Cognitive Impact Research Articles

Effect of cognitive bias on the consumption of broiler products in China; the role of information acquisition channels

PurposeBroiler meat is the most commonly used meat product worldwide. Although China is regarded as one of the three largest broiler producers, the per capita chicken consumption remains low. Consumers' cognitive bias and the information acquisition channels are believed to be the main factors contributing to this. This paper aims to discuss the aforementioned issue.Design/methodology/approachTo explore the phenomenon empirically, the current study uses the survey data of 1,056 consumers from China and analyses them using ordered logistic regression.FindingsThe results revealed that consumers' cognitive bias significantly affects their behaviour toward broiler products, and the order of influence is cognitive bias regarding industry cognitive > product nutrition and taste > food safety. The study further revealed that the more diverse the information acquisition channels, the more likely they are to promote consumer behaviour toward broiler chickens. The order of influence of the channels was self-organising > new media > traditional media.Practical implicationsOverall, the findings suggest that the government and enterprises should strengthen and upgrade information channels to boost both the broiler industry and consumer consumption behaviour regarding poultry products.Originality/valueRather than the usual focus on the impact of consumer cognition on consumer behaviour, this study examines the impact of cognitive bias on consumer behaviour. Further, centring on broiler products with high protein, low fat and feed-to-meat ratios, this study explores the reasons the per capita consumption of broiler products in China is far lower than the national average.

Risk Cognition, Social Learning, and Farmers’ Adoption of Conservation Agriculture Technology

Soil degradation and declining soil fertility are prominent issues for sustainable agricultural development in China. Therefore, it is of great significance to promote the adoption rate of conservation agriculture technology. Risk cognition and technology adoption are closely related, but this perspective is rarely focused on, and it is essential to discuss the influence of social learning on the impact. The Loess Plateau is a representative area for promoting and implementing conservation agriculture techniques. By collecting face-to-face survey data from 1268 farmers in Shaanxi, Shanxi, and Ningxia provinces in China, this study used the binary probit model to examine the impact of risk cognition on the adoption of conservation agriculture technology and the influence of social learning on the impact. The results showed that risk cognition has a significant positive impact on the adoption of conservation agriculture technology; social learning significantly enhances the effect of risk cognition on farmers’ adoption of conservation agriculture technology. Both offline practical learning through “learning by doing” and online learning with ICT play an important moderating role in the impact; a high level of social learning enhances risk cognition to a greater extent and promotes enthusiasm for adopting conservation agriculture technology. Therefore, the value of farmers’ risk cognition should be considered in promoting and implementing conservation agriculture technology. Moreover, expanding offline and online social learning channels is crucial to improve farmers’ risk cognition and promote the adoption of conservation agriculture technology.

Whole genome deconvolution unveils Alzheimer’s resilient epigenetic signature

Assay for Transposase Accessible Chromatin by sequencing (ATAC-seq) accurately depicts the chromatin regulatory state and altered mechanisms guiding gene expression in disease. However, bulk sequencing entangles information from different cell types and obscures cellular heterogeneity. To address this, we developed Cellformer, a deep learning method that deconvolutes bulk ATAC-seq into cell type-specific expression across the whole genome. Cellformer enables cost-effective cell type-specific open chromatin profiling in large cohorts. Applied to 191 bulk samples from 3 brain regions, Cellformer identifies cell type-specific gene regulatory mechanisms involved in resilience to Alzheimer’s disease, an uncommon group of cognitively healthy individuals that harbor a high pathological load of Alzheimer’s disease. Cell type-resolved chromatin profiling unveils cell type-specific pathways and nominates potential epigenetic mediators underlying resilience that may illuminate therapeutic opportunities to limit the cognitive impact of the disease. Cellformer is freely available to facilitate future investigations using high-throughput bulk ATAC-seq data.

Finance and intelligence: An overview of the literature

AbstractDo more intelligent investors take better economic decisions than less intelligent ones? Is risk attitude, in particular risk/loss aversion, linked to cognitive ability? Does an investor's cognitive ability impact his/her patience? Is financial performance positively linked to investor's intelligence? These research questions have become highly relevant with the development of behavioral economics and behavioral finance, following the recognition that humans are not homo economicus. This paper reviews the several strands of literature devoted to answering the above questions. We first discuss the barely debated definitions and measures of intelligence/cognitive ability used in psychology, economics, and finance. We then review the results related to the (controversial) link between risk aversion and cognitive ability. We observe that the literature provides clear results for patience; individuals with a higher level of cognitive ability being more patient on average. Finally, we review the contributions linking (successfully or not) portfolio choice and financial performance to cognitive ability.

How Does Epidemic Prevention Training for Pig Breeding Affect Cleaning and Disinfection Procedures Adoption? Evidence from Chinese Pig Farms.

African Swine Fever (ASF) is a highly infectious disease, severely affecting domestic pigs and wild boar. It has significantly contributed to economic losses within the pig farming industry. As a critical component of biosecurity measures, the selection of cleaning and disinfection (C&D) procedures is a dynamic and long-term decision that demands a deeper knowledge base among pig farmers. This study uses a binary logit model to explore the effect of epidemic prevention training on the adoption of C&D procedures among pig farmers with irregular and regular C&D procedures based on micro-survey data obtained from 333 pig farmers from Sichuan. The endogeneity issue was handled using propensity score matching, resulting in solid conclusions. In addition, the critical mediating impact of biosecurity cognition was investigated using a bootstrap analysis. The empirical study demonstrated that epidemic prevention training encourages pig farmers to adopt C&D procedures, with biosecurity cognition significantly mediating. Furthermore, epidemic prevention training was more likely to promote the adoption of C&D procedures among pig farmers with shorter breeding experiences and those having breeding insurance. Our study emphasized the importance of implementing epidemic prevention training to improving pig farmers' biosecurity cognition and promoting the adoption of C&D procedures. The results included suggested references for preventing ASF and the next epidemic of animal diseases.

Influence of posttraumatic stress reaction and posttraumatic cognition on dissociative experiences according to the nature of traumatic experiences: A survey on Japanese young adults.

Although the relationship between dissociation and traumatic experiences has been debated, many studies focus on the context of traumatic experiences. Alternatively, basic research that examines the relationship of symptoms of posttraumatic experiences and cognitive characteristics of dissociation as an individual difference among experiencers has been lacking. To address this research gap, this study examines the influence of posttraumatic symptoms and cognition on dissociative experiences given the nature of traumatic experiences. This study administered the Events Checklist, the Dissociative Experiences Scale (DES), the Impact of Event Scale-Revised (IES-R), and the Japanese version of the Posttraumatic Cognitions Inventory to 1,036 Japanese adolescents. It investigated differences in dissociative experiences according to the presence of and cumulative traumatic experiences. Hierarchical multiple regression analysis was conducted to determine the influence of sex and the nature of traumatic experiences, posttraumatic symptoms (IES-R), and cognition on dissociative experiences. The results demonstrated no differences in DES based on the number of traumatic experiences. Moreover, this study observed the impact of cognition in posttraumatic experience on dissociation. This study provides essential data on the distribution of dissociative experiences among Japanese adolescents with traumatic experiences and exposure to adversity. Finally, it highlights the importance of focusing on posttraumatic cognitive characteristics, particularly negative self-perception, and discusses the implications to enhance understanding of dissociative experiences. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Cognitive impact on patients with COVID-19 infection

BackgroundSARS‐COV‐2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. Coronavirus disease 19 (COVID-19) can cause neuropsychiatric, psychological, and psychosocial impairments. Literature regarding the cognitive impact of COVID-19 is still limited.This study aims to evaluate cognitive function, anxiety, and depression among patients with coronavirus disease 19.MethodsSixty COVID-19 patients were recruited and sub-grouped according to the site of care into three groups, home isolation, ward, and RICU, and compared with 60 matched control participants. Entire clinical history, O2 saturation, mini-mental state examination (MMSE), Hamilton’s anxiety (HAM-A), and depression rating scales (HAM-D) were assessed.ResultsMMSE showed significantly lowest results for the ICU group, with a value of 21.65 ± 3.52. Anxiety levels were the highest for the ICU group, with a highly significant difference vs. the home isolation group (42.45 ± 4.85 vs. 27.05 ± 9.52; p< 0.001). Depression values assessed showed a highly significant difference in intergroup comparison (44.8 ± 6.64 vs. 28.7 ± 7.54 vs. 31.25 ± 8.89; p<0.001, for ICU vs. ward vs. home group, respectively).MMSE revealed a significant negative correlation with age and education level, anxiety level had significant negative correlations with severity of illness and male gender, and depression level had highly significant negative correlations with severity of illness and male gender.ConclusionBoth cognitive and neuropsychiatric symptoms were affected in COVID-19 cases, especially in ICU-admitted patients. The impact of these disorders was significant in older age, lower oxygen saturation, and severe disease.Trial registrationClinicalTrials.gov. NCT05293561. Registered on March 24, 2022.

Impact of depression on the perception of fatigue and information processing speed in a cohort of multiple sclerosis patients

BackgroundInformation processing speed is commonly impaired in people with multiple sclerosis (PwMS). However, depression and fatigue can affect the cognitive profile of patients: fatigue has a negative impact from the disease’s earliest stage and a reduced information processing speed is often associated with higher levels of depression. Therefore, the aim of this study was to investigate the correlations between information processing speed and physical fatigue in a cohort of Italian PwMS from a single center, considering the effect of depression.MethodsTwo hundred (W = 128; mean age = 39.83 years; SD = 11.86) PwMS, from the Bari University Hospital, underwent testing for processing speed (Symbol Digit Modalities Test [SDMT]), fatigue level (Fatigue Severity Scale [FSS]), and depression (Beck’s Depression Inventory [BDI]).ResultsStatistically significant correlations emerged between SDMT and FSS, SDMT and BDI, FSS and BDI. Mediation analyses revealed that while physical fatigue had no significant direct negative effect on information processing speed (z=-0.891; p > 0.05), depression predicted the relationship between fatigue and information processing speed (z=-2.181; p < 0.05).ConclusionOur findings showed that cognitive performance at SDMT was not affected by patients’ perceived level of physical fatigue, but by depression. The presence of a high BDI score mediates the physical fatigue on cognitive performance impact.

“Intangible cultural heritage” label in destination marketing toolkits: Does it work and how?

Attaching the “intangible cultural heritage” (ICH) label to heritage streets is an emerging trend in China. The phenomenon remains unexplored in many countries rich in ICH resources. This study investigates whether labeling ICH is a useful marketing tool and identifies the mechanism behind how label cognition affects the tourist's intention to visit a destination. Results show that cognition about the ICH label, which combines one's level of label awareness, label-related attitudes, and label-associated recall, positively influences behavioral intention. Furthermore, one's emotions regarding the ICH label and the perceived destination image serve as mediators between label cognition and behavioral intention. Lastly, when cultural identity is high, the impact of label cognition is strong in evoking positive emotions, destination image, and behavioral intention. This study offers preliminary empirical evidence for the roles of the ICH label and can inform marketing strategies for ICH-related destinations.

Casual Games, Cognition, and Play across the Lifespan: A Critical Synthesis

Games, including video games have long been associated with both rhetorics of progress and frivolity, simultaneously recruiting efforts to employ games toward furthering cognitive skills, while also eliciting concerns about the decadence of players. Casual games, defined as games with a low barrier to entry and quick play sessions often focus on cognitively-oriented challenges and are perceived by many players to promote cognitive, social, and emotional benefits. Research on the cognitive, social, and emotional impact of casual games now spans games marketed as entertainment, “brain games,” and digital therapeutics; despite these games sharing similar qualities, the bodies of research literature on them remains largely distinct. This review finds little support for the cognitive benefits of playing casual games, with exception of the elderly or those with dementia. This research synthesis finds evidence for the social and emotional benefits of casual games when they are sought for these purposes, played mindfully, and within robust social contexts. However, the same games, when played in different contexts can have negative consequences, consistent with findings from the mindset literature more broadly. Researchers thus should take seriously the context of game play, perhaps treating the emergent phenomena of play as the unit of analysis, rather than the media artifact.

Аксиологические ориентиры в социальной рекламе для российской молодежи

&lt;p&gt;This study aims to clarify the role of axiology in advertising. The axiological component has been considered in the composition of social advertising for young people in present-day Russia. The materials of the analysis (including linguistic analysis) of advertising messages published in the official Telegram channel of the Federal Agency for Youth Affairs (Rosmolodezh) for the first semester 2023 are presented. The results make it possible to point to a number of relevant and socially significant values, which are formed in the minds of the readers of this information source and young citizens of the Russian Federation. It is noted that there is a need for interdisciplinary research to determine the cognitive impact of advertising on consumers.&lt;/p&gt;

Building a Sustainable Brand Relationship: Analysis of Brand Functional Value and Customer Emotional Cognition in Using the MyParmad Application

This study examines the impact of brand functional value and customer emotional cognition on sustainable brand relationships between users and the MyParmad application. The results suggest that functional value has a more significant influence on the sustainable brand relationship than the emotional cognition of the customer. Nevertheless, emotional cognition is still an essential factor in promoting sustainable brand relationships based on the functional value of an application. By considering user feedback and implementing innovative ideas, organizations like Universitas Paramadina can improve their applications' functional aspects and strengthen their service concepts. Brand functional value and emotional cognition affect the formation of these relationships, and organizations like Universitas Paramadina can strengthen their service concepts by considering user feedback and implementing innovative ideas. The study used a purposive sampling technique to gather data from 103 Universitas Paramadina students via an electronic questionnaire during February-March 2023. The survey consisted of 28 Likert scale questions based on previous research on brand functional value, customer emotional cognition, and sustainable brand relationships.

Educational strategies in the health professions to mitigate cognitive and implicit bias impact on decision making: a scoping review

BackgroundCognitive and implicit biases negatively impact clinicians’ decision-making capacity and can have devastating consequences for safe, effective, and equitable healthcare provision. Internationally, health care clinicians play a critical role in identifying and overcoming these biases. To be workforce ready, it is important that educators proactively prepare all pre-registration healthcare students for real world practice. However, it is unknown how and to what extent health professional educators incorporate bias training into curricula. To address this gap, this scoping review aims to explore what approaches to teaching cognitive and implicit bias, for entry to practice students, have been studied, and what are the evidence gaps that remain.MethodsThis scoping review was guided by the Joanna Briggs Institute (JBI) methodology. Databases were searched in May 2022 and included CINAHL, Cochrane, JBI, Medline, ERIC, Embase, and PsycINFO. The Population, Concept and Context framework was used to guide keyword and index terms used for search criteria and data extraction by two independent reviewers. Quantitative and qualitative studies published in English exploring pedagogical approaches and/or educational techniques, strategies, teaching tools to reduce the influence of bias in health clinicians' decision making were sought to be included in this review. Results are presented numerically and thematically in a table accompanied by a narrative summary.ResultsOf the 732 articles identified, 13 met the aim of this study. Most publications originated from the United States (n=9). Educational practice in medicine accounted for most studies (n=8), followed by nursing and midwifery (n=2). A guiding philosophy or conceptual framework for content development was not indicated in most papers. Educational content was mainly provided via face-to-face (lecture/tutorial) delivery (n=10). Reflection was the most common strategy used for assessment of learning (n=6). Cognitive biases were mainly taught in a single session (n=5); implicit biases were taught via a mix of single (n=4) and multiple sessions (n=4).ConclusionsA range of pedagogical strategies were employed; most commonly, these were face-to-face, class-based activities such as lectures and tutorials. Assessments of student learning were primarily based on tests and personal reflection. There was limited use of real-world settings to educate students about or build skills in biases and their mitigation. There may be a valuable opportunity in exploring approaches to building these skills in the real-world settings that will be the workplaces of our future healthcare workers.

Does Cognitive Impairment Impact Motor Learning? A Scoping Review of Elderly Individuals With Alzheimer's Disease and Mild Cognitive Impairment.

Individuals with cognitive impairment may have motor learning deficits due to the high engagement of cognitive mechanisms during motor skill acquisition. We conducted a scoping review to address the quality of current research on the relationship between cognitive impairments (i.e., deficits in attention, memory, planning and executive functions) and motor learning among older adults with Alzheimer's Disease or Mild Cognitive Impairment. After screening thousands of articles, we selected 15 studies describing cognitive assessment tools, experimental designs, and the severity of cognitive impairment. Although seven studies reported that cognitive impairment impaired motor learning, most studies included a high risk of bias. We identified multiple assessment tools across these studies that make comparisons among findings difficult. Future research in this area should focus on the influence of increased practice days during motor learning acquisition and incorporate both retention and transfer tests. Cognitive assessments should target the specific cognitive skills or deficits most closely related to the motor learning process.

“The Use of Universities&amp;#039; Students of One of The Social Media Sites and Its Relation to Cognitive Impacts and Attitudes towards Restriction of Electronic Wastes”

“The Use of Universities&amp;#039; Students of One of The Social Media Sites and Its Relation to Cognitive Impacts and Attitudes towards Restriction of Electronic Wastes”

Cognitive and Affective Impacts of Antistigma Interventions Surrounding People with a Sexual Interest in Children

Prevalent conflation between having a sexual interest in children and engaging in sexually abusive behavior contributes greatly to elevated levels of stigma directed at people living with a sexual interest in children. Contemporary quantitative research employing stigma intervention techniques has produced promising results in decreasing stigmatizing attitudes toward this population. This study aims to expand on this research by qualitatively analyzing the impact of two antistigma interventions. Content and thematic analysis were used to examine N = 460 responses to two open-ended questions featured in an anonymous online survey, which explored the cognitive and emotional impact of the interventions, respectively. A total of nine themes were identified. Four themes pertained to positive/supportive views and emotional responses reflecting the challenging of stereotypes, gaining new perspective, personalized reflections, and recognizing the impacts of stigma. Three themes reflected negative views and emotional responses, which concerned minimization and normalization, adverse personal experiences, and disbelief and mistrust. Finally, two themes reflected mixed views and emotional responses, specifically the difficulty in reconciling emotional and cognitive responses. The data indicated that both interventions showed potential to impact participants’ viewpoints positively. Findings offer insights into how future research can be designed and interventions can be developed more effectively.

The impact of pandemic mental cognition on cultural values: an empirical study based on social media

BackgroundCOVID-19 has triggered a global public health crisis, and had an impact on economies, societies, and politics around the world. Based on the pathogen prevalence hypothesis suggested that residents of areas with higher infection rates are more likely to be collectivists as compared with those of areas with lower infection rates. Many researchers had studied the direct link between infectious diseases and individualism/collectivism (infectious diseases→ cultural values), but no one has focused on the specific psychological factors between them: (infectious diseases→ cognition of the pandemic→ cultural values). To test and develop the pathogen prevalence hypothesis, we introduced pandemic mental cognition and conducted an empirical study on social media (Chinese Sina Weibo), hoping to explore the psychological reasons behind in cultural value changes in the context of a pandemic.MethodsWe downloaded all posts from active Sina Weibo users in Dalian during the pandemic period (January 2020 to May 2022) and used dictionary-based approaches to calculate frequency of words from two domains (pandemic mental cognition and collectivism/individualism), respectively. Then we used the multiple log-linear regression analysis method to establish the relationship between pandemic mental cognition and collectivism/individualism.ResultsAmong three dimensions of pandemic mental cognition, only the sense of uncertainty had a significant positive relationship with collectivism, and also had a marginal significant positive relationship with individualism. There was a significant positive correlation between the first-order lag term AR(1) and individualism, which means the individualism tendency was mainly affected by its previous level.ConclusionsThe study found that more collectivist regions are associated with a higher pathogen burden, and recognized the sense of uncertainty as its underlying cause. Results of this study validated and further developed the pathogen stress hypothesis in the context of the COVID-19 pandemic.

Comparison of manual dexterity of people with Alzheimer’s disease and cognitively healthy older adults: The impact of cognition

AbstractBackgroundAlzheimer’s disease (AD) not only effects the cognitive level, but also leads to significant decline in motor skill. Manual dexterity emerges with the interaction of cognitive and motor processes and is seen as an important predictor of functional independence. The aim of this study was to compare manual dexterity in people with AD with healthy older adults and to investigate the effect of cognitive level on manual dexterity.MethodThe Nine Hole Peg Test (NHPT) was used for manual dexterity assessment. Cognitive function were assessed with Montreal Cognitive Assessment (MoCA). Statistical analysis was performed by Mann Whitney U Test and regression analysis in SPSS 22.0 package program.ResultTwenty nine people with AD (78.04±6.49, 48.27% female) and ten cognitively healthy older adult (74.8±7.22, 30% female) included study. NHPT results of the dominant hand were 31.87±7.33 sec. and 21.66±2.85 sec.; MoCA scores were 13.79±5.76 and 24.5±2.32, respectively, in the people with AD and cognitively healthy older adults. There was significant difference in NHPT results between groups (p&lt;.001). Significant correlation was found between NHPT and MoCA (p&lt;.001, r = .648). It was found that cognitive level significantly predicted manual dexterity (β = .648, R2 = .42, F [1,27] = 19.58, p&lt;.001).ConclusionManual dexterity in AD shows a significant decrease compared to the cognitively healthy older adults. In our study, it was shown that the decrease in manual dexterity occurs with the effect of cognition at a rate of 42%. Deteriorating manual dexterity with decreased cognition is likely to accelerate patients' withdrawal from activities of daily living. Also, rehabilitation programs that include activities for manual dexterity may slow down the process of participation restriction in AD.

Best Practices for Technology in Clinical Social Work and Mental Health Professions to Promote Well-being andPrevent Fatigue.

The shift to communication technologies during the pandemic has had positive and negative effects on clinical social worker practice. Best practices are identified for clinical social workers to maintain emotional well-being, prevent fatigue, and avoid burnout when using technology. A scoping review from 2000 to 21 of 15 databases focused on communication technologies for mental health care within four areas: (1) behavioral, cognitive, emotional, and physical impact; (2) individual, clinic, hospital, and system/organizational levels; (3) well-being, burnout, and stress; and (4) clinician technology perceptions. Out of 4795 potential literature references, full text review of 201 papers revealed 37 were related to technology impact on engagement, therapeutic alliance, fatigue and well-being. Studies assessed behavioral (67.5%), emotional (43.2%), cognitive (57.8%), and physical (10.8%) impact at the individual (78.4%), clinic (54.1%), hospital (37.8%) and system/organizational (45.9%) levels. Participants were clinicians, social workers, psychologists, and other providers. Clinicians can build a therapeutic alliance via video, but this requires additional skill, effort, and monitoring. Use of video and electronic health records were associated with clinician physical and emotional problems due to barriers, effort, cognitive demands, and additional workflow steps. Studies also found high user ratings on data quality, accuracy, and processing, but low satisfaction with clerical tasks, effort required and interruptions. Studies have overlooked the impact of justice, equity, diversity and inclusion related to technology, fatigue and well-being, for the populations served and the clinicians providing care. Clinical social workers and health care systems must evaluate the impact of technology in order to support well-being and prevent workload burden, fatigue, and burnout. Multi-level evaluation and clinical, human factor, training/professional development and administrative best practices are suggested.

White matter hyperintensities in strategic tracts for cognitive impairment: A multicenter lesion‐symptom mapping study in 3525 memory clinic patients

AbstractBackgroundWhite matter hyperintensities (WMH) due to small vessel disease (SVD) are associated with dementia risk. Previous studies suggest that the cognitive impact of WMH depends on location. However, these studies were potentially limited by moderate brain lesion coverage. We aimed to identify strategic WMH locations for cognitive impairment in memory clinic patients by performing a large‐scaled multicenter study providing unprecedented lesion coverage.MethodIndividual patient neuropsychological and MRI data from eleven memory clinic cohorts were harmonized. Voxel based lesion symptom mapping‐ (VLSM) and region of interest (ROI) based analyses were performed to identify strategic WMH locations for four cognitive domains (attention and executive functioning, information processing speed, verbal memory, and language). A strategic WMH score was calculated based on quartiles of WMH volumes in the strategic white matter tracts and was related to cognition using Lasso regression, accounting for multicollinearity, and multivariable linear mixed models.ResultThe combined sample consisted of 3525 patients (age: 71.6 ± 9.0 years; 49.9% female) (Table 1). The WMH prevalence maps are shown in Figure 1. In the merged study sample, 63.0% of the supratentorial white matter was affected by WMH in ≥5 patients and could be included in the VLSM analysis. In the VLSM analysis, statistically significant voxels were found for each of the four cognitive domains, after correction for total WMH volume and multiple testing. These voxels were mostly located in the left and right anterior thalamic radiation and the forceps major. Independent ROI based analysis confirmed these strategic tracts and additionally identified the left inferior fronto‐occipital fasciculus as significant tract (Table 2). The strategic WMH score was significantly associated with lower performance on attention &amp; executive functioning (B‐0.146; p&lt;0.001), information processing speed (B‐0.090, p = 0.023), language (B‐0.124, p = 0.003), and verbal memory (B‐0.128, p&lt;0.001), independent of total WMH volume, age, sex, education, brain parenchymal fraction, and study site.ConclusionThis large multicenter study provides strong evidence that the cognitive impact of WMH in memory clinic patients depends on location and identified four significant white matter tracts. With further refinement, WMH location might become a useful diagnostic biomarker for SVD‐related cognitive impairment.