Impoverished Conditions Research Articles

Sounds enhance visual completion processes

Everyday vision includes the detection of stimuli, figure-ground segregation, as well as object localization and recognition. Such processes must often surmount impoverished or noisy conditions; borders are perceived despite occlusion or absent contrast gradients. These illusory contours (ICs) are an example of so-called mid-level vision, with an event-related potential (ERP) correlate at ∼100–150 ms post-stimulus onset and originating within lateral-occipital cortices (the ICeffect). Presently, visual completion processes supporting IC perception are considered exclusively visual; any influence from other sensory modalities is currently unknown. It is now well-established that multisensory processes can influence both low-level vision (e.g. detection) as well as higher-level object recognition. By contrast, it is unknown if mid-level vision exhibits multisensory benefits and, if so, through what mechanisms. We hypothesized that sounds would impact the ICeffect. We recorded 128-channel ERPs from 17 healthy, sighted participants who viewed ICs or no-contour (NC) counterparts either in the presence or absence of task-irrelevant sounds. The ICeffect was enhanced by sounds and resulted in the recruitment of a distinct configuration of active brain areas over the 70–170 ms post-stimulus period. IC-related source-level activity within the lateral occipital cortex (LOC), inferior parietal lobe (IPL), as well as primary visual cortex (V1) were enhanced by sounds. Moreover, the activity in these regions was correlated when sounds were present, but not when absent. Results from a control experiment, which employed amodal variants of the stimuli, suggested that sounds impact the perceived brightness of the IC rather than shape formation per se. We provide the first demonstration that multisensory processes augment mid-level vision and everyday visual completion processes, and that one of the mechanisms is brightness enhancement. These results have important implications for the design of treatments and/or visual aids for low-vision patients.

Factors Sustaining Homelessness in a Mentally Ill Patient:A Case Report

People who are living in a place not meant for human habitation, in emergency shelter, in transitional housing, or are exiting an institution where they temporarily resided are called homeless [1]. Despite India’s growing economy, India is home to about 78 million homeless people and about half of homeless people live in Uttar Pradesh, Maharashtra, Rajasthan and Madhya Pradesh [2]. In fact shelter, after food, is considered the most essential ingredient for survival and success. Their is no single factor which can predict homelessness and in majority of the cases, interaction of series of life events over a period of time can lead to this adverse situation. It may not be the occurrence of event, but the affect of the event on the person is more important determinant. In a study conducted by Paul Koegal et al (1995) [3], it was found that two or more predictors were identified in 62% of those homeless interviewed. This demonstrates the highly comorbid nature of experiences that lead to homelessness. The important predictors include disruptive childhood movement (Ravenhill, 2008) [4] physical and sexual abuse during childhood (McIntee & Crompton, 1997;) [5], violence against the child or violence witnessed by the child, living separately from the parents and receiving welfare benefits during childhood, substance abuse within the family (Koegal et al, 1995 [3] and Meller et al ,1988) [6], and disability. Koegel’s study in 1995 reported conditions where individuals would be more likely to end up homeless. The findings showed that 25% of the homeless individuals indicated living separately from their parents at some point in their childhood and 60% reported receiving welfare during childhood and/or living in impoverished conditions with inadequate food or water and another 32% reported that there was a substance abuse within their house.

The effect of transcendental meditation on self-efficacy, perceived stress, and quality of life in mothers in Uganda

ABSTRACTVulnerable women living in poverty in Uganda, who are primarily single, illiterate mothers, face high levels of physical and psychological stress. Our study assessed the impact of the Transcendental Meditation® (TM®) technique on self-efficacy, perceived stress, and mental and physical quality of life of these women. This single-blind controlled study involved 81 women who were assigned to either practice of the Transcendental Meditation program (n = 42) or wait-list (delayed start) control group (n = 39). Participants learned the Transcendental Meditation program over five sessions, then practiced at home for 20 minutes twice a day, and attended twice monthly group meetings over a 3-month period. The primary outcome measure was self-efficacy using the General Self-Efficacy Scale (GSES). Perceived stress using Cohen's Perceived Stress Scale, and physical and mental quality of life using subscales of the Medical Outcomes Survey (MOS, HIV version) were secondary outcome measures. Significant improvements were shown in self-efficacy (p < .001), perceived stress (p < .010), and mental and physical well-being (p < .010). Compliance with TM home practice was >88%. This is the first controlled study to demonstrate the effect of TM in the daily lives of mothers living in impoverished conditions. Further questionnaires were administered to participants at 8 months and at 36 months with questions about changes they may have experienced in their daily life since starting TM. “Yes,” “No” self-reported answers suggested that the women experienced improved health, improved relationships with others, and increased employment rates. These findings taken as a whole have important implications for developing self-efficacy, improving mental and physical quality of life, and reducing stress in the lives of these vulnerable women.

Living condition, weight loss and cognitive decline among people with dementia.

AimsThe aim of this study was to investigate cognitive performance and BMI of patients with dementia living in their own homes with family members, nursing homes and alone.DesignA prospective observational cohort study with a quantitative design.MethodMini–mental state examination (MMSE) scores and BMI were examined with a sample of Slovak patients (N = 428). Patients were followed up 12 months later after the first examination.ResultsCognitive decline was significantly faster for patients living in nursing homes and for solitary patients. BMI consistently decreased in the follow‐up examination and this drop was stronger in patients living alone and in nursing homes. Patients with VaD manifested a stronger BMI decline as compared with AD patients. This study suggests that impoverished conditions such as nursing homes or social isolation of solitary people contribute to stronger progress in dementia. Healthcare professionals need to implement meaningful activities for institutionalized people and for people who are living alone to eliminate the negative impact of an impowerished environment on patient's cognitive functioning.

The interrelationships among pain interference, depressive symptoms, loneliness, and employment status: a moderated mediation study

Objective: To explore the mediating effect of loneliness on the relationship between pain interference and depressive symptoms and to determine whether this mechanism is contingent on employment status. Design: Cross-sectional study. Subjects: A total of 876 adult caregivers of adolescents living in extremely impoverished conditions. Analysis: Mediation and moderated mediation analyses using standard path-analytic approaches. Results: The mean age of the sample was 39.0 (SD = 12.8) years and 80.7% (n = 707) identified as female. Almost half (48.9%, n = 425) of the participants did not report any pain, while 32.5% (n = 285) reported non-disabling pain, and 19.0% (n = 166) reported disabling pain. The mean depressive symptoms score was 16.20 (SD = 10.6), and the mean loneliness score was 40.09 (SD = 10.5). Loneliness mediated the effect of both non-disabling and disabling pain on depressive symptoms. However, the indirect effect of pain interference on depressive symptoms through loneliness was more pronounced among participants reporting disabling pain (coefficient, 2.11; Boot 95% confidence interval (CI) (1.25–3.01)) than non-disabling pain (coefficient, 0.99; Boot 95% CI (0.25–1.76)). Moderated mediation results showed that the indirect effect of pain interference on depressive symptoms, via loneliness varied in magnitude as a function of employment status among participants reporting disabling pain but not those reporting non-disabling pain. Conclusion: Loneliness provides an important link in the relationship between depressive symptoms and pain interference. Furthermore, employment status is an important factor to consider, especially among individuals reporting disabling pain with comorbid depressive symptoms.

Decreased environmental complexity during development impairs habituation of reinforcer effectiveness of sensory stimuli

Previous research has shown that rats reared in simple/impoverished environments demonstrate greater repetitive responding for sensory reinforcers (e.g., light onset). Moreover, the brains of these rats are abnormally developed, compared to brains of rats reared in more complex/enriched environments. Repetitive behaviors are commonly observed in individuals with developmental disorders. Some of these repetitive behaviors could be maintained by the reinforcing effects of the sensory stimulation that they produce. Therefore, rearing rats in impoverished conditions may provide an animal model for certain repetitive behaviors associated with developmental disorders. We hypothesize that in rats reared in simple/impoverished environments, the normal habituation process to sensory reinforcers is impaired, resulting in high levels of repetitive behaviors. We tested the hypothesis using an operant sensory reinforcement paradigm in rats reared in simple/impoverished (IC), standard laboratory (SC), and complex/enrichened conditions (EC, treatments including postnatal handling and environmental enrichment). Results show that the within-session habituation of the reinforcer effectiveness of light onset was slower in the IC and SC rats than in the EC rats. A dishabituation challenge indicated that within-session decline of responses was due to habituation and not motor fatigue or sensory adaptation. In conclusion, rearing rats in simple/impoverished environments, and comparing them to rats reared in more complex/enriched environments, may constitute a useful approach for studying certain repetitive behaviors associated with developmental disorders.

Role of mHealth in overcoming the occurrence of post-stroke depression.

Depression associated with stroke affects roughly one-third of stroke survivors. Post-stroke depression (PSD) is thought to adversely influence functional outcome by limiting participation in rehabilitation, decreasing physical, social, and cognitive function, and affecting neuroplasticity thereby placing stroke survivors at high risk for future vascular events. PSD has also been associated with higher mortality rates after stroke. In Peru, a country where there is no national stroke program and mental health disorders are largely underdiagnosed and untreated, people with PSD are likely to be further challenged by dependency and impoverished conditions that will limit their use of ambulatory services, leading to inadequate clinical follow-up. In this scenario, mobile health (mHealth) technology offers a promising approach to extend access to high-quality and culturally tailored evidence-based psychological care to address PSD given that cell phone use, Internet connectivity, and digital health technology have met a rapid growth in the last years and thus contribute to the attainment of broader Sustainable Development Goals (SDGs). The limited evidence of the effectiveness of mHealth for PSD calls for researchers to fill a knowledge gap where Peru poses as an ideal setting because rapid expansion of digital technology and current mental healthcare reform could be leveraged to enhance post-stroke outcomes. This article proposes the rationale for a suitable evidence-driven, mHealth-based, PSD self-management intervention called iMOODS-Investigating the role of mHealth in overcoming occurrence of depression after stroke-that could be tested among recent stroke patients with PSD in resource constrained settings.

Motivational factors affecting informal women entrepreneurs in North-West Province

Background: Informal women entrepreneurs in the rural villages of North-West strive to progress from poverty to prosperity. There is a growing appreciation that the conditions that support women’s ability to start and grow ventures may be different from those that help men and therefore there is a need to examine the motivational factors affecting women’s enterprise development.Aim: The study aimed to identify the motivational factors of women in the Mahikeng area to start informal enterprises, the barriers they experience and their developmental business needs.Setting: The study focussed on informal women entrepreneurs in the rural villages of Mahikeng in the North-West province.Methods: In total, 80 face-to-face questionnaires were completed with women entrepreneurs. A principal component analysis of 15 items of the total questionnaire was performed on the data to determine which items could be reduced and transformed into new components.Results: ‘Destitute conditions’, ‘Entrepreneurial Spirit’ and ‘Passion for Product’ emerged as the three underlying motivational factors. The component ‘Destitute conditions’ was ranked as the most important reason for starting an informal business. The need to transcend impoverished conditions (a push factor) and the need for self-determination (a pull factor) were almost equally strong amongst the 80 participants. ‘Lack of financial and business skills’ was ranked as the biggest obstacle to keeping the business running. Ninety-one per cent of the women entrepreneurs reported that they had never received any training from the government or the private sector.Conclusions: Access to basic infrastructure, training, funding and business networks will enable self-efficacy behaviour of women entrepreneurs in the Mahikeng district to move beyond poverty. Recommendations included the establishment of a regional database of informal women entrepreneurs, the improvement of basic facilities and infrastructure and access to microloans as well as training by the formal sector.

Organizing effects of adverse early‐life condition on body mass, compensatory growth and reproduction: experimental studies in rock pigeons

Early‐life food conditions can have profound impact on adult behavioural performance. In song birds, early‐life food conditions affect adult physiology and cognitive performance such as song learning and spatial learning. However, effects on reproductive behaviour other than song, such as visual courtship display, pair formation, and egg laying, which are all important determinants of fitness, received hardly any attention. In this study, rock pigeons Columba livia were raised either in a food ad‐libitum or at impoverished (quality) and restricted (quantity) food conditions, in which the latter was applied for either 26 or 8 d after hatching and in slightly different severity. Their growth and reproductive behaviour in adulthood was analysed under semi‐natural conditions. Impoverished and restricted food (IRF) negatively affected adult body mass, pair‐bonding behaviour, courtship (males) and being courted (females), and induced incomplete compensatory growth. Further analyses suggest that the effects of IRF on behaviour could result from the strong effects on body mass, and perhaps also from detrimental effects of compensatory growth. These results provide evidence that adverse early‐life condition can negatively impact on reproductive success, as suggested by the significant effect on egg production, which will very likely lead to a lower life‐time fitness. The detrimental effects on male courtship indicate that IRF can affect sexual displays via other pathways than by impaired cognition as has been suggested for bird song, since courtship in the pigeons is not learned.

Social class and mental distress in Greek urban communities during the period of economic recession.

This study draws on old and well-established evidence that economic change, and especially recession, affects people's lives, behavior and mental health. Even though the literature is rich on the relationship between unemployment and mental distress, there is a renewed research interest on the link between socio-economic inequalities and psychological health. The study investigates the relationship of social class with mental distress during the hard times of persistent and severe economic crisis in Greece by conducting a comparative, community study in the country's second largest city, Thessaloniki. A face-to-face structured interview covering living conditions, life events, chronic stressors and coping strategies was employed to 300 residents of socio-economically contrasting neighborhood areas. Social class was operationalized by Erik Olin Wright's social class position typology, based on ownership and control over productive assets. The method of multiple correspondence analysis (MCA) was also applied to analyze the collected data. The results indicated that mental distress was significantly differentiated across social classes and in each residential area. Unemployed and unskilled workers were the most vulnerable groups in terms of psychological health. Chronic stress arose in this study as a risk factor for poor mental health outcomes and it was associated to low marital quality, intense economic burden and impoverished housing conditions. Those who face income loss, job loss and disability are at high risk for poverty and marginalization, suffering from greater psychological distress.

Abstinence environment contributes to age differences in reinstatement of cocaine seeking between adolescent and adult male rats

Extinction responding and cue-induced reinstatement of cocaine seeking after 60-days of forced abstinence are attenuated in male rats that self-administered cocaine during adolescence, compared with adults. Given that environmental enrichment during abstinence decreases reinstatement among adults, a possible explanation for attenuated reinstatement among adolescents is that standard pair-housing in prior studies creates a more stimulating environment for younger rats. Therefore, we tested whether standard pair-housing is necessary for the attenuated reinstatement among adolescents by determining whether an impoverished environment during abstinence would increase reinstatement among adolescents, up to adult levels. Conversely, we also tested whether environmental enrichment could further decrease reinstatement among adolescents, and whether we could replicate effects of environmental enrichment to decrease reinstatement among adults down to adolescent levels (positive controls). Adolescent and adult male Wistar rats self-administered cocaine intravenously for 12days (fixed ratio 1; 0.36mg/kg per infusion; 2h sessions). Rats were then moved into enriched (grouped, large cages, novel toys), standard (pair-housed, shoebox cages), or impoverished (isolated, hanging cages) housing conditions. After 60days, extinction and cue-induced reinstatement of cocaine seeking were tested, followed by drug-primed reinstatement (0, 5, 10mg/kg cocaine, i.p.). Consistent with previous results, extinction and cue-induced reinstatement were attenuated in adolescent-onset groups compared with adults; this age difference also extended to drug-primed reinstatement. In support of the present hypothesis, an impoverished environment during abstinence increased reinstatement among adolescents to levels that were not different from adult standard-housing levels. These data suggest that abstinence environment influences the enduring effects of cocaine among adolescents as well as adults.

Demystifying the Role of Copyright as a Tool for Economic Development in Africa: Tackling the Harsh Effects of the Transferability Principle in Copyright Law

In the English common law tradition copyright is seen as being in the nature of a property right and thus alienable and transmissible from one person to the other. In contrast, the droit d’auteur system of Continental Europe sees copyright as being an author’s right, which attaches to the personality of the author. However, even in this system a distinction can be made between the monist system (as applies in Germany), which treats both moral rights and economic rights as being inseparable and thus equally inalienable, and the dualist system applicable in France, which distinguishes between moral and economic rights, with the former considered inalienable, while the latter is freely alienable. In this way French law embodies the transferability principle in respect of economic rights, in the same way as the Anglo-American system does. Many countries in Sub-Saharan Africa have inherited copyright laws from their erstwhile colonial masters (whether England or France), resulting in the laws of these countries also embodying the transferability principle. It is argued, however, that the transferability principle has had the inadvertent effect of stifling copyright-based entrepreneurship, and thus economic development in these countries. Because of the conditions of impoverishment prevailing in these countries, authors find that they do not have the material resources to economically exploit their copyright works. They thus have no option but to assign their copyrights to others, mainly foreign entities, resulting in an endless cycle where they can never act entrepreneurially in respect of their copyrights. The paper seeks to explore this phenomenon and make proposals of possible solutions. &#x0D;

The Lasting Effects of American Indian Boarding Schools

How does the American Indian boarding school experience influence the long-run economic development on reservations? To explore this question, I use enrollment data from 1911 to 1932 to construct the historical share of Indian students who attended boarding schools for 175 American Indian reservations. I address endogeneity concerns by exploiting cross-sectional variation in the proximity to a historic boarding school. I find that reservations with a larger share of boarding school students had higher high school graduation rates by the mid-century and those gains persist to the present. This effect is strongest on reservations with weak pre-industrial governance structures and without agricultural traditions. The gains from boarding schooling can be attributed to the benefits of removing children from impoverished conditions and providing a Native-only schooling substitute to U.S. public schools.

Depression and Intimate Partner Violence Among African American Women Living in Impoverished Inner-City Neighborhoods.

Mental health correlates of intimate partner violence (IPV) victimization including negative physical and mental health outcomes are well documented. However, certain subgroups of African American women, such as those living in impoverished, urban communities, are underrepresented in most studies and may experience IPV at higher rates. Furthermore, the circumstances of this women including poverty makes them at risk to IPV and its consequences. The present study estimated the prevalence of IPV victimization and its association with depression in a sample of low-income African American women participating in the Mobile Youth and Poverty Study. Participants in this study were caregivers of adolescents living in extremely impoverished conditions and were part of the Mobile Youth Survey, a community-based, longitudinal, multiple cohort survey conducted between the years 1998 and 2011. Data for the current study were collected between the years 2001 and 2010. The dependent variable was depressive symptoms as measured by the Center for Epidemiological Studies-Depression Scale (CES-D). The independent variable was IPV measured using a subsample of items from the Conflict Tactics Scale. Nearly three quarters (73.6%, n = 489) of the sample experienced some form of IPV and 49.1% (n = 326) had a CES-D depression score of 16 or greater indicating mild to severe depression symptoms. The highest proportion of women who met the CES-D criteria for depression were those experiencing the most severe IPV irrespective of category (i.e., physical, psychological, or combined). Logistic regression analyses showed that women reporting the most severe abuse, irrespective of category, were significantly more likely to meet the CES-D criteria for depression. In addition, low education and receipt of economic assistance were significantly associated with depressive symptoms. The combination of poor economic conditions and IPV may predispose African American women living in impoverished, urban communities to mental health outcomes such as depression.

Principles That Promote Bidirectionality in Verbal Metaphor

Received wisdom holds that there is a basic and intrinsic directionality in metaphor, wherein switching the target and source of a metaphor either leads to a loss of meaning or, if meaningful, is based on different sets of features. Here the authors review experimental literature based on the notion that semantic memory can be conceptualized in a manner similar to Euclidean space, and that properties of this space provide boundary conditions that invite uni- or bidirectionality when concepts are juxtaposed as in metaphor. The authors review three basic components of this space: distance of concepts A and B, varieties of distances (namely, those unique to the concepts themselves and those that are descriptive of higher-order relations), the density of space in which A and B reside, and the nature of such space for concrete and abstract concepts. The authors argue further that metaphor comprehension involves both use of these factors and pragmatic knowledge and that, unfortunately, in the typical psychology experiments, metaphors are presented for processing in impoverished pragmatic conditions. Under these conditions, the main pragmatic knowledge available for use is knowledge available in semantic space (e.g., distance, feature types, concreteness, and density). The authors review and report studies that demonstrate that the information available in semantic space can invite bidirectionality or topic-vehicle asymmetry, and that bidirectionality can be more easily obtained when the metaphors are placed in a discourse context. To date, the influence of semantic density has not been shown in metaphor comprehension, and the authors present the first studies that have examined this variable in metaphor understanding. Future research directions are suggested.

Breeding limits foraging time: evidence of interrupted foraging response from body mass variation in a tropical environment

Birds should store body reserves if starvation risk is anticipated; this is known as an ‘interrupted foraging response’. If foraging remains unrestricted, however, body mass should remain low to limit the predation risk that gaining and carrying body reserves entails. In temperate environments mass gain in female birds during breeding is often attributed to egg formation and mass loss after incubation to flight adaptation or the effect of reproductive workload, rather than as a result of an adaptive interrupted foraging response to the limited foraging time or unpredictable foraging conditions that breeding demands. In tropical environments, foraging conditions vary more within the breeding season than in temperate environments, and so studies in tropical environments are more suited to decouple the potentially confounded effects of increase in body reserves versus egg formation on the body mass of breeding birds. In this study, we test whether breeding results in an interrupted foraging response in a tropical savannah system using body mass data collected over a 15‐year period from female common bulbuls Pycnonotus barbatus. This species breeds both in the wet and dry season, despite fewer resources being available in the dry season. Breeding stage predicted female body mass: body mass peaked abruptly during incubation, but was not closely associated with the egg‐laying stage, and declined during brood rearing. Breeding females were heavier in the dry season than in the wet season. In the dry season, heavier birds were more likely to incubate eggs or brood chicks. These observations suggest that increased body reserves are required to buffer the consequence of limited foraging time or impoverished foraging conditions, which may be most pronounced during incubation and in the dry season, respectively. Such mass increases are consistent with an interrupted foraging response, which may apply to temperate zone birds experiencing foraging restrictions during breeding.

Combating rural poverty through altruism: a model for sustainable education

Nepal, one of the poorest nations, is plagued with high illiteracy rates and child labour. The children that enter the workforce, namely from rural areas, experience inhumane conditions and many enter the human trafficking trade. With a reach of over 100 million people and 68% of beneficiaries crossing the poverty line, micro-financing has proven to be an effective tool at addressing rural poverty. However, there are disadvantages hidden in these statistics, namely usurious interest rates, high enterprise failure rates, and aggressive repayment schemes that cannot only perpetuate impoverished conditions, but can also contribute to them. To address the disadvantages of micro-financing, a model for sustainable education is developed in this paper using altruism theory and the banking monetary multiplier. Through this model: 1) the cycle of poverty can be reduced; 2) literacy rates can be increased; 3) the supply of children that are trafficked abroad can be minimised.

Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil

Critical to the design and assessment of interventions for enteropathy and its developmental consequences in children living in impoverished conditions are non-invasive biomarkers that can detect intestinal damage and predict its effects on growth and development. We therefore assessed fecal, urinary and systemic biomarkers of enteropathy and growth predictors in 375 6–26 month-old children with varying degrees of malnutrition (stunting or wasting) in Northeast Brazil. 301 of these children returned for followup anthropometry after 2-6m. Biomarkers that correlated with stunting included plasma IgA anti-LPS and anti-FliC, zonulin (if >12m old), and intestinal FABP (I-FABP, suggesting prior barrier disruption); and with citrulline, tryptophan and with lower serum amyloid A (SAA) (suggesting impaired defenses). In contrast, subsequent growth was predicted in those with higher fecal MPO or A1AT and also by higher L/M, plasma LPS, I-FABP and SAA (showing intestinal barrier disruption and inflammation). Better growth was predicted in girls with higher plasma citrulline and in boys with higher plasma tryptophan. Interactions were also seen with fecal MPO and neopterin in predicting subsequent growth impairment.Biomarkers clustered into markers of 1) functional intestinal barrier disruption and translocation, 2) structural intestinal barrier disruption and inflammation and 3) systemic inflammation. Principle components pathway analyses also showed that L/M with %L, I-FABP and MPO associate with impaired growth, while also (like MPO) associating with a systemic inflammation cluster of kynurenine, LBP, sCD14, SAA and K/T. Systemic evidence of LPS translocation associated with stunting, while markers of barrier disruption or repair (A1AT and Reg1 with low zonulin) associated with fecal MPO and neopterin.We conclude that key noninvasive biomarkers of intestinal barrier disruption, LPS translocation and of intestinal and systemic inflammation can help elucidate how we recognize, understand, and assess effective interventions for enteropathy and its growth and developmental consequences in children in impoverished settings.

Generalized Anxiety Disorder modulates emotional processing in central and peripheral vision

Generalized Anxiety Disorder (GAD) is associated with an attentional bias toward emotional information leading to behavioral manifestations which need to be clarified. In healthy participants, the emotional visual stimuli have been shown to capture the attentional resources not only in central vision (CV) but also in impoverished visual conditions as those of the peripheral vision (PV). Hence, it seems necessary to study the processing of emotional information and its behavioral impact in both CV and PV. Objective: The aim of this study was to compare, in patients with GAD and in healthy controls (HC), the behavioral impact of the emotional value of natural scenes presented in CV or in PV. Method: Ten patients with GAD and ten HC matched for age, gender and education level were presented with standardized emotional pictures from the International affective Picture System (IAPS). Three groups of 300 pictures (unpleasant, neutral and pleasant) were presented at three visual eccentricities (CV: 0°; PV: -12° and +12°). The 900 trials were split into 4 blocks during which the participants had to fix a cross in the center of the screen and to report the location of the pictures (left, center or right) using a keypad. We analyzed the behavioral responses: reaction time, the accuracy and the Speed-Accuracy Composite Score (SACS) which measures the efficiency of the response, and the dynamic of the cerebral events using the magnetoencephalography (MEG). Results: The reaction times of patients with GAD were reduced when pictures were emotional while those of HC were increased. Besides, while HC showed a lower efficiency when discriminating the location of pictures appearing in CV, patients demonstrated an equal efficiency in CV and PV. An early occipital component (90 ms) was correlated with the emotional effect. Discussion and conclusion: Patients with GAD showed a high sensitivity to emotional visual information, revealed by an improvement of the efficiency when they responded to emotional pictures and by an early occipital activation. Furthermore, while patients showed similar efficiency regardless of the position of the pictures, HC seemed to expend more attentional resources to monitor the peripheral field which appeared detrimental to the CV. Therefore, our data suggest that a large distribution of attentional resources in visual space is easier for anxious patients than for controls.

Understanding genetic breast cancer risk: Processing loci of the BRCA Gist Intelligent Tutoring System

The BRCA Gist Intelligent Tutoring System helps women understand and make decisions about genetic testing for breast cancer risk. BRCA Gist is guided by Fuzzy-Trace Theory, (FTT) and built using AutoTutor LITE. It responds differently to participants depending on what they say. Seven tutorial dialogues requiring explanation and argumentation are guided by three FTT concepts: forming gist explanations in one's own words, emphasizing decision-relevant information, and deliberating the consequences of decision alternatives. Participants were randomly assigned to BRCA Gist, a control, or impoverished BRCA Gist conditions removing gist explanation dialogues, argumentation dialogues, or FTT images. All BRCA Gist conditions performed significantly better than controls on knowledge, comprehension, and risk assessment. Significant differences in knowledge, comprehension, and fine-grained dialogue analyses demonstrate the efficacy of gist explanation dialogues. FTT images significantly increased knowledge. Providing more elements in arguments against testing correlated with increased knowledge and comprehension.