Incorrect Readings Research Articles

FrameOUT and FrameOUTDB: A web based application and repository for the identification and analysis of frameshift mutations

Frameshift, one of the three classes of recoding, leads to waste of energy, resources and activity of biosynthetic machinery. In addition, some peptides, probably cycotoxic synthesized after frameshifts, results in diseases and disorders like muscular dystrophies, lysosomal storage disorders, and cancer. Hidden Stop Codons that occur naturally in coding sequences among all organisms, are associated with the early termination of translation for incorrect reading frame selection and help to reduce the metabolic cost related to the frame-shift events. Hidden stop codons and their association with numerous diseases. These codons are associated with the early termination of translation for incorrect reading frame selection and help to reduce the metabolic cost related to the frame-shift events. There are lots of appearances of hidden stops in mitochondrial genomes and we tried to study this putative event in mitochondrial genomes of vertebrates. To reduce this gap, this work presents an algorithmic web based tool to study hidden stops in frame-shifted translation for vertebrate mitochondrial genomes through respective genetic code system. FrameOUT (FO), an algorithmic web based application, predicts mutations in a user input sequence, be it a diseased or a normal sequence by implementation of Hidden Markov Model. FODB is a collection of all available Frameshift events and their association with various diseases.

2017 WSGC Elijah High-Altitude Balloon Payload

The 2017 WSGC Elijah High-Altitude Balloon Payload Fellowship focused on three different topics for high altitude research: Modular Payload Design, Balloon Dynamics, and Energy Harvesting. A modular payload system was created using advanced manufacturing methods, which improved assembly and field operation. Minor structural fracturing was observed upon recovery. All instrumentation recovered were functioning. Vertical flight dynamics of a high-altitude balloon were studied to create a model that was compared against experimental data. Predictions did not accurately replicate GPS altitude data, possibly due to incorrect internal-balloon pressure readings and underlying assumptions. Habitability of high-altitude environments were explored by monitoring insect analog in pressurized environment. A slow pressure leak induced insects into a comatose state. Radiation was detected visually with camera.Investigated energy generation from balloon kinematics. Flight data not obtained but flight simulation data produced average voltage = 0.0039 V and total energy = 245.13 J.

On the Use of Radiosondes in Freezing Precipitation

AbstractRadiosonde observations are used the world over to provide critical upper-air observations of the lower atmosphere. These observations are susceptible to errors that must be mitigated or avoided when identified. One source of error not previously addressed is radiosonde icing in winter storms, which can affect forecasts, warning operations, and model initialization. Under certain conditions, ice can form on the radiosonde, leading to decreased response times and incorrect readings. Evidence of radiosonde icing is presented for a winter storm event in Norman, Oklahoma, on 24 November 2013. A special sounding that included a particle imager probe and a GoPro camera was flown into the system producing ice pellets. While the iced-over temperature sensor showed no evidence of an elevated melting layer (ML), complementary Particle Size, Image, and Velocity (PASIV) probe and polarimetric radar observations provide clear evidence that an ML was indeed present. Radiosonde icing can occur while passing through a layer of supercooled drops, such as frequently found in a subfreezing layer that often lies below the ML in winter storms. Events that have warmer/deeper MLs would likely melt any ice present off the radiosonde, minimizing radiosonde icing and allowing the ML to be detected. This paper discusses the hypothesis that the absence of an ML in the radiosonde data presented here is more likely to occur in winter storms that produce ice pellets, which tend to have cooler/shallower MLs. Where sounding data do appear to be compromised by icing, polarimetric radar data might be used to identify MLs for nowcasting purposes and numerical model initialization.

Tucidide, Nicia e la religione. Sulla tradizione di Th. 7, 86, 5

This paper discusses the exegetical implications of the longstanding acceptance of the incorrect reading ἐς τὸ θeῖον in the context of Thucydides famous eulogy of Nikias (VII.86.5). Included in the...

Application of Wireless Sensor Network based on LoRa in City Gas Meter Reading

At present, the common meter reading method in gas meter reading system is manual. The meter reader enters the meter reading system to calculate the cost after getting the reading. This work is not only labour-intensive, but also inefficient. In addition, incorrect reading may occur due to human errors. With the development of the wireless communication technology, a wireless communication technology named LoRa for long-distance and low-power-consumption devices appeared. LoRa is a wireless communication technology with long transmission distance, low power consumption, low transmission speed, low complexity and low cost. It is mainly used in automatic control and internet of things. Through the comparison and analysis of several wireless communication technologies, a gas meter reading platform based on LoRa spread spectrum and wireless sensors is proposed. First of all, this paper briefly introduces the LoRa wireless communication technology and machine vision technology. Secondly, it gives a detailed introduction to the overall design of the system which includes system architecture design, information acquisition terminal, image acquisition module and wireless sensor module. Finally, an experiment is carried out in a residential area. The results show that the gas meter reading platform based on LoRa and wireless sensor network has a high practical value.

Stop making sense of Bell’s theorem and nonlocality?

In a recent paper on Foundations of Physics, Stephen Boughn reinforces a view that is more shared in the area of the foundations of quantum mechanics than it would deserve, a view according to which quantum mechanics does not require nonlocality of any kind and the common interpretation of Bell theorem as a nonlocality result is based on a misunderstanding. In the present paper I argue that this view is based on an incorrect reading of the presuppositions of the EPR argument and the Bell theorem and, as a consequence, is unfounded.

Registration of reactive power for case of distortions in electric grid

Nowadays, virtually everywhere worldwide, the electricity is paid for based on active and reactive power meters. Higher harmonics appeared to influence the electric power meter readings, and this specifically relates to reactive power. Incorrect power meter readings occur due to different so-called “measuring” protection levels in device circuitry in various devices. The paper analyzes reactive power meter readings of devices from various manufacturers. Based on the analysis, the authors introduce a new approach to evaluating the costs in connection to reactive power generation, transmission and consumption, with current/voltage distortions in power supply lines.

Bambo Can Go

The author analyses Tuwim’s Bambo, the Black Boy and tries to point to a number of interpretative paradoxes that have accumulated around its multiple readings. Particular attention is paid to the racial readings of the poem. What is more, the author discusses a variety of contemporary contexts in which the famous poem functions; these are often politically incorrect readings and interpretations which make no sense of the historical context in which the work was originally written. The article offers a detailed analysis of the origins of the poem and the circumstances in which found its way to the school primer. The poem is seen as expressing the need for accepting otherness and fighting cultural stereotypes.

A 0.4 V 12T 2RW dual-port SRAM with suppressed common-row-access disturbance

Dual-port SRAMs with two sets of address bus and data IOs are widely employed in various applications to increase throughput. Conventional 8T dual-port SRAM suffers reliability issue at low voltages due to common-row-access disturbance. Specifically, a row is simultaneously accessed by two operations, which can flip existing data and cause incorrect read output. Previous work can address this stability issue by assisting circuitry at cost of timing. This paper presents a low voltage 12T 2RW SRAM featuring parallel access with suppressed disturbance to ameliorate the problem without performance degradation. The proposed SRAM cell suppresses the disturbance by separating read path from internal nodes and minimizing the probability of the worst case stability with area penalty of 6%. In addition, hierarchical bitlines and a virtual ground technique are employed to further lower the minimum operating voltage and power consumption. A 16kb SRAM has been fabricated in a 65nm CMOS technology and extended the operating voltage from super-threshold region to 0.4V at common-row-access scenario.

Assessment of frozen section margin analysis during olfactory neuroblastoma surgery.

1) assess the performance of the intraoperative frozen section procedure to correctly classify biopsies obtained during olfactory neuroblastoma (ONB) surgery; 2) define the relationship between posttest probabilities and pretest probabilities from frozen section analysis; and 3) review incorrectly classified specimens. Study of diagnostic accuracy. We searched our institution's pathology database for patients who had ONB surgery between January 1, 2000 and November 16, 2012. We only included patients who had a definitive diagnosis of ONB prior to surgery and frozen sections obtained during surgery. All frozen sections in this study had corresponding permanent sections available to serve as a gold standard. This database was analyzed to obtain classification statistics. The confidence intervals for classification performance were obtained using the bootstrap sampling method. Confidence intervals for posttest probability curves were derived using the Taylor series expansion. Finally, we obtained and reviewed the slides from ambiguous or incorrect reads. A total of 459 specimens from 33 patients were analyzed. We found the following performance characteristics: sensitivity: 0.89 (0.81, 0.94); specificity: 0.96 (0.94, 0.98); accuracy: 0.95 (0.92, 0.96); likelihood ratio positive: 24.4 (14.5, 44.1); prevalence: 0.20 (0.17, 0.25); positive predictive value: 0.86 (0.78, 0.92); and negative predictive value: 0.97 (0.95, 0.99). Histopathologic review revealed that crush artifacts and inadequate specimen size were major sources of incorrect reads. We found frozen section assessment of ONB specimens to be an excellent tool for the assessment of intraoperative margins. NA. Laryngoscope, 127:1735-1741, 2017.

Design of heart rate monitor based on piezoelectric sensor using an Arduino

Reading of result heart rate using an acoustic stethoscope needs a particular skill, quiet environment, and hearing sensitivity. This project had the purpose design of a user-friendly automatic heart rate monitor and especially in a noisy area which to eliminate problems and incorrect reading of result. The liquid crystal display shows a heart rate as a result of measurements. The design of the heart rate monitor has two main parts; the signal recorder that a piezoelectric sensor, a filter, and an amplifier as recorder. The second parts was Arduino microcontroller with reinforced. Besides, three supporting buttons provided as the manual switches, the ‘on’, the ‘start’, and ‘reset’ buttons. The values acquired from the heart rate monitor indicate that those were on the Vernier BPS-BTA value range. The measurement error factor of the heart rate monitor then compared to the Vernier BPS-BTA test device was 3.15%. Besides, the value of statistical independent-test indicates that there is no significant difference (P = 0.971) between the heart rate monitor device and the Vernier BPS-BTA. In conclusion, this device was ready to be used because it has almost the same accuracy with the standart device.

Inter- and intra-operator variability in the analysis of packed cell volume.

To identify whether inter- and intra-operator variability occurs in the measurement of canine packed cell volume and, if so, at which stage these errors occur. Undergraduate veterinary students and veterinary surgeons were recruited to measure the packed cell volumes of three samples in duplicate. Measurements from each sample were confirmed by one author, and it was then ascertained whether the error was made in the capillary preparation or reading. Data were obtained from 44 students and 11 vets. A total of 25% of students made errors associated with inadequate mixing; 23% students and 9% of vets made errors consistent with incorrect reading. There was also less intra-operator variation in values within the vet group (0·027 from the mean) in comparison to the student group (-0·21 from the mean). A total of 68·2% of students and 91% of vets filled the capillary tubes outwith World Health Organisation standards of two-thirds to three-quarters full. Packed cell volume measurement is extremely useful when measuring erythroid mass, but it is crucial that the results upon which decisions are made are accurate and precise in order to manage these cases appropriately. Operator variation is a significant factor and must be addressed by proper training and following standard operating procedures.

Quality filtering of Illumina index reads mitigates sample cross-talk.

BackgroundMultiplexing multiple samples during Illumina sequencing is a common practice and is rapidly growing in importance as the throughput of the platform increases. Misassignments during de-multiplexing, where sequences are associated with the wrong sample, are an overlooked error mode on the Illumina sequencing platform. This results in a low rate of cross-talk among multiplexed samples and can cause detrimental effects in studies requiring the detection of rare variants or when multiplexing a large number of samples.ResultsWe observed rates of cross-talk averaging 0.24 % when multiplexing 14 different samples with unique i5 and i7 index sequences. This cross-talk rate corresponded to 254,632 misassigned reads on a single lane of the Illumina HiSeq 2500. Notably, all types of misassignment occur at similar rates: incorrect i5, incorrect i7, and incorrect sequence reads. We demonstrate that misassignments can be nearly eliminated by quality filtering of index reads while preserving about 90 % of the original sequences.ConclusionsCross-talk among multiplexed samples is a significant error mode on the Illumina platform, especially if samples are only separated by a single unique index. Quality filtering of index sequences offers an effective solution to minimizing cross-talk among samples. Furthermore, we propose a straightforward method for verifying the extent of cross-talk between samples and optimizing quality score thresholds that does not require additional control samples and can even be performed post hoc on previous runs.Electronic supplementary materialThe online version of this article (doi:10.1186/s12864-016-3217-x) contains supplementary material, which is available to authorized users.

Interferences and Limitations in Blood Glucose Self-Testing: An Overview of the Current Knowledge.

In general, patients with diabetes performing self-monitoring of blood glucose (SMBG) can strongly rely on the accuracy of measurement results. However, various factors such as application errors, extreme environmental conditions, extreme hematocrit values, or medication interferences may potentially falsify blood glucose readings. Incorrect blood glucose readings may lead to treatment errors, for example, incorrect insulin dosing. Therefore, the diabetes team as well as the patients should be well informed about limitations in blood glucose testing. The aim of this publication is to review the current knowledge on limitations and interferences in blood glucose testing with the perspective of their clinical relevance.

Corrigendum

BJOG: An International Journal of Obstetrics & GynaecologyVolume 123, Issue 8 p. 1408-1408 CorrigendumFree Access Corrigendum This article corrects the following: BJOG Editor's Choice Patrick Chien, Volume 123Issue 1BJOG: An International Journal of Obstetrics & Gynaecology pages: 9-10 First Published online: December 29, 2015 First published: 07 June 2016 https://doi.org/10.1111/1471-0528.14146AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat In the following article1, there was an error in the sentence on page 9, 4th paragraph. The incorrect sentence reads: On page 58, Thornton's mini commentary also questions the generalisability of the Term Breech trial, thereby suggesting that vaginal breech delivery may be an acceptable option in selected cases (Figure 1). The sentence should read: On page 58, Thornton's mini-commentary suggests that, as the pooled relative effect size of elective caesarean section versus planned vaginal delivery from this review is similar to that observed in the Term Breech trial, the results from the review should be considered to be generalisable to other non-participating maternity units. Therefore, even if some patients may choose to have a vaginal birth, there is still an increased risk of fetal death from this mode of delivery (Figure 1).■ Reference 1Chien P. BJOG Editor's Choice. BJOG: An International Journal of Obstetrics & Gynaecology, 2016; 123: 9– 10. Volume123, Issue8July 2016Pages 1408-1408 ReferencesRelatedInformation

Conventional measuring probes in the wall layer of turbulent subsonic ducted flows

This piece of work is concerned with the application of two conventional measuring probes, pressure probe and hot wire, in the wall layer of subsonic ducted, pipe and channel, flows for velocity measurements. Careful measurements have been carried out and analysed accordingly for Reynolds number range of 2.8×105≤Rem≤4.5×105 and 4×104≤Rem≤2.3×105 for the pipe and the channel, respectively. Pressure probes of outer diameters (d 0 + = d 0·uτ/v) 20-120 wall units and hot wire, having wire length (l+= l uτ/v) of 50-250 for the current Reynolds range, have been utilized to carry out the present measurements. When the pressure probe was applied in the wall layer, the wall proximity and the shear gradient played major roles of its incorrect velocity readings, however, this effect was far from being influencing the hot-wire velocity measured in the overlap region. When the pressure probe results compared to those obtained by the hot wire, the pressure probe's data showed hump in the normalized mean velocity profiles around the wall distances y+≤300 and y+≤150 for the pipe and the channel, respectively. Available corrections are adopted and applied to the pressure probe data measured, yielding results that are comparable to those of the hot wire and this was also demonstrated by comparing the present results corrected to the so-called the logarithmic velocity profile.

CORRESPONDÊNCIA ENTRE AUTO-RELATOS E DESEMPENHOS ACADÊMICOS ANTECEDENTES EM CRIANÇAS COM HISTÓRIA DE FRACASSO ESCOLAR

Este estudo investigou variáveis controladoras de auto-relatos de crianças com história de fracasso escolar sobre desempenhos acadêmicos antecedentes e condições para produzir auto-relatos precisos, correspondentes a ações antecedentes. Quatro crianças do ciclo básico escolar participaram. “Fazer” consistiu em ler em voz alta uma palavra escrita. “Dizer” consistiu em relatar se sua leitura havia sido ou não correta. Numa condição linha de base, na ausência do experimentador e sem conseqüências contingentes à correspondência, os participantes sistematicamente relataram como corretas as suas leituras incorretas. A presença do experimentador e o reforço de correspondência foram condições efetivas para aumentar o número de relatos precisos desses desempenhos. Uma história de punição de erros, provavelmente, controlou inicialmente o auto-relato impreciso das crianças. Palavras-chave: correspondência entre dizer a fazer, fracasso escolar, auto-relato, crianças

The Realism of Political Liberalism

Recently several political theorists have argued that mainstream political theory, exemplified by John Rawls’ political liberalism, is based on such idealist and moralist presuppositions, that it cannot be relevant for real politics. This article aims to show that the criticism of these ‘realists’, as these critics are referred to, is based on an incorrect reading of Rawls’ work. The article explains that there are three ways in which his political liberalism can be said to offer a realist understanding of politics: (a) political liberalism interprets the morality inherent in engaging in politics; (b) it acknowledges reasonable disagreement about justice; and (c) it develops standards of public reason, with which to assess the legitimacy of political compromises. The article recovers the realism of political liberalism and indicates new sites of discussion between political liberals and political realists.

Современные зарубежные исследования проблемы понимания текстов младшими школьниками

In the article, the reader can observe the experience taken from foreign publications that focus on the problems of teaching primary school pupils how to understand the texts, which is one of the most important universal competences in the educational process. The author studied and analyzed the investigations of American, Finnish, Canadian, Chinese and other scientists in this field. The author found out that during the latest half of the century the quality of reading among pupils has dramatically decreased and has a tendency to get even worse. The most attention in the article was paid to the investigations that demonstrate the possible causes of incorrect reading and understanding of the informative texts among pupils. Among the causes there are: the difficulty of the text that influences the understanding of it, using different methods of teaching how to read the text, the control and evaluation of reading skills etc. In the article there are enlisted the factors that contribute to the better understanding of texts. There are also mentioned some strategies of coping with problems and forming the good reading skills. The scientific works that are mentioned in the article have a great importance in the theory and practice of pedagogical science, as the ability to understand the text correctly is not only important for successful educational process at school, but is also an essential ability in life

Prevalence of and factors associated with myopia in primary school students in the Chaoyang District of Beijing, China.

To determine the prevalence of and risk factors for myopia in primary school children in Chaoyang District, Beijing. This cross-sectional prevalence survey was conducted in September to October 2011 in 4 schools randomly chosen from among the 126 primary schools in Chaoyang District. Students were assessed with autorefractometry under cycloplegia and checked with retinoscopy for accuracy. Questionnaires were completed by the students' parents. Myopia was present in 36.7 ± 0.7% of 4249 students aged 5-14 years old. The prevalence of myopia in girls (38.6 ± 1.1%) was significantly higher than in boys (35.0 ± 1.0 %) (p = 0.015) and increased with age (p < 0.001), with the highest prevalence observed in children aged ≥11 years (67.5 ± 1.8%). After adjustment, having a myopic parent (aOR 3.10; 95% CI 2.49-3.86), incorrect reading posture (aOR 2.09; 95% CI 1.75-2.50), reading a book at a distance of <20 cm (aOR 1.60; 95% CI 1.16-2.21), studying at home for >3 h daily (aOR 1.50; 95% CI 1.12-2.01), studying for >1 h continuously (aOR 1.21; 95% CI 1.02-1.45), and reading extracurricular books that utilize a font larger than that used in textbooks (aOR 0.74; 95% CI 0.59-0.94) were all significantly associated with myopia. The prevalence of myopia among primary school children in Beijing increased with age, and was significantly higher in girls ≥10 years old. Myopia was significantly associated with parental myopia, reading posture, distance between the eyes and the book being read, font size used in extracurricular reading material, time spent studying at home, and the duration of continuous study time.