With increasing health awareness, monitoring human physiological signals for health status and disease prevention has become crucial. Non-invasive flexible wearable devices address issues like invasiveness, inconvenience, size, and continuous monitoring challenges in traditional devices. Among flexible sensors, optical fiber sensors (OFSs) stand out due to their excellent biocompatibility, anti-electromagnetic interference capabilities, and ability to monitor multiple signals simultaneously. This paper reviews the application of flexible optical fiber sensing technology (OFST) in monitoring human lung function, cardiovascular function, body parameters, motor function, and various physiological signals. It emphasizes the importance of continuous monitoring in personal health management, clinical settings, sports training, and emergency response. The review discusses challenges in OFST for continuous health signal monitoring and envisions its significant potential for future development. This technology underscores the importance of constant health signal monitoring and highlights the advantages and prospects of optical fiber sensing. Innovations in OFS for non-invasive continuous monitoring of physiological signals hold profound implications for materials science, sensing technology, andbiomedicine.
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