Hypertrophic Lupus Research Articles

Dramatic Efficacy of Oral Aromatic Retinoid in Long-standing Hypertrophic Lupus Erythematosus

Dramatic Efficacy of Oral Aromatic Retinoid in Long-standing Hypertrophic Lupus Erythematosus

Hypertrophic lupus erythematosus: a clinicopathological study of 14 cases.

Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of lupus erythematosus (LE). It is characterized by verrucous lesions, chronic in its course, and resistant to treatment. The purpose of this study was to identify clinical and histological characteristics of HLE. We review our experience with 14 cases of HLE identified in a group of 220 patients with different forms of LE, at the UNICAMP Hospital, between 1976 and 2002. All patients presented verrucous plaques concomitantly with discoid lesions. The most common sites of involvement were the face and the arms. Histology of HLE lesions revealed pseudoepitheliomatous hyperplasia engulfing elastotic material. Elastic fibers were seen in migration throughout the epidermis. Classic features of LE were noted in all cases. Three of the patients developed hyperkeratotic papules with central keratinous plug on their arms at the previous LE sites. These lesions resemble clinically and histopathologically keratoacanthomas. In one patient, HLE lesion progressed to squamous cell carcinoma (SCC), 26 years after the onset of the disease. Transepithelial elimination of the elastotic material may be a feature of HLE. Some HLE lesions may present as keratoacanthoma, but classical features of LE aid the correct diagnosis. SCC may arise on a long-standing HLE lesion; therefore HLE requires clinical and histopathological follow up.

Hypertrophic lupus vulgaris of 67 years' duration

British Journal of DermatologyVolume 131, Issue 1 p. 142-143 Hypertrophic lupus vulgaris of 67 years' duration C. Goicoechea, C. Goicoechea Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorP. Ruiz-Avila, P. Ruiz-Avila Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorE. Soler, E. Soler Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorM.Bustos de Abajo, M.Bustos de Abajo Pathology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorJ. Linares, J. Linares Pathology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorJ. Abad, J. Abad Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorR. Naranio, R. Naranio Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this author C. Goicoechea, C. Goicoechea Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorP. Ruiz-Avila, P. Ruiz-Avila Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorE. Soler, E. Soler Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorM.Bustos de Abajo, M.Bustos de Abajo Pathology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorJ. Linares, J. Linares Pathology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorJ. Abad, J. Abad Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this authorR. Naranio, R. Naranio Dermatology Service, University of Granada Hospital, E-18071 Granada, SpainSearch for more papers by this author First published: July 1994 https://doi.org/10.1111/j.1365-2133.1994.tb08478.xCitations: 7AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume131, Issue1July 1994Pages 142-143 RelatedInformation

(15) Hypertrophic lupus erythematosus

British Journal of DermatologyVolume 119, Issue s33 p. 72-74 (15) Hypertrophic lupus erythematosus Drs D.C. Buck, Search for more papers by this authorH.J. Dodd, Search for more papers by this authorI. Sarkany, Search for more papers by this author Drs D.C. Buck, Search for more papers by this authorH.J. Dodd, Search for more papers by this authorI. Sarkany, Search for more papers by this author First published: July 1988 https://doi.org/10.1111/j.1365-2133.1988.tb05418.xCitations: 14AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume119, Issues33July 1988Pages 72-74 RelatedInformation

Successful treatment of hypertrophic lupus erythematosus with isotretinoin

A patient with systemic lupus erythematosus had the additional finding of hypertrophic lupus erythematosus. The lesions cleared with an 11-week course of isotretinoin alone. She has remained without recurrence for 9 months. This is the first reported case of total resolution of hypertrophic lupus erythematosus with a short course of isotretinoin.

EDINBURGH ROYAL INFIRMARY.: HYPERTROPHIC LUPUS OF THE VULVA ; COMPLICATION WITH PREGNANCY

EDINBURGH ROYAL INFIRMARY.: HYPERTROPHIC LUPUS OF THE VULVA ; COMPLICATION WITH PREGNANCY