Introduction Persistent intracoronary thrombus following plaque rupture is associated with an increased risk of subsequent myocardial infarction and mortality (Svilaas et al. N Engl J Med 2008;358:557-67). Clinically, coronary thrombus can only be visualized invasively by x-ray angiography (XRA), intravascular ultrasound, or angioscopy while preclinical studies with a fibrin-binding MR contrast agent have demonstrated the feasibility of non-invasive MR coronary thrombus imaging (Botnar et al. Circulation 2004). In addition, non-contrast enhanced T1 weighted MRI has been shown useful for direct imaging of carotid thrombus and intraplaque hemorrhage by taking advantage of the short T1 of methemoglobin present in acute thrombus and intraplaque hemorrhage (Moody et al. Circulation 2003;107:3047-3052).