Increased Health Risks Research Articles

The Correlation between Waist Circumference and Cognitive Function in Type II Diabetic Mellitus Patients in the Work Area of the Sedayu 2 Health Center Bantul

Background: The prevalence of diabetes mellitus continues to increase every year, the increase in cases of diabetes mellitus that increases occurs in many people with changes in consumption patterns of high fat and low physical activity habits, so that problems of motion tend to be overweight and obese. Obesity has strong relationship with diabetes mellitus, particularly in type 2 diabetes. Obesity occurs when excessive fat accumulation increases health risks. Increased body fat mass, and excessive central fat can lead to an increased risk of vascular and metabolic disorders which are risk factors for cognitive decline. Aims: To identify the relationship between waist circumference and cognitive function in type II DM patients in the Work Area of ​​the Sedayu 2 Health Center, Bantul. Methods: This is quantitative study with a cross-sectional design. The population in this study were respondents with type 2 diabetes mellitus aged 45 years with a simple random sampling of 110 samples. The instruments of this research used the midline and MMSE (Mini-Mental State Exam) questionnaire. Results: This study using Kendall's tau correlation analysis with 110 respondents showed that there was a significant relationship between waist circumference and cognitive function in type II DM patients in the working area of ​​the Sedayu 2 Bantul Public Health Center. The results of analysis showed a p-value of 0.000 (<0.05).Conclusion: There is a significant relationship between waist circumference and cognitive function in type II DM patients in the working area of ​​the Sedayu 2 Health Center, Bantul.

Increasing Health Risks During Outdoor Sports Due To Climate Change in Texas: Projections Versus Attitudes.

Extreme heat is a recognized threat to human health. This study examines projected future trends of multiple measures of extreme heat across Texas throughout the next century, and evaluates the expected climate changes alongside Texas athletic staff (coach and athletic trainer) attitudes toward heat and climate change. Numerical climate simulations from the recently published Community Earth System Model version 2 and the Climate Model Intercomparison Project were used to predict changes in summer temperatures, heat indices, and wet bulb temperatures across Texas and also within specific metropolitan areas. A survey examining attitudes toward the effects of climate change on athletic programs and student athlete health was also distributed to high‐school and university athletic staff. Heat indices are projected to increase beyond what is considered healthy/safe limits for outdoor sports activity by the mid‐to‐late 21st century. Survey results reveal a general understanding and acceptance of climate change and a need for adjustments in accordance with more dangerous heat‐related events. However, a portion of athletic staff still do not acknowledge the changing climate and its implications for student athlete health and their athletic programs. Enhancing climate change and health communication across the state may initiate important changes to athletic programs (e.g., timing, duration, intensity, and location of practices), which should be made in accordance with increasingly dangerous temperatures and weather conditions. This work employs a novel interdisciplinary approach to evaluate future heat projections alongside attitudes from athletic communities toward climate change.

Combined ingestion of polystyrene microplastics and epoxiconazole increases health risk to mice: Based on their synergistic bioaccumulation in vivo.

Microplastic and pesticide are two common environmental pollutants whose adverse effects have been widely reported, but it is unclear whether they cause combined toxicity in mammals. In this study, polystyrene microplastics (5µm, 0.012 or 0.120mg/kg) or/and epoxiconazole (0.080mg/kg) were administered orally to mice for 6weeks, their toxicity to liver and kidney was assessed from changes in histopathology, tissue function, oxidative defense system and metabolic profile. In addition, mechanism of combined toxicity was explored in terms of bioaccumulation levels, intestinal barrier, gut microbiota. Results showed that combined ingestion of polystyrene (0.120mg/kg) and epoxiconazole caused more severe tissue damage, dysfunction, oxidative stress, and metabolic disorders compared to single exposure sources. Interestingly, occurrence of combined toxicity was associated with their increased accumulation in tissues. In-depth exploration found that epoxiconazole caused intestinal barrier damage by targeting the gut microbiota, leading to massive invasion and accumulation of polystyrene, which in turn interfered with the metabolic clearance of epoxiconazole in liver. In all, findings highlighted that polystyrene and epoxiconazole could cause combined toxicity in mice through the synergistic effect of their bioaccumulation in vivo, which provided new reference for understanding the health risks of microplastics and pesticides and sheds light on the potential risk to humans of their combined ingestion.

Temperature modulation of adverse consequences of ozone exposure on cardiovascular mortality: A study of multiple cities in China

Worldwide epidemiological studies indicate that the adverse health effects associated with ozone exposure might be modified by ambient temperature. In China, the health risks associated with ozone exposure are poorly understood due to the lack of data. In addition, it is insufficient how temperature modifies the ozone exposure-cardiovascular mortality association. In this study, we adopted two advanced time-series Poisson generalized additive models (GAMs) including a nonparametric bivariate response surface model and a stratification parametric model to investigate the modification effect of temperature on ozone-related cardiovascular mortality in 13 cities in China from 2014 to 2016. We categorized temperature into three levels (low, moderate, and high) considering four temperature percentiles, including the 25th and 75th, 15th and 85th, 10th and 90th, and 5th and 95th temperature percentiles. Subsequently, under different temperature stratifications, we evaluated acute cardiovascular mortality risks associated with the maximum 8-h average ozone concentration (O3-8hmax) in each city and assessed these O3-8hmax-cardiovascular mortality associations by meta-analysis in all cities together. The results confirmed that high temperature strongly increased the O3-8hmax cardiovascular mortality association; in particular, the O3-8hmax mortality risk was highest when the 95th temperature percentile cut-off was applied. On days with daily mean temperatures exceeding the city-specific 75th, 85th, 90th, and 95th percentiles, a 10-μg/m3 increase in the O3-8hmax during the current and previous day (lag01) increased the cardiovascular mortality risk by 0.74%, 0.76%, 0.80%, and 1.11%, respectively. However, the O3-8hmax mortality risk did not change appreciably under moderate or cold temperature conditions defined by different temperature cut-offs. Our findings validate the theory that high temperature increases health risks associated with the O3-8hmax; thus, mitigating ozone exposure will be of utmost importance, especially under the context of a changing climate.

Disparities in Healthcare Utilization: Superfund Site vs. Neighboring Comparison Site.

Inequities in pollution-attributable health disparities are similar in most urban areas throughout the United States, and appear to encompass racial and socio-demographic differences, thereby suggesting increased health risks for those living in these areas. Individuals residing in close proximity to Superfund sites, predominantly people of color, are increasingly stricken with lung diseases. The prevalence of chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), asthma in children, and lower respiratory tract infections (LRTI), is significantly higher in the affected area compared to the neighboring control area, irrespective of smoking, socio-economic status, or demographics. We conducted a retrospective analysis using data collected from patients who obtained healthcare from the University of Alabama at Birmingham (UAB) Health System. The data were procured from the Enterprise Data Warehouse (UAB Informatics for Integrating Biology and the Bedside (i2b2)). We evaluated healthcare utilization and classification of disease (defined by ICD-10 codes) of patients residing in zip codes: affected (35207, 35217) and neighboring comparison (35214). The results of the analysis may provide evidence that can be used for risk mitigation strategies or outreach education campaign(s) for those who live in the affected area.

Sociodemographic and Clinical Characteristics Associated With Recent Incarceration Among People With HIV, United States, 2015-2017.

We examined sociodemographic, clinical, and behavioral factors associated with previous incarceration among people with diagnosed HIV to inform HIV care efforts for this population. We used 2015-2017 data from a cross-sectional, nationally representative sample of US adults with diagnosed HIV (N = 11 739). We computed weighted percentages and 95% CIs to compare the characteristics of people with HIV incarcerated in the past 12 months (ie, recently) with people with HIV not recently incarcerated. We used adjusted prevalence ratios (aPRs) with predicted marginal means to examine associations between selected factors and incarceration status. Adults with HIV who were recently incarcerated, when compared with those who were not, were more likely to be aged 18-29 years (prevalence ratio [PR] = 2.51), non-Hispanic Black (PR = 1.39), less educated (<high school diploma; PR = 1.41), unemployed (PR = 1.32), or living at or below the federal poverty level (PR = 1.64); to have recently experienced homelessness (PR = 4.56); and to have recently used drugs (PR = 1.68). Clinically, they were more likely to have been diagnosed with HIV in the past 5 years (aPR = 1.26), have lower CD4 counts (aPR = 1.45), have recently used the emergency department (aPR = 1.15), and have experienced severe anxiety (aPR = 1.50) and less likely to be retained in care, be recently virally suppressed, or have sustained viral suppression. Among people with HIV, recent incarceration was associated with increased health risks and worse health outcomes. Pre- and postrelease linkage-to-care interventions and reentry services might improve the health of recently incarcerated people with HIV.

A systematic review of working conditions and occupational health in home office.

BACKGROUND:In times of the COVID-19 pandemic, employees around the world may be practicing part-time telework at home. Little is known about the working conditions at home and its impact on the employee’s occupational health.OBJECTIVE:This systematic review examines the working conditions at employees’ homes, the work-related disorders associated with working from home, organizations’ perceptions of ergonomics at home and how they support their teleworkers.METHODS:A search of electronic databases (Cochrane Library, Embase, Medline, Google Scholar, Open Grey, Pedro, PsychInfo, PubPsych, Scopus and Web of Science) was performed. Twelve studies were included in this review.RESULTS:The findings highlight the lack of ergonomic working conditions for home-based teleworkers. Furthermore, the results underline organizations’ lack of awareness regarding home-based policies, ergonomics programs and the health-related consequences associated with the absence of ergonomic support.CONCLUSION:These findings suggest that home-based teleworkers have increased health risks. This assumption is substantiated by the fact that most of the included studies reported teleworkers who have experienced musculoskeletal issues. These results underline the necessity for implementing ergonomic design recommendations, especially for working at home. Further research is needed to understand the impact of ergonomics programs and workplace design for working at home.

The Reshaping of the E-Cigarette Retail Environment: Its Evolution and Public Health Concerns.

E-cigarette use represents a public health controversy in the US and globally. Despite the potential of e-cigarettes to support cigarette cessation, their use increases health risks and risk for addiction, particularly in young people. Various federal, state, and local laws have impacted tobacco retail in general and e-cigarettes in particular. In the US, 2019–2020 federal laws increased in the minimum legal sales age for tobacco to 21 and banned flavored cartridge-based e-cigarettes. Many states and localities were early adopters of Tobacco 21 and implemented more comprehensive flavor restrictions than the federal ban. Meanwhile, cannabis retail is increasingly being legalized in the US—while cannabis-based product regulation has notable gaps at the federal, state, and local levels. These regulatory complexities have impacted specialized retailers selling e-cigarettes, including “vape shops” that exclusively sell e-cigarettes, “smoke shops” that sell e-cigarettes and other tobacco (and potentially CBD/THC and other un- or under-regulated products), and online retail. This commentary outlines public health concerns related to: (1) youth access; (2) consumer exposure to a broader range of tobacco products and marketing in retail settings where they may seek products to aid in cigarette cessation (i.e., such broad product exposure could hinder cessation attempts); (3) consumer exposure to un-/under-regulated products (e.g., delta-8-THC, kratom); and (4) federal, state, and local regulations being undermined by consumer access to prohibited products online and via the mail. These concerns underscore the need for ongoing surveillance of how retailers and consumers respond to regulations.

Do public employment services affect the self-rated health of migrant workers in China?

Migrant workers greatly contributing to China’s industrialization and urbanization are confronted with increasing health risks. This study empirically investigates the effects of public employment services on the self-rated health of migrant workers in Shanghai China, by using data from the National Bureau of Statistics from 2015 to 2020. The estimation results under the Ordered Probit model illustrate that public employment services significantly improve the self-rated health of migrant workers, and vocational training, job development and other related services show an apparently positive correlation with the self-rated health. The marginal effect analysis reveals that public employment services obviously reduce the probability of health satisfaction as “average”, “relatively satisfied” and “relatively dissatisfied”, which translate into a significant increase in the probability of “very satisfied”. The mechanism analysis verifies that public employment services enhance the self-rated health by increasing the proportion of medical insurance and injury insurance of migrant workers. The results are still reliable by adopting the methods of subsample regression, Propensity Score Matching and variable substitution to conduct robustness checks. This study further enriches the literature on public employment services and the health status of migrant workers, and provides policy implications on improving the health status of migrant workers and the public employment service system of China under the impact of the COVID-19 pandemic.

Barriers and facilitators to opioid agonist treatment (OAT) engagement among individuals released from federal incarceration into the community in Ontario, Canada

ABSTRACT Introduction Correctional populations with opioid use disorder experience increased health risks during community transition periods. Opioid Agonist Treatment (OAT) can reduce these risks, but retention is a key challenge. This study addresses a knowledge gap by describing facilitators and barriers to OAT engagement among federal correctional populations released into the community in Ontario, Canada. Methods This article describes results from a longitudinal mixed-methods study examining OAT transition experiences among thirty-five individuals released from federal incarceration in Ontario, Canada. Assessments were completed within one year of participants’ release. Data were thematically analyzed. Results The majority (77%) of participants remained engaged in OAT, however, 69% had their release suspended and 49% returned to custody. Key facilitators for OAT engagement included flexibility, positive staff rapport, and structure. Fragmented OAT transitions, financial OAT coverage, balancing reintegration requirements, logistical challenges, and inaccessibility of ‘take-home’ OAT medications were common barriers. Conclusions Post-incarceration transition periods are critical for OAT retention, yet individuals in Ontario experience barriers to OAT engagement that contribute to treatment disruptions and related risks such as relapse and/or re-incarceration. Additional measures to support community OAT transitions are required, including improved discharge planning, amendments to OAT and financial coverage policies, and an expansion of OAT options.

Anti-Inflammatory Food in Asthma Prepared from Combination of Raphanus sativus L., Allium hookeri, Acanthopanax sessiliflorum, and Dendropanax morbiferus Extracts via Bioassay-Guided Selection.

Asthma is a highly prevalent inflammatory disease of the respiratory airways and an increasing health risk worldwide. Hence, finding new strategies to control or attenuate this condition is necessary. This study suggests nutraceuticals that are a combination of herbal plant extracts prepared from Acanthopanax sessiliflorum (AS), Codonopsis lanceolate (CL), Dendropanax morbiferus (DM), Allium hookeri (AH), and Raphanus sativus L. (RS) that can improve immunomodulatory ability through the detoxification and diuresis of air pollutants. Herbal parts (AH whole plant, RS and CL roots, AS and DM stems, and DM leaves) were selected, and four types of mixtures using plant extracts were prepared. Among these mixtures, M2 and M4 exhibited antioxidant activities in potent 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) and 1,1-diphenyl-β-picrylhydrazine (DPPH) radical assays. Moreover, M4 exhibited a marked increase in glutathione S-transferase (GST) activity and significantly inhibited the inflammatory mediator, nitric oxide (NO) and proinflammatory cytokines, interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α generation. Furthermore, M4 exhibited the strongest antioxidant, hepatoprotective, and anti-inflammatory effects and was selected to prepare the product. Before manufacturing the product, we determined that the active mixture, M4, inhibited gene expression and generation of proinflammatory cytokines IL-1β, IL-6 and TNF-α in ovalbumin (OVA)-, lipopolysaccharide (LPS)-, and particulate matter (PM)-induced asthmatic rat models. The granular product (GP) was manufactured using M4 along with additives, i.e., lactose, oligosaccharide, stevioside extract, and nutmeg seed essential oils (flavor masking), in a ratio of 1:4 using a granulation machine, dried and ultimately packaged. The GP inhibited the generation of proinflammatory cytokines IL-1β, IL-6 and TNF-α in OVA-, LPS- and PM-induced asthmatic rat models. These results suggest that GP prepared from a combination of herbal plants (AS, CL, DM, AH and RS) is a potent functional food with anti-inflammatory activity that can be used to treat asthma caused by ambient air pollutants.

The COVID-19 pandemic and residential mobility intentions in the United States: Evidence from Google Trends data.

The COVID‐19 pandemic has disrupted people's lives through economic challenges, closure of worksites and schools and increased health risks. These disruptions can trigger new residential needs and preferences, but little research has been done regarding the impact of the COVID‐19 pandemic on moving intentions. We theorized how the pandemic could influence intentions of making different types of residential moves. Using Google Trends data, we conducted a time‐series analysis to assess the transitory, short‐term and long‐lasting changes in various types of mobility intentions since the pandemic. Results show that thoughts about temporary relocation surged at the onset of the COVID‐19 epidemic and then experienced a long‐term decrease. Intentions to move through housing purchases and rentals briefly declined at the beginning of the pandemic but then surpassed their normal levels in the following months. Thoughts about moving in with family or parents increased by almost 50% during the pandemic. These trends were also reflected in Google searches for moving services, which exhibited an initial decline followed by a long‐term increase. The results demonstrate that the COVID‐19 pandemic has not only posed obstacles that lowered moving intentions but also has created new needs and desires for moving.

One Vax Two Lives: a social media campaign and research program to address COVID-19 vaccine hesitancy in pregnancy

The COVID-19 pandemic has disproportionately affected pregnant people by increasing health risks of maternal morbidity and mortality, stillbirth, and preterm birth. Although numerous studies have supported the safety and efficacy of COVID-19 vaccination in pregnancy in preventing or mitigating the risk for these adverse outcomes, many pregnant people remain hesitant. Approximately half of US adults regularly consume news from social media platforms, which are a fertile ground for the spread of vaccine disinformation. The lack of information regarding COVID-19 vaccine safety early in the pandemic fueled vaccine myths targeting the fears of pregnant people about vaccination risks. Saddened by the spike in maternal deaths of unvaccinated individuals during the COVID-19 Delta variant surge in the fall of 2021, we created a social media campaign to promote scientific communication regarding the risks of COVID-19 disease in pregnancy and the benefits of vaccination. We called the campaign “One Vax Two Lives,” which refers to the ability of 1 maternal vaccine to benefit the health and lives of both the pregnant individual and their fetus. We present a blueprint of how we leveraged a large, interdisciplinary student workforce to create a social media campaign and research program studying vaccine hesitancy, which can be replicated by other groups. Community engagement and partnerships with key stakeholders, such as the Washington State Department of Health, were essential for amplifying the campaign and providing our team with feedback on content and approach. We present the analytics of our social media advertisements, web articles, and video content that helped inform the iterative design process of the multimedia content. Moving forward, we are launching collaborative research programs to study vaccine hesitancy and inform the development of new social media content designed for pregnant individuals who are: (1) Spanish-speaking Hispanic/Latina/x, (2) Black or Afro-Latinx, and (3) residents of rural communities in the State of Washington. Data from these mixed methods studies will inform new communication campaigns to reach vaccine-hesitant individuals. Finally, we discuss lessons learned and how the most impactful elements of the campaign can be translated to related areas of maternal public health.

Gluten-Free Cereals and Pseudocereals as a Potential Source of Exposure to Toxic Elements among Polish Residents.

Background: Nutritional food quality plays a crucial role in maintaining human health. However, food and drinking water, along with occupational exposure, are the main routes of exposure to toxic elements for humans. The main aim of this study was to determine the content of As, Cd, Pb and Hg in naturally gluten-free grains and products made from buckwheat, millet, maize, quinoa and oat. The safety of consumption of the products tested was also assessed. Methods: The contents of As, Cd and Pb were determined using inductively coupled plasma mass spectrometry (ICP-MS). To measure Hg, an atomic absorption spectrometry method (AAS) with the amalgamation technique was applied. To assess the level of consumption of the tested products, an online survey was conducted. To estimate health risk, three indicators were used: the target hazard quotient (THQ), cancer risk (CR) and hazard index (HI). The research material obtained 242 different samples without replications. Results: The highest average content of As, Cd, Pb and Hg were observed for the following groups of products: oat (10.19 µg/kg), buckwheat (48.35 µg/kg), millet (74.52 µg/kg) and buckwheat (1.37 µg/kg), respectively. For six samples, exceedance of established limits was found—three in the case of Cd and three of Pb. Due to the lack of established limits, As and Hg content of the tested products was not compared. Generally, no increased health risks were identified. Conclusions: Based on the obtained results, the consumption of gluten-free cereals and pseudocereals available on the Polish market seems to be safe. However, there is a great need to establish maximum levels of the toxic elements, especially As and Hg in cereal products in European legislation.

Expert consensus recommendations on the use of randomized clinical trials for drug approval in psychiatry- comparing trial designs

The use of randomized clinical trials, in particular placebo-controlled trials, for drug approval, is the subject of long-standing debate in the scientific community and beyond. This study offers consensus recommendations from clinical and academic experts to guide the selection of clinical trial design in psychiatry. Forty-one highly cited clinical psychiatrists and/or researchers participated in a Delphi survey. Consensus statements were developed based on the findings of a published, peer-reviewed systematic review. Participants evaluated statements in two survey rounds, following the Delphi method. The expert panel achieved consensus on 7 of 21 recommendations regarding the use of randomized clinical trials. The endorsed recommendations were: (i) Results from placebo-controlled trials are the most reliable and (ii) are necessary despite the growing placebo-effect; (iii) it is ethical to enroll patients in placebo-arms when established treatment is available, if there is no evidence of increased health risk; (iv) There is a need to approve new drugs with the same efficacy as existing treatments, but with different side-effect profiles; (v) Non-inferiority trials incur an increased risk of approving ineffective medications; (vi) The risk of approving an ineffective drug justifies trial designs that incur higher costs, and (vii) superiority trials incur the risk of rejecting potentially efficacious treatments. The endorsed recommendations inform the choice of trial-design appropriate for approval of psychopharmacological drugs. The recommendations strongly support the use of randomized clinical trials in general, and the use of placebo-controlled trials in particular.

A Critical Review on Assessment of Karna Roga Nidana in Present Lifestyle

Hearing is one of our most important senses. It enables us to steer our existence without limitations and helps us to socialize, work and communicate with the world. Similarly, our ancient system of medicine has also given importance to Panchendriya among which Karna is the one responsible for perception of sound. The present-day lifestyle adopted by man is the way of living that helps him to enjoy more aspects of life. These patterns of individual practices and behavioral choices have increased health risks. Majority of ear disorders result due to these inappropriate habits. As prevention is better than cure, Ayurveda helps in understanding causative factors according to modern lifestyle and ways to prevent it. Hence this work aims to critically review causatives of Karnaroga from all available literatures of Ayurveda and establish a link with modern lifestyle causing aural pathogenesis.

Methodological approach to assessing environmental risk (health risk) from air pollution in the Baikal region in a changing climate

The methodological approach to assessing the environmental risk (health risk) from atmospheric pollution in the Baikal region taking into account the changing climate was formulated. It is based on the US EPA's health risk assessment methodology and impurity concentration estimates by solving the adjoint equation for impurities transport and diffusion. The dynamics of health risk for the population of Irkutsk from atmospheric pollution PM10, PM2.5 due to emissions from possible sources located both in the Baikal region and beyond including sources of transboundary pollution in 1980-2050 under various scenarios of climate change was researched. A tendency for a moderate decrease in the considered risk over the past several decades was shown. In the forecast period until 2050, under both climate scenarios, significant changes in the risk were not noted. The spatio-temporal dynamics of the areas of PM10, PM2.5 sources location that create the increased health risk in relation to Irkutsk was studied. The results indicate the moderate narrowing of the increased risk zone for Irkutsk in the first half of the 21st century. In the period until 2050, the main impact on the population health in the Irkutsk area from emission sources located in the southwest, south and southeast is expected. In case of transboundary pollution, the main danger from sources in Kazakhstan, Mongolia, and China is expected. The results are important to develop proposals for ensuring safety for public health, developing health care and planning environmental protection measures in the Baikal and neighboring regions.

Depuration of live oysters to reduce Vibrio parahaemolyticus and Vibrio vulnificus: A review of ecology and processing parameters.

Consumption of raw oysters, whether wild-caught or aquacultured, may increase health risks for humans. Vibrio vulnificus and Vibrio parahaemolyticus are two potentially pathogenic bacteria that can be concentrated in oysters during filter feeding. As Vibrio abundance increases in coastal waters worldwide, ingesting raw oysters contaminated with V. vulnificus and V. parahaemolyticus can possibly result in human illness and death in susceptible individuals. Depuration is a postharvest processing method that maintains oyster viability while they filter clean salt water that either continuously flows through a holding tank or is recirculated and replenished periodically. This process can reduce endogenous bacteria, including coliforms, thus providing a safer, live oyster product for human consumption; however, depuration of Vibrios has presented challenges. When considering the difficulty of removing endogenous Vibrios in oysters, a more standardized framework of effective depuration parameters is needed. Understanding Vibrio ecology and its relation to certain depuration parameters could help optimize the process for the reduction of Vibrio. In the past, researchers have manipulated key depuration parameters like depuration processing time, water salinity, water temperature, and water flow rate and explored the use of processing additives to enhance disinfection in oysters. In summation, depuration processing from 4 to 6days, low temperature, high salinity, and flowing water effectively reduced V. vulnificus and V. parahaemolyticus in live oysters. This review aims to emphasize trends among the results of these past works and provide suggestions for future oyster depuration studies.

Menopause care and over the counter vaginal oestradiol

Menopause care is receiving more attention than ever before in the UK and has been highlighted as a priority area in the upcoming Women's Health Strategy for England and through the work of the UK Menopause Taskforce.1 These efforts bring an opportunity to increase access to menopause support, information, and treatment, which for many years has been hampered by a legacy of fear of hormone replacement therapy (HRT) after the publication of the Women's Health Initiative study in 2002.2 This study reported increased health risks associated with HRT and was accompanied by widespread negative media coverage, followed by a decrease in HRT use worldwide.

Consumption of Energy Drinks in Medical Students of Nowsera Medical College

Background: Young adults use energy drinks that have high caffeine levels. Higher consumption will increase health risk. Effects of different ingredients on health need to be investigated. Consumption of energy drinks has become popular in students but there has been little research regarding energy drink consumption patterns in college students in Pakistan. Aim: To determine energy drink consumption patterns in college students, prevalence and frequency of energy drink use and the perception of students about benefits and hazards of energy drinks consumption. Methods: A cross sectional study was conducted on total of 180 medical students of Nowshera from all years of medical course from Jan 2019 to Dec 2019. 180 medical students were selected through convenient sampling technique. After obtaining verbal consent the data were collected using a self-administered, closed ended questionnaire and analyzed by using SPSS version 20. Results: Frequency of energy drinks consumption was found to be 110(61.1%) in a sample of 180 medical students of MBBS. Sting was the most common brand consumed 73.33% consumed by them. The major reasons reported for its usage were to gain/replenish energy and boost stamina by 46(29.8%), and studying for examination by 25(16.2%). Advertisement 24(15.5%) was reported as the major source of information followed by friends 47(30.5%). Significant differences were found between usage of energy drinks with gender (&lt;0.001), i.e., 79(71.8%) males and 31(28.2%) females. Conclusion: Consumption of energy drinks, despite the variation in the reason for choosing such drinks, is quite common in college students. Consumption rate was high in male gender (63.9%). The main reasons for consumption were to gain/replenish and boost energy and to increase the concentration in studies. A greater percentage (54.6%) of the students were aware of the adverse effects of energy drinks consumption. Keywords: Energy drinks, Health risk, Consumption, Energy, Socioeconomic status