Hypertension In Elderly Research Articles

The Effect of Ergonomic Exercise on Reducing Blood Pressure in Hypertensive Elderly at Ciparay Panti Sosial Tresna Werdha Ciparay

Hypertension is a condition when blood pressure is at 140/90 mmHg or more. Every year people with hypertension continue increased, it is estimated that in 2025 as many as 1.5 billion people suffer from hypertension... One way to reduce blood pressure is to do ergonomic exercises. The purpose of this study is to find out ergonomic exercises for decreasing blood pressure on elderly hypertension at Ciparay Elderly Social Rehabilitation Institution. This research used quasi Experiment design by designing a pre and post test group. The population of this study was hypertensive elderly totaling 70 people, The sampling technique uses non probability sampling with the technique purposive sampling, its about 23 respondent. Data collection using questionnaires, observation sheets, and digital sphygmomanometer. The number of respondents was 23 respondents, ergonomic exercises done 3 times repeatedly - according to 3 weeks. Pressure measurement blood is done before gymnastics (pre test) and after 30 minutes after gymnastics (post test). Statistical test results show the average systole pressure before gymnastics is equaldari to160.15 mmHg to and the remaining gymnastics 140.05 mmHg, a decrease of 20.1 mmHg. Diastolic pressure before gymnastics isfrom 96.28 mmHg and as is gymnastics to 86.11 mmHg, a decrease of 10.17 mmHg. Data analysis using Paired Sample T-Test related to ergonomic exercises for impairment blood pressure in hypertensive elderly with systole pressure p value = 0,000 and diastolic pressure p = 0,000.The conclusion Can be accessed the effect of ergonomic exercises on reducing blood pressure in elderly hypertension. The results of ergonomic exercise intervention can be used as a therapy in pressure reduction blood and it is expected that the elderly are routinely approved for ergonomic exercises.

Relationship between Exercise with Blood Pressure Stability among Hypertension Elderly

Objective: This study aims to determine the relationship between elderly gymnastics and blood pressure stability in elderly hypertension in Porpri Posyandu Lansia Bunulrejo. Methods: This research is correlated with a cross-sectional approach. Samples were chosen by using the purposive sampling technique with inclusion and exclusion criteria, which got 25 people. The variables measured in this study were the elderly gymnastic relationship and blood pressure stability. The test statistic used was spearman rank correlation with a 95% confidence level. Results: The results of bivariate analysis showed that there was a significant correlation between daily gymnastics and stabilizing blood pressure (p = 0,000), with a correlation strength of 0,710. Conclusion: From the research results, it can be concluded that there is a relationship between elderly gymnastics and blood pressure stability in people with hypertension.

Analysis of Elderly Group Community Nursing Practices with Education Innovation Interventions of LSM (Lansia Sehat Merata) among Elderly with Hypertension

Elderly is a natural process accompanied by a decrease in physical, psychological and social conditions that interact with each other. The attachment of conditions that influence each other causes the elderly to be included in a vulnerable group that needs more monitoring than other age groups. High blood pressure is considered a major risk factor for developing heart disease and various vascular diseases in older people. Through health education efforts, people behave or adopt health behaviors by way of persuasion, appeals, solicitations, and so on. The purpose of this paper is to analyze community nursing care for elderly groups with educational innovation interventions (NGOs) for hypertensive elderly people on the level of knowledge in Sodong Hamlet, Tambaksari Village, Tambaksari Health Center Working Area in 2022. The population used is all hypertensive elderly in Sodong Hamlet, Tambaksari Village, as many as 155 people. The sampling method for nursing care is non-probability sampling. While the technique used is accidental sampling. The results of the nursing analysis found that there was an effect of health education on the level of knowledge in elderly hypertensives after educational interventions were carried out Lansia Sehat Merata.

Intervensi Senam Lansia terhadap Tekanan Darah pada Lansia Hipertensi

This study aims to determine the effect of elderly exercise on blood pressure in elderly hypertensives at the Tresna Werdha Social Institution, Bengkulu City. This study used Quasy Experiment with one Group pre-and post-test design. The results showed that there was a decrease in systolic and diastolic blood pressure before and after being given gymnastics for older people with an average systolic of 143.00 mmHg to 132.73 mmHg, while diastolic 85.20 mmHg to 77.60 mmHg. The independent t-test statistical test results obtained a p-value of 0.058 systolic and 0.069 diastolic. In conclusion, there is an effect of elderly exercise intervention on reducing blood pressure in hypertensive elderly.
 Keywords: Elderly Gymnastics, Blood Pressure

Promosi Kesehatan Tentang Covid-19, Pencegahan Dan Penanganan Hipertensi Pada Lansia

Human Development Index has three elements, they are health, education attained and standard of living or often called the economy. Knowledge regarding the prevention and handling of COVID-19 and Hypertension in Elderly needs to be disseminated to reduce the number of COVID-19 cases considering the spread of this virus between humans and humans. The incidence of hypertension was also quite a lot and major cause of degenerative disease. The incidence of COVID-19 in West Nusa Tenggara (NTB) Province has also experienced a significant increase since the announcement of the first positive cases on March 24, 2020. On April 21, 2020, there were 108 cases, with 11 recovered and 4 people. die. The number of COVID-19 sufferers in Mataram was 43 cases, while hypertension cases in Mataram, especially in Pondok Perasi, were 41 people. Health education need to be attention for society regarding the prevention and control the spread of COVID-19 and Hypertension increases knowledge and urges the public to suppress the chain of spread of the Corona Virus which can cause COVID-19 and prevent recurrence of hypertension in the elderly. The target of this public service was the Community in the Bintaro Ampenan, Mataram, the aim of this public service was to providing the understanding of community about counseling on the prevention of covid-19, washing hands properly, and providing materials for the prevention of covid-19 transmission by distributing free masks and counseling on hypertension. These activities have been carried out well. The response from residents was very good and they hoped that similar activities were carried out regularly

Health Education Model for Elderly Hypertension on Knowledge, Attitudes, and Adherence to Following the Dietary Approaches to Stop Hypertension (DASH)

Health Education Model for Elderly Hypertension on Knowledge, Attitudes, and Adherence to Following the Dietary Approaches to Stop Hypertension (DASH)

Effect of stroke education with video on stroke prevention behavior in hypertension elderly in Cipayung health center area east Jakarta

Stroke is a cerebrovascular disease and is a worldwide problem. Stroke is the third leading cause of death. The purpose of this study was to determine the effect of stroke education with video on stroke prevention behavior in elderly hypertensives. This research method uses a quasi-experimental pre-post test only design. The population in this study were hypertensive elderly who visited the Elderly Posyandu. The sampling technique in this study used purposive sampling, with a total sample of 31 respondents. Methods of data collection by pre-post test and blood pressure examination. Analysis of research data using univariate analysis, and bivariate analysis using the dependent t.test statistic, while multivariate analysis using logistic regression tests. The results of the study showed that there was an effect of stroke education through video on knowledge of stroke prevention in elderly with hypertension (p = 0.002). There was no effect of stroke education through video on stroke prevention attitudes in elderly hypertension (p = 0.86). There is an effect of stroke education through video on stroke prevention skills in elderly with hypertension (p = 0.003). There is an effect of stroke education through video on systolic blood pressure in elderly with hypertension (p = 0.000).

Investigating the Availability of Nutrition Management Service for Hypertensive Elderly People in Khubetsoana and Thamae Health Centres

Many elderly people have hypertension, and health systems are faced with the challenge of responding to the needs of this population. The availability of Nutrition Management Service (NMS) in Out Patient Department (OPD) services is one of the strategies that have the potential to control these patients' blood pressure. The study sought to investigate the availability of NMS for the hypertensive outpatient elderly in Thamae Health Centre and Khubetsona Health Centre. The study was a descriptive cross-sectional study employing both qualitative and quantitative data collection methods. NMS was found to be available in the facilities, but incomplete. Of all the patients followed, 16.2% received nutrition counseling and 9.5% received nutrition follow-up, but none of them received nutrition screening. NMS is available in the facilities but it is incomplete, due to many factors which originate from the planners' failure to plan for it.

ELECTROLYTES AND VITAMINS IN HYPERTENSION. UPDATE 2023

Objective: Essential hypertension is the most common internal disease in Germany. This disease can result in a variety of cardiovascular diseases like myocardial infarction, heart insufficiency, or stroke. In this context, electrolytes and vitamins are of growing interest. Especially an existing deficiency in electrolytes or vitamins has to be avoided. Due to malnutrition or medical treatment, a loss in electrolytes and vitamins can occur. Therefore the elderly hypertensive is at a special risk. Design and method: 45 elderly (beyond 65 years) hypertensives (23 male, 22 female) patients were studied. None of the patients was renal insufficient, diabetic or under diuretics or supplemented with biofactors for at least 6 weeks before study. Electrolytes (sodium, potassium, calcium and magnesium in serum, in addition ionized magnesium in blood) and vitamin D and interleukin 6 were measured. Ionized magnesium was measured by a NOVA Prime plus apparatus, NOVA BIOMEDICAL, Andover, USA. Data are means +/- SD. ANOVA was used for statisdtical analysis. Results: Sodium, potassium and calcium values were measured normal in each patient. Serum creatinine was below 1.2 mg/dl in all patients. In seerum magnesium concentrations, only 1 subject had values below 1,5 mg/dl, all other elderly hypertensives had a normal serum magnesium concentration. In contrast, ionized magnesium concentrations were significantly decreased in 15 of 45 patients, showing values below 0.5 mmol/l (py< 0.01), that is 30%. Vitamin D levels were also significantly decreased, 17.6 +/- 6.1 ng/ml as compared to the normal values (> 20 ng/ml)(p< 0.01). Interleukin 6 levels were significantly increased (5.52 +/- 3.38 pg/ml)(normal range below 2 pg/ml)(p< 0.01). Conclusions: In elderly hypertensives electrolyte disorder has to be corrected. A magnesium deficiency is observed in elderly hypertensives in about 30%, due to recent literature. In our study we can confirm these findings concerning ionized magnesium, too. Interleukin 6 levels were found significantly increased, depending on a sufficient magnesium content. Vitamins A, C, E and K can reduce oxidative stress, B vitamins are protective for vessels and neurons. Vitamin D (in our study reduced)(in combination with magnesium) can reduce blood pressure, too.

INCREASED IONIZED CALCIUM-MAGNESIUM RATIO IN ELDERLY HYPERTENSIVES

Objective: Alterations in the metabolism of calcium and the biofactor magnesium can be involved in the pathogenesis of essential hypertension. Serum magnesium concentrations only insufficiently reflect disorders in magnesium handling in humans, as only about 1% of total body magnesium stores are in blood. The calcium and magnesium flux across the external membrane is regulated by a calcium pump (calcium-magnesium-ATPase), calcium and magnesium (TRPM 6 and 7) channels and a sodium magnesium antiport. An increased calcium-magnesium ratio is known to be involved in the development of atherosclerosis. Early onset of this disorders are known in hypertension. Design and method: We present a study in 18 hypertensive elderly concerning ionized magnesium concentrations and ionized calcium-magnesium ratio in blood measured by a Prime Plus apparatus by NOVA Medical, Andover, USA. Results: In 18 elderly hypertensives (9 male/9 female with normal renal function) ionized magnesium was measured 0.55 +/- 0.04 mmol/l (normal range: 0.54 - 0.80 mmol/l). The ionized calcium-magnesium ratio was 2.33 +/- 0.18 (normal range below 2.40)(p< 0.05). Data are means +/- SD. ANOVA was used for statistical evaluation. About 40% of elderly hypertensives showed an significantly increased ratio of ionized calcium and magnesium, which is well known to be a marker for the development of arteriosclerosis. Conclusions: As described earlier, a deficiency in the biofactor magnesium can be involved in the pathogenesis of essential hypertension. Ionized magnesium data, as presented here, are rare, but ionized magnesium is the active magnesium in the body regulating about 600 enzymatic reactions. The significantly increased ratio of ionized calcium and magnesium is important in the development of arteriosclerosis often resulting in stroke or heart insufficiency in hypertension.

REMNANT CHOLESTEROL AND INTENSIVE BLOOD PRESSURE CONTROL IN OLDER PATIENTS WITH HYPERTENSION: A POST HOC ANALYSIS OF THE STEP RANDOMIZED TRIAL

Objective: Emerging evidence shows the close relationship between remnant cholesterol (RC) and hypertension. However, it is unknown whether RC is associated with the effect of intensive systolic blood pressure (SBP) lowering on cardiovascular outcomes. We aimed to determine the influence of baseline RC on the effect of intensive SBP lowering in hypertensive patients. Design and method: We performed a post-hoc analysis of the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial. Participants were randomly allocated to intensive SBP treatment (110 to <130 mmHg) or standard SBP treatment (130 to <150 mmHg). RC was calculated as total cholesterol minus high-density lipoprotein cholesterol minus low-density lipoprotein cholesterol. The median RC concentration was used to categorize participants into low and high RC groups. The primary outcome was a composite of stroke, acute coronary syndrome, acute decompensated heart failure, coronary revascularization, atrial fibrillation, or death from cardiovascular causes. Results: Of the 8,511 participants in the STEP trial, 8,276 participants had available baseline RC concentrations (low RC group: n = 4,200; high RC group: n = 4,076). After a median follow-up of 3.33 years, a reduction in the primary outcome was observed in participants allocated to receive intensive SBP lowering in both groups; however, the reduction was only significant in the high RC group (high RC group: adjusted hazard ratio [aHR] 0.62; 95% confidence interval [CI] 0.45–0.84; low RC group: 0.91 [0.67–1.24]; P for interaction = 0.09). Intensive SBP treatment decreased all-cause mortality in the high RC group (aHR 0.48; 95% CI 0.28 – 0.81) but increased it in the low RC group (aHR 2.51; 95% CI 1.47 – 4.28; P for interaction <0.001). Among the adverse events, only hypotension was slightly increased in the high RC group (adjusted relative risk 1.48; 95% CI 1.02 – 2.16). Conclusions: Patients with high RC experienced greater cardiovascular benefits with intensive SBP lowering.

THE INFLUENCE OF BASELINE DIASTOLIC BLOOD PRESSURE ON THE EFFECTS OF INTENSIVE BLOOD PRESSURE LOWERING: RESULTS FROM THE STEP RANDOMIZED TRIAL

Objective: The Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial reported cardiovascular benefits of intensive systolic blood pressure (SBP) lowering. However, the influence of baseline diastolic blood pressure (DBP) on the effects of intensive SBP lowering on cardiovascular outcomes has not been fully elucidated. Design and method: In this post hoc analysis of the STEP trial, participants were randomly assigned to receive intensive (110 to <130 mmHg) or standard SBP treatment (130 to <150 mmHg) and categorized by baseline DBP into subgroups: <70, 70 - 79, and > = 80 mmHg. The primary outcome was a composite of stroke, acute coronary syndrome, acute decompensated heart failure, coronary revascularization, atrial fibrillation, or death from cardiovascular causes. A competing risk proportional hazards regression model was used in the analysis. We compared results across subgroups stratified by baseline DBP levels by including a multiplicative interaction term between SBP treatment arms and subgroups (treatment arm* subgroup). Results: Of the 8,511 participants, 960, 2,474, and 5,077 had baseline DBP divided in intervals of <70, 70 - 79, and > = 80 mmHg, respectively. A reduction in the primary outcome was observed among those randomized to intensive SBP lowering in each DBP subgroup but was significant only in the subset of participants with baseline DBP > = 80 mmHg (<70 mmHg: adjusted hazard ratio, 0.81 [95% confidence interval, 0.43 - 1.51]; 70 - 79 mmHg: 0.80 [0.55 - 1.15]; > = 80 mmHg: 0.73 [0.54 - 0.97]). There were no significant interactions between SBP treatment and baseline DBP subgroups for the primary and secondary outcomes (all P for interaction >0.05). The sensitivity analyses showed consistent results with the main analysis. Conclusions: Baseline DBP levels did not modify the beneficial effects of intensive SBP lowering on cardiovascular outcomes.

Intensive Blood Pressure Lowering Improves Left Ventricular Hypertrophy in Older Patients with Hypertension: The STEP Trial.

Intensive systolic blood pressure (SBP) lowering has been increasingly used; however, its effect on cardiac remodeling remains not fully understood. This secondary analysis of the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients trial aims to determine the changes in left ventricular hypertrophy (LVH) that occur in the context of intensive SBP lowering. A total of 7141 older patients with hypertension were randomly assigned to intensive treatment (SBP target, 110-130 mm Hg) or standard treatment (130 to 150 mm Hg). LVH was defined according to the Peguero-Lo Presti criteria on a standard 12-lead ECG. At baseline, the prevalence of LVH (16.6% versus 16.5%) and the mean Peguero-Lo Presti value (1811 versus 1808 μV) were comparable between the treatment groups. During a median follow-up of 3.24 years, intensive SBP lowering was associated with a significantly lower risk of new LVH occurrence (hazard ratio, 0.76 [95% CI, 0.66-0.89]; P=0.001) and slower progression of the mean Peguero-Lo Presti index value by -23.47 μV/y (95% CI, -34.93 to -12.01; P=0.000). However, the rates of regression of baseline LVH did not differ significantly. Of note, the beneficial effect of intensive SBP lowering in terms of cardiovascular events (hazard ratio, 0.75 [95% CI, 0.59-0.97]) was not markedly attenuated after adjusting for LVH as a time-varying covariate (hazard ratio, 0.76 [95% CI, 0.59-0.97]). Intensive SBP lowering protects against LVH development in older hypertensive patients, however, this favorable effect could not explain most of the reduction in cardiovascular events associated with intensive SBP lowering.

Relationship between Compliance with Routine Examination and Quality of Life in Elderly Hypertension

Indonesia has entered an elderly population period with the highest prevalence of hypertension of the entire national population. Hypertension control strategies focus on improving the quality of life for each sufferer so that they can maintain their quality of health independently. Compliance with routine check-ups is a national strategy for controlling cases of hypertension in the elderly. This study aims at the relationship between adherence to routine checks and the quality of life of hypertensive elderly people in the working area of ​​the UPT Puskesmas Tanjung Redeb. From the results of this study, it was found that there was a significant relationship between adherence to routine checks and quality of life for elderly hypertensives in the working area of ​​the UPT Puskesmas Tanjung Redeb (Sig = 0.000; OR = 4.765).

The Correlation between Body Mass Index, Physical Activity and Blood Pressure with Quality of Life in Elderly Hypertension

Hypertension is a global and national health problem known as the silent killer," which continues to increase. Community-based preventive promotion efforts are a strategy for controlling hypertension, especially in the elderly, through Posbindu activities and routine health check-ups. This study aims to determine the relationship between body mass index, physical activity, and blood pressure and the quality of life of hypertensive elderly people in the working area of ​​the UPT Puskesmas Tanjung Redeb. This research is a type of correlational quantitative research with a cross-sectional design. The results showed that there was a significant relationship between BMI (p-value 0.629), physical activity (p-value 0.000), and blood pressure (p-value 0.013) and quality of life in the elderly. Good quality of life is accompanied by an increase in BMI to near normal, physical activity to near normal, and blood pressure to near normal.

Cytomorphological findings of Trichophyton rubrum infection in an elderly hypertensive woman.

Trichophyton is a dermatophytic fungi causing superficial skin infections which affects outermost layer of the epidermis, stratum corneum, and mainly involves feet, groin, scalp, and nails. Invasion into the dermis occurs mainly in immunocompromised patients. A 75-year-old hypertensive female presented with a nodular swelling on the dorsum of right foot for 1 month. The swelling was 1.0 × 1.0 cm and gradually progressive in nature. FNAC revealed many thin filamentous branching and fungal hyphae along with foreign body granulomas and suppurative acute inflammation. The swelling was excised and sent for histopathological examination which confirmed the above findings. Periodic Acid Schiff stain showed fungal hyphae in both cytology smear as well as histopathology section. On fungal culture, microconidia with septate hyphae suggestive of Trichophyton rubrum was seen. Trichophytons mainly affect immunocompromised and diabetic patients, however, may present as nodular lesions without any history of superficial dermatophytosis as seen in the present case. The characteristic cytological picture helped to clinch the diagnosis in this case and facilitated further management.

The Relationship of Risk Factors to the Incidence of Hypertension in Pre-Elderly and Elderly (Study in Ternate City)

hypertension, is a chronic disease. Every day, the number of cases of hypertension in pre-elderly and elderly is increasing, and it can have a variety of consequences, including: reduced quality of life, difficulties in social and physical functioning, and increased pain and mortality due to complications. This study aims to identify the relationship between risk factors and the incidence of hypertension in the elderly and geriatric population in the city of Ternate. This study was a cross-sectional study using univariate and bivariate analyzes, to determine the relationship between risk factors and the incidence of hypertension in pre and elderly individuals. Samples were selected by cluster random sampling technique and using blood pressure checks and questionnaires containing structured questions. This study was conducted in the Ternate Public Health Center (PUSKESMAS) with 299 respondents from pre-elderly and elderly aged ≥45 years old. The research uncovered five factors that with a significant relationship with hypertension. Those factors are age, family history, salt intake, obesity, and dyslipidemia. On the other hand, there are three factors that have no significant relationship with hypertension, which is gender, smoking habits, and alcohol consumption.

Insulin resistance drives cognitive impairment in hypertensive pre-diabetic frail elders: the CENTENNIAL study.

Pre-diabetes is a condition that confers an increased cardiovascular risk. Frailty is very common in hypertensive patients, and insulin resistance has been linked to frailty in older adults with diabetes. On these grounds, our aim was to evaluate the association between insulin resistance and cognitive impairment in hypertensive and pre-diabetic and frail older adults. We studied consecutive pre-diabetic and hypertensive elders with frailty presenting at the Avellino local health authority of the Italian Ministry of Health (ASL AV) from March 2021 to March 2022. All of them fulfilled the following inclusion criteria: a previous diagnosis of hypertension with no clinical or laboratory evidence of secondary causes, a confirmed diagnosis of pre-diabetes, age >65 years, Montreal Cognitive Assessment (MoCA) Score <26, and frailty. We enrolled 178 frail patients, of which 141 successfully completed the study. We observed a strong inverse correlation (r = -0.807; P < 0.001) between MoCA Score and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). The results were confirmed by a linear regression analysis using MoCA Score as dependent variable, after adjusting for several potential confounders. Taken together, our data highlight for the first time the association between insulin resistance and global cognitive function in frail elders with hypertension and pre-diabetes.

Visit-to-Visit Blood Pressure Variability and Cardiovascular Outcomes in Patients Receiving Intensive Versus Standard Blood Pressure Control: Insights From the STEP Trial.

The clinical prognostic value of visit-to-visit blood pressure (BP) variability (BPV) is debatable, and relative studies among patients receiving BP control to achieve lower BP targets are limited. We analyzed a dataset from the STEP trail (Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients) to investigate the relationship between visit-to-visit BPV and cardiovascular events in patients with hypertensive aged 60 to 80 years. Visit-to-visit BPV was defined as the coefficient of variation, SD, delta, average real variability, and variability independent of the mean of BP measured at 6-, 9-, 12-, 15-, and 18-month follow-up visits. We computed hazard ratios for the risks associated with a 1-SD increase in BPV indexes in multivariable cox regression models. Among 7678 patients from the STEP trial, after adjustment for multiple confounders, diastolic BPV indexes were significantly associated with the primary composite end point (hazard ratios ≥1.21; P≤0.029) in the standard group, while there was no association between the clinical outcomes and systolic BPV (P≥0.091). In the intensive treatment group, either systolic or diastolic BPV was no association with clinical outcomes(P≥0.30). Sensitivity analyses using an alternative method to calculate BPV based on 7 BP records generated confirmatory results. In older adults with hypertension, visit-to-visit diastolic BPV is an independent predictor of adverse health outcomes in the standard treatment group. However, BPV did not have prognostic value in the intensive treatment group. URL: https://www. gov; Unique identifier: NCT03015311.

Achieved systolic blood pressure and cardiovascular outcomes in 60-80-year-old patients: the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial.

Intensive systolic blood pressure (SBP) lowering has been increasingly used; however, data is missing on patients who had target-achieved (TA). This study aims to show the cardiovascular effect of maintaining SBP at intensive levels. The Strategy of Blood Pressure Intervention in Elderly Hypertensive Patients (STEP) trial was a multicentre, randomized, controlled trial which enrolled 8511 young-older (60-80 years) hypertensive patients without prior stroke to compare the cardiovascular prognosis of the intensive treatment (SBP target, 110 to <130 mmHg) vs. the standard treatment (130 to <150 mmHg). This secondary analysis assessed data in patients who achieved a mean SBP within target values. The association of mean achieved SBP and cardiovascular events was examined using a cubic spline function. In total, 3053 patients (72.0%) in the intensive-treatment group and 3427 (80.3%) in the standard-treatment group had an SBP target achieved, with mean follow-up SBP values of 124.2 mmHg and 137.4 mmHg, respectively. Throughout the median 3.38-year follow-up, the cardiovascular risk was significantly lower in the TA intensive-treatment group than in the TA standard-treatment group [adjusted hazard ratio (HR) 0.61, 95% confidence interval (CI) 0.46-0.80; P < 0.001]. In the intensive-treatment group, patients failing to achieve SBP targets presented higher cardiovascular risk than those TA patients (HR 2.04, 95% CI 1.44-2.88; P < 0.001). A J-shaped relationship was observed between the mean achieved SBP and risk of cardiovascular events, with the lowest risk at an SBP of 126.9 mmHg. Maintaining SBP at <130 mmHg offers additional cardiovascular benefits among young-older patients with hypertension. ClinicalTrials.gov: NCT03015311.