Abstract Studies at the nexus of immigration, organizations, and migrant mobilizations find that the strategies that immigrant-serving nonprofit organizations (INOs) employ differ in cities with disparate levels of immigrant inclusion. Yet studies yield mixed results abound other shortcomings in the literature. This study draws from disparate literatures and theoretical frameworks to assemble an understanding on the interrelations between local context and strategies. I investigate the following questions: how does the level of citizenry inclusion impact the strategies employed by INOs, and do more inclusive cities facilitate or constrain contentious advocacy? I draw from a national sample of INOs to test the empirical relationship. The results have implications for political opportunity theory and future lines of research drawing from this framework. Research, nonprofit practice, and policy implications are discussed.