Idiopathic Calcinosis Cutis Research Articles

Diffuse Idiopathic calcinosis cutis: a case report in a 13-year-old Syrian boy.

Calcinosis cutis is characterized by the deposition of calcium salts in the skin and subcutaneous tissue. It is divided into the following subtypes: dystrophic, metastatic, iatrogenic, idiopathic and calciphylaxis. In this case, we report a 13-year-old Syrian boy with idiopathic calcinosis cutis, the lesions were unusually widespread, unlike the common condition which is usually localized to one area. The case was unrelated to any systemic or local disorders, and the patient had no complications, so no treatment was planned.As the best of our knowledge, there are very few cases of diffuse or widespread idiopathic calcinosis cutis. We analyzed the clinical, laboratory, radiographical and pathological characteristics of our patient, which helped us to reach the final diagnosis. We will discuss the pathogenesis, investigation and management of this disease.

Characterizing calcinosis cutis in a pediatric population.

Calcinosis cutis is the abnormal deposition of calcium in the skin and subcutis. There is currently a paucity of data surrounding pediatric calcinosis cutis. The objective of this study is to characterize calcinosis cutis in a pediatric cohort. A single-institution retrospective cohort study was performed over a 5.5-year period. Thirty cases were identified. Calcinosis cutis was found to be more common in men (63%), with a younger median age of onset (5years) compared to women (10years). Dystrophic calcinosis cutis (43%) was the most common type in the study population, though idiopathic calcinosis cutis (37%) was nearly as common. No cases of metastatic calcinosis cutis were found. The etiology of calcinosis cutis in the study population was found to be similar to that identified in adults with the exception of metastatic calcinosis cutis, which was not seen in our cohort. Previous recommendations using laboratory testing to diagnose this disease process might not be as critical as previously thought.

Idiopathic calcinosis cutis in a young female

Idiopathic calcinosis cutis in a young female

Surgical Management of Scrotal Calcinosis: A Case Report and its Ayurvedic Relevance

Idiopathic calcinosis cutis is usually localized to a specific area such as the genital area or chest. Scrotal calcinosis is a rare, benign entity defined as the presence of multiplecalcified nodules within the scrotal skin. The cause is not well defined. In this case study surgical management and its Ayurvedic review of scrotal calcinosis is explained. This is a case of 40 years old male patient with complaints of multiple whitish nodules at scrotal skin since 4 years. There was no evidence of any cystic swelling around calcified Nodule. Ideally for scrotal calcinosis the choice of treatment is excision of calcinosis along with skin followed by suturing or skin graft. As per Ayurveda, the word Granthi is derived from word granthitha which literary means knotted or filled with. The etiological factors constitute the vitiated doshas which in turn affect the blood, muscular tissue and fatty tissue. In this case, Kapha slowly accumulates at the site were muscular and fatty tissue are vitiated and gives rise to round, elevated and slightly nodular swelling which is termed as KaphajaGranthi which is correlated with Scrotal calcinosis

Calcinosis Cutis of the Vulva: A Review.

Idiopathic calcinosis cutis (CC) is an uncommon skin condition. Although it has been reported many times in the scrotum, it is exceedingly rare in the vulva. Most reports of vulvar CC are in children. Vulvar CC may be thought clinically to be inclusion cysts. Other causes of calcinosis such as autoimmune disease or alterations in serum calcium levels, potentially associated with malignancy, must be considered before considering a case as idiopathic.

Congenital idiopathic calcinosis cutis with aplasia cutis congenita

Calcinosis cutis is a disorder characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. It is separated into five subtypes, namely dystrophic calcification, metastatic calcification, idiopathic calcification, iatrogenic calcification, and calciphylaxis. Idiopathic calcification occurs without any underlying tissue damage or metabolic disorder. We here report a rare case of congenital idiopathic calcinosis cutis associated with aplasia cutis congenita.

Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature

BackgroundAbnormal deposition of calcium in the skin or subcutaneous tissue is termed calcinosis cutis. Idiopathic calcinosis cutis of the scrotum is an uncommon entity. The pathogenesis of idiopathic calcinosis cutis of the scrotum is debatable. The condition presents as several brown to yellowish nodules on the scrotum, gradually progressive, and mostly asymptomatic. Here we report a case of idiopathic calcinosis cutis of the scrotum with a brief review of the literature and a discussion on pathogenesis.Case presentationA healthy looking, 50-year-old Nepali man presented with multiple growths on his scrotum for 15 years, which were mostly asymptomatic with an occasional complaint of itching. On physical examination, multiple pink to brown nodules ranging in size from 0.5 × 0.5 × 0.5 cm to 3 × 3 × 1 cm, which were painless and firm in consistency, were noted. On laboratory examinations the following were found to be within normal limits: serum calcium, phosphorus, parathyroid hormone, and vitamin D hormone levels; uric acid; alkaline phosphatase; and lipid profile. Based on clinical features and laboratory reports, a diagnosis of idiopathic calcinosis cutis of the scrotum was made. The nodules were excised under local anesthesia in several sittings, which gave a good cosmetic result with no evidence of recurrence in 1-year follow-up period. A histopathological examination revealed dermis with areas of fibrosis and calcification along with numerous multinucleated giant cells and an absence of any cystic structure.ConclusionsIdiopathic calcinosis cutis of the scrotum is a benign condition, which remains mostly asymptomatic. It presents as progressive multiple nodules of varying numbers and sizes. A histopathological evaluation reveals areas of calcification. The cause is either dystrophic calcification of cysts or idiopathic. Excision is the treatment of choice.

Milia‐like idiopathic calcinosis cutis and plaque‐type syringoma in a girl with Down syndrome

Milia‐like idiopathic calcinosis cutis and plaque‐type syringoma in a girl with Down syndrome

Idiopathic Calcinosis Cutis of Scrotum: A Rare Case Report, Evaluation and its Surgical Management

Idiopathic Calcinosis Cutis of Scrotum: A Rare Case Report, Evaluation and its Surgical Management

Dermoscopy is useful for the diagnosis of milia‐like idiopathic calcinosis cutis

Dermoscopy is useful for the diagnosis of milia‐like idiopathic calcinosis cutis

Milia-like calcinosis cutis in a girl with Down syndrome

Milia-like idiopathic calcinosis cutis (MICC) is a very rare dermatological disorder characterized by multiple whitish to skin colored, milia-like papules, mostly found on the hands. MICC can disappear spontaneously by adulthood; therefore, its early recognition is crucial to avoiding unnecessary interventions. Herein, we present a case of MICC in a 6-year-old girl with Down syndrome.

A Case of Refractory Idiopathic Tumoral Calcinosis Cutis

A case of idiopathic tumoral calcinosis cutis in a normocalcemic patient. The lesions were localized to multiple large and small joints throughout the body and confirmed on biopsy. The lesions are refractory to intralesional steroids, aluminum hydroxide and diltiazem after 5 months. The patient is being considered for surgical intervention for large lesions while he will be further tried on dialitiazem for the smaller ones.Nepal Journal of Dermatology, Venereology & Leprology, Vol.14(1) 2016, pp.44-47

Milia-like idiopathic calcinosis cutis in a child with Down syndrome

Idiopathic calcinosis cutis refers to progressive deposition of crystals of calcium phosphate in the skin and other areas of the body, in the absence of any inciting factor. Idiopathic calcinosis cutis may sometimes take the form of small, milia-like lesions. Most commonly, such milia like lesions are seen in the setting of Down syndrome. Herein, we report a 5-year-old girl with multiple asymptomatic discrete milia-like firm papules distributed over the face and extremities. A diagnosis of milia-like idiopathic calcinosis cutis associated with Down Syndrome was provisionally made and was confirmed by histopathology and karyotyping.

Traitement chirurgical de la calcinose scrotale en un temps

Idiopathic calcinosis cutis is a rare condition involving the development of scrotal nodules in the skin and subcutaneous tissue. Although it is a benign disease, patient's quality of life can be importantly impaired. We report herein our experience and surgical management of diffuse scrotal calcinosis. From 2012 and 2015, 7 patients who suffered of diffuse scrotal calcinosis cutis were included in this study. We performed a one-staged resection of the lesions by an elliptic resection centered on the scrotal median raphe as a scrotal lift shape. Outcomes including sexual quality of life and patient's satisfaction were assessed with a questionnaire. No postoperative complication occurred. Aesthetic result was high and sexual quality of life was importantly improved. No recurrence was observed in a 2-year follow-up. This disease is a pathological condition of unknown origin and hence is idiopathic. Multi-staged resection of the nodules are often performed despite being a time-consuming and expensive approach. Our one-staged treatment increased the patient's quality of life and self-esteem. We present a one-staged treatment of scrotal calcinosis cutis that is simple and effective. Aesthetic and functional results were achieved. 5.

FNAC of Bilateral Iliac Idiopathic Calcinosis Cutis: A Rare Case Report

We report a case of idiopathic calcinosis cutis diagnosed by fine needle aspiration cytology in a 70 year old female who presented with subcutaneous swellings near the bilateral iliac crests. Cytological finding of amorphous calcium salts with histiocytes and the appropriate clinical background led to the cytodiagnosis of idiopathic calcinosis cutis as subsequently confirmed on histopathology. Pitfalls in the diagnosis of calcinosis cutis on cytology smears are also discussed

Milia-like idiopathic calcinosis cutis and syringomas in patient with Down syndrome

Milia-like idiopathic calcinosis cutis and syringomas in patient with Down syndrome

Idiopathic Calcinosis Cutis of Scrotum

A 45 year old male presented with multiple, painless, hard nodular swelling over scrotum of two years duration. The nodules gradually increased in size. There was no history of trauma or any systemic illness. A provisional diagnosis of sebaceous cyst of scrotum was made. His haematological and biochemical parameters were normal. En-block excision of lesion was done. Histopathological diagnosis of calcinosis cutis was made and confirmed by Von Kossa stain. We report herewith a case of idiopathic calcinosis cutis of scrotum and review the literature regarding pathogenesis and management.

稗粒腫様特発性皮膚石灰沈着症を合併した Down 症候群の1例

稗粒腫様特発性皮膚石灰沈着症を合併した Down 症候群の1例

Milium-like Idiopathic Calcinosis Cutis: Report of a Case and Analysis of the Pathogenesis on Reviewing 29 Cases

Milium-like Idiopathic Calcinosis Cutis: Report of a Case and Analysis of the Pathogenesis on Reviewing 29 Cases

Milia-like idiopathic calcinosis cutis of the medial canthus

Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin and may be classified as dystrophic, metastatic, idiopathic or iatrogenic calcification, and calciphylaxis. Idiopathic calcinosis cutis occurs without any underlying tissue damage or metabolic disorder. In this paper, the authors report a new case of idiopathic calcinosis involving the medial canthus of the left eye that was mistaken for milia. An 18-year-old previously healthy male patient, presented with an asymptomatic whitish solitary tumour of the medial canthus of the left eye. The patient had no systemic or trauma history, and the serum levels of calcium and phosphorous were normal. An excisional biopsy was performed and histopathologic examination revealed subepidermal calcinosis. Calcinosis cutis is a rare condition that should be included in the differential diagnosis of a benign-appearing lesion of the face. While it can occur in patients with a history of inflammation, trauma, or hypercalcemia, its etiology can also be idiopathic.