to 64.2%(106/165 patients) after PKRP, respectively.There was a significant difference.128 patients (77.6 % ) and 132 patients (80.0 % ) were satisfied with their sexual active before and after 6 months PKRP, respectively. Conclusions The results of this study confirmed that PKRP has no negative influence on the quality of erections measured by IIEF-5.The loss of ejaculatory function has no influence on patients sexual active. Key words: Benign prostate hyperplasia; Transurethral plasmakinetic resection of the prostate; Sexual function

Sexual and Relationship Satisfaction among Persons with Young-Onset Parkinson's Disease

Parkinson's disease (PD) presents unique personal and social challenges, particularly for those with onset before the age of 50 years. The aim of this article is to evaluate sexual and non-sexual aspects of relationship satisfaction among persons with young-onset PD and their partners. The main outcome measures were Index of Sexual Satisfaction (ISS) and Golombok-Rust Inventory of Marital State (GRIMS). Persons with PD (PWP) and partners who attended the 2005 National Parkinson Foundation Young Onset Network Conference were asked to complete a survey. Each survey included demographics, a clinical history questionnaire, the Beck Depression Inventory (BDI), ISS, and GRIMS. Sixty PWP (63% men, 85% in a relationship) responded to the survey. Median age was 50 years (range 29-62), with a median age at symptom onset of 43 years (range 17-55). ISS scores indicated clinically significant sexual dissatisfaction in 37%. Relationship dissatisfaction measured by the GRIMS was scored as "poor" or worse in 57%. Depressive symptomatology was severe in 19% and mild in 33%. Sexual dissatisfaction (ISS) correlated with relationship dissatisfaction (GRIMS) (correlation coefficient [CC] = 0.58, P < 0.001). Relationship dissatisfaction (GRIMS) correlated with depressive symptomatology (BDI) (CC = 0.38, P = 0.007). No correlations were found with any demographic or disease characteristics. Thirty-two couples (both the PWP and their partner) completed the surveys. Sexual and relationship dissatisfaction among PWP paralleled that of their partner (ISS: CC = 0.48, P = 0.005; GRIMS: CC = 0.61, P < 0.001). Depressive symptomatology of the PWP correlated with their partners' relationship dissatisfaction (CC = 0.46, P = 0.010). In this study, sexual and relationship dissatisfaction were prevalent among young-onset PD patients. PD patients were similar to their partners in their level of sexual and relationship dissatisfaction. The degree of dissatisfaction did not correlate with demographics or self-reported disease characteristics. Self-reported depressive symptomatology among PD patients was adversely associated with both their and their partner's relationship satisfaction. Wiel

Evaluation of Marital and Sexual Interactions of Polish Infertile Couples

The World Health Organization defines infertility as inability to conceive despite regular sexual intercourse sustained for a period exceeding 12 months with no contraceptive methods. The aim of this study was to evaluate the effect of infertility on marital and sexual interactions among infertile couples. Two hundred six infertile couples were qualified to the study as the research group. The control group consisted of 190 fertile couples. A specific questionnaire was used as a research tool in this study. It included the sociodemographic part, infertility status, and validated scales: Polish version of Index of Marital Satisfaction and Index of Sexual Satisfaction. Statistica 6.0 (Medical University of Silesia; Katowice, Poland) was used in the statistical analysis. The statistical analysis made use of: Mann-Whitney U-test, chi-square with Yates' continuity correction, ancova log-linear analysis of covariance, and logistic regression analysis. The study showed a significantly better partner relationship in female infertile as compared with female fertile. Clinically significant disorders of partnership stability were observed in 11.65% of studied women and in 20% of controls. Marital adjustment and sexual satisfaction were comparable among male groups. The probability of marital disorders increased with: age above 30 (odds ratio [OR] = 1.6), female sex (OR = 1.5), and lower education (OR = 1.7) among the study population. Diagnosed male factor and infertility duration of 3-6 years were connected with the highest relationship instability and the lowest sexual satisfaction both in female and male infertile. The risk factors of marital dissatisfaction in infertility include: female sex, age over 30, lower education level, diagnosis of male infertility, and infertility duration of 3-6 years.

Decline in Sexual Functioning Over a 3-Year Period after Hematopoietic Cell Transplantation (HCT): Gender-Specific Impact of Total Body Irradiation (TBI) and Chronic Graft-Versus-Host Disease (cGvHD)

Sexual dysfunction is a multidimensional problem caused by both physiologic and psychosocial factors. Yet little is known about the longitudinal trends of sexual functioning in HCT survivors, or the clinical or psychosocial factors associated with decline. Using a longitudinal study design, we administered the Derogatis Interview for Sexual Functioning (DISF-SR), the Global Sexual Satisfaction Index (GSSI), and the City of Hope-QOL instrument at 5 time points to a large cohort of patients undergoing HCT at City of Hope (COH): prior to HCT, at 6m, 1y-, 2y-, and 3y-post-HCT. DISF-SR assessed 5 domains of sexual functioning (Cognition/Fantasy, Arousal, Behavior/Experiences, Orgasm, and Drive/Relationship), and a Total score. GSSI elicited patients' subjective appraisal of sexual satisfaction. The COH-QOL instrument was used to obtain self-reported levels of anxiety, distress, depression, pain, physical strength, and sleep changes, which were converted to composite scores of mental and physical stress. Long-term trends of sexual functions were estimated using the Generalized Estimating Equation. We examined the effects of sociodemographic factors, primary diagnosis, HCT conditioning regimens, disease status at HCT, presence of cGvHD, and composite mental and physical stress levels on the longitudinal trends of DISF-SR, the Total score, and GSSI. The cohort included 312 adults (median age at HCT 48y; 56% males) undergoing autologous (n=175) or allogeneic (n=137) HCT for hematologic malignancies or severe aplastic anemia; 144 patients completed the 3y sexual survey (participation rate at 3 years=75%). GSSI (general sexual satisfaction) declined significantly after HCT (p=0.001) for both men and women, and remained depressed over the 3-y study period, with 40% reporting poor or worse sexual satisfaction level at 3y. There were no significant differences between men and women in terms of general sexual satisfaction level. However, the degree of sexual dysfunction as measured by DISF-SR was worse in women than in men for all domains, and for Total score (p<.001) at all post-HCT time points (Fig. 1A). Furthermore, assessment of DISF-SR scores revealed that while men experienced a persistent decline in satisfaction with Orgasm and Drive/Relationship (p<0.05), women did not demonstrate a significant decline in sexual function in any of the domains post-HCT. Gender-specific multivariate analyses revealed certain subgroups that were more vulnerable to a decline in sexual functions after HCT. Notably, older age (≥40y) (Fig. 1B), being married, and TBI exposure in men (Fig. 1C), and older age (≥30y) (Fig. 1D), being overweight, and greater mental and/or physical stress in women were factors identified as significantly associated with decreased sexual functioning following HCT. Although cGvHD was not directly related to DISF-SR or GSSI, presence of cGvHD was accompanied by worse mental and physical composite scores (p<0.0001). Lower mental and/or physical composite scores in turn were significantly related to lower sexual functions for all domains of DISF-SR, the Total score (Fig. 1E) and GSSI in women (p<0.05). Thus, women may be vulnerable to the effects of cGvHD mediated through mental and/or physical stress, in turn resulting in compromised sexual functions and satisfaction after HCT. This study should inform healthcare providers that patients undergoing HCT require more attention to their sexual QOL within the first year after HCT. Routine inquiry of patients' sexual health should be included in follow-up exams after HCT, especially for those at high risk (i.e. TBI-exposed men and those with cGvHD), with the ability to offer a multidisciplinary approach to managing this distressing complication. [Display omitted]

T08-P-10 Validation of Index of Sexual Satisfaction (ISS) for use with Portuguese women

The ISS is a 25- item scale developed as an unidimensional self- rate scale with the aim of assessing problems in sexual satisfaction. In this validation after translating the ISS to Portuguese we used a community sample of 152 women (age range 26-70; Mean age= 41; SD± 12) and a clinical sample of 37 women ( age range 48-69; Mean age= 58; SD± 5) to demonstrate the psychometric properties of the Portuguese version of this scale for use with women. An item analysis was performed using SPSS 14 considering the median, the minimum and maximum value, and the skewness and kurtosis. Items 5, 15, 18, and 20 were excluded because of the non acceptable values obtained (e.g., skewness and kurtosis> 2). An exploratory factor analysis was conducted using the Principal Components Method with Varimax rotation, which demonstrated a uni- dimensional structure, and item 13 was excluded because it saturated less than.30. We analysed Cronbach's alfa, which was alfa= .95, the average inter-item correlation, which was r= .48, and the corrected item-total correlations, which ranged from r=.30 to r=.82. We analysed also the convergent validity of the ISS with FSFI and it's domains (FSFI; Rosen et al., 2000), which ranged from a minimum of r =.38 for the pain domain to a maximum of r=.69 for the satisfaction domain, and a value of r=.65 for the full scale.Portuguese clinicians and researchers now have a valid and reliable psychometric instrument to evaluate sexual satisfaction problems in Portuguese women.