s S111 the predictor level was evaluated using the principles of the GRADE approach to rating confidence in effect estimates. RESULTS: Of 10420 studies reviewed, 72 studies evaluating 63 predictors were included. High-quality-evidence independent predictors of mortality was found for age (HR 1.45 for 10-year increase, 95%CI 1.35-1.56), baseline glomerular filtration rate (HR 1.25 for 15-ml/min decrease, 95%CI 1.15-1.35), chronic obstructive pulmonary disease (HR 1.54, 95%CI 1.38-1.71), diabetes (HR 1.56, 95%CI 1.371.79), peripheral vascular disease (HR 1.43, 95%CI 1.21.72), left ventricular ejection fraction (HR 0.77 for 10% increase, 95%CI 0.73-0.83) and the occurrence of appropriate or inappropriate ICD shocks during follow up (HR 1.84, 95%CI 1.43-2.35 and HR 1.55, 95%CI 1.29-1.86, respectively). NYHA class and history of congestive HF were strongly associated with mortality but the quality of their evidence was judged to be low to very low. Ischemic cardiomyopathy and male sex were not independent predictors of mortality. CONCLUSION: This meta-analysis identified strong and reliable mortality predictors in HF patients with an ICD that should be considered at the time of prognosis assessment. The most frequent factors related to low-quality evidence were risk of bias at the study level, unexplained inconsistency, and bias due to selective reporting. 058 A MATCHED CONTROL STUDY TO ASSESS THE EFFECT OF CRT ON RV FUNCTION IN PATIENTS WITH SEVERE LV DYSFUNCTION G Dwivedi, T Haddad, R Abo-Shasha, LM Mielniczuk, T Ruddy, RS Beanlands, M Green, B Chow, H Haddad