In the era of big data, organizations are increasingly leveraging advanced analytics to extract valuable insights from vast and complex datasets. Management Information Systems (MIS) play a crucial role in collecting, processing, and analyzing data to support decision-making. Integrating big data analytics into MIS can enhance business intelligence and improve organizational performance. This study aims to investigate the integration of big data analytics into MIS and its impact on business intelligence. Specifically, the study seeks to identify the challenges and opportunities associated with this integration and explore best practices for implementation. A qualitative research approach was adopted for this study. Data was collected through semi-structured interviews based on a survey of over 312 information technology (IT) professionals from 21 industries with IT managers and business analysts from January 2022 to December 2023. Thematic analysis was used to analyze the data and identify key themes related to integrating big data analytics into MIS. The findings indicate that integrating big data analytics into MIS can significantly improve business intelligence. According to the respondents, on average, there was a 30% increase in the accuracy of decision-making processes after the integration. Additionally, organizations reported a 25% reduction in operational costs and a 20% increase in revenue as a result of the integration. Moreover, 70% of the respondents agreed that integrating big data analytics into MIS improved their organization's overall performance. Integrating big data analytics into MIS offers numerous benefits, including improved decision-making, cost savings, and revenue growth. However, organizations must overcome challenges such as data privacy and security concerns and the need for skilled personnel to manage and analyze big data. Overall, this study highlights the importance of integrating big data analytics into MIS for enhancing business intelligence and achieving organizational success.