Despite their substantial economies and populations, South Africa and Nigeria encounter significant challenges primarily due to constraints in accessing to agricultural input resources. The study adopts an interpretivist approach, which involves acknowledging reality and making meaningful contributions through qualitative research. As such, secondary data was collected and analysed thematically. This paper delves into the multifaceted nature of food insecurity, highlighted by historical factors, widespread poverty and unemployment, further exacerbated by escalating global food prices. The correlation between exorbitant input expenses and restricted agricultural yields and production, resulting in heightened food prices, is thoroughly explored. Additionally, the review critically examines the influence of climate change on the agricultural sector and its implications for the availability and accessibility of food in rural areas. The narrative in this paper emphasises the imperative of fairness, equity, transparency, and accountability in formulating sustainable strategies to combat these challenges. The paper advocates for contextually appropriate, evidence-based policy approaches, emphasising the significance of collaborations between research institutions and government entities. Such partnerships are crucial for developing efficacious responses to issues like drought, which necessitate comprehensive monitoring systems and mitigation strategies. The role of local government in fostering the growth of agro-based enterprises is underscored, illustrating how local processing of agricultural products can augment revenue, employment, and overall agricultural productivity. The paper also proposes policies to attract private sector investment, such as subsidies for farming equipment and fertilisers, and the development of climate-resilient agricultural technologies that integrate local indigenous knowledge. Lastly, the paper addresses the critical imperative of enhancing the resilience of supply chains against unforeseen disruptions, encompassing natural disasters and market fluctuations. This entails implementing risk management strategies, investing in infrastructure, adopting advanced technologies, and fostering collaboration throughout the supply chain. The paper concludes that such measures are indispensable for ensuring a stable and consistent supply of agricultural products, ultimately benefiting both producers and consumers and contributing to the overarching goal of attaining food security in South Africa, Nigeria, and similar contexts. Keywords: Food security, Rural livelihoods, Strategic policies, Vulnerable communities, South Africa, Nigeria